Contamination Of Urine Specimens Research Articles

Contamination of urine specimens did not differ with collection technique in women with acute dysuria

Contamination of urine specimens did not differ with collection technique in women with acute dysuria

Contamination of urine specimens from women with acute dysuria did not differ with collection technique

Lifshitz E, Kramer L. Outpatient urine culture: does collection technique matter? Arch Intern Med2000 Sep 11; 160 : 2537 –40 [OpenUrl][1][CrossRef][2][PubMed][3][Web of Science][4] QUESTION: Does contamination of urine specimens from...

Sex and age-related differences in the urinary excretion of TXB2 in normal human subjects: A possible pathophysiological role of TXA 2 in the aged kidney

Urinary excretion of thromboxane B 2 (TXB 2), a stable metabolite of TXA 2, was measured by radioimmunoassay in 58 mormal subjects (17 males and 41 females) aged from 19 to 98 years. The basal level of urinary TXB2 in normal subjects was 100±6.7 ng/day (mean±SEM). In young males, contamination of urine specimens with seminal fluid, which is known to contain large amounts of prostaglandin E, did not change the level of urinary TXB 2. Urinary excretion of TXB 2 was significantly higher in male subjects than in female (124±12.6 vs 90±7.4 ng/day, p<0.05). There was no significant age-related difference in 24-h urinary excretion of TXB2 in normal subjects. However, when urinary excretion of TXB2 was expressed as a function of urinary creatinine excretion, it was significantly higher in the elderly (60–93 years old) than in the younger subjects (19–59 years old) (141±15.7 vs 99±7.7 ng/g creatinine, p<0.02).Renal TXA 2 may have a pathophysiological role in the functional impairment of the kidney in elderly people.