Complex reaction networks with positive and negative feedback can produce diverse nonlinear phenomena in open reactors, such as multistability and oscillations. pH oscillators driven by hydrogen or hydroxide autocatalytic processes show sustained oscillations in continuously stirred tank reactors (CSTR) but only a sharp pH switch in batch. Here, we present a numerical study on the dynamics of pH oscillators in a series of CSTRs. We show a critical residence time under which bistability and above which oscillations develop. The dynamics of the CSTR cascade show the cross-shaped phase diagram of nonlinear activatory inhibitory systems. In the domain of oscillations, one reactor starts to oscillate autonomously and induces forced complex oscillations in the following tanks with damped amplitudes. These results, with their practical implications, may contribute to understanding the recent experimental observations of nonlinear phenomena in the presence of a residence time ramp and inspire further research in this area.
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