Central Construct Research Articles

L-phenylalanine-assisted construction of hierarchically structured Fe(OH)3@Co2(OH)2CO3 with enhanced catalytic activities for the degradation of persistent organic pollutants

In this work, a flower-like Fe(OH)3@Co2(OH)2CO3 catalyst was prepared via the confinement effects provided by L-phenylalanine, which favored the heterostructure construction of active iron centers (Fe(OH)3) anchored on the Co2(OH)2CO3 nanosheet supports. Benefiting from the created electron-transfer interface and dual metal active sites, the limitation of redox cycling was broken and exhibited highly efficient catalytic activities, the optimal Fe(OH)3@Co2(OH)2CO3 catalyst showed comparable catalytic performance for the degradation of dye (degradation degree of 99% methylene blue and orange II within 18 min). In addition, the prepared catalysts were employed for the efficient removal of antibiotics (tetracycline (98.9%), norfloxacin (92.5%) and doxycycline hyclate (90.2%). Besides, the preferred nanofibrous composite membranes prepared by combination of nanofibrous membranes (NFMs) with Fe(OH)3@Co2(OH)2CO3 catalysts possessed considerable potential for large-scale MB removal (treatment capacity of 238.5 L m−2 and permeability of 191.8 L m−2 h−1 driven by gravity) and stability (182.7 L m−2 of treatment capacity was achieved in the third run). The strategy of construction of rapid interface-redox on the heterogenous catalysts was designed to enhance catalytic performance, which provided a promising chance for the efficiently large-scale removal of dyes and antibiotics.

Combining WGCNA and machine learning to construct immune-related EMT patterns to predict HCC prognosis and immune microenvironment.

Hepatocellular carcinoma (HCC) is a malignancy with a very high mortality rate. Because of its high heterogeneity, there is an urgent need to find biomarkers that accurately predict prognosis. Epithelial-mesenchymal transition (EMT) is closely associated with frequent recurrence and high mortality of HCC. Therefore, it is necessary to comprehensively analyze the prognostic value and immunological properties of EMT gene in HCC. In our study, we performed bioinformatics analysis of the TCGA and ICGC liver cancer cohorts and identified the module genes of immune-associated EMTs (iEMT) by Weighted Gene Co-Expression Network Analysis (WGCNA). Further we used machine learning (support vector machines-recursive feature elimination and Lasso) to identify three central iEMT genes (ARMC9, ADAM15 and STC2) and construct iEMT_score. Subsequently, in the training and validation cohorts, it was demonstrated that the overall survival (OS) of patients in the high iEMT_score group was worse than that of patients in the low iEMT_score group. Based on this, we have constructed a nomogram that is easy for clinicians to use. In addition, our study explored differences in pathway enrichment, immunological properties, and sensitivity to common chemotherapy and targeted drugs in different subgroups of iEMT_score. Finally, we showed through in vitro experiments that knockdown of ARMC9 could significantly inhibit the proliferation, migration and invasion of HCC cells BEL7402. Taken together, our findings suggest that iEMT_score is an excellent biomarker for predicting prognosis and provide some new insights for personalized treatment of HCC patients.

ULOGA PSIHIČKOG NASILJA U PREDVIĐANJU PREDANOSTI I STABILNOSTI ROMANTIČNIH VEZA

Relationship commitment is one of the key constructsin studies on relationship quality and stability. In this study, the Investment Model (Rusbult, 1980) was used as a theoretical basis, where commitment is emphasized as the central construct for relationship maintenance and endurance. The aim of the study was to examine the role of psychological violence in predicting commitment and perceived relationship stability within the aforementioned model. The participants were students of the University of Zagreb (N = 154), with female students (77.9%) being more represented in the sample. The obtained results confirmed the assumptions of the basic model and all regression analyses resulted in a high percentage of explained variance of the examined criteria. The frequency of experiencing psychological violence was a significant negative predictor of commitment and perceived relationship stability, and this relationship was only partially mediated by other examined constructs. Contrary to expectations, more frequent experiencing of psychological violence also had a direct contribution in predicting less perceived relationship stability. The paper discusses the meaning of individual mediation effects and their contribution to explaining the relationships between the investigated constructs. The implications for future studies and for potential practical application of the results are also indicated. Key words: psychological violence; commitment; stability; partner relationships; Investment model

The effect of chief executive officers' regulatory focus on the entrepreneurial orientation of small and medium‐sized enterprises

AbstractEntrepreneurial orientation (EO) has been identified as a central construct to understand how firms compete and perform effectively in increasingly competitive environments. Drawing on regulatory focus theory, this study examines how chief executive officers' (CEOs') regulatory focus, a motivational attribute that entails a promotion focus for growth and a prevention focus for safety, affects the EO of small and medium‐sized enterprises (SMEs). Results from 110 UK SMEs show promotion focus positively, and prevention focus negatively affect EO when the two foci are examined independently. Our findings also demonstrate that EO varies significantly among firms led by CEOs with different combinations of the two foci. Specifically, firms engaged in significantly higher levels of EO when they are led by CEOs with a high rather than a low promotion focus, where prevention focus is at a high level. This study extends the literature by uncovering regulatory focus as a motivational microfoundation of EO.

Heart Failure Family Caregivers' Perspectives of Physical Activity Engagement: A Qualitative Study.

Research on caregiver burden and related psychological distress has been widely studied. However, little research has focused on perspectives and experiences of older family caregivers of persons with heart failure on engaging in physical exercise to improve their health and wellness. We investigated barriers and facilitators influencing physical activity engagement for older family caregivers of persons with heart failure through a qualitative descriptive study design utilizing participant interviews. The social cognitive theory framework guided the thematic analysis. Identified themes and subthemes that emerged were centered around the framework's interrelated personal, environmental, and behavioral factors. Self-efficacy emerged as a central construct facilitating engagement in physical activity. The older family caregivers embraced technology for physical activity interventions more readily since the COVID-19 pandemic encouraged increased technology use. The age-related and caregiving barriers to physical activity found in this study highlight considerations for an older family caregiver and guide interventions for future family caregivers' engagement.

ADOPTING ATTITUDE OF SELF--ESTEEM AND SELF CONFIDENT IN ENTREPRENEURIAL ACTIVITIES OF ORGANIZATION

Entrepreneurial Activities is an exciting and challenging journey that requires a unique set of skills and qualities. Over the years, studies have revealed certain characteristics that are common among successful entrepreneurs. Among these traits, self-confidence stands out as the most crucial attribute. Self-confidence forms the foundation upon which all other entrepreneurial qualities are built. This article delves into the significance of self esteem and self-confident that will provides practical strategies to nurture and maintain it .Self--esteem is a central construct in clinical, developmental, personality, and social psychology. Its role in psychological functioning has been studied for more than a century. Self-esteem construct has spawned a research literature of such magnitude and richness that it is impossible to summarize. Therefore, the aim of the present research was to highlight the main topics in this domain. That is, the self-esteem definition, dimensionality, and components; its formation and development, and assessment; the positive and negative effects of both high and low self-esteem, the association between low self-esteem and psychopathology especially depression, the dark side of high self-esteem (e.g.,narcissism) self-esteem and both culture and demographic variables associations were reviewed, and the stability of self esteem.

Study on the Construction of Hong Kong International Financial Center Based on SWOT Analysis

Hong Kong International Financial Center, as a world-class financial center. It will have a significant impact on the economy of China and the world. The Hong Kong economy has solved many problems for the society and successfully withstood the Asian financial crisis and the impact of being an international financial center. This paper will analyze and discuss the advantages, disadvantages, opportunities and challenges of the construction of Hong Kong international financial center in the form of SWOT. And put forward suggestions and prospects. It summarizes the advantages brought by Hong Kong in terms of regulations and financial markets to Hong Kong as an international financial center and maintains its position as an international financial center by taking advantage of the characteristics of diversification, moderate regulation and active trading. It also analyzes the disadvantages of the international financial center of Hong Kong in other cases and its inability to realize its dominant position in the market. At the same time, I hope it can provide ideas and enlightenment for those who are interested in this article and finance.

DEVELOPMENT OF THE REHABILITATION SYSTEM IN UKRAINE. ORGANIZATIONAL ASPECTS

The war and Russian aggression against Ukraine require government and society long-term extraordinary efforts. It’s not only in the field of the destroyed economy. The primary necessity is to restore a dignified life to every person affected by the war, military or civilian. The fate of each of us, our society, and our country in general will depend on efforts effectiveness in this direction. Objective. To develop and substantiate proposals for a systematic approach to the provision of medical rehabilitation assistance in the country. Results. The principles on which it is expedient to create a system of rehabilitation assistance in Ukraine have been formulated and substantiated. They are the principles of statehood, modernity, science, continuity, phasing and unified tactics, regionalism, specializations, self-rehabilitation. Each principle is briefly described, the experience of the world's leading countries is given. The stateand society role in the rehabilitation process is noted. Proposals. Develop a strategy, concept and government program for creating a rehabilitation assistance system in Ukraine. Provide a construction and equipment of regional rehabilitation centers (RC) within the post-war country renovation program. It has to be used worldwide principles of new hospital’s design and construction regarding the 200 inpatient beds in the unit. To locate RC outside of bigcities, usually. Training of rehabilitation specialists should be provided in various levels medical educational institutions. Modified vehicles to manual control for disable people and training in its use. To prevent the liquidation of Ukrainian Research Prosthetics Institution. To transfer this institution functions and the property complex to Sytenko Institute of Spine and Joint Pathology National Ukrainian Academy of Medical Sciences. To transfer research medical rehabilitation organizer and executor functions to the National Ukrainian Academy of Medical Sciences, in generally.

Problems and prospects of the federal project “Professionalitet” implementation as a tool for the secondary vocational education development

The paper considers the problems of implementing the federal project “Professionalitet”, which began in 2022 and is aimed at integrating technical schools (colleges) with enterprises of the real sector of the economy, with the participation of state support for the development of educational infrastructure at the expense of budget allocations of the federal budget.Based on the analysis of the performance of the indicators of the federal project “Professionalitet”, a generalization and systematization of the effectiveness of participation in it of the Rostov State Transport University was carried out. A systematic analysis of regulatory legal acts on the implementation of the federal project “Professionalitet” has been carried out, shortcomings of legal regulation have been identified and proposals for its improvement have been formulated.Taking into account the historically strong interaction of industrial technical schools (colleges) with railway transport enterprises, the old approaches in improving the activities of educational organizations for personnel training have been rethought and new approaches have been identified. The proposed approaches to the construction of educational and production centers (clusters) and the model of the infrastructure sheet can be useful for educational organizations when forming an application for participation in a competition for the creation and development of educational and production centers (clusters).The author suggests possible directions for the development of the federal project “Professionalitet”, first of all, meeting new trends in legislation in the field of education on the creation of educational and industrial complexes as part of educational organizations of secondary vocational education.

Exploring changes in family functioning when a child participates in a School‐Based Filial Therapy program

AbstractChild focus is a central construct within Bowen family systems theory (Bowen theory). A clinical implication is that mental health treatment focusing on a child may unwittingly reinforce the operation of child‐focused processes, which undermine rather than enhance child well‐being. The concept of child focus in Bowen theory presents significant implications for professionals working in school settings and in fields such as children's mental health, which are inherently child‐focused. Bowen theory is the guiding theoretical framework for School‐Based Filial Therapy (SBFT). SBFT is a play therapy intervention that was initially established in remote and outer‐regional New South Wales, Australia in response to the low availability of children's mental health services and the significant barriers associated with caregiver engagement in children's mental health treatment. It involves trained school personnel facilitating therapeutic play sessions with children experiencing emotional–behavioural problems. The intervention occurs on school grounds, during school hours, and children's family members do not participate in the intervention. This mixed‐methods study examines the impact of children's participation in SBFT upon family functioning. Interviews with caregivers (n = 10) of children who participated in 10 SBFT sessions were analysed using content analysis. Quantitative data were collected using the Differentiation of Self Inventory – Short Form and Visual Analogue Scale – Family Functioning. A Wilcoxon signed rank test was used to analyse the pre‐ and post‐data. Qualitative outcomes indicated changes in the categories of child functioning, caregiver functioning, and extended family functioning, whilst child‐focused processes remained dominant but changed in intensity and valence following SBFT.

Internet of things sports information collection and sports action simulation based on cloud computing data platform

In recent years, cloud computing technology has shown exponential growth, and the upgrading of hardware and the improvement of computing performance have brought significant changes to the Internet of Things industry. With the changes of the times and the emergence of many new demands, data platforms under cloud computing platforms must make corresponding changes according to the new demands. Among them, the construction of cross regional data centers is particularly important, especially in commercial environments. How to reduce the cost of data centers on cloud computing platforms while ensuring business quality has become a crucial issue. Based on the above situation, this article has optimized the bandwidth cost of the data center and solved the problem of big data transmission based on delayed big data windows and multi delay windows. A mathematical model for optimizing bandwidth cost under multi delay windows is proposed. This article also studied sports action simulation, which plays an important role in sports research, film animation, and virtual reality. Simulation actions are usually implemented based on data capture methods. However, these methods typically do not have interactivity with the environment. To enhance the authenticity and interactive ability of simulation action information collection, this article adopts reinforcement learning method for training and design, and applies a system of functions such as collecting human sports data processing. This article applies cloud computing data platforms and sports information collection to sports action simulation, making progress in the development of sports action simulation.

Rhodium-catalyzed enantio- and diastereoselective carboamidation of bicyclic olefins toward construction of remote chiral centers and axis

Rhodium-catalyzed enantio- and diastereoselective carboamidation of bicyclic olefins toward construction of remote chiral centers and axis

The impact of older adult care policy mixes on the construction of senior centers.

The problem of an aging population is becoming increasingly serious, and the establishment of senior centers helps to promote the physical health and mental health of the older adult, a key factor in achieving the high-quality development of the old-age security industry. The government has issued a number of policies to promote the establishment and development of senior centers. However, more and more older adult care policy mixes have gradually shown the phenomenon of poor policy connection, confusing standards, and even mutually exclusive content, resulting in many problems in the construction of policy-driven senior centers. Therefore, based on the overall perspective of the older adult care policy mix, this paper uses the GMM method to explore the impact of the comprehensiveness, balance, and consistency of older adult care policy tool portfolios issued by Chinese government agencies on the construction of senior centers in China. The empirical analysis results show that a comprehensive and consistent policy mix can promote the establishment of senior centers, while the balance of the policy mix will inhibit the establishment of senior centers. This paper analyzes the impact of older adult care policy on the construction of senior centers from the perspective of the policy mix, which helps to clarify the different policy effects produced by different policy mix characteristics and provides feasible policy suggestions for the government to formulate more reasonable and effective policies.

Total Synthesis of Asperaculin A.

The racemic total synthesis of asperaculin A, a sesquiterpenoid lactone with an unprecedented structure, has been accomplished in 17 steps from 3-methyl-2-cyclopentenone. Key features of the synthesis are the construction of a central all-carbon quaternary center using the Johnson-Claisen rearrangement, stereocontrolled introduction of a cyano group, and acid-mediated γ-lactonization.

NEED AND EXPECTATIONS FOR LEARNING IN A STEM ENVIRONMENT

In the last decade, the need for specialists in the field of engineering and exact sciences emerged in Bulgaria and around the world. This led to the launch of a National Program for the construction of stem centers in schools. From the Veliko Tarnovo region, 16 schools joined the program at different stages, where STEM centers are being built or are already functioning in various subjects, which significantly support the preparation of quality personnel for the Bulgarian economy. A review and analysis of the expectations of teachers and students from work in centers with an engineering focus and training in natural sciences was made. At the next stage, an analysis and evaluation of the effect of the implementation of these innovative centers will be done.

Regio- and Chemoselective Formal (4+1) Carbocyclization of Chalcones with Internal Alkynes via Rhodium(III) Catalysis.

A rhodium(III)-catalyzed oxidative cyclization of chalcones with internal alkynes is reported, generating biologically important 3,3-disubstituted 1-indanones along with reusable aromatic aldehydes. This transformation features unique (4+1) reaction mode, excellent regioselectivity in alkyne insertion, broad substrate scope, allows for the construction of quaternary carbon centers, and is scalable. Steric hindrance from substrate and ligand probably controls the chemoselectivity of this carbocyclization. Importantly, this discovery enables a practical two-step protocol switching the overall reaction of acetophenones with internal alkynes from a (3+2) to a (4+1) annulation.

Regio‐ and Chemoselective Formal (4+1) Carbocyclization of Chalcones with Internal Alkynes via Rhodium(III) Catalysis

AbstractA rhodium(III)‐catalyzed oxidative cyclization of chalcones with internal alkynes is reported, generating biologically important 3,3‐disubstituted 1‐indanones along with reusable aromatic aldehydes. This transformation features unique (4+1) reaction mode, excellent regioselectivity in alkyne insertion, broad substrate scope, allows for the construction of quaternary carbon centers, and is scalable. Steric hindrance from substrate and ligand probably controls the chemoselectivity of this carbocyclization. Importantly, this discovery enables a practical two‐step protocol switching the overall reaction of acetophenones with internal alkynes from a (3+2) to a (4+1) annulation.

The difficulties in emotion regulation scale: Dimensionality, measurement invariance, and physiological correlates in community adolescents.

Emotion regulation is a central construct for the study of mental health in adolescence. Although the Difficulties in Emotion Regulation Scale (DERS) has been vastly used, several issues remain unanswered (e.g., factor structure/dimensionality). This study aimed to validate the 36-items DERS in a sample of 989 Portuguese community adolescent (460 boys; 529 girls; age ranged from 14 to 18). A bifactor-ESEM model, comprising a general and six specific factors (nonacceptance; goals; impulses; strategies; clarity; awareness) was explored and considered the best fitting model. Gender measurement invariance was established. When compared with boys, although differences were small in magnitude, girls presented higher emotion regulation difficulties. Evidence for reliability and construct/temporal validity were found, and significant associations between the DERS and physiological measures of emotion regulation (i.e., Heart Rate and Heart Rate Variability) were established. Findings support the use of the DERS in adolescent samples.

Kajian Dampak Pengembangan Islamic Center Terhadap Kondisi Sosial dan Lingkungan

The Islamic Center is the center of Islamic religious activities. Islamic centers emerged in America as a place for the growing American Muslim population. In Indonesia, there are quite well-known Islamic Centers such as the Jakarta Islamic Center, the Samarinda Islamic Center, and the West Nusa Tenggara Islamic Center. The Islamic center is a place that functions as a center for fostering and developing the Islamic religion, besides that it also functions as a space for the development of da'wah in the era of development.
 The construction of the Islamic Center in Surakarta City is a part of the construction of the Raya Zayed Mosque which has been completed. The construction of Masjid Raya Zayed and Solo Islamic Center came from a gift from the Crown Prince of the United Arab Emirates (UAE), Sheikh Mohamed Bin Zayed Al Nahyan to President Joko Widodo. The construction of the Islamic Center is in line with the policy direction of the 2021-2026 City of Surakarta RPJMD, which is to increase efforts to use and control spatial planning with indications of the Optimizing the development of the North Solo Region program. This will balance the development of the North Solo Region and the development of the South Solo Region. Politically, the bilateral Islamic center is a symbol of friendship. The Solo Islamic Center that will be built is a collaboration between the governments of the UAE and Indonesia; Symbolizes good relations between the two countries.

Space-Isolated Chromophore for Organic Blue Phosphorescence with High Efficiency and a Deep-Blue Lasing Characteristic.

High-efficiency blue phosphorescence and deep-blue laser emissions play a crucial role in organic optoelectronic applications. However, designing metal-free organic blue luminescence with high energy levels of excited states and suppression of nonradiative transitions remains a formidable challenge. Herein, we demonstrate a synthetic strategy for achieving a deep-blue laser and efficient phosphorescence based on confining chromophores in the tetrahedral structure of sp3 hybridization. The data analysis reveals that the construction of the quaternary carbon center contributes to spatially separated donors and acceptors and considerable steric constraints, prompting an effective intersystem crossing (ISC) process and suppressing nonradiative transitions. The negligible interaction between chromophores simultaneously produces a deep-blue fluorescent laser and blue phosphorescence with an efficiency up to 82.3%. This work opens the door to multifunctional blue-emitting materials with high efficiency, providing a high-potential candidate for electrically pumped organic lasers and energy efficient light-emitting diodes.