Complex Defects Research Articles

Metallocorroles as bifunctional electrocatalysts for water-splitting: A theoretical investigation

Designing efficient electrocatalysts for the oxygen evolution reaction (OER) and hydrogen evolution reaction (HER) is an important step of the water-splitting procedure, due to the expensive electrocatalysts and the energy loss because of overpotentials. Accordingly, in the present study and based on the newly synthesized copper-corrole complexes, several metallocorroles that can be used as electrocatalysts in water-splitting reaction were theoretically designed. The main objective of the present study is to investigate the electrocatalytic behavior of various metallocorroles toward OER at the anode as well as HER at the cathode. So, our focus will be on the corrole substrates incorporating Cr, Mn, Fe, Co, Ni, and Cu single atoms, nitrogen removal defective complexes, and Cl-functionalized corroles to explore the effect of structural modifications on the catalytic activity of metallocorroles. We found that the Ni- and Cr-corrole are encouraging catalysts for the OER and HER, respectively, outperforming the synthesized copper-based substrate and other designed metallocorroles with low overpotentials (ƞOER=0.68 V and ƞHER=0.10 V). The obtained Gibbs free energies confirm the feasibility of OER on a Ni single atom and HER on a Cr single atom of metallocorroles. The Volcano diagrams also reveal that the metallocorroles with better oxygen and hydrogen desorption correspond to the Ni- and Cr-corrole substrates, respectively. Generally, results show that our designed metallocorroles can be considered competent catalysts for water-splitting reactions.

Biological conduits based on spider silk for reconstruction of extended nerve defects.

The availability of appropriate conduits remains an obstacle for successful reconstruction of long-distance nerve defects. In previous sheep trials, we were able to bridge 6 cm nerve gaps with nerve conduits based on spider silk fibers with full functional outcomes. Here, we describe the first application of spider silk for nerve repair inhumans. Four patients with extended nerve defects (>20 cm) underwent nerve reconstruction by interposition of conduits that were composed of spider silk fibers contained in autologous veins. The longitudinal luminal fibers (approx.2500 fibers per graft) consisted of drag line silkfrom Trichonephila spiders. All patients were evaluated between 2and 10 years postreconstruction, clinically, and byneurography. In all patients, primary wound healing and no adverse reactions to the implanted spider silk material wereobserved. Patients regained the following relevant functions: protective sensibility, full flexor function with near-normal grasp and powerful function after microvascular gracilis muscle transfer, and key grip function and gross finger flexion after additional tenodesis. One patient with sciatic nerve reconstruction developed protective sensibility of the lower leg, foot, and gait, enabling normal walking and jogging. No neuroma formation or neuropathic or chronic pain occurred in any of the patients. For patients with extended peripheral nerve defects in the extremities, use of conduits based on spider silk fibers offers the possibility of restoring sensory function and protection from neuroma. This kind of nerve bridges provides new perspectives for the reconstruction of complex and long-distance nerve defects.

Intellectual Disabilities and Neurocognitive Impairment in Adult Patients with Inherited Metabolic Diseases: A UK Single Centre Experience.

Inherited metabolic diseases (IMDs) are a group of heterogeneous genetic disorders resulting in substrate accumulation, energy deficiency, or complex molecular defects due to the failure of specific molecules to act as enzymes, cofactors, transporters, or receptors in specific metabolic pathways. The pathophysiological changes seen in IMDs are sometimes associated with intellectual disability (ID) or neurocognitive decline, necessitating multidisciplinary input. We here describe our experience at one tertiary metabolic centre in the UK. We reviewed the case prevalence and existing service provision in one adult IMD service covering a multi-ethnic population of 10 million in North England. In our cohort of 2268 IMD patients, 1598 patients had general metabolic conditions (70.5%), and 670 had lysosomal storage disease/disorders (LSD)s (29.5%). The overall prevalence of ID and neurocognitive decline was found to be 15.7% (n = 357), with patients with LSDs accounting for 23.5% (n = 84) of affected patients. Given the prevalence of ID in adults with IMDs, access to multidisciplinary input from neuropsychology and neuropsychiatry services is important. Education of healthcare professionals to diagnose IMDs in patients with ID, in addition to neurocognitive and neuropsychiatric presentations, will avoid missed diagnoses of IMD and will have a positive effect on patient outcomes.

Secondary defect coverage and functional reconstruction

Secondary reconstruction in trauma surgery is crucial for restoring both functional and esthetic results in patients with complex defects. Established reconstructive techniques in plastic surgery offer awide range of options for an effective treatment. This applies not only to covering large defects with free flaps but especially also for the functional reconstruction of bony, neural and musculotendinous impairments. Advances in the fields of microsurgery and 3D printing show innovative approaches to further improve the therapeutic options. Amultidisciplinary approach, requiring close collaboration between trauma and plastic surgeons, is necessary to optimize treatment plans and outcomes. The effective management of complications and qualified postoperative care are essential for the success of reconstructive measures.

DFT study of the role and possible contribution of defects to lithium metasilicate [formula omitted] luminescence

Lithium metasilicate (Li2SiO3) has recently been shown to display outstanding stimulated luminescence properties, which are governed by defects and/or impurities. Here, the possible contribution and character of native point and complex defects to stimulated luminescence of lithium metasilicate have been investigated employing calculations based on the density functional theory (DFT). Under high concentrations of acceptor defects, isolated lithium interstitials were found to be the defects with the lowest formation energy (0.41 eV) but it is shown that they cannot contribute to luminescence. On the other hand, Oi−2 are the most favorable and stable defects under high concentrations of donor defects. F-centers and oxygen peroxides were identified as first- and second-order processes of point defects, which would explain experimental observations in the literature. Bridging oxygen vacancies were shown to introduce shallow electron traps able to trap up to four electrons. On the contrary, non-bridging oxygen vacancies lead to the formation of deep color centers with the capability of trapping up to two carriers/center, which could be the final state for the radiative process of luminescence. These results provide guidance for the interpretation of experimental measurements of luminescence.

PICKLE and HISTONE DEACETYLASE6 coordinately regulate genes and transposable elements in Arabidopsis.

Chromatin dynamics play essential roles in transcriptional regulation. The chromodomain helicase DNA-binding domain 3 chromatin remodeler PICKLE (PKL) and HISTONE DEACETYLASE6 (HDA6) are required for transcriptional gene silencing, but their coordinated function in gene repression requires further study. Through a genetic suppressor screen, we found that a point mutation at PKL could partially restore the developmental defects of a weak Polycomb repressive complex 1 (PRC1) mutant (ring1a-2 ring1b-3), in which RING1A expression is suppressed by a T-DNA insertion at the promoter. Compared to ring1a-2 ring1b-3, the expression of RING1A is increased, nucleosome occupancy is reduced, and the histone 3 lysine 9 acetylation (H3K9ac) level is increased at the RING1A locus in the pkl ring1a-2 ring1b-3 triple mutant. HDA6 interacts with PKL and represses RING1A expression similarly to PKL genetically and molecularly in the ring1a-2 ring1b-3 background. Furthermore, we show that PKL and HDA6 suppress the expression of a set of genes and transposable elements (TEs) by increasing nucleosome density and reducing H3K9ac. Genome-wide analysis indicated they possibly coordinately maintain DNA methylation as well. Our findings suggest that PKL and HDA6 function together to reduce H3K9ac and increase nucleosome occupancy, thereby facilitating gene/TE regulation in Arabidopsis (Arabidopsis thaliana).

Fabrication Strategies for Bioceramic Scaffolds in Bone Tissue Engineering with Generative Design Applications.

The aim of this study is to provide an overview of the current state-of-the-art in the fabrication of bioceramic scaffolds for bone tissue engineering, with an emphasis on the use of three-dimensional (3D) technologies coupled with generative design principles. The field of modern medicine has witnessed remarkable advancements and continuous innovation in recent decades, driven by a relentless desire to improve patient outcomes and quality of life. Central to this progress is the field of tissue engineering, which holds immense promise for regenerative medicine applications. Scaffolds are integral to tissue engineering and serve as 3D frameworks that support cell attachment, proliferation, and differentiation. A wide array of materials has been explored for the fabrication of scaffolds, including bioceramics (i.e., hydroxyapatite, beta-tricalcium phosphate, bioglasses) and bioceramic-polymer composites, each offering unique properties and functionalities tailored to specific applications. Several fabrication methods, such as thermal-induced phase separation, electrospinning, freeze-drying, gas foaming, particle leaching/solvent casting, fused deposition modeling, 3D printing, stereolithography and selective laser sintering, will be introduced and thoroughly analyzed and discussed from the point of view of their unique characteristics, which have proven invaluable for obtaining bioceramic scaffolds. Moreover, by highlighting the important role of generative design in scaffold optimization, this review seeks to pave the way for the development of innovative strategies and personalized solutions to address significant gaps in the current literature, mainly related to complex bone defects in bone tissue engineering.

Complex defect formation in Fe doped γ-CuI: Enhancement of thermoelectric properties via band engineering

The doping effect of Fe atoms on CuI, a potential candidate for room temperature thermoelectric materials, was investigated due to the lack of studies for the aspect of band engineering. The addition of Fe atoms was observed to enhance the p-type performance of CuI, although Fe is more suitable as a donor material. Through Mossbauer spectroscopy and Density Functional Theory (DFT) calculations, it was determined that only about 5 % of the added Fe atoms simply substitute Cu sites, while most Fe atoms occupy interstitial sites, acting as defects and promoting Cu vacancies. Despite the trace amount of Fe only contribute to magnetic properties, it was found that multiple defects and deformation in the electronic band structure caused the effective mass to nearly double. As a result, electrical conductivity increased by an order of magnitude, while the decrease in the Seebeck coefficient was less than half, demonstrating a violation of the Pisarenko relation. Additionally, the incorporation of Fe atoms induced nano structuring behavior, increasing boundary scattering in CuI and significantly reducing thermal conductivity. Fe could be suggested as a suitable dopant for the "phonon-glass-electron-crystal" strategy.

Effect of HPHT technology and Se doping on thermoelectric properties of In filled Fe doped CoSb3 materials

Skutterudite (CoSb3) is a kind of promising environment-friendly medium-temperature thermoelectric material. Indium-filled CoSb3 has been widely studied, but its bipolar effect, which is commonly generated between 600 and 700 K, seriously hinders the increase of Seebeck coefficient and zT value. The zT value not only directly reflects the overall thermoelectric performance of the material, but also reflects the thermoelectric conversion efficiency of the device. In this work, In filled and Fe, Se double doped CoSb3 materials were successfully prepared by high-temperature and high-pressure synthesis method (HPHT), with a significant shorten synthesis time of 30 mins for each sample. This research has shown that after Se doping via HPHT synthesis method, the bipolar effect of In-filled CoSb3 was significantly suppressed, thus the temperature limitations of electrical transport performance has been overcome. Through the further microstructure analysis, it was found that the crystal structure of sample In0.5Fe0.01Co3.99Sb11.91Se0.09 has the characteristics of multiple grain sizes and complex defect types. And these two microscopic morphological characteristics resulted in the sample obtaining a minimum lattice thermal conductivity of 0.94 Wm−1K−1 at a test temperature of 773.15 K. Through synergistic optimization of synthesis methods and element substitution, the maximum zT value of 1.21 of the sample In0.5Fe0.01Co3.99Sb11.91Se0.09 has been found at 773.15 K.

Improved YOLOv5 Network for Aviation Plug Defect Detection

Ensuring the integrity of aviation plug components is crucial for maintaining the safety and functionality of the aerospace industry. Traditional methods for detecting surface defects often show low detection probabilities, highlighting the need for more advanced automated detection systems. This paper enhances the YOLOv5 model by integrating the Generalized Efficient Layer Aggregation Network (GELAN), which optimizes feature aggregation and boosts model robustness, replacing the conventional Convolutional Block Attention Module (CBAM). The upgraded YOLOv5 architecture, incorporating GELAN, effectively aggregates multi-scale and multi-layer features, thus preserving essential information across the network’s depth. This capability is vital for maintaining high-fidelity feature representations, critical for detecting minute and complex defects. Additionally, the Focal EIOU loss function effectively tackles class imbalance and concentrates the model’s attention on difficult detection areas, thus significantly improving its sensitivity and overall accuracy in identifying defects. Replacing the traditional coupled head with a lightweight decoupled head improves the separation of localization and classification tasks, enhancing both accuracy and convergence speed. The lightweight decoupled head also reduces computational load without compromising detection efficiency. Experimental results demonstrate that the enhanced YOLOv5 architecture significantly improves detection probability, achieving a detection rate of 78.5%. This improvement occurs with only a minor increase in inference time per image, underscoring the efficiency of the proposed model. The optimized YOLOv5 model with GELAN proves highly effective, offering significant benefits for the precision and reliability required in aviation component inspections.

Microbiological challenges in the treatment of war injuries

The treatment of war injuries represents a continuing and recurrent challenge in modern reconstructive surgery. Previously, tumor resections and sepsis-related resections were mainly responsible for lengthy bone defects in Germany. In recent years another picture has increasingly emerged, particularly caused by the medical support of Ukraine. Aspects of military surgery are also becoming more important in civil hospitals, especially in the treatment of gunshot and explosion injuries. In Germany, war injuries are currently secondarily treated, as the distribution of patients is carried out according to the cloverleaf principle, weeks or months after the occurrence of the primary injury. In addition to complex bone and soft tissue defects of the extremities following such injuries, which often affect neural and vascular structures, reconstruction is often complicated by an increasing spectrum of multidrug-resistant pathogens. The definition of microbiological terms, such as contamination, colonization, critical colonization, local and systemic infections are important in the clinical routine in order to initiate a targeted treatment, especially in treatment with antibiotics. Wound swabs for determination of the spectrum of pathogens and the optimal testing of resistance are important for selecting the appropriate antibiotic agents. The concept of antibiotic stewardship (ABS) is established in many hospitals to improve the quality of antibiotic treatment and to minimize the formation of resistance. The selection of the method of reconstruction depends on the condition of the patient, the overall clinical constellation and the function to be expected after completion of treatment. The treatment of injuries due to violence and terrorism necessitates clear concepts and an interdisciplinary approach, especially with respect to microbiological challenges and increasing resistance situations.

TFL Perforator Flap Complementing and Completing the ALT-AMT Flap Axis.

Background Anterolateral thigh (ALT) flap is the most common soft tissue flap used for microvascular reconstruction of head and neck. Its harvest is associated with some unpredictability due to variability in perforator characteristics, injury or unfavorable configuration for complex defects. Anteromedial thigh (AMT) flap is an option, but the low incidence and thickness restrict its utility. Tensor fascia lata (TFL) perforator (TFLP) flap is an excellent option to complement ALT. Its perforator is consistent, robust, in vicinity, and lends itself with the ALT perforator. Methods This study was an analysis of 29 cases with a free flap for head neck reconstruction with an element of TFLP flap from July 2017 to May 2021. Results All cases were primarily planned for an ALT reconstruction. There was absence of the ALT perforator in 16 cases but a sizable TFL perforator was available. In 13 cases, the complex defect warranted use of both ALT plus TFL in a conjoint (5), chimeric (5), and multiple (3) free flaps manner. Most common perforator location was septocutaneous between the TFL and gluteus medius. There was complete flap loss in two cases and partial necrosis in two. No adjuvant therapy was delayed. Conclusion TFLP can reliably complement the ALT/AMT axis. Chimeric ALT-TFL can be harvested for large, complex, multicomponent, and multidimensional defects.

Distally based peroneus brevis flap: Reconstruction of complex soft-tissue defects with bony infection of the lateral malleolus

BackgroundManaging wounds of the lateral malleolus is challenging owing to limited nearby tissues and possibly injured or inadequate vessels for free flaps, especially in case of underlying infections. Moreover, free flaps require specialized skills and are not suitable for every patient. Therefore, identifying reliable local alternatives is crucial. This retrospective study investigated the efficacy and safety of the distally based peroneus brevis muscle flap in treating complex and infected soft-tissue defects of the lateral malleolus. Materials and methodsA retrospective medical chart review of all patients who underwent a distally based peroneus brevis muscle flap reconstruction in the context of an infected lateral malleolus defect at Geneva University Hospitals between October 2020 and January 2024 was performed. ResultsTen patients underwent lateral malleolus reconstruction using a distally based peroneus brevis muscle flap primarily to address post-traumatic infections. Flap coverage was performed within 4 weeks of infection onset for post-traumatic cases, alongside antibiotic treatment. The defects were moderate in size, with a median width of 2.5 cm and length of 5.5 cm. There were no complete or partial flap failures. All patients regained the ability to walk within 5 days after surgery. ConclusionsThe distally based peroneus brevis muscle flap was efficient in managing complex and infected soft-tissue defects of the lateral malleolus, with control of infection in all patients and minimal donor-site morbidity.

Diffusion‐induced phase separation 3D printed scaffolds for dynamic tissue repair

AbstractMany hydrogen‐bonded cross‐linked hydrogels possess unique properties, but their limited processability hinders their potential applications. By incorporating a hydrogen bond dissociator (HBD) into these hydrogels, we developed injectable 3D printing inks termed diffusion‐induced phase separation (DIPS) 3D printing inks. Upon extrusion into water and subsequent diffusion of HBD, these ink cure rapidly. The DIPS‐printed scaffold retained most of the original hydrogel properties due to the regeneration of hydrogen bonds. Additionally, the reversible nature of hydrogen bonds provides DIPS 3D‐printed scaffolds with exceptional recycling and reprinting capabilities, resulting in a reduction in the waste of valuable raw ink materials or additives. Postprocessing introduces new crosslinking methods that modulate the mechanical properties and degradation characteristics of DIPS scaffolds over a broad range. Based on its suitable mechanical properties and bioactivity, we successfully repaired and functionally reconstructed a complex defect in penile erectile tissue using the DIPS scaffold in a rabbit model. In summary, this approach is relevant for various hydrogen‐bonded cross‐linked hydrogels that offer mild printing conditions and enable the incorporation of bioactive agents. They can be used as scaffolds for dynamic tissue reconstruction, wearable devices, or soft robots.

The Annealing Kinetics of Defects in CVD Diamond Irradiated by Xe Ions

The radiation-induced optical absorption at 1.5–5.5 eV (up to the beginning of fundamental absorption) has been analyzed in CVD diamond disks exposed to 231-MeV 132Xe ions with four fluences from 1012 to 3.8 × 1013 cm−2. The 5 mm diameter samples (thickness 0.4 mm) were prepared by Diamond Materials, Freiburg (Germany); the average grain size at growth site was around 80 μm; and the range of xenon ions was R = 11.5 μm. The intensity of several bands grows with ion fluence, thus confirming the radiation-induced origin of the defects responsible for these bands. The recovery of radiation damage has been investigated via isochronal (stepwise) thermal annealing procedure up to 650 °C, while all spectra were measured at room temperature. Based on these spectra, the annealing kinetics of several defects, in particular carbon vacancies (GR1 centers with a broad band ~2 eV) and complementary C-interstitial-related defects (~4 eV), as well as impurity-related complex defects (narrow bands around 2.5 eV) have been constructed. The experimental kinetics have also been analyzed in terms of the diffusion-controlled bimolecular reactions. The migration energies of tentatively interstitial atoms (mobile components in recombination process) are obtained, and their dependence on the irradiation fluences is discussed.

Challenge of limb care after violence and war with aspecial focus on imaging procedures

Injury patterns in the area of the extremities following violence and war harbor many special features and require special attention. Destructive and complex defect injuries are often present, which necessitate elaborate and special reconstruction approaches, predominantly as part of astaged and multistaged procedure. In this context, special attention must be paid to the diagnostic options as an essential aspect, as aclear diagnosis means that targeted treatment steps can be planned and implemented. The authors' experience in this field from military operations in Afghanistan, Iraq, the Republic of Mali, Kosovo and Georgia, as well as the core content of the Terror and Disaster Surgical Care (TDSC®) course on this topic, have been contextualized and incorporated. In addition, aspects of interdisciplinary cooperation with radiological and, in particular, nuclear medicine disciplines are taken into account in the daily routine. Extremity injuries in the context of violence and war are accompanied by complex bone and surrounding soft tissue defects due to the high energy impact. The principles of reconstruction familiar from everyday life can only be transferred one-to-one to alimited extent. The treatment pathways are often very long and complex and the questions of infection and tissue vitality must be answered again and again in stages. Interdisciplinary collaboration with the disciplines specialized in imaging procedures, particularly in the field of nuclear medicine, is one of the key building blocks for a successful treatment pathway.

Hair Transplantation on the Baldness Region with Free Latissimus Dorsi Flap for Scalp Reconstruction: A Case Report

AbstractScalp reconstruction, particularly with complex defects and infection risks, often favors microvascular free flaps. However, this method can result in unavoidable alopecia and undesirable aesthetics. This report describes a novel case where hair transplantation via follicular unit extraction (FUE) was applied to a free myocutaneous flap. A 44-year-old woman with Moyamoya disease suffered intracerebral hemorrhage a decade ago. Craniotomies and autologous bone cranioplasties led to wound dehiscence, with subsequent failed local flaps and skin grafts, and identification of a methicillin-resistant Staphylococcus aureus infection. The final scalp defect, measuring 13 × 9 cm, was reconstructed using a free myocutaneous latissimus dorsi flap. Nine years post-surgery, a 1,500-unit FUE hair transplantation procedure was conducted. The transplanted hair exhibited robust survival with adequate blood supply, achieving a satisfactory 80 to 85% survival rate at 12 months. This resulted in a notable improvement in the patient's external alopecia, with reported high levels of satisfaction. Free flaps offer a valuable method for scalp defect reconstruction; however, they may not ensure optimal aesthetic satisfaction due to alopecia. Nonetheless, successful FUE hair transplantation on a myocutaneous free flap can yield satisfactory aesthetic results.

The use of peroneus brevis in lower limb reconstruction—What we have learned from 49 cases

IntroductionThere are many suitable techniques for the treatment of soft tissue defects of the lower limb. Older subjects often with multiple comorbidities, presenting with a laterally located and complex defect, can be challenging to treat. This cohort are often unsuited to long procedures or multi-stage reconstruction and so one is faced with a paucity of options. In such instances, we use the peroneus brevis (PB) muscle flap as a single stage procedure. MethodsWe performed a retrospective study evaluating the use of PB flaps in lower limb injury. Subjects were collated using a database and multiple variables were assessed including: patient demographics, comorbidities, defect size, peri-operative timings, time in theatre, use of inotropes / blood transfusion, mean hospital stay, patient morbidity / mortality, flap survival. ResultsDuring 2015–2023, 49 patients underwent lower limb reconstruction using PB muscle flaps. 42 cases involved PB and skin graft alone whilst seven were more complex requiring additional local and free tissue techniques. The most common indication (n = 28) was infection after closed fracture fixation, followed by open trauma (n = 21).Median patient age was 59 (20–93 years), and ASA grade 3. Median defect size was 4 × 7 cm (2–18 cm) and time from admission to definitive closure 4 days (0–21 days) with median time in theatre 120 min (45–520 min). 17 patients required inotropes and 13 had blood transfusion. Median length of hospital stay was 12 days (0–58 days), one patient (aged 90) died. 100 % of flaps survived and median Enneking score was 65. Heterotopic ossification was not identified in the post-operative imaging within the first year. DiscussionOur experience highlights the benefits and risks of using the PB flap and advocates it as a reliable, cost-effective, 1-stage technique for reconstructing small lateral defects in the distal third of the lower limb.

Machine-learning structural reconstructions for accelerated point defect calculations

Defects dictate the properties of many functional materials. To understand the behaviour of defects and their impact on physical properties, it is necessary to identify the most stable defect geometries. However, global structure searching is computationally challenging for high-throughput defect studies or materials with complex defect landscapes, like alloys or disordered solids. Here, we tackle this limitation by harnessing a machine-learning surrogate model to qualitatively explore the structural landscape of neutral point defects. By learning defect motifs in a family of related metal chalcogenide and mixed anion crystals, the model successfully predicts favourable reconstructions for unseen defects in unseen compositions for 90% of cases, thereby reducing the number of first-principles calculations by 73%. Using CdSexTe1−x alloys as an exemplar, we train a model on the end member compositions and apply it to find the stable geometries of all inequivalent vacancies for a range of mixing concentrations, thus enabling more accurate and faster defect studies for configurationally complex systems.

WSS-YOLO: An improved industrial defect detection network for steel surface defects

Surface defects in steel manufacturing can compromise product quality and safety. Detecting these diverse and complex defects under industrial conditions is challenging. This paper proposes WSS-YOLO, a YOLOv8-based model, for accurate defect detection on industrial steel. Firstly, the dynamic non-monotonic focusing mechanism based on WIoU loss was employed to focus on anchor boxes with ordinary quality, thereby improving the overall performance of the detector. Secondly, the C2f-DSC module based on dynamic snake convolution is designed to enable the model to adaptively adjust the receptive field. Finally, GSConv and VOV-GSCSP modules are introduced into the neck network to reduce the computational complexity and parameter quantity while ensuring the accuracy of the model. This paper conducts extensive experiments on the public datasets NEU-DET and GC10-DET, achieving mAP of 82.3% and 72.0%, respectively, outperforming other excellent models. Moreover, the effectiveness of the proposed method in industrial defect detection is also validated.