Body Composition Components Research Articles

Effects of a Meal Replacement on Body Composition and Metabolic Parameters among Subjects with Overweight or Obesity

Meal replacement plans are effective tools for weight loss and improvement of various clinical characteristics but not sustainable due to the severe energy restriction. The aim of the study was to evaluate the impact of meal replacement, specifically 388 kcal in total energy, on body composition and metabolic parameters in individuals with overweight and obesity from a Chinese population. A parallel, randomized controlled trial was performed with 174 participants (ChiCTR-OOC-17012000). The intervention group (N=86) was provided with a dinner meal replacement, and the control group (N=88) continued their routine diet as before. Body composition and blood parameters were assessed at 0, 4, 8, and 12 weeks. A post hoc analysis (least significant difference (LSD) test), repeated measurements, and paired T-test were used to compare each variable within and between groups. Significant (p < 0.001) improvements in body composition components were observed among the intervention group, including body weight (−4.3 ± 3.3%), body mass index (−4.3 ± 3.3%), waist circumference (−4.3 ± 4.4%), fat-free mass (−1.8 ± 2.9%), and body fat mass (−5.3 ± 8.8%). Body composition improvements corresponded with significant metabolic improvements of blood glucose (−4.7 ± 9.8%). Further improvements in visceral fat area (−7.7 ± 10.1%), accompanying with improvements in systolic (−3.7 ± 6.9%) and diastolic (−5.3 ± 7.7%) blood pressure, were only found in male subjects. To conclude, meal replacement intake with 388 kcal in total energy at dinner time for 12 weeks contributed to improvement in body composition and clinically significant metabolic parameters in both male and female participants with overweight/obesity. Additionally, glucose and blood pressure reduction were gender-specific highlighting the importance of gender stratification for design of nutritional intervention studies for improvement of health.

The effect of 8 weeks beta-alanine supplementation and resistance training on maximal-intensity exercise performance adaptations in young males

Objectives : The aim of this study was to examine the effects of 8 weeks beta-alanine (BA) supplementation with resistance training on some components of physical fitness and body composition in young males. Methods : Twenty healthy young men volunteered to participate for the study and divided into two groups and performed 8-week resistance training while supplementing with either BA or placebo (4.8 g per day). The subjects were evaluated for 1 repetition maximum (1RM) bench press and leg press, vertical jump (VJ), anaerobic power (RAST) prior to and after training intervention. In addition, body composition variables such as percent body fat, and BMI were assessed per and post training period. Results : Both the groups showed significant increases in 1RM bench press and leg press, VJ, and anaerobic power (RAST), and also the BA supplementation group showed greater gains compared with the placebo. In addition, percent body fat decreased significantly in BA and placebo groups, while no statistically significant changes were seen in BMI for the BA supplementation group and placebo group. Conclusions : The results indicated that resistance training improved physical performance and BA supplementation induced greater gains and therefore it could be recommend to coaches and athletes who use this supplementation to greater gains in physical fitness variables.

Bioelectrical impedance analysis of body composition and survival in patients with heart failure.

Studies have shown that higher body mass index (BMI) is associated with improved prognosis in heart failure (HF), and this is often termed the obesity paradox. Analysis of body composition may reveal that muscle mass rather than adipose tissue accounts for the obesity paradox. Bioelectrical impedance analysis of body composition in 359 outpatients with HF was performed using an In Body 520 body composition scale (Biospace Inc., California). Body fat and lean mass were indexed by height (m2 ). The cohort was stratified by median fat and lean mass indexed by height. The mean age of patients studied was 56 ± 14; mean left ventricular ejection fraction was 38 ± 16%. Patients with higher indexed body fat mass had improved 5-year survival over patients with lower indexed body fat mass (90.2% vs 80.1%, P = 0.008). There was also improved survival in patients with high vs low indexed lean body mass (89.3% vs 80.9%, P = 0.036). On multivariable analysis, higher indexed body fat mass, but not lean body mass, was independently associated with improved survival (HR 0.89, per kg/m2 increase in indexed body fat mass, P = 0.044); however, this was attenuated after adjustment for diabetes. The combination of low lean with low-fat mass was independently associated with poor prognosis. Our data suggest that higher fat mass-and to a lesser extent higher lean mass-is associated with improved outcomes in HF. Further investigations of specific components of body composition and outcomes in HF are warranted.

VolumE maNagement Under body composition monitoring in critically ill patientS on CRRT: study protocol for a randomized controlled trial (VENUS trial)

BackgroundDespite recent technical advances in the management of acute kidney injury (AKI), such as continuous renal replacement therapy (CRRT), intensive care unit mortality is still high, at approximately 40 to 50%. Although several factors have been reported to predict mortality in AKI patients, fluid overload (FO) during CRRT is a well-known predictor of patient survival. However, FO has been mostly quantified as an arithmetical calculation and determined on the basis of the physicians’ perception. Even though such quantification and assessment provides an easy evaluation of a patient’s fluid status and is a simple method, it is not applicable unless a detailed record of fluid monitoring is available. Furthermore, the method cannot differentiate excess water in individual water compartments but can only reflect excess total body water. Bioimpedance analysis (BIA) has been used to measure the nutritional component of body composition and is a promising tool for the measurement of volume status. However, there has been no prospective interventional study for fluid balance among CRRT-treated AKI patients using BIA. Therefore, we will investigate the usefulness of fluid management using the InBody S10 (InBody®, Seoul, Korea), a BIA tool, compared with that of generally used quantification methods.Methods/designThis will be a multicenter, prospective, randomized controlled trial. A total of 244 patients undergoing CRRT treatment will be enrolled and randomly assigned to receive either to InBody S10-guided management or to fluid management based only on clinical information for 7 days. The primary outcome is to compare the rate of euvolemic status 7 days after the initiation of CRRT, with a secondary outcome being to compare the 28-, 60-, and 90-day mortality rates between the two groups.DiscussionThis will be the first clinical trial to investigate the effect of using BIA-guided fluid management to achieve euvolemia in CRRT-treated AKI patients.Trial registrationClinicalTrials.gov, ID: NCT03330626. Registered on 6 November 2017.

Association Between Sport Participation, Body Composition, Physical Fitness, and Social Correlates Among Adolescents: The PAHL Study.

Background: Evidence suggests that social support impacts on participation in sport or physical activity (PA), and is associated with health benefits, although the link is complex and not well understood. The study aim was to examine whether participation in organized sports is related to body composition, physical fitness, and social correlates for PA. Methods: Cross-sectional data on 238 adolescents (90 boys and 148 girls), mean age 14.9 ± 0.8 years, who were participants in the Physical Activity and Health Longitudinal Study, were collected. The participants were divided into two groups: sport participation (SP) and non-sport participation (NSP). Height, weight, and triceps and subscapular skinfolds were assessed according to standard procedures. Weight (kg) and height (m2) were used to calculate body mass index (BMI), and skinfolds were used to calculate body fat percentage. The European Test of Physical Fitness (EUROFIT) battery of tests was used to assess physical fitness. The standardized International Physical Activity Questionnaire Short Form and Social Support for PA questionnaires were used to obtain information on PA and social correlates for PA, respectively. Participants were asked to choose between participation and non-participation in sport. Results: The SP group had lower BMI component values (p = 0.011, d = 0.52 for percentage body fat (%BF); p = 0.011, d = 0.53 for sum of skinfolds (∑SKF) obtained higher physical fitness scores in selected items (p = 0.003, d = 0.64 for sit ups (SUP); p < 0.000, d = 0.96 for maximal oxygen consumption VO2max) and received higher social support (p < 0.001, d = 0.86 for social support (SS)), than the NSP group. The social support received by those participating in sport correlated positively with most fitness components (p = 0.013, r2 = 18% for bent arm hang (BAH); p = 0.000, r2 = 12% for sit ups (SUP); p = 0.000, r2 = 17% for VO2max). Physical fitness components were negatively associated with most body composition components for both groups. Conclusions: The results provide a better understanding of sport participation in organized sports-related, body composition-related and physical fitness-related associations with changes in social support received by adolescents and may contribute to the development of more accurate promotive strategies to increase children’s and adolescents’ engagement in sport and PA.

Skeletal muscle reference for Chinese children and adolescents.

BackgroundSkeletal muscle as an essential body composition component plays an important role in maintenance of normal growth and development as well as systemic glucose metabolism in children. No nationwide reference data for skeletal muscle mass for Chinese youths are available in China. We aimed to establish the sex‐specific and age‐specific percentile reference values of skeletal muscle mass for Chinese children and adolescents.MethodsThis study consisted of 10 818 children and adolescents aged 3–17 years in Chinese urban area during 2013–15. Dual‐energy X‐ray absorptiometry scan was performed to measure whole body muscle mass and appendicular skeletal muscle mass. Lambda‐mu‐sigma method was used to obtain the sex‐specific and age‐specific percentile curves of muscle mass indices.ResultsOverall, whole body muscle mass and appendicular skeletal muscle mass indices showed an increasing trend with age for both sexes, with boys vs. girls having higher values of all muscle mass indices. Whole body muscle mass index in boys increased slightly before age 9 years and then increased rapidly until 15 years and slowed down thereafter, while the mean values in girls increased slightly before age 8 years, increased rapidly until 14 years and remained stable thereafter. Appendicular skeletal muscle mass index increased rapidly until age 16 years and then increased slightly for boys; by contrast, for girls, the mean values increased consistently before age 14 years but showed a slightly decreasing trend after that.ConclusionsThis study established sex‐specific and age‐specific percentile reference values for skeletal muscle mass for Chinese children and adolescents aged 3–17 years. These reference values can be used to evaluate the muscular development in Chinese children and adolescents.

ASSOCIATION BETWEEN BODY COMPOSITION AND CARDIORESPIRATORY FITNESS OF ADOLESCENTS

With the aim to investigate the association between body composition of adolescents and cardiorespiratory fitness, this research was carried out on a sample of seventh grade primary school students (38 female and 44 male students). The sample of measuring instruments for body composition assessment were: body mass index, triceps, subscapularis and suprailiac subcutaneous adipose tissue, body fat percentage, muscle mass percentage and fat-free mass. The “Beep” test was used for the assessment of cardiorespiratory fitness. At the multivariate level the results have shown that body composition, as a system predictor, explained 51% (p= .000) of variance of cardiorespiratory fitness of the total sample of students, 29% (p= .021) of the girls and 51% (p= .000) of the boys. At the univariate level of the total sample it was noticed that the sum of three skinfolds (t= -4.91; p= .000) and fat-free mass (t= 4.54; p= .000) had a high influence on system prediction. The sum of three skinfolds in the total sample, sample of girls and sample of boys had a negative impact on cardiorespiratory fitness. For the girls, body fat percentage had a positive impact on cardiorespiratory fitness, while in the total sample and sample of boys, fat-free mass had a positive impact on cardiorespiratory fitness. It could be concluded that the association between body composition components and VO2max was clearly demonstrated in adolescents.

Association between 25-Hydroxyvitamin D Status and Components of Body Composition and Glucose Metabolism in Older Men and Women.

Obesity and sarcopenia are major causes of morbidity and mortality among seniors. Vitamin D deficiency is very common especially among seniors and has been associated with both muscle health and obesity. This study investigated if 25-hydroxyvitamin D (25(OH)D) status is associated with body composition and insulin resistance using baseline data of a completed RCT among relatively healthy community-dwelling seniors (271 seniors age 60+ years undergoing elective surgery for unilateral total knee replacement due to osteoarthritis). Cross-sectional analysis compared appendicular lean mass index (ALMI: lean mass kg/height m2) and fat mass index (FMI: fat mass kg/height m2) assessed by DXA and insulin resistance between quartiles of serum 25(OH)D concentration using multivariable linear regression adjusted for age, sex, smoking status, physical activity, and body mass index (BMI). Participants in the lowest serum 25(OH)D quartile (4.7–17.5 ng/mL) had a higher fat mass (9.3 kg/m2) compared with participants in the third (8.40 kg/m2; Q3 = 26.1–34.8 ng/mL) and highest (8.37 kg/m2; Q4 = 34.9–62.5 ng/mL) quartile (poverall = 0.03). Higher serum 25(OH)D quartile status was associated with higher insulin sensitivity (poverall = 0.03) and better beta cell function (p = 0.004). Prevalence of insulin resistance tended to be higher in the second compared with the highest serum 25(OH)D quartile (14.6% vs. 4.8%, p = 0.06). Our findings suggest that lower serum 25(OH)D status may be associated with greater fat mass and impaired glucose metabolism, independent of BMI and other risk factors for diabetes.

The Relationship between Body Composition and a Gluten Free Diet in Children with Celiac Disease.

The primary and proven therapy, in cases of celiac disease (CD), is a rigorous gluten-free diet (GFD). However, there are reports of its negative effects in the form of nutritional deficiencies, obesity, and adverse changes in body composition. The study aimed to assess the impact of a GFD on the body composition of children with CD. In a case-controlled study (n = 41; mean age 10.81 y; SD = 3.96) children with CD, in various stages of treatment, underwent medical assessment. The control group consisted of healthy children and adolescents, strictly matched for gender and age in a 1:1 case-control manner. More than half of the examined children (n = 26) followed a GFD. CD children had significantly higher mean values of the fat free mass (FFM% = 80.68 vs. 76.66, p = 0.015), and total body water (TBW% = 65.22 vs. 60.47, p = 0.012), and lower mean values of the fat mass (FM% = 19.32 vs. 23.34, p = 0.015). Children who were on a GFD presented slightly higher, but not statistically significant, mean values of FM and FFM, than children who did not follow dietary recommendations (FM [kg] = 7.48 vs. 5.24, p = 0.064; FM% = 20.81 vs. 16.73, p = 0.087; FFM [kg] = 28.19 vs. 22.62, p = 0.110). After minimum one year of a GFD, CD children showed significantly higher values of FFM [kg] (p = 0.001), muscle mass (MM) [kg] (p < 0.001), TBW [L] (p < 0.001) and body cell mass (BCM) [kg] (p < 0.001). Furthermore, CD children who were on a GFD presented a significantly higher increase in weight (p = 0.034) and body mass index (BMI) (p = 0.021). The children adhering to a GFD demonstrate a tendency towards higher indices of selected body composition components.

Low muscle mass and inflammation among patients with type 2 diabetes mellitus in Indonesia.

Chronic inflammation, as observed in type 2 diabetes mellitus (T2DM), is associated with complications. How chronic inflammation influences body composition in patients with T2DM remains to be investigated. Our study aimed to evaluate the difference of skeletal muscle mass between patients with and without inflammation indicated by plasma high sensitivity C-reactive protein (hs-CRP). Patients with T2DM were recruited from primary health care in Sleman district, Indonesia. Measurements were performed to obtain information on body weight, body mass index, waist circumference, waist-to-height ratio, total body fat, subcutaneous fat, visceral fat, mid-upper arm circumference, and muscle mass. Spearman's rank correlation was performed to test the correlation between hs-CRP level and several components of body composition. To test the difference of percent skeletal muscle mass between subjects with and without inflammation (hs-CRP ≥ 3 or < 3mg/dL), general linear model was utilized with adjustment for several variables. Analysis with p value of less than 0.05 is considered statistically significant. In all subjects, hs-CRP is correlated with skeletal muscle mass (r: - 0.343; p = 0.04), total body fat (r: 0.353; p = 0.04), and subcutaneous fat (r: 0.369; p = 0.02) but not visceral fat (p: - 0.065; p = ns). Significant difference of skeletal muscle mass between subjects with and without inflammation was found in all and female subjects after adjustment for covariates. There was a negative correlation between skeletal muscle mass percentage and inflammation indicated by hs-CRP in type 2 diabetes patients.

Key somatic variables in young backstroke swimmers

ABSTRACTThe purpose of this study was to estimate the optimal body size, limb-segment length, girth or breadth ratios for 100-m backstroke mean speed performance in young swimmers. Sixty-three young swimmers (boys [n = 30; age: 13.98 ± 0.58 years]; girls [n = 33; age: 13.02 ± 1.20 years]) participated in this study. To identify the optimal body size and body composition components associated with 100-m backstroke speed performance, we adopted a multiplicative allometric log-linear regression model, which was refined using backward elimination. The multiplicative allometric model exploring the association between 100-m backstroke mean speed performance and the different somatic measurements estimated that biological age, sitting height, leg length for the lower-limbs, and two girths (forearm and arm relaxed girth) are the key predictors. Stature and body mass did not contribute to the model, suggesting that the advantage of longer levers was limb-specific rather than a general whole-body advantage. In fact, it is only by adopting multiplicative allometric models that the abovementioned ratios could have been derived. These findings highlighted the importance of considering somatic characteristics of young backstroke swimmers and can help swimming coaches to classify their swimmers and enable them to suggest what might be the swimmers’ most appropriate stroke (talent identification).

Peculiarities of Physical Fitness and Body Composition of 5—7 Year-Old Children of Several Kaunas Preschools and Interaction between those Indexes

Childhood obesity is a key public health issue around the globe in developed and developing countries (Dugan, 2008). The recent worldwide increase in the prevalence of childhood obesity may be due in part to a decrease in children’s physical activity levels (Ball et al., 2001). It is necessary to develop early interventions to improve physical fitness in children and to prevent the increase of childhood obesity (Brunet et al., 2006). So, the aim of this study was to evaluate the body composition and physical fitness of children aged 5—7 years and to estimate the interaction between body composition components and physical fitness tests. Participants: 216 children participated in this study: 104 girls, mean age 5.90 ± 0.63 years and 112 boys — mean age 5.98 ± 0.50 years from Kaunas city (Lithuania) preschools. Methods: all the subjects have been measured for their height, body mass, waist circumference (WC) and skinfolds at 2 different places — triceps and subscapular. Body mass index (BMI) and percentage body fat mass (BFM) were evaluated. All the participants did four physical fitness tests including speed shuttle run, 20 meters distance run, standing long jump and throwing 1 kg ball. General physical fitness level was evaluated based on B. Sekita (1988) methods. Results. Results showed that BMI did not significantly differ between boys and girls, and was evaluated as “optimal” for both groups. BFM was significantly higher in girls (p &lt; 0.001), and WC did not differ between genders. But WC had a tendency to increase with age in both boys and girls. Strong relationship was observed between BMI and BFM (r = 0.660, r = 0.660 respectively; p &lt; 0.01), and between BMI and WC (r = 0.703, r = 0.826 respectively; p &lt; 0.01) for both boys and girls. The results of physical tests showed that boys did all the tests better than girls (p &lt; 0.01). When we evaluated the general physical fitness of each child, the results indicated that their physical fitness waslow, evaluated as “good enough” for most boys and girls. General physical fitness of children negatively but slightly correlated with BFM (r = –0.201; p &lt; 0.001), it indicated that higher BFM determined lower evaluation of general physical fitness.Conclusions. Optimal body weight, according to body mass index, percentage body fat mass and waist circumference, was established for the bigger part of children, aged 5—7 years old. This study shows that physical fitness of children was low — evaluated as “good enough” and negatively correlated with body fat mass, showing that high body fat mass negatively impacted physical fitness.Key words: body mass index, percentage body fat mass, waist circumference, physical fitness.

Body composition analysis and references in children: clinical usefulness and limitations.

The prevalence of obesity is increasing over the world. Especially in Asians compared to Caucasians, there has been a significant increase in the population with major chronic diseases. This has developed over a shorter time period which is associated with socioeconomic changes in recent decades and a greater predisposition to cardiometabolic disorders. Many Asians could be classified has having normal weight but with obesity as evidenced by body composition (BC) and fat distribution. Overweight in Asian adults is classified as a BMI > 23 kg/m2 and obesity as a BMI > 25 kg/m2. An effective strategy to manage the obesity epidemic by focusing on childhood obesity is needed because of the huge impact that obesity exerts on population health. However, monitoring tools are limited to anthropometry such as BMI and BMI z-scores which define overweight and obese as a BMI exceeding the 85th and 95th percentiles, respectively, on reference growth charts. To overcome the limitations of BMI, reference values for BC components have been produced using various techniques. The use of BC charts for children in personalized therapeutic approach has increased, although there is a lack of a consensus on a single reference technique. Zones on BC charts and the personalized values of BC components could be practical, especially for the detection of metabolically unhealthy normal weight (MUN) children. BC charts should be included in the growth chart package and BC monitoring through the entire life course will help us understand the association between growth, aging, health and disease.

Features of correlations of cerebral circulation indicators with anthropo-somatotypological parameters of the body in practically healthy young men of mesomorphic somatotype

The peculiarities of the relations of rheoencephalographic indices with anthropometric indices in the healthy domestic samples studied are an important diagnostic criterion and a marker of pathological states from the cerebral vessels in the studied somatotype. The purpose of the work is to determine the features of correlations of indicators of cerebral circulation with constitutional parameters of the body of practically healthy young men from Podillia with mesomorphic somatotype. On the base of the research center of the National Pirogov Memorial Medical University, Vinnytsya, conducted a comprehensive study of 62 practically healthy urban youths of mesomorphic somatotype, of inhabitants of the Podillia region of Ukraine in the third generation. All of them have undergone a rheoencephalography using a computer diagnostic complex; anthropometric study according to the scheme of V. V. Bunak; craniometry; determination of components and type of somatotype by J. Carter and B. Heath and components of body mass index by J. Matiegka and American Institute of Nutrition. The correlation analysis was performed using the Pearson method in the statistical package “Statistica 6.1”. In the practically healthy young men of the mesomorphic somatotype, the following multiple correlations of cerebral blood flow parameters with constitutional parameters of the body are established: direct of middle power (r = 0.36 to 0.38) correlations of the base impedance with indicators of the thickness of skin and fat folds on the lower extremity, the endomorphic component of the somatotype and the fat component of the body mass using the Matejko method; direct, predominantly average strength (r = 0.30 to 0.40), correlations of the rising part of the rheogram and time of rapid blood filling with all total and longitudinal body dimensions, distal epiphysis widths of the upper extremity, muscle mass component of the body by the Matiegka method, and the bone component of the body mass using the Matiegka method (only for the time of rapid blood filling), as well as the direct mean (r = 0.31 to 0.37) and weak strength (r = 0.26 in all cases), correlations of slow blood flow time with most longitudinal body sizes; inverse, mainly average strength (r = -0.30 to -0.44), correlations of the dicrotic index with all total, most of the longitudinal body sizes, most of the girth indices of the limbs, muscle and bone components of the mass of the body by the method of Matiegka and muscular by the method of the American Institute of Nutrition method, as well as direct, mostly average forces (r = from 0.30 to 0.47), correlations of indicators of tone of all arteries, tone of arteries of large caliber and tone of arteries of medium and small caliber with most longitudinal body sizes. Attention is drawn to the lack of reliable correlations of only the amplitude indicators with total body sizes. In the analysis of correlations of rheoencephalography indicators with constitutional parameters of the body in practically healthy young men of mesomorphic somatotype among all groups of indicators of cerebral circulation for time indicators, the largest number of reliable connections found, mostly with total body sizes (53.3%, here and thereafter from the total number of these indicators), longitudinal body dimensions (52.0%), body mass index components (20.0%), circumferential body dimensions (18.7%), width distal epiphyses long limb bone (15.0%) and cephalometric indexes (14.3%). The highest percentage of correlations with body diameters (14.3%), components of somatotype (13.3%), cephalometric indices (11.4%) and components of body composition (10.0%) were established for amplitude parameters; and for derivative indicators - with longitudinal body dimensions (45.0%), body total dimensions (29.2%), body sizes (16.7%), body composition components (15.6%), width distal epiphyses of long limb bones (12.5%) and diameters of the body (10.7%).

The Efffects of 8-week Pilates Mat Exercises on the Body Compoition and Level of Satisfaction of Female College Students

The purpose of this study is to identify the effects of pilates exercises on the body composition and satisfaction level of female college students, and, to do so, pilates classes were provided for female college students for 8 weeks. Their level of satisfaction was surveyed and their body composition before and after participating in the classes was also measured. Out of a total of 40 subjects, those who did not diligently participate in the pilates classes were excluded, and the data of 22 subjects who continued to participate in the classes were analyzed only. The components of body composition measured before and after the 8-week pilates exercise program showed that body fat percentage and abdominal fat percentage were reduced, while lean body mass increased. The level of satisfaction of the group of those who performed pilates exercises for 8 weeks showed positive effects. It will be necessary to develop various systematic and science-based pilates exercise programs that are customized for different age groups in order to reduce the level of the components of body composition associated with obesity.

Relationship of Incident Falls with Balance Deficits and Body Composition in Male and Female Community-Dwelling Elders.

Sarcopenia and obesity are reported risk factors for falls, although the data are not consistent and most studies do not make sex comparisons. We investigated whether falls were associated with balance, gait, and body composition, and whether these relationships are sex-specific. Secondary analysis of 4-year follow-up data from of the New Mexico Aging Process Study. Albuquerque, New Mexico. 307 participants (M, n=122, 75.8 yr. SD5.5; F, n=183, 74.6yr SD6.1). Gait and balance were assessed annually using the Tinetti test. Lean body mass (LBM), appendicular skeletal muscle mass (ASM), fat free mass (FFM), total fat mass (FM) were assessed annually by DXA. Falls were assessed using bimonthly falls calendars. Hazard ratios (HR) for 2-point worsening in gait and balance score and falls were calculated by Cox proportional hazard for men and women. Baseline balance deficits, and not body composition, represented the strongest predictor of falls. For the total balance score, the variables with significant sex interactions were ASM (Male-HR 1.02 95%CI 0.60-1.73; Female-HR 1.92 95%CI 1.05-3.52, p=0.03) and FFM (Male-HR 1.04 95%CI 0.64-1.70; Female-HR 1.91 95%CI 1.12-3.24, p=0.04), after adjustment for age, sarcopenia and physical activity. The body composition relationship with balance deficits was U-shaped with the strongest predictors being low LBM in males and high FM in females. Specific body composition components and balance deficits are risk factors for falls following sex-specific patterns. Sex differences need to be explored and considered in interventions for worsening balance and falls prevention.

Lean mass as a determinant of bone mineral density of proximal femur in postmenopausal women.

To verify which component of body composition (BC) has greater influence on postmenopausal women bone mineral density (BMD). Four hundred and thirty women undergoing treatment for osteoporosis and 513 untreated women, except for calcium and vitamin D. Multiple linear regression analysis was performed in order to correlated BMD at lumbar spine (LS), total femur (FT), femoral neck (FN) with body mass (BM), total lean mass (LM) and total fat mass (FM), all determined by DXA. BM significantly correlated with all bone sites in untreated and treated women (r = 0.420 vs 0.277 at LS; r = 0.490 vs 0.418 at FN, r = 0.496 vs 0.414 at FT, respectively). In untreated women, the LM correlated better than FM with all sites, explaining 179% of LS; 32.3% of FN and 30.2% of FT; whereas FM explained 13.2% of LS; 277% of FN, 23.4% of FT In treated women, correlations with BC were less relevant, with the LM explaining 6.7% of BMD at LS; 15.2% of FN, 16% of FT, whereas the FM explained 8.1% of LS; 179% of FN and 176% of FT. LM in untreated women was better predictor of BMD than FM, especialy for distal femur, where it explained more than 30% of the BMD, suggesting that maintaining a healthy muscle mass may contribute to decrease osteoporosis risk. Treatment with anti-osteoporotic drugs seems to mask these relationships. Arch Endocrinol Metab. 2018;62(4):431-7.

Supplementation with nutraceuticals produces changes in working horse’s blood parameters but not in their body composition

Background : : : : There is little scientific data about the effects of continuous supplementation with nutraceuticals over horse’s health and performance. Horse owners and veterinarians are still using supplements for horses without any kind of evaluations. At the Brazilian market is possible to buy hundreds of different products, but there is not private or state regulation over production and quality of these products. The absence of information about quality and efficacy of these products may contribute to mistakes in horse’s nutrition program. The objective of this research was to determine the effect of supplementation with a combination of nutraceuticals over some blood parameters (red cell count, total plasma proteins, free plasma glutamine and glutamate) and components of body composition in working horses. Materials, Methods & Results : There were 19 gelding horses, divided in two groups: nutraceutical (NUTR; n=10) and placebo (PLAC; n=9). Both groups received equivalent feeding regimens in regard to concentrate and grass, and did similar exercise program. NUTR group received their pellets with nutraceuticals, and PLAC group received a placebo during the morning meal. There is no visual difference between nutraceutical and placebo pellets. Body composition determination and blood collection were taken in three periods: pre-test, after 4 and 12 weeks of supplementation. Body composition was determined after evaluation of horse’s body mass by electronic scale associated with measurement of rump fat by ultrasound. Results showed that there were no significant changes in body composition during 12 weeks of supplementation in both groups, which had percentage of body fat around 13%. However, supplementation with nutraceutical produced significant changes (P Discussion : Supplementation with nutraceutical or placebo did not produce illness or other nutritional problem in the experimental horses during 12 weeks. Also, because the nutraceutical and placebo pellets were visually similar to horse’s grain, the experimental animals did not have problems to eat all feed during 12 weeks. During this period it was observed that NUTR group had some improvement of the blood parameters when compared with PLAC group (P 16%), total plasma protein (>7%) and free plasma glutamine (>20%) observed in NUTR group will contribute to horse’s performance since it is positive action on red blood indexes and plasma amino acid concentration, contributing to the well-being of this horse group. Increase in blood glutamine concentration observed in NUTR group without improvement of body composition was not expected because this amino acid is produced mainly by skeletal muscle. Increase in fat-free mass frequently is associated with improvement of blood glutamine concentration. Finally, initial elevation in few parameters in PLAC group at 4 weeks of supplementation probably was associated with improvement of general management practices. In conclusion, Supplementation with a nutraceutical combination, for 12 weeks, produces changes in the concentration of some blood parameters, but it didn’t modify the corporal composition. The elevation of those components can favor the transport of oxygen and nutrients in tissues leading to improvement in the horse performance.

Communications of cerebral circulation indicators with body structure and body size indicators in practically healthy young women of the middle intermediate somatotype

According to the data of modern scientific literature, to determine the risk groups of vascular diseases of the brain at the stage before the development of the disease, it is necessary to study the dependence of cerebral functional indicators of the population on their constitutional status, age, region of residence. The purpose of the study was to determine the features of correlations of cerebral blood circulation with anthropo-somatotypological characteristics of practically healthy young women of the middle intermediate somatotype. On the base of the research center of the National Pirogov Memorial Medical University, Vinnytsya conducted a comprehensive study of 30 practically healthy urban young women of the middle intermediate somatotype, in the third generation of residents of the Podillia region of Ukraine. All young women undergo rheoencephalography using a computer diagnostic complex; anthropometric research according to the scheme of V. V. Bunak; craniometry; determination of somatotype by J. Carter and B. Heath method and components of body mass index by J. Matiegka and American Institute of Nutrition (AIN) methods. The analysis of correlations of the obtained results was carried out using the Spearman method in the licensed statistical package “STATISTICA 6.1”. In practically healthy young women of the middle intermediate somatotype, the following multiple connections of indicators of cerebral circulation with anthropo-somatotypological parameters of the body are established: direct, mostly unreliable, average strength (r = 0.31 to 0.36) connections of most time indices with girth the thighs and time of rapid blood filling with one third of the indexes of the thickness of skin and fat folds (TSFF), the endomorphic component of the somatotype and fat component of the body mass using the Matiegka method; direct, mostly reliable, average strength (r = 0.36 to 0.51) connections of the index of tone of all arteries, tone of arteries of large diameter and tone of arteries of medium and small diameter with a third of the circumferential body sizes, most of the pelvic diameter and muscular component of the body mass by the AIN method, as well as the inverse, mostly reliable, mean strength (r = -0.37 to -0.41) connections of the artery tone ratio with the third of the indices of the TSFF and the endo- and mesomorphic components of the somatotype. Attention is drawn to the lack of reliable and average strength false correlations of amplitude indices with total body sizes, the parameters of the width of distal epiphyses of long limb bones and components of the somatotype; as well as time and derivative indicators - with total and longitudinal dimensions of the body. In the analysis of correlations of indices with rheoencephalogram with anthropo-somatotypological indicators in practically healthy young women of the middle intermediate somatotype among all groups of indicators of cerebral blood circulation for the derived indicators, the greatest number of reliable and average strength connections mainly found with body diameters (21.9%), components somatotype (16.7%), cephalometric indices (12.6%), girths of the body (11.6%), and components of the body composition (9.4%). For amplitudes indexes, the highest percentage of connections with cephalometric indices (14.3%), components of body composition (10.0%), body length (8.0%) and body diameters (7.5%) were established; and for time indicators - with TSFF (11.0%), with the circumferential dimensions of the body (10.7%), the width of distal epiphyses of long limb bones (10.0%).

Relationship between propulsive force of the arm, body composition and isokinetic muscle strength indicators in surfers

This study aimed to evaluate the potential relationship between body composition (percentage of fat mass (FM %), fat mass and lean mass), muscle function (e.g., muscles; deltoid side and front, pectoralis major and teres major) and the propulsive force of the arm (PFA). Sixteen competitive surfers (29.1 ± 7.3 years; 1.72 ± 0.06 m; 74.2 ± 1.4 kg) were assessed for height, body mass, body composition (dual-energy-DXA), muscle function and PFA. Pearson correlation analyses were used to verify the relationship between all variables. An inverse correlations were found between PFA and isokinetic parameters to 60o/s: external rotation (peak torque: r = -0.71; p = 0.014; total work: r = -0.75; p = 0.007; power: r = -0.72; p = 0.011) and internal rotation (peak torque: r = -0.61; p = 0.045; total work: r = -0.73; p = 0.010; power: r = -0.61; p = 0.045) and 300o/s: external rotation (peak torque: r = -0.79; p = 0.003; total work: r = -0.84; p&lt;0,001; power: r = -0.81; p = 0.002) and internal rotation (peak torque: r = -0.69; p = 0.017; total work: r = -0.72; p = 0.011; power: r = -0.69; p = 0.017). There was no significant correlation between body composition components and PFA (p&gt;0.05). Although correlations do not imply cause and effect, PFA is not correlated with body composition in surfers and these relationships are inversely related to the parameters of muscle function.