Current Version Research Articles

Microfragmented Fat and Biphasic Calcium Phosphates for Alveolar Cleft Repair: Protocol for a Prospective, Nonblinded, First-in-Human Clinical Study.

Biphasic calcium phosphates (BCP) may serve as off-the-shelf alternatives for iliac crest-derived autologous bone in alveolar cleft reconstructions. To add osteoinductivity to the osteoconductive BCPs to achieve similar regenerative capacity as autologous bone, a locally harvested buccal fat pad will be mechanically fractionated to generate microfragmented fat (MFAT), which has been shown to have high regenerative capacity due to high pericyte and mesenchymal stem cell content and a preserved perivascular niche. Our primary objectives will be to assess the feasibility and safety of the BCP-MFAT combination. The secondary objective will be efficacy, which will be evaluated using radiographic imaging and histological and histomorphometric evaluation of biopsies taken 6 months postoperatively, concomitant with dental implant placement. Eight patients with alveolar cleft (≥15 years) will be included in this prospective, nonblinded, first-in-human clinical study. MFAT will be prepared intraoperatively from the patient's own buccal fat pad. Regular blood tests and physical examinations will be conducted, and any adverse events (AEs) or serious EAs (SAEs) will be meticulously recorded. Radiographic imaging will be performed prior to surgery and at regular intervals after reconstruction of the alveolar cleft with the BCP-MFAT combination. Biopsies obtained after 6 months with a trephine drill used to prepare the implantation site will be assessed with histological and histomorphometric analyses after methylmethacrylate embedding and sectioning. The primary outcome parameter will be safety after 6 months' follow-up, as monitored closely using possible occurrences of SAEs based on radiographic imaging, blood tests, and physical examinations. For efficacy, radiographic imaging will be used for clinical grading of the bone construct using the Bergland scale. In addition, bone parameters such as bone volume, osteoid volume, graft volume, and number of osteoclasts will be histomorphometrically quantified. Recruitment started in November 2019, and the trial is currently in the follow-up stage. This protocol's current version is 1.0, dated September 15, 2019. In this first-in-human study, not only safety but also the histologically and radiographically assessed regenerative potential of the BCP-MFAT combination will be evaluated in an alveolar cleft model. When an SAE occurs, it will be concluded that the BCP-MFAT combination is not yet safe in the current setting. Regarding AEs, if they do not occur at a higher frequency than that in patients treated with standard care (autologous bone) or can be resolved by noninvasive conventional methods (eg, with analgesics or antibiotics), the BCP-MFAT combination will be considered safe. In all other cases, the BCP-MFAT combination will not yet be considered safe. Indonesia Clinical Trial Registry INA-EW74C1N; https://tinyurl.com/28tnrr64. DERR1-10.2196/42371.

GLOBGM v1.0: a parallel implementation of a 30 arcsec PCR-GLOBWB-MODFLOW global-scale groundwater model

Abstract. We discuss the various performance aspects of parallelizing our transient global-scale groundwater model at 30′′ resolution (30 arcsec; ∼ 1 km at the Equator) on large distributed memory parallel clusters. This model, referred to as GLOBGM, is the successor of our 5′ (5 arcmin; ∼ 10 km at the Equator) PCR-GLOBWB 2 (PCRaster Global Water Balance model) groundwater model, based on MODFLOW having two model layers. The current version of GLOBGM (v1.0) used in this study also has two model layers, is uncalibrated, and uses available 30′′ PCR-GLOBWB data. Increasing the model resolution from 5′ to 30′′ creates challenges, including increased runtime, memory usage, and data storage that exceed the capacity of a single computer. We show that our parallelization tackles these problems with relatively low parallel hardware requirements to meet the needs of users or modelers who do not have exclusive access to hundreds or thousands of nodes within a supercomputer. For our simulation, we use unstructured grids and a prototype version of MODFLOW 6 that we have parallelized using the message-passing interface. We construct independent unstructured grids with a total of 278 million active cells to cancel all redundant sea and land cells, while satisfying all necessary boundary conditions, and distribute them over three continental-scale groundwater models (168 million – Afro–Eurasia; 77 million – the Americas; 16 million – Australia) and one remaining model for the smaller islands (17 million). Each of the four groundwater models is partitioned into multiple non-overlapping submodels that are tightly coupled within the MODFLOW linear solver, where each submodel is uniquely assigned to one processor core, and associated submodel data are written in parallel during the pre-processing, using data tiles. For balancing the parallel workload in advance, we apply the widely used METIS graph partitioner in two ways: it is straightforwardly applied to all (lateral) model grid cells, and it is applied in an area-based manner to HydroBASINS catchments that are assigned to submodels for pre-sorting to a future coupling with surface water. We consider an experiment for simulating the years 1958–2015 with daily time steps and monthly input, including a 20-year spin-up, on the Dutch national supercomputer Snellius. Given that the serial simulation would require ∼ 4.5 months of runtime, we set a hypothetical target of a maximum of 16 h of simulation runtime. We show that 12 nodes (32 cores per node; 384 cores in total) are sufficient to achieve this target, resulting in a speedup of 138 for the largest Afro–Eurasia model when using 7 nodes (224 cores) in parallel. A limited evaluation of the model output using the United States Geological Survey (USGS) National Water Information System (NWIS) head observations for the contiguous United States was conducted. This showed that increasing the resolution from 5′ to 30′′ results in a significant improvement with GLOBGM for the steady-state simulation when compared to the 5′ PCR-GLOBWB groundwater model. However, results for the transient simulation are quite similar, and there is much room for improvement. Monthly and multi-year total terrestrial water storage anomalies derived from the GLOBGM and PCR-GLOBWB models, however, compared favorably with observations from the GRACE satellite. For the next versions of GLOBGM, further improvements require a more detailed (hydro)geological schematization and better information on the locations, depths, and pumping rates of abstraction wells.

Memories of a Glorious or Difficult Past? Portugal, Padrão dos Descobrimentos and the (Lack of a) 21st Century Reckoning

AbstractThe purpose of this paper is to analyse a particularly influential case of memory continuity in Portugal, that ofPadrão dos Descobrimentos. Spaces of collective memory (such as public monuments) raise questions about what we celebrate, remember or rescue from oblivion, providing an opportunity to rethink the trauma. As such, care for public spaces is associated with ethical and cultural values. One of the difficulties with certain monuments has to do with the fact that they recall actions that today we see as traumatic acts. Thus, it is important to reflect on a critical use of memory. On August 8, 2021,Padrão dos Descobrimentoswas the subject of a graffiti. One of the sides of the monument could read: “Blindly sailing for money, humanity is drowning in a scarlet sea”. A great controversy immediately arose around the meaning of this gesture, as well as the role played by a monument that, after being temporarily built in 1940 for the Portuguese World Exhibition, was, in its current version, inaugurated in 1960, on the occasion of the fifth centenary of the death of Infante D. Henrique. This episode reignited a deeper cleavage around the uses of history and memory, the Portuguese colonial past, and the role of thePadrão dos Descobrimentosas an instrument for the reproduction of nationalism. In this sense, and with the authors proposing a new theoretical frame of reference based on the thought of Arendt and Ricoeur, its critical reading becomes relevant.

Demonstration of enhanced long-range cosmic time synchronization for wireless and secure dissemination of standard time

Accurate traceability of time is prerequisite to the proper functioning of many necessary aspects of our modern life including making financial transactions, managing automated technology and navigating the transport of goods and human beings. One of the most reliable international time references is the Coordinated Universal Time (UTC) that can be distributed wirelessly in principle. However, this wireless option is currently limited to GPS and other global navigation satellite systems. GPS signals are weak and easily affected by environmental conditions. Moreover, since GPS signals are unencrypted, the possibility of a signal spoofing attack remains a continuous threat. Prior works showed the potential of the alternative wireless time synchronization technique called Cosmic Time Synchronization (CTS), in which, clocks are located 50 m apart were wirelessly synchronized with a sub-microsecond level accuracy, and its operation time was limited to 20 min. However, for the actual implementation of CTS to real-life situations, these distance and stability values are not sufficient. In this study, we constructed a dedicated CTS facility and conducted a long-haul (180 m) CTS demonstration. As a result, it was verified that this long-range CTS is capable of maintaining stable sub-microsecond time synchronization for 3 days with a granularity of 148.8 ns (SD) and an offset of 22.97 ns. Since the current version of CTS can now operate over an area that has been enlarged by more than one order of magnitude, it is possible to utilize for more diverse applications, and the application to a banking synchronization system is proposed. As a case study, it is shown that CTS now has the capability to offer wireless time synchronization service to large clusters of financial firms in large cities. With its accurate time dissemination (the metrological traceability to UTC), its reasonable cost, and its hack-proof, stable design, this latest CTS model has the capacity to improve the accuracy of timing for a wide variety of sectors.

Developing a text-message library for tobacco prevention among adolescents: A qualitative study.

Communicating the risks associated with nicotine and tobacco use to adolescents can be challenging, especially with the current tobacco market's attempt to capture the attention of youths. Text message interventions have emerged to address the need to improve tobacco risk communication. This article informs the design of a message library for tobacco risk communication that is based on the transtheoretical model and addresses the risk of multiple tobacco products. We draw findings from this study from two phases. Phase 1 involved six remote focus group discussions (n = 25) and an in-depth interview, and Phase 2 involved online ideation sessions (n = 11) that led to the current version of the messages. We conducted the study within a larger project for the design and testing of a tobacco prevention program. With thematic analysis and the affinity mapping technique, two research team members identified repeated topics and relevant quotes to organize them into themes and subthemes. In Phase 1, thematic analysis revealed four major themes: 1) Adolescents' gap in tobacco knowledge, 2) Social influence and popularity, 3) Attitude toward marketing, and 4) Text message framing preferences. During Phase 2, participants generated 1-to-7 iterations of the original messages. Votings and discussions resulted in a library of 306 messages under 7 sections, categorized based on the processes of change from the transtheoretical model. The current study presents key insights crucial for developing and evaluating a library of tobacco prevention text messages that is scientifically valid and successfully resonates with today's adolescents. Our future plan is to go beyond this initial message development and vet the message library by adolescents and expert reviewers in tobacco risk communication. Future research may consider developing messages that are tailored based on gender, ethnicity, and other factors that are predictive of tobacco use.

Predictive factors for the treatment success of peri-implantitis: a protocol for a prospective cohort study

IntroductionPeri-implantitis, a common biological complication of dental implant, has attracted considerable attention due to its increasing prevalence and limited treatment efficacy. Previous studies have reported several risk factors associated with...

Balancing gain and dynamic range in a 25 µm pitch hybrid pixel detector

MÖNCH is a hybrid pixel detector featuring 25 µm pixel pitch and analogue readout for X-ray imaging at synchrotron radiation (SR) facilities. Sub-pixel spatial resolution has been demonstrated using charge sharing and interpolation algorithms. The current prototype version, MÖNCH0.4, features 19 different pixel architectures to assess the design choices and components for an optimised architecture to be used at SR facilities, and to explore the potential use of dynamic gain switching in fine pitch pixels for applications at X-ray free electron lasers (XFELs).Previous characterisation results of the pixel architectures without dynamic gain switching have shown noise levels as low as 21.7 e- r.m.s., which have now been pushed to sub-20 e- r.m.s at room temperature using standard 300 µm-thick silicon sensors. Achieving low noise values however requires high conversion gain and necessitates design choices such as the simplification of the pixel architecture (e.g. by limiting the available choice of in-pixel gains). These compromises ultimately restrain the available dynamic range and prevent the use of MÖNCH with low-gain avalanche diodes (LGADs) or high-Z sensors because of the large signals (internal amplification and high photon energies, respectively) and of large leakage currents.In this paper, we will introduce the MÖNCH project followed by a description of the current prototype along with characterisation results of the pixel architectures without dynamic gain switching for synchrotron applications with an emphasis on noise and dynamic range. These experimental results will be used to fine-tune the design of MÖNCH0.5 to validate the final pixel design. This small prototype should also include additional features from the continuous developments of the PSD detector group towards a full-scale 2 × 3 cm2 MÖNCH1.0.

Minimally invasive treatment of benign prostatic hyperplasia : The GermanS2eguideline 2023-part4

Lower urinary tract symptoms suggestive for benign prostatic obstruction (LUTS/BPO) are one of the most frequent diseases in men and can have asignificant impact on quality of life. Instrumental therapies are common, and many patients seek minimally invasive treatment options. Presentation and evidence-based evaluation of the minimally invasive therapy for benign prostatic syndrome. Summary and overview of chapters 11-13 on minimally invasive therapies for LUTS/BPO of the current long version of the German S2e guideline. In case of absolute indication for surgery or after unsatisfactory or undesired medical therapy, minimally invasive treatments such as UroLift® (Neotract Inc., Pleasanton, CA, USA), Rezῡm™ (Boston Scientific, Malborough, MA, USA), iTIND™ (Olympus America Inc., Westborough, MA, USA), and prostatic artery embolization (PAE) can be considered. These indirect/delayed ablative therapies offer lower morbidity and the possibility of performing them under local anesthesia, but they are inferior to direct ablative/resective techniques in terms of effectiveness and sustainability. The updated German S2e guideline summarizes evidence-based recommendations for new minimally invasive therapies for LUTS/BPO, which present alternative treatment options for selected patients.

Comparison of Laryngeal Palpatory Scale (LPS), With Surface Electromyographic Measures in Patients with Muscle Tension Dysphonia.

The aim of this study was to examine the laryngeal palpatory scale (LPS) to ascertain possible correlation with neck surface electromyography (sEMG). Two otolaryngologists and one certified speech-language pathologist assessed 21 participants (seven women and 14 men; with a mean age of 42.8 years; ranged: 21 to 70 years) with muscle tension dysphonia (MTD) diagnosed with the current version of the LPS rating system. Consequently, relationships between LPS and objective measures of sEMG were evaluated using Spearman's rank correlation coefficient (r). The results show that there was a low to moderate between correlations, (statistically positive and significant in 10 correlations among the examined items/states). In conclusion, low-moderate positive correlations between sEMG and LPS ratings were found with particular strength for LPS ratings of tightness and ratings made during dynamic tasks. Further investigations can provide useful evidence for researchers and clinicians to document treatment outcomes by using LPS and sEMG in patients with MTD and leading to the more standardized care and improved information about patient progress.

CatVolc: A new database of geochemical and geochronological data of volcanic-related materials from the Catalan Volcanic Zone (Spain)

The Catalan Volcanic Zone (CVZ) (NE Spain) consists of an intraplate alkaline volcanic zone associated with the opening of the Western Mediterranean and the development of the European Rift System. Volcanic activity in the CVZ started in the L'Empordà area (ca. > 12–8 Ma), extended to La Selva (7.9–1.7 Ma), and finally migrated to the Garrotxa Volcanic Field (< 0.7–0.01 Ma). Despite the scientific interest in the CVZ since the early 19th century, certain aspects remain poorly constrained. These include a full understanding of the spatial and temporal evolution of the magma plumbing system(s) and ascent mechanisms, as well as the chronology of volcanism across the CVZ. Addressing these unresolved questions requires geochemical, petrological, and geochronological data, which, in the case of the CVZ, are scattered and have never been integrated or analysed within a unified framework. Here, we present the CatVolc (Catalan Volcanism) database, which compiles available geochemical and geochronological data of volcanic-related materials from the CVZ. The current version of the database contains geochemical analyses from 405 rock samples (296 juvenile magmatic rocks -including lavas and pyroclasts- and 109 xenoliths), and radiometric/thermoluminescence dating data from 57 rocks (55 volcanogenic and two dykes), 4 paleosols samples developed between volcanic deposits and 1 sample from sediments. For each sample, the CatVolc database lists general information about the sampling site, sample lithology, whole-rock analyses (including major and trace elements), isotopic ratios, mineral chemistry, and radiometric/thermoluminescence dating information, if available. A preliminary analysis of the information contained in the CatVolc database highlights the critical limitations of the current state of knowledge and allows suggesting potential future directions for volcanic-driven investigations in the CVZ. Additionally, the results obtained validate the CatVolc database as a key tool for comprehending the spatial and temporal evolution of the magmatic system(s) and volcanic activity in the CVZ, particularly in the Garrotxa Volcanic Field. This aspect is critical for advancing in the assessment of the volcanic hazards in the region and for gaining a comprehensive understanding of future volcanic activity.

Applicability of Fine-Tuned ChatGPT to Automated Essay Scoring

ChatGPT, released in 2022, has garnered attention due to its adaptability through prompt engineering, enabling users to guide its responses. It is important to note that the extent to which users can modify ChatGPT remains limited, as its core embeddings stay unaltered through prompt engineering. Thus, this study aims to evaluate the effectiveness of ChatGPT and its fine-tuned model in essay evaluation compared to human raters. A total of 904 essays from the YELC 2011, on the subject of physical punishment, were selected for this study. Among these, 723 essays were used for fine-tuning ChatGPT, and the remaining 181 were reserved for testing the language model. Additionally, an extra set of 200 essays on different topics, such as driving and medical issues, was included to evaluate the language model’s performance across various themes. Inter-rater reliability indices, including measures like correlation, agreement, Cohen’s kappa, and Krippendorff’s alpha, along with many-facet Rasch measurement analysis, collectively indicated that the current version of ChatGPT (gpt-3.5-turbo-0613) is not yet poised to fully supplant human raters in essay scoring. Nevertheless, through the fine-tuning process, the model demonstrated a significant level of agreement with human raters and exhibited a marked degree of consistency.

Tıp Öğrencilerinin Biyoistatistik Sınavında ChatGPT-3.5 ve ChatGPT-4 Performanslarının Karşılaştırılması: Bir Eğitim Asistanı Olarak Artıları ve Eksileri

Studies have shown that the level of knowledge in biostatistics among medical students is lower than expected. This situation calls for the need to implement new methods in biostatistics education. The aim of this study is to evaluate the feasibility of ChatGPT as an education assistant in biostatistics. ChatGPT is a natural language processing model developed by OpenAI. It provides human-like responses to questions asked by users and is utilized in various fields for gaining information. ChatGPT operates with the latest GPT-4 model, while the previous version, GPT-3.5, is still in use. In this study the biostatistics performance of 245 Marmara University School of Medicine students was compared to ChatGPT-3.5 and ChatGPT-4 using an exam covering basic biostatistics topics. According to findings, ChatGPT-3.5 achieved 80% success rate in the exam, while ChatGPT-4 achieved 100% success rate. In contrast, the students achieved 67.9% success rate. Furthermore, ChatGPT-3.5 only recorded 33% success rate in questions requiring mathematical calculations, while ChatGPT-4 achieved 100% success rate in these questions. In conclusion, ChatGPT is a potential education assistant in biostatistics. Its success has increased significantly in the current version compared to the previous one. Further studies will be needed as new versions are released.

TRANSFORMATION OF THE SUBJECTIVITY OF THE MODERN INDIVIDUAL IN THE CONTEXT OF THE DIGITALIZATION OF SOCIETY

The article examines the state of formation of subjectivity in a modern individual, in particular, his or her attitude to social freedom. It has been clarified how these attitudes to freedom differ significantly from established, traditional ideas about this most important factor in the formation of a person. It is traced how ideas about freedom are connected with three types of societies, according to the conceptualization of M. Foucault – the society of the sovereign, the disciplinary society, the society of control in its current digital version – as a society of surveillance capitalism. The history of the emergence of the concepts of biopower, biopolitics and biomass in M. Foucault is analyzed, starting with the study of disciplinary society. It was revealed that in order to ensure the management of the masses of people and the control over each individual, biopower embodied a mechanism even in the times of the disciplinary society, which has gained further development in the modern society of control. Its main content involves the transformation of an individual into a social subject while preserving the totalization of the population as biomass. It is shown that the formation of modern subjectivity is simultaneously undertaken by the state in the form of performing a totalizing and individualizing function, from which the individual tries to slip away with the help of his practices and techniques of freedom that guarantee subjectivation. It is considered how the latest digital technologies adapt the socio-philosophical doctrine of neo-behaviorism, which justifies the control and formation of an individual's behavior at all levels of his life, and how this ensures the manipulation of freedom in the broadest sense and puts the population on the verge of endless survival. It can be stated that the launched worldwide technologies for managing the behavior of individuals as biomass and the process of individual digitization significantly transform the subjectivity of modern individuals. As a result of this long-term process of modern biopolitics, there is a possibility that individuals will lose the significance of freedom and the role of democratic institutions in society will decrease, and neoliberalism can become a «nurture medium» for the formation of digital totalitarian regimes.

Отдельные аспекты обжалования защитником решений суда, принятых в порядке досудебного производства

Appeal is the main way for the participants of the defense to defend their rights, since it allows the defender to challenge illegal procedural actions (inaction) and decisions of officials in the implementation of criminal pro-ceedings. Of particular interest is Part 5 of Article 165 of the Code of Criminal Procedure of the Russian Fed-eration, which fixes cases when investigative actions can be carried out without judicial sanction, limited only by the decision of the investigator or inquirer in circumstances that do not allow postponement. The current version of Part 5 of Article 165 of the Criminal Procedure Code of the Russian Federation does not provide for the pro-cedure for the participation of defense counsel and other interested persons in a court hearing when deciding on the legality or illegality of an investigative action that brooks no delay, such explanations are given exclu-sively in Resolution No. 19 of the Plenum of the Supreme Court of the Russian Federation. In this regard, the author considers it appropriate to include in Article 165 of the Criminal Procedural Code of the Russian Federa-tion the requirements for clarification of the right to participate in the court session devoted to the issue of estab-lishing the legality or illegality of the investigative action to the defense counsel, suspect, accused and other interested parties.

Evaluating ChatGPT Responses on Thyroid Nodules for Patient Education.

Background: ChatGPT, an artificial intelligence (AI) chatbot, is the fastest growing consumer application in history. Given recent trends identifying increasing patient use of Internet sources for self-education, we seek to evaluate the quality of ChatGPT-generated responses for patient education on thyroid nodules. Methods: ChatGPT was queried 4 times with 30 identical questions. Queries differed by initial chatbot prompting: no prompting, patient-friendly prompting, 8th-grade level prompting, and prompting for references. Answers were scored on a hierarchical score: incorrect, partially correct, correct, or correct with references. Proportions of responses at incremental score thresholds were compared by prompt type using chi-squared analysis. Flesch-Kincaid grade level was calculated for each answer. The relationship between prompt type and grade level was assessed using analysis of variance. References provided within ChatGPT answers were totaled and analyzed for veracity. Results: Across all prompts (n = 120 questions), 83 answers (69.2%) were at least correct. Proportions of responses that were at least partially correct (p = 0.795) and correct (p = 0.402) did not differ by prompt; responses that were correct with references did (p < 0.0001). Responses from 8th-grade level prompting were the lowest mean grade level (13.43 ± 2.86) and were significantly lower than no prompting (14.97 ± 2.01, p = 0.01) and prompting for references (16.43 ± 2.05, p < 0.0001). Prompting for references generated 80/80 (100%) of referenced medical publications within answers. Seventy references (87.5%) were legitimate citations, and 58/80 (72.5%) provided accurately reported information from the referenced publication. Conclusion: ChatGPT overall provides appropriate answers to most questions on thyroid nodules regardless of prompting. Despite targeted prompting strategies, ChatGPT reliably generates responses corresponding to grade levels well-above accepted recommendations for presenting medical information to patients. Significant rates of AI hallucination may preclude clinicians from recommending the current version of ChatGPT as an educational tool for patients at this time.

On the issue of procedural legal advocation of a civil plaintiff in criminal proceedings: doctrine and practical problems, ways to overcome them

The issue of the procedural status of a civil plaintiff in criminal proceedings and the issue of a person’s right to compensation for damage caused by a criminal offense has always been in the center of attention of lawyers - academics and practicing practitioners. The relevance of the chosen topic and the purpose of the research is due to certain doctrinal and practical gaps in the criminal procedural legislation of Ukraine, as well as contradictions between the norms of criminal procedural law, civil procedural law, and the provisions of inheritance law, which arise in the conditions of criminal proceedings, and are caused by death (or the condition, which makes it impossible to participate) of the injured person, who is a civil plaintiff in a civil claim for damages, at the stage of pre-trial and judicial criminal proceedings. Taking into account the set goal of criminal proceedings, which consists, among other things, in compensating the injured person for the moral and (or) property damage caused to him by a criminal offense, in this article the author not only analyzes individual scientific views and examines the relevant legal norms regulating procedural procedure of criminal legal succession, however, attention is emphasized and own proposals are made to improve the legal mechanism of legal succession of a participant in criminal proceedings, such as a civil plaintiff in a civil claim for damages presented in criminal proceedings. In conducting scientific research, the author used the formal-logical (dogmatic) method in interpreting the normative content of laws and formulating the definitions of individual legal concepts of the research issues, as well as the method of systemic-structural analysis, which contributed to the study of types of legal conflicts and gaps. Based on the results of the scientific research, the author outlined separate doctrinal and practical problems of the studied issue, and outlined the conclusions regarding the need to improve the current version of the Criminal Procedure Code of Ukraine and clarify the procedural rights of the civil plaintiff during procedural succession in criminal proceedings, by adding a new article to the Criminal Procedure Law, and made suggestions to the specified edition.

Spotivey: A web application for simplified use of the Spotify application programming interface in online questionnaire studies

Everyday music listening has become an important research topic during the last decades. However, self-reporting through questionnaire surveys, the received approach for studying individual music consumption, presents methodological challenges. The rise of mobile music streaming and open application programming interfaces introduces new opportunities to address these productively. Spotivey is a free research software that integrates music streaming provider API functionalities into online surveys and in this way allows to connect digital behavioral traces with self-reported questionnaire data. The current version effortlessly retrieves comprehensive information about respondents’ past music listening on Spotify while they fill an online survey. Through an informed consent procedure, General Date Protection Regulation compliance for this new form of digital data donation is ensured. Methodical challenges include participant dropout and the need for robust statistical analysis methods. Planned future enhancements encompass expanding application programming interfaces support, enriching retrieved data with information from other music databases, and compatibility with diverse online survey design systems.

HPC-driven computational reproducibility in numerical relativity codes: a use case study with IllinoisGRMHD

Reproducibility of results is a cornerstone of the scientific method. Scientific computing encounters two challenges when aiming for this goal. Firstly, reproducibility should not depend on details of the runtime environment, such as the compiler version or computing environment, so results are verifiable by third-parties. Secondly, different versions of software code executed in the same runtime environment should produce consistent numerical results for physical quantities. In this manuscript, we test the feasibility of reproducing scientific results obtained using the IllinoisGRMHD code that is part of an open-source community software for simulation in relativistic astrophysics, the Einstein Toolkit. We verify that numerical results of simulating a single isolated neutron star with IllinoisGRMHD can be reproduced, and compare them to results reported by the code authors in 2015. We use two different supercomputers: Expanse at SDSC, and Stampede2 at TACC. By compiling the source code archived along with the paper on both Expanse and Stampede2, we find that IllinoisGRMHD reproduces results published in its announcement paper up to errors comparable to round-off level changes in initial data parameters. We also verify that a current version of IllinoisGRMHD reproduces these results once we account for bug fixes which have occurred since the original publication.

Assessing ChatGPT's Proficiency in Simplifying Radiological Reports for Healthcare ProfessionalsandPatients.

Background Clear communication of radiological findings is crucial for effective healthcare decision-making. However, radiological reports are often complex with technical terminology, making them challenging for non-radiology healthcare professionals and patients to comprehend.Large language models like ChatGPT (Chat Generative Pre-trained Transformer, by OpenAI, San Francisco, CA) offer a potential solution by translating intricate reports into simplified language. This study aimed to assess the capability of ChatGPT-3.5 in simplifying radiological reports to facilitate improved understanding by healthcare professionals and patients. Materials and methods Nine radiological reports were taken for this study spanning various imaging modalities and medical conditions. These reports were used to ask ChatGPT a set of seven questions (describe the procedure, mention the key findings, express in a simple language, suggestions for further investigation, need of further investigation, grammatical or typing errors, and translation into Hindi). A total of eight radiologists rated the generated content in detailing, summarizing, simplifying content and language, factual correctness, further investigation, grammatical errors, and translation to Hindi. Results The highest score was obtained for detailing the report (94.17% accuracy) and the lowest score was for drawing conclusions for the patient (85% accuracy); case-wise scores were similar (p-value = 0.97). The Hindi translation by ChatGPT was not suitable for patient communication. Conclusion The current free version of ChatGPT-3.5 was able to simplify radiological reports effectively, removing technical jargon while preserving essential diagnostic information. The free version adeptly simplifies radiological reports, enhancing accessibility for healthcare professionals and patients. Hence, it has the potential to enhance medical communication, facilitating informed decision-making by healthcare professionals and patients.

Tax Office and Internal Affairs Bodies Cooperation in Initiating Criminal Tax Law Cases

The fight against tax crimes is carried out through cooperation of tax authorities with operational units of internal affairs bodies. In cooperation with tax authorities the operational units of internal affairs bodies (OVD) generally ensure the implementation of tax authorities powers to control and supervise compliance with legislation on taxes and fees. OVD are in fact participants in tax legal relations. At the same time, the insufficient development of legislation regulating these activities leads to legal uncertainty. In this regard, the authors propose to supplement Article 9 of the Tax Code of the Russian Federation with a clause fixing the status of internal affairs bodies as participants in relations regulated by the legislation on taxes and fees. At the same time, it is proposed to introduce some provisions into Articles 89–100 of the Tax Code of the Russian Federation regulating the powers and restrictions of an internal affairs body officer as a participant in an on-site tax audit. Changes in criminal, criminal procedure and tax legislation, which entered into force in 2022–2023, had a significant impact on the way economic security and anti-corruption units cooperate with tax authorities and preliminary investigation bodies in identifying tax crimes and initiating such criminal cases. Amid the changes in Federal legislation, the existing interdepartmental regulatory framework generally remains relevant, although it needs to be changed and updated. These measures are currently either unregulated or partially regulated in disparate departmental regulations of different legal force, which creates an objective need for the development and adoption of a single regulatory document. An acceptable orm of interdepartmental regulatory act may be a trilateral agreement on cooperation between the Investigative Committee of the Russian Federation, the Ministry of Internal Affairs of Russia and the Federal Tax Service of Russia. There is also a need to amend the Tax Code of the Russian Federation. It is important to eliminate the inconsistency of the current version of paragraph 3 of Article 32 of the Tax Code of the Russian Federation, which does not contain a complete list of decisions made by tax authorities to be sent so that to make a decision on initiating a criminal case. This results in a possibility of different interpretations of the relevant duty of tax authorities.