Cultural Labor Research Articles

Eicosanoid production by intrauterine tissues before and after labor in short-term tissue culture

Prostanoid production by intrauterine tissues from pregnant and non-pregnant women has been studied intensively over the last decade. Little is known about the lipoxygenase metabolites of arachidonic acid (AA). The production of prostaglandins and HETEs by pregnancy specific human tissues was investigated in a short-term culture system. Tissue samples were obtained after uncomplicated pregnancies from placenta, fetal membranes and decidua of deliveries before (n=6) and after the onset of labor (n=8) and incubated for 1 hour in oxygenated HBSS. In the supernatant, PGE 2, PGF 2α, 6-keto-PGF 1α and TXB 2 were measured with RIA and 15-, 12- and 5-HETE with HPLC and UV-detection. The main AA-metabolite in all tissue incubations was 12-HETE. Decidua produced 12 to 28 times more prostaglandins than placenta and fetal membranes with 6-keto-PGF 1α as the main metabolite. The main cyclooxygenase derivative measured from placenta and fetal membrane incubations was TXB 2. After labor, fetal membranes showed an increase in total prostaglandin (significant for PGE 2) and a decrease in HETE synthesis. The physiologic significance of 12-HETE in reproduction is still poorly understood, but a shift in AA metabolism from HETEs to prostaglandins may be involved in the initiation of labor. Furthermore, these results point to different roles of the tissue compartments within the pregnant uterus for the parturition process.

George Ovitt, Jr. The restoration of perfection: Labor and technology in medieval culture. New Brunswick, N.J.: Rutgers University Press, 1987. xiv + 272 pp. $32.00 (cloth) (Reviewed by Constance B. Bouchard)

Journal of the History of the Behavioral SciencesVolume 25, Issue 3 p. 244-246 Book Review George Ovitt, Jr. The restoration of perfection: Labor and technology in medieval culture. New Brunswick, N.J.: Rutgers University Press, 1987. xiv + 272 pp. $32.00 (cloth) (Reviewed by Constance B. Bouchard) First published: July 1989 https://doi.org/10.1002/1520-6696(198907)25:3<244::AID-JHBS2300250313>3.0.CO;2-IAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinkedInRedditWechat No abstract is available for this article. Volume25, Issue3July 1989Pages 244-246 RelatedInformation

The Attitude towards Labor in Early Christianity and Ancient Culture. Arthur T. Geoghegan

<i>The Attitude towards Labor in Early Christianity and Ancient Culture</i>. Arthur T. Geoghegan

Book Review: The Attitude toward Labor in Early Christianity and Ancient Culture

Book Review: The Attitude toward Labor in Early Christianity and Ancient Culture

The Attitude Towards Labor in Early Christianity and Ancient Culture

The Attitude Towards Labor in Early Christianity and Ancient Culture