Level Of Zinc Concentration Research Articles

Zinc, copper and aluminium in the corpuscular components of peripheral blood in patients with pre-terminal and terminal renal failure

Trace elements play an essential role in the activation and regulation of metabolic processes. By using the flameless graphite furnace-AAS, accurate results can be obtained. In order to verify blood cells as more representative than plasma to reflect the whole body content of trace elements at uremic state, two patient groups, one with preterminal renal failure (n=40) and the second with chronic renal failure undergoing hemodialysis (n=20) were examined. The concentration levels of zinc, copper and aluminium were measured in different matrices, i.e. whole blood, plasma and corpuscular blood components. The analytical technique is eligible to isolate mono- and polymorphnuclear leucocytes for the determination of intracellular contents. In agreement with other reports, zinc and copper were decreased and aluminium was increased in the plasma of both patient groups. Different results could be found for intracellular contents with mean zinc concentration of erythrocytes, thrombocytes and leucocytes between mean and higher levels, though staying within normal values. Copper was decreased in erythrocytes and increased in thrombocytes, but not detectable in leucocytes. The results of this study point out the differences between the plasmatic and intracellular alteration of trace element contents in uremic patients. However, the concentration levels of all cellular compartments show high standard deviation, which shows the necessity of measuring additional matrices, e.g. plasma. Uremic symptoms relate to the disorders of the trace element homeostasis. Regarding the increased fragility of erythrocytes with shortened life duration, decreased copper contents could play an essential role. Increased aluminium concentration levels might also be one of the interfering factors in the uremic thrombocytopathy. Yet the measurement of the plasma content is inevitable to diagnose and reflect the whole body content of trace elements at uremic state. By keeping analysis control, important information about progression and influence of therapy can be obtained.

Effect of toluene inhalation on the liver and kidney trace element concentration levels in male wistar rats

In order to study the effect of toluene inhalation on the liver and kidney tissue trace element concentration levels, a study was done for 60 days involving 16 male Wistar rats. The control (Ce), 8 rats, were exposed to a stream of clean air only. The toluene exposed (Te), 8 rats, were subjected to 900 ppm of 99% pure toluene vapour. The exposure schedule was 6 hours per day, 5 days per week. Using Student's t test toluene inhalation decreased significantly the liver concentration levels of zinc. The results of this study also showed a significant increase in copper concentration levels caused by toluene inhalation in kidney tissues. The other trace elements, iron (Fe), manganese (Mn), cobalt (Co), cromium (Cr), nickle (Ni), and molybdenum (Mo), were also measured but their concentration levels were not significantly affected by toluene inhalation in this study. The results of this study suggest that toluene inhalation causes abnormal decrease of zinc concentration in the liver.

土壌‐植物系における亜鉛の挙動に関する基礎的研究（ＩＩ） 移行係数の推定手法に関する考察

Transfer factor (TF) is defined as the amount of material in the plant tissue divided by that in the soil. It is widely used to predict the amount of radionuclides transferred from the soil to edible parts of plant. But TF value varies greatly due to environmental factors and other growth conditions. In order to predict the precise amount taken up through plant roots using TF, the effect of those factors on TF should be considered.In this study, a model to estimate TF through plant root was proposed. This model is described as follows:TF=S·Tc/θr+Kd, where S is the selectivity [-]; Tc, the transpiration coefficient [ml/g]; θr, the soil water content by soil weight [ml/g]; and Kd, the distribution coefficient [ml/g].In experiments, the fluctuation range of S was investigated. The S was not affected by the zinc concentration level in nutrient solution when there were less than 0.15mmol zinc/l. The decrease of co-existing ion concentration in nutrient solution increased S, but the effect was considered to be small if no problem with the plant growth was observed. The TF calculated from the proposed model had considerably good agreement with the actual TF.

Zinc in teeth from children with and without cystic fibrosis

This study analyzes Zn concentration levels in teeth from children with and without cystic fibrosis with respect to different variables, namely: gender, age, type of teeth, area, fluoridation of water supply, term of pregnancy, maternal smoking habit, and maternal drinking habit. The method of analysis is proton-induced X-ray emission on crown samples. Atomic absorption spectrometry (AAS) studies on some of these samples show close correlation to the PIXE data. In general, the concentration level of zinc in teeth of children greater than 10 years old is less than the concentration level in teeth of children aged 10 years or younger for children who took nontetracycline antibiotics. Breast feeding-mixed feeding-bottle feeding show no significant difference in the zinc concentration in teeth.

Determination of Zinc in Very Small Body Hair Samples by One-drop Flame Atomic Absorption Spectrophotometry.

A method for determination of zinc contents in very small samples of hair was developed in order to estimate the zinc concentration in the human body. All steps from weighing of samples to ashing and preparation of the test solution were done in a tube designed by us to prevent contamination and to improve handling. Zinc concentration was determined with flame atomic absorption spectrophotometry aspirating a small volume of samples (80 microliters), by the so-called "one-drop method". Using this method, 5 mg of whiskers was analyzed every day for 10 days, and this revealed that the fluctuation of the zinc concentration level was very small and that it was possible to trace the individual level of zinc concentration daily. A sample of 5 mg is enough for the application of this method. Zinc concentration in the hair under the temple of a boy, and even the low-level zinc content of patients receiving total parenteral nutrition could be accurately determined every 10 days and monthly, respectively. The level of hair zinc contents for neonates was similar to that of adults.

ChemInform Abstract: Trace Metal Speciation by ASV. Part 7. Interaction of Zinc with Cl‐, NO‐ 3, I‐, SO2‐ 4, and OH‐.

AbstractThe stability constants of complexes of zinc with the title anions have been determined by the pseudo‐polarographic method at a zinc concentration level of 10‐8 mol/dm3.

Trace metal speciation by ASV Part VII. Interaction of zinc with Cl −, NO 3−, I −, SO 42− and OH −

The stability constants of zinc chloride, zinc, nitrate, zinc sulphate, zinc iodide and zinc hydroxide complexes have been determined by the pseudo-polarographic method at a zinc concentration level of 10 −8 mol/dm 3 in solutions of constant ionic strengths 4 mol/dm 3 and 0.5 mol/dm 3 (ZnOH x ). The zinc complexation constants obtained are compared with already published values determined at a zinc concentration a few orders of magnitude higher. Zinc forms five weak complexes with iodide ions. The distribution of Zn(II) ionic species in a buffered solution (pH 8.3) of chloride and sulphate ion was calculated by means of the experimentally obtained stability constants. The result indicated that the ZnOH + complex is the predominant ionic species in the solutions corresponding to natural estuarine and sea water.

The Effect of Zinc Concentration on Bone Growth in Rat

The higher level of zinc concentration in tumorous bone tissue of osteosarcoma have been reported in previous paper.The present study was performed in order to clarify the effect of zinc concentration on bone growth in rat.The increasing rate of body weight for 6 weeks, longitudinal length and zinc concentration of femur in rat were compared among the following three groups; A group: administrated with zinc deficient diet for 6 weeks, B group: 100p.p.m. zinc supplemented diet, C group: 500p.p.m. zinc supplemented diet.Both of the increasing rate of body weight (%) and the longitudinal length of femur (cm) in B and C group were significantly higher than those in A group.

Serum Zinc Concentration in Acute Myocardial Infarction

The serum zinc concentration was examined in 18 patients, 11 with well documented myocardial infarction and 7 patients with chest pain caused by myocardial ischemia without infarction. The zinc level fell sharply in the myocardial infarction patients within a day of onset, then rose to normal values within seven to ten days. There was no comparable change from normal values in the serum zinc level in seven patients with myocardial ischemia, although two showed borderline values. In two dogs with experimentally induced infarction the serum zinc concentration level also declined markedly in a manner similar to that observed in patients with infarction. It is suggested that under appropriate conditions measurement of serum zinc concentration levels may be a useful aid for differentiation of myocardial ischemia from infarction.