The aim of the present study was to examine the surface characteristics and values of removal torque of an implant surface subjected to sandblasting with 125 µm Al 2 O 3 particles with a following immersion in biomimetic fluid and to compare that surface with a machined implant surface. Study protocol: Forty-eight conical implants were initially made of second-grade titanium alloy. The diameter of implants was 4 mm at the head and 2.6 at the apex, all implants were of 8 mm length and of large variable thread design. Half of them were subjected to sand blasting and immersion in biomimetic fluid at 37 °C for four weeks with daily replenishment of solution until the moment of placement; another 24 implants were left with untreated machined surface. Three-dimensional roughness values were obtained with the help of confocal laser scanning microscope. Forty-eight implants were implanted in 12 dogs. Twenty-four implants were retrieved after a 6-week healing period following installation, and the remaining 24 were removed upon the completion of 16 weeks, using a torque calibrator ((BTG150CN-S TOHNICHI) with a 20 cN·m - 150 cN·m scale of force registration was applied for the measurements of the removal torque. Results: The mean 3-dimensional roughness value of biomimetically treated implant surfaces was 1.34±0.24 µm and the mean roughness value measured for the machined surfaces was 0.33±0.04 µm (P<0.05). As to the average parameters of maximum peak-trough distance, these were equal to 2.85 for machined and 24.25 for incubated sandblasted implants. Machined implants demonstrated 49.5±10.3 removal torque values after the 6-week healing period. But for the immersed sandblasted implants the same parameter was equal to 72.7±15.98 cN·m. During a 16-week recovery period, these values increased up to 77.5±15.16 cN·m and 89.7±11.83 cN·m for machined and biomimetically treated sandblasted implants, respectively, P<0.05. Conclusion: The present study demonstrated the rapid recovery time for biomimetically incubated sandblasted dental implants in comparison to machined surface implants based on findings of early (6 weeks healing period) removal tests. Although there was established only a 13.4% difference in values of removal torque after a 16-week healing period (instead of 32% after 6 weeks of recovery) between two groups of implants which could be associated with delayed bone integration.
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