Deuterium-tritium (D-T) fusion is a key to generating safe, clean, and limitless energy on Earth in future fusion power plants. Its understanding at low collision energies is incomplete, as D-T fusion is a quantum tunneling process affected by resonances whose origin is linked to properties of not fully understood nuclear forces. Simplified quantum dynamical calculations of laser-assisted D-T fusion are presented, suggesting that laser-nucleus interaction can enhance the average D-T fusion probability by 7–70% at deep subbarrier energies using laser fields of intensity 1027–1029 Wcm−2 and a photon energy of 1 eV. Published by the American Physical Society 2024