Deputy Director Research Articles

Interview with Journal of Cell Science Editor Kairbaan Hodivala-Dilke

ABSTRACT Kairbaan Hodivala-Dilke is a Professor of the Tumour Microenvironment at Barts Cancer Institute (BCI) at Queen Mary University of London, UK. She completed her PhD with Professor Fiona Watt at The Imperial Cancer Research Fund (ICRF), UK, before moving to The Massachusetts Institute of Technology, USA, for a postdoc in Professor Richard Hynes’s lab. She then joined Cancer Research UK in 1999 as a tenure-track fellow under the mentorship of Professor Ian Hart and has since become Deputy Director of BCI and a member of the European Molecular Biology Organization and The Academy of Medical Science. She currently leads the Centre for Tumour Microenvironment at BCI, where her research focuses on understanding the roles of cell adhesion and angiocrine signalling in cancer and responses to therapy. Kairbaan (who is also known as Kebs) joined Journal of Cell Science as an Editor in August 2023, and brings to the journal her extensive expertise in cancer cell biology, angiogenesis and signalling within the tumour microenvironment. We spoke with Kebs over Zoom to learn about her impressive career, her perspectives on scientific publishing and her philosophy of leadership in academia.

A Multifaceted Scientist: a Bio-bibliographic Portrait of A.Yu. Samarin

The review of the eleventh issue of the series “Russian Historians of Science and Technology”, published since 2005 under the auspices of the S.I. Vavilov Institute for the History of Natural Science and Technology of the Russian Academy of Sciences (IHNST RAS), is presented. It is called “Samarin Alexander Yuryevich: materials for bio-bibliography” (Moscow, 2023) and is dedicated to the 50th anniversary of A.Yu. Samarin, the famous historian of books and book business, bibliographer and librarian, historian of science, organizer of research, Deputy Director General for Scientific Publishing of the Russian State Library, Doctor of Historical Sciences, Honored Worker of Culture of the Russian Federation. He has also been successfully cooperating with the IHNST RAS for a long time, being concurrently the chief researcher of the Department of Historiography and Source Studies of the History of Science and Technology. The review reveals the main content of this collection, which in a multidimensional and multifaceted way shows the role and place of A.Yu. Samarin in organizational, scientific and educational activities for the benefit of the Russian book culture, as well as introduces readers to little-known details of his life path. Special attention is paid to the diverse author and editorial activities of A.Yu. Samarin (including as editor-in-chief of the Bibliography magazine, which, after the inclusion of the Russian Book Chamber in ITAR-TASS, was published as an independent publication in 2015—2020). It is concluded that the publication of the index is an important milestone in the development of book, library and bibliographic knowledge about the history, current state and prospects of Russian book culture.

An Assessment of Solid Waste Management in Ikenne Local Government Area of Ogun State, Nigeria

Background: Sanitation has remained an important and long standing global public health challenge, especially in middle and low income countries. Efforts have been made, and are still being made at finding a total solution to the problems of waste management by successive governments in Nigeria, but none has been fruitful. This study assessed solid waste management in Ikenne Local Government Area of Ogun State, Nigeria. Methodology: For the purpose of this research, a qualitative approach was adopted. This approach employed the use of a Key Informant Interview (KII) and a Focus Group Discussion (FGD). The study was carried out in Ikenne Local Government Area, one of the existing local council areas in Ogun State, the Southwestern part of the country. Twelve personnel of the Water and Environmental Sanitation (WES) department of Ikenne Local Government Area were interviewed for the purpose of this study. The sample consists of the director, deputy director, three chief environmental officers, two senior environmental officers, and five field workers. Results: The respondents stated that there are just two collection trucks servicing the entire five communities. The stress placed on these vehicles would only last for a short while as they are liable to break down. The department also lacks personal protective equipment for health attendants, which ought to help them prevent infectious diseases in the course of performing their duties. Households from the three different communities have shown their dissatisfaction towards the services rendered to the communities by the WES department. They voiced out their displeasures during the focused group discussions where most of them said they are rarely served, even on environmental sanitation days. These options revolve around seeking a redress to institutional constraints. Lack of reliable funding system has affected a lot of functions that ought to be carried out by environmental officers. It all comes down to a single factor – fund. The provision of official vans for inspection purposes, collection trucks, manpower (skilled and unskilled) and other tools are all determined by availability of funds. Conclusion: The study was able to establish that institutional constraint is the major factor militating against solid waste management systems in Ikenne Local Government Area. Every finger points towards this direction and so also the institution admits to this fact. When there is no collection vehicle to carry wastes, the available ones can only serve a few of the population. This is not to say that manpower to collect wastes from households is less important, as they are needed to transfer the wastes into the trucks and also dispose of them, as the services rendered to the people.

MORAL LEARNING STRATEGIES AT MADRASAH MU'ALLIMAAT MUHAMMADIYAH YOGYAKARTA DURING THE COVID-19 PANDEMIC

Moral material becomes an essential thing in education. During the Covid-19 pandemic, the education sector changed policy. Every teacher must determine learning strategies following existing conditions, especially moral teachers who must use the right approach to transfer knowledge and instill morals in students optimally. This research was conducted to describe the learning strategies applied by the moral teachers of Madrasah Mu'allimaat Muhammadiyah Yogyakarta and the accompanying constraints. The type of research used is qualitative research with a descriptive approach. This study used respondents consisting of seven people as informants, namely two moral teachers, the deputy director of the curriculum section, and four students of Madrasah Mu'allimaat Muhammadiyah Yogyakarta. Then, interviews and documentations were data collection techniques used by researchers—analysis of data processing using data reduction procedures, data presentation and conclusion. Based on the research results obtained, the learning strategy used by the moral teachers at Mu'allimaat Muhammadiyah Yogyakarta during the Covid-19 pandemic was expository and active learning. As for the obstacles faced, namely the limitations of space, time (class hours), resources (network and IT devices), and the need for more motivation of the students. Even though there were several obstacles, they could be handled/appropriately resolved. This research has limitations, including the difficulty of arranging interview schedules because it is hindered by semester holidays and the school is busy accepting new students. The recommendation from this study is that teachers must be more able to manage classes optimally, especially by using suitable approaches and strategies. With this research, it is hoped that it can become a reference and reference for further similar research.

Ling-Ling Chen: RNA has its own features; don’t study it as a protein

Abstract Non-coding RNA (ncRNA) has been a very active research area over the past 30 years. From small ncRNA – the discovery of RNA interference won the lead researchers the Nobel Prize, to long ncRNA (lncRNA), which has attracted much attention in recent years, various ncRNAs participate in all kinds of biological processes and show a variety of biomedical application prospects. Recently, National Science Review (NSR) interviewed Ling-Ling Chen, a professor at the Center for Excellence in Molecular Cell Science (CEMCS) of the Chinese Academy of Sciences (CAS), deputy director of the State Key Laboratory of Molecular Biology and director of the CAS Key Laboratory of RNA Science and Engineering, to talk about the magic world of RNA. Ling-Ling Chen and her team have been studying ncRNA for more than 10 years, and have witnessed and promoted the development of this field. They discovered unconventional lncRNAs without polyadenylated (polyA) tails or N7-methylguanosine (m7G) caps, including sno-lncRNAs (small nucleolar lncRNAs), SPAs (5' snoRNA capped and 3' polyadenylated RNAs) and circRNAs (circular RNAs), and have made remarkable progress clarifying the biogenetic mechanisms and functions of these RNAs and exploring their biomedical application. Chen said: ‘I am 45 years old. I hope I will not stagnate here, but make new discoveries.’

School Financial Management in Meeting Infrastructure Standards (Case Study at SMP Negeri 17 in Serang City)

The purpose of this study was to analyze and understand the fulfillment of school financial management facilities and infrastructure standards at SMP Negeri 17 Kota Serang. This research uses a qualitative approach with case studies. The informants in this study consisted of school principals, deputy director of facilities and infrastructure (wakasek), treasurers of Education Unit Operational Assistance (BOSP), and school committees. Data collection techniques were carried out through interviews, observation and documentation. Data analysis techniques use data reduction, data display and verification inference. Information accuracy is verified; credibility, transferability, reliability, and verifiability. The results of the study show that school financial management in meeting educational facilities and infrastructure standards for SMP Negeri 17 Serang City through planning and budgeting, administration and reporting and accountability according to Permendikbudristek 63 BOSP Juknis Year 2022. This study influences the importance of financial management to meet institutional and infrastructure standards education, because Stakeholders both internal and external can assess, analyze, monitor and fulfill various school needs.

ON THE ANNIVERSARY OF OLGA NOVIKOVA

On 20 August 2023, Olga Novikova, Doctor of Economics, Professor, Deputy Director for Research at the Institute of Industrial Economics of the National Academy of Sciences of Ukraine, Full Member of the Academy of Economic Sciences of Ukraine, celebrated her anniversary. Her working life is a vivid example of selfless service to the national economic science for the sake of Ukraine’s prosperity.

Rancang Bangun Aplikasi Inventory Berbasis Website Pada Kreasitex Jakarta

This study aims to design and build an inventory application that can support buying and selling activities at the Kreasitex Jakarta company. Ms. Margaretha Christie served as a resource person in this study to provide information regarding research needs as a deputy director of the company. The waterfall design method is used in this study and uses the javascript and golang programming languages. The functionality testing method is used to test the application. The result of this research is the development of an inventory application that simplifies the buying and selling process and helps record the stock of goods. This inventory system is also useful in managing goods purchased by customers. This application supports the development of the company wit h its good functionality. Overall, this study concludes that this inventory application supports the activities of buying and selling, storing, recording, and managing stock of goods. With the inventory application, the sales process becomes more practical and efficient.

From bottom-up to top-down

Deputy director of the School of Computing at the Australian National University, Amanda Barnard talks to Hamish Johnston about research at the interface of computational modelling, applied machine learning and artificial intelligence.

Structural Equation Modeling of Casual Factors of Effectiveness of Enrichment Program of Science, Mathematics, Technology and Environment (SMTE) of Secondary School in the Northeast Region

The purposes of this research were 1) to study characteristics of causal factors in Structural Equation Modeling (SEM) influencing the effectiveness of science, mathematics, technology, and environment (SMTE) of Secondary Schools in the northeast region, 2) to examine the causal factors of SEM the selected developed model affecting the effectiveness of SMTE in the northeast with the empirical data, and 3) to obtain guidelines for developing the selected factors that affected the effectiveness of science, mathematics, technology, and environment special classroom project in the northeast. This study consisted of 561 related persons involved, consisting of 11 people involved in the project, 1 school director and 1 deputy director, 3 science teachers, 3 mathematics teachers and 3 teachers in computer subjects. The research methodology was conducted in 3 phases: 1) constructing the hypothesis model, 2) examination of conformance with empirical data, and 3) finding ways to develop causal factors. The tools used for the collection were a questionnaire with a five rating scale and an interview form. Statistics used for data analysis were percentage, mean, standard deviation, Pearson’s coefficient, Alpha coefficient, and the analysis of structural equation modeling. The results of the research were as follows: 1) The structural equation modeling that was created consisted of causal variables, namely school management and participation of parents and student’s physical environment in teaching and learning science and mathematics; 2) The causal factors of structural equation modeling of the project effectiveness; 3) This research presents guidelines for the development of causal factors that directly, indirectly, and overall affect the project effectiveness as follows: school management, The participation of parents and students, the physical environment and science and mathematics teaching and learning management.

FOLLOWING THE SCIENTIFIC FOOTPRINTS (GLORIOUS PAGES OF THE LIFE PATH) OF THE OUTSTANDING CRIMINOLOGIST AND FORENSIC EXPERT, ACADEMICIAN MYKHAILO YA. SEHAI

Mykhailo Ya. Sehai was born on March 31, 1923. He fought in World War II against fascist aggression and was awarded orders and many medals. After demobilization, he worked for many years at the Kyiv Scientific Research Institute of Forensic Expertise of the Ministry of Justice of Ukraine, including 20 years as Deputy Director for Research. He went from junior researcher to acting director of the institute. He practised as a forensic expert and conducted scientific research. After retiring, he worked at the Kyiv Regional Center of the National Academy of Legal Sciences of Ukraine. He died at the age of 90 on May 01, 2013. He defended his thesis for the degree of candidate of legal sciences on the use of forensic identification in certain types of forensic examinations. Mykhailo Sehai defends his dissertation for the degree of Doctor of Laws already on the methodology of judicial identification, substantiating it from the standpoint of philosophy. In the next large-scale work, Mykhailo Sehai addresses issues not only of forensic identification but also diagnostic and situational expert tasks. Subsequently, Mykhailo Sehai takes part in the creation of the world’s first law on forensic examination, which combines the rights and obligations of a forensic expert in various types of legal proceedings. Thus, the foundation is laid for the creation of the profession of a forensic expert. Mykhailo Sehai develops the foundations of forensic expertology as a science of forensic activities, including the legal and organizational foundations of this activity, and also generalizes the methodology as part of forensic expertology to three interdisciplinary exercises. The article mentions the teacher of Mykhailo Sehai and the continuation of his work. At the end of the article, it is concluded that Doctor of Law, Professor, and Academician of the National Academy of Legal Sciences of Ukraine Mykhailo Sehai has been following the path of generalizing previous experience throughout his scientific life, from considering a separate issue to systematizing it and systematizing the views from which this issue is being studied. Thus, briefly, this path can be characterized as follows: from the particular to the general. Mykhailo Sehai has made an invaluable contribution to the development of forensic science and forensic science.

In Memoriam: Prof. Valerii Viktorovych Vit

The legendary professor Valerii Viktorovych Vit passed away on April 22, 2023. He was born in Odesa in 1948. After graduating from the Faculty of General Medicine, Odesa Medical Institute, in 1972, Vit worked some time as a dissector at Odesa Regional Hospital. He began his science career at the Filatov Institute of Eye Diseases and Tissue Therapy in 1975 as a junior research associate at the Pathomorphology Laboratory, became head of the laboratory in 1978 and was promoted to the Deputy Director for Science at the institute in 1991. Valerii Viktorovych Vit defended his Cand Sc (Med) thesis in 1978, and doctoral (Dr Sc (Med)) dissertation, The Pathological Anatomy and Therapeutic Pathomorphosis of Human Pigmented Uveal Tumors, in 1986. The dissertation research was conducted under Professor V.V. Voino-Yasenetskyi, an outstanding scientist, and focused on the morphogenesis and malignancy of human choroidal and ciliary tumors. Valerii Viktorovych Vit was promoted to professorship in 1989. He authored or co-authored about 400 papers and five monographs on visual system structure and the pathological anatomy of eye disease. Five individuals completed their Dr Sc (Med) degrees, and 18, their Cand Sc (Med) degrees, under the supervision or mentorship of Prof. Vit. He was the first to raise questions on the value of ocular oncology studies on (a) the transformation of an eye tumor in the course of treatment and (b) the efficacy of the therapy used for treatment. He will be remembered as an exceptionally talented doctor, scientist and manager of high competence and great professional experience and a person with a strong commitment to work. By his pupils and colleagues, Professor Vit, a true professional in his field, will remain a cherished memory. We offer our condolences to his family and loved ones.

کرنل ڈاکٹر ابدال بیلا بحیثیت سیرت نگار: منہجی و اسلوبیاتی مطالعہ

The God Almighty blessed Pakistan with precious diamonds. These diamonds are forces of Pakistan. It is only because of these forces that was spend peaceful life. These soldiers spend their whole lives to protect borders of our country. We are always proud of them. Our soldiers are not only successful in performing their duties, they also express their feelings and emotions through their writings. There are many literary names in our army that painted the land of literature with the pen. In literature they have created such master pieces, for which their names will remain till the end of this universe. These master pieces are good addition in literature. Among one of these military men, one famous name is Col. Abdal Bela. Doctor Abdal Bela was born on 14 December 1956 in Sialkot. Your father's name was Chaudhry Fazal Din. Who was a resident of Ludhiana. And came to Pakistan at the time of establishment of Pakistan. Abdal Bela received his primary education and college education from Lahore. Apart from this, he also studied from Faisalabad Punjab Medical College. He started his career in Pakistan Army as MBBS Doctor, Captain. He also served in Pakistan Navy and Saudi Army. In 2007, Abdal Bela retired from serving Pakistan as Deputy Director ISPR Primary education sailkot. After that, he obtained degrees in nutrition, journalism, and MBA from other educational institutions. Commissioned as Captain in Pakistan Army on 21 June 1980, promoted to Colonel in 1999. Retired from the army in December 2008, Abdal Bela wrote more than 10 books and his books have been translated into many languages like Arabic, Hindi, English and Sindhi etc. His books are unparalleled in modernity and literary style in Urdu prose, Islamic teachings in his works. Ishq Rasool is prominent in Islamic civilization and Sufism. Deeply immersed in the love of Rasool, he wrote the book Aqa on the Zaat Mubaraka of Rasoolullah. In it, the blessings of the Holy Prophet (peace and blessings of Allah be upon him) have been described in a very beautiful way and in very touching words

A Researcher by Vocation, a Science Manager by Duty: to the 50th Anniversary of A.Yu. Samarin

This article charts the career of Alexander Yuryevich Samarin, Deputy Director General for Scientific and Publishing Activities at the Russian State Library (RSL), Doctor of Historical Sciences, and the Honoured Worker of Culture of the Russian Federation. It details his professional journey, starting from his studies at the V.I. Lenin Moscow State Pedagogical University (1990—1995), and concludes with his current position. A.Yu. Samarin has authored more than 560 scientific papers and has received over ten state and public awards. As a scientist, A.Yu. Samarin is recognized for his meticulous study of sources related to his research topics, and for his deep interest in the individuals who have made significant contributions to history. His most prominent administrative achievements include streamlining the operations of the RSL Research Department of Rare Books (Book Museum); his advocacy for establishing a legal framework for book monuments; his efforts to restore library science, bibliography, and book science as part of the Nomenclature of scientific specialties; holding the International Scientific Conference “Library Science in the 21st Century: Content, Organisation, Digitalisation, and Scientometrics” (2021). Finally, the article highlights the release of two editions of a joint monograph titled “Scientific Research in Libraries: Topics, Organisation, and Presentation of Results” in 2021 and 2023.

Mitigating Weight Stigma in Long-Term Care With Trauma-Informed Principles

Mitigating Weight Stigma in Long-Term Care With Trauma-Informed Principles

Histopathologic Validation of Stress T1 Mapping in Myocardial Ischemia: Another Step toward Clinical Translation?

Histopathologic Validation of Stress T1 Mapping in Myocardial Ischemia: Another Step toward Clinical Translation?

Ion Jarcuțchi (1948–2014): historian of the Modern Age and chronicler of science

Ion Jarcuțchi (1948–2014), historian, specialist in the field of national history of the Modern Age, history of science in Bessarabia/Moldovan SSR/Republic of Moldova, PhD in history (1984), research lecturer (1995). Author of about 70 scientific works, including four monographic studies. Between years 1977 and 1995 he worked at the Institute of History of the Academy of Sciences of the Moldovan SSR/Moldova as a senior laboratory assistant, trainee research scientist, senior research scientist, head of sector. He held scientific and managerial positions in the Presidium (1995–2004), the Supreme Council for Science and Technological Development (2004) and the Section of Humanities and Arts of the Academy of Sciences of Moldova (2005–2009). Acting Director (2009–2010), Acting Deputy Director (2010), Head of the Centre for Historical Studies (2011–2013) of the Institute of History, State and Law of the Academy of Sciences of Moldova. Between years 2013 and 2014, he worked in the Institute of Encyclopedic Studies of the Academy of Sciences of Moldova.

Retrieve, Summarize, and Verify: How Will ChatGPT Affect Information Seeking from the Medical Literature?

1National Center for Biotechnology Information (NCBI), National Library of Medicine (NLM), National Institutes of Health (NIH), Bethesda, MD, USA aCorresponding author: Zhiyong Lu, Ph.D., FACMI, Senior Investigator & Deputy Director for Literature Search, National Center for Biotechnology Information (NCBI), National Library of Medicine, National Institutes of Health, 8600 Rockville Pike, Bethesda, MD 20894, USA, Tel: 301-594-7089, E-mail: [email protected]

The first experience in developing a training methodology for the hospital-based health technology assessment in Ukraine

Health technology assessment in the world is increasingly conducted at the hospital level, where the costs, impacts and benefits of health technology can be directly assessed in a specific hospital. One of the urgent issues is the preparation of qualified hospital staff for the implementation of hospital-based HTA. Aim. Develop and conduct the first training on hospital-based health technology assessment for hospital stakeholders of Ukraine. Materials and methods. DACEHTA (англ. Danish Centre for Evaluation and Health Technology assessment) and AdHopHTA (англ. Adopting hospital-based Health Technology Assessment) guidelines were included into the analysis. The methods of content analysis, systematization and data generalization were used. Results. The first training on hospital-based HTA was conducted in the Regional Clinical Hospital named after O. O. Gerbachevsky of the Zhytomyr Regional Council. 9 hospital stakeholders were identified by preliminary semi-structured interview: the medical director of therapy, the medical director of surgery, the deputy director of economic, the head of the monitoring department, the representative of the information and statistics department, representatives of two clinical departments, of laboratory department and department of functional diagnostics. The curriculum was build taking into account he basic HB-HTA skills needed for hospital specialist should possess and included 8 blocks, each lasting 1.5 hours. Each block consisted of both theoretical and practical components and finished with homework, which was discussed at the beginning of the next block. This approach enabled the participants to better assimilate the presented information and carefully complete the homework of each block. Conclusions. The participants of the training noted that the use of hospital-based HTA is the most relevant issue today. Making management decisions based on HB-HTA will allow a more optimized hospital budget usage. At the same time, the participants emphasized the importance of the work of a cross-functional team in conducting HB-HTA with the mandatory involvement of hospital economists. Based on training participants and HTA international experts feedback, a two-week post-graduated course "Hospital-based HTA is a practical tool for making scientifically based decisions at the hospital level" was developed and approved in the NMU named after O.O. Bogomolets.

Nina Petrovna Toropova

Nina Petrovna Toropova is a prominent Russian scientist, Doctor of Medical Sciences, Professor, Honored Doctor of the Russian Federation, founder of the Ural Scientific School of Pediatric Dermatology, from 1987 to 2001 - Chief Freelance Pediatric Dermatovenerologist of the Ministry of Health of the Russian Federation, from 1982 to 2009 - Chief Freelance Pediatric dermatovenereologist of the Ministry of Health of the Sverdlovsk region. For many years N.P. Toropova was the Deputy Director for Research at the Ural Research Institute of Dermatovenereology and Immunopathology; from 1993 to 2001 - Director of the Sverdlovsk Scientific and Practical Center for Pediatric Dermatology and Venereology.