High School Completion Research Articles

Fatores associados aos distúrbios músculo esqueléticos em trabalhadores da área administrativa em uma instituição de ensino

Introduction: Workers' quality of life is involved in the field of public health, which has been creating spaces for the identification and prevention of work-related diseases, especially musculoskeletal diseases, due to their scope and magnitude. Thus, a study was carried out with the objective of knowing the musculoskeletal symptoms presented by workers in a private institution. Objective: To identify the prevalence and risk factors associated with work-related musculoskeletal disorders. Methods: Data were collected through a cross-sectional study, and a questionnaire was applied to the sample of 62 employees who worked at the institution. The instrument was based on a questionnaire translated and validated for the Portuguese language: the NMQ "Nordic Musculoskeletal Questionnaire". Sociodemographic and occupational characterization variables were collected. The data were analyzed using univariate and multivariate logistic regressions at a significance level of 5%. Results: Among the workers, the following predominated: female; age group from 20 to 30 years old; complete high school; married with children. The highest prevalence of WMSD was in women. The associations found were: non-practitioners of physical activity in the "neck" region (OR 4.98, 95%CI 1.147 – 21.59); and the "wrist and hand" region (OR 6:22; 95%CI 1.5425.15); In the multivariate analysis (multiple logistic regression), the factors associated with pain were: physical activity women also those who did not practice physical activity reported more pain than those who practiced in the neck region 28 employees (73.3%); p= 0.039), with this the association between musculoskeletal symptoms and the variables physical activity and gender was observed. Conclusions: In this context, it can be concluded that there was a prevalence of pain among the professionals studied, and that this has a significant association with several aspects related to work, and some sociodemographic and health factors. In view of the results found, it is necessary to develop and implement strategies to alleviate the workload and avoid problems for these employees.

Factors Related to Employment of Transition-Age Youth With Intellectual Disability

This study examined the relationship between demographic factors and disability type and employment in transition-age individuals with intellectual disabilities who received state vocational rehabilitation services. The study conducted a cross-sectional secondary data analysis of the Rehabilitation Services Administration 911 dataset with an inclusion sample of 39,060 youth. Results indicated that race, ethnicity, gender, education level, and disability type correlated with employment. Specifically, individuals of transition age who were Black, Hispanic, female, had an intellectual disability, and had not completed high school were less likely to be employed than their counterparts who were White, non-Hispanic, male, had a disability other than intellectual disability, and had completed at least high school. These findings were consistent with the previous research. The authors posited that such research going forward would benefit from more studies utilizing primary data collection, mixed-methods designs, more discernment among modifiable and nonmodifiable demographic factors, and using an intersectionality lens to understand the cumulative effect of factors associated with disadvantage or marginalization (i.e., race and ethnicity) on employment in this population.

The importance of academic advising for dual credit and early college high school students

AbstractAcademic advising for dual credit and early college high school students is significant to postsecondary matriculation and degree completion of these students after high school graduation. Unstructured advising can lead students to take excess credits and have an unclear path to a postsecondary credential. This study focused on the importance of academic advising, ensuring a clear path is identified for each student participating in a dual credit or early college high school program. A qualitative survey identifying high school personnel's understanding of advising, needs to better serve students, and current challenges facing high school counselors is discussed. Quantitative data landscapes student demographics and attempted versus completed credits for both dual credit and early college high school students at multiple high schools. Practitioner recommendations underscore the need for college advising by a college advisor who is familiar with the college advisement process versus a high school counselor who focuses on high school completion needs.

Impact of Patient Education on Establishing Trust as the Medical Student Provider: A Student Run Free Clinic Experience

Background: Effective doctor-patient relationships are crucial for quality healthcare, and trust is central to this dynamic. Trust in healthcare comprises competence, empathy, communication, and shared decision-making. Patient education sessions offer a platform to enhance patient trust, especially amongst novice providers. This study investigates the impact of patient education sessions led by medical students on patient trust within the context of a student-run free clinic. Methods: At our student-run free clinic, we conducted a cross-sectional survey to collect patient data, including background information, trust in healthcare, and opinions on education sessions at a student-run free clinic. Results: Amongst the enrolled 24 participants, the demographics revealed a diverse racial composition, with a significant portion having not completed high school and the majority being either unemployed or on disability. Following attendance at patient education sessions, a high percentage of participants reported positive experiences, including improved rapport with medical student providers and a likelihood of returning for future services and following medication recommendations. Conclusion: This study highlights the significant role of patient education sessions in fostering trust between patients and providers, improving health behaviors, and enhancing the broader healthcare system's credibility. It demonstrates how such sessions empower patients, leading to better medication adherence and timely medical assistance seeking, while also suggesting their potential for implementation across various healthcare settings to improve patient engagement and healthcare services.

Parental socioeconomic status and adolescent development in Indonesia

ABSTRACT We examine the impact of parental socioeconomic status on adolescent cognitive and non-cognitive development using data on adolescents from the 2014–15 Indonesian Family Life Survey. The analysis is relatively new for a developing country, by including non-cognitive skills and by looking at adolescents rather than young children. Parental education has a greater cognitive skills effect than parental income and job status, especially for fathers. For non-cognitive skills, parental job status is important but only for mothers. Education policy could therefore focus especially on high school completion and higher education enrolment, while employment policy could improve women’s job flexibility.

Ergonomic evaluation of assembly line work activity in the automotive industry: a case study

The automotive industry is growing worldwide with new technologies and seeking maximum cost savings. This sector is essential for the economic development of the country, with modern industries that invest in technological innovations and control of the activities of the production process. With this, the workstations become increasingly dynamic and characterized in the logic of productivity. Therefore, this study aimed to evaluate the work activity of operators of an assembly line of automotive components, from the ergonomic analysis. Through a descriptive and exploratory field study, the work activity of 30 operators of an assembly line of metallic components of the automotive industry was evaluated. Using instruments such as sociodemographic questionnaire; Nordic questionnaire; open interview, with collective questions about the development of the function, listed in an ergonomic demand items (EDIs) ranking; and complementary application of the NIOSH and OCRA methods. As a result, all respondents were male, with an average age of 30.13 ± 8.57 years, most had completed high school (76.7%), with an average working time in the company of almost two years (21.93 ± 12 months). Regarding relationships with coworkers, it was observed that the sector has a great relationship during the activities, with both colleagues and the boss. This study demonstrated a lower frequency of musculoskeletal symptoms in operators when compared to other studies. Symptoms that caused work leave were neck (3.3%), shoulders (3.3%), upper (6.7%) and lower back (6.7%), and hips/thighs (6.7%), ankle/foot (6.7%) were reported.

Upward Bound Program Supports Success of Low-Income and/or First-Generation College Students at a STEM-Focused HSI

A deeper understanding of low-income and first-generation college student experiences is essential to advancing diversity and equity in higher education. Due to a significant gap in college enrollment and graduation rates for low-income and first-generation college students, specifically after COVID-19, it is important to identify factors affecting their success. The Upward Bound Math and Science (UBMS) Program at New Mexico Tech (NMT) supports high school students who are either first-generation college students and/or from low-income families to prepare them with the skills and motivation necessary to complete high school and enter and succeed in a program of postsecondary education. These students face unique challenges during their time at college. To identify the factors that affect the success of these students, we surveyed several of our UBMS program participants who chose to attend NMT after completing high school. All participants said support from UBMS staff was critical when starting college at NMT. Participants also mention building a support system with their fellow UBMS alumni to deal with the struggles that being at STEM-focused institutions brings. This study also resulted in several suggestions for faculty and staff members to improve academic outcomes for all students.

Suicides among construction workers in the United States, 2021.

Construction workers have the second highest suicide death rate; despite this, there is limited literature examining suicides in the industry, which is necessary to identify those at higher risk of death by suicide. The objective of this study was to examine the characteristics of those who died by suicide in construction to address this knowledge gap. Data from the National Center for Health Statistics National Vital Statistics System 2021 public use Mortality Multiple Cause-of-Death file were used to identify deaths by suicide, while denominator data for rates come from the 2021 Current Population Survey. In 2021, construction workers were disproportionately affected by suicide deaths. Almost a fifth (17.9%) of deaths by suicide with a reported industry code were in construction, despite construction workers accounting for only 7.4% of the workforce. Male construction workers accounted for a majority (97.8%) of suicide deaths. The highest percent of deaths by suicide were among individuals who were white, non-Hispanic, completed high school or equivalent, and single, across construction and all industries for males and females. Male and female construction workers had the highest rates of suicide across all characteristics when compared to all industries. Our findings support the need for ongoing prevention efforts within the industry. Future research is needed to understand suicide risk among certain characteristics and occupations. In addition, the work environment or other work-related factors should be studied to understand how the unique nature of the construction industry may be associated with higher suicide rates.

Recognition of Prior Learning: How Its Impact on Village Official Competencies?

Recognition of Prior Learning (RPL) represents an educational innovation necessitating adaptability and flexibility from academic institutions. Village officials must bridge the knowledge gap, as many have only completed high school. This study investigates the effectiveness of RPL in enhancing the competencies of village officials in Indonesia. The sample included 1,260 village officials across Indonesia, divided equally into 28 experimental and control groups. Data were gathered using a job competency assessment scale. Findings revealed a significant competency improvement in the experimental group following RPL implementation compared to the control group. This underscores the importance of RPL, inspired by Experiential Learning Theory and Job and Performance Theory, in fostering competency development through work activities. Continuous application of RPL is essential, tailored to the specific competency needs of various job types, with ongoing monitoring and evaluation to ensure quality.

Street Mathematics as an Applied Technique in Solving Problems of the Market Vendors in the Municipality of Talavera, Nueva Ecija: A Case Study

This study aimed at identifying and analyzing the techniques applied in street mathematics in solving problems. It involved a total of ten(10) market vendors selling different products in the public market of Talavera, Nueva Ecija. Using the Descriptive Case Study Design, the following were the findings of the study: (1) The salt, shoe and utensil vendors did not finish elementary; chicken vendor completed elementary; fish and fruit vendor were not able to finish high school; vegetable and cloth/RTW vendor were high school completers; grocery/cooking oil vendor have reached college; and school supply vendor finished college. (2) The techniques used by the participants in solving problems are learned through their personal experiences, which include mental computations, finger counting, arithmetic, computations by pattern, question analysis, guess and check method, and written computations; (3) The market vendors’ calculations, sometimes, end up with wrong summation of the total amount of items. However, it can be overcome through written computations; (4) The instructional module can be used as a teaching guide to teach students the strategies for using street mathematics to solve mathematical problems. So that, students will discover the beauty of mathematics and learn how to approach problems in an informal way. In view of the aforementioned findings, the following conclusions are drawn; (1) Regardless of the educational background, the participants have mastered the principles of street mathematics which they apply when they perform calculations while selling. (2) The selected market vendors solved the given problems in pragmatic way. (3) The problem-solving skills of the market vendors have limitations because not all the techniques taught in school can be learned through their experiences in their workplace. (4) The instructional module will help the students learn some other strategies in solving mathematical problems independently, not only through formal approach but through informal approach as well.

Comparing Family Health Before and After a Family-Focused Nutrition Program during the Pandemic

IntroductionThe COVID-19 pandemic affected child health behaviors, leading to worse physical health. Given the importance of good family health in improved child health outcomes, this secondary cohort analysis tested the hypothesis that family health would improve from baseline to 12-week follow-up after participation in a novel family nutrition program.MethodsDiverse parent-child dyads participated in a home-based virtual Teaching Kitchen Outreach (vTKO) program (11 weekly healthy, low-cost recipes, cooking videos, and associated groceries delivered). The primary outcome was the Family Healthy Lifestyle Subscale (FHLS). Secondary outcomes were parent and child nutrition, and food insecurity. Statistical testing and modeling were used to evaluate pre-post outcomes.ResultsOf 123 enrolled dyads, 114 (93%) had sufficient data for analysis. Participants were 11% Hispanic, 54% Black, and 28% White; 31% completed high school or less; and 30% indicated food insecurity. Cohort mean pre-post FHLS scores significantly increased (25.5 vs. 27.3; p < 0.001). There were significant improvements in parent nutrition (p < 0.001) and child nutrition (p = 0.02 to < 0.001), but not in food security. After adjusting for baseline covariates, tobit regression found statistically significant pre-post FHLS differences (2.3; 95% CI=[1.4, 3.3]; p < 0.001).DiscussionParticipants in the novel home-based vTKO program reported improved family health over 12 weeks.

The Survivors: Syrian Young Adult Refugee Experiences Navigating the Quebec Education System

Canada resettled over 74,000 Syrian refugees since 2015. However, education programs lack awareness needed to successfully promote refugee academic integration. Little research focuses on young adult refugees (YARs) aged out of traditional schools due to asylum displacement and disrupted education, left with adult education schools as their only alternative to complete high school. Drawing upon 29 semi-structured interviews with Syrian YARs in Montreal, findings suggest that this subgroup is unintentionally excluded by educational policy-makers. Although YARs are survivors, their drive was found to be insufficient when confronted with systemic barriers that prevent at-risk students from proceeding smoothly through school to reach their highest potential.

Mid-life sleep is associated with cognitive performance later in life in aging American Indians: data from the Strong Heart Study.

Sleep-related disorders have been associated with cognitive decline and neurodegeneration. American Indians are at increased risk for dementia. Here, we aim to characterize, for the first time, the associations between sleep characteristics and subsequent cognitive performance in a sample of aging American Indians. We performed analyses on data collected in two ancillary studies from the Strong Heart Study, which occurred approximately 10 years apart with an overlapping sample of 160 American Indians (mean age at follow-up 73.1, standard deviation 5.6; 69.3% female and 80% with high school completion). Sleep measures were derived by polysomnography and self-reported questionnaires, including sleep timing and duration, sleep latency, sleep stages, indices of sleep-disordered breathing, and self-report assessments of poor sleep and daytime sleepiness. Cognitive assessment included measures of general cognition, processing speed, episodic verbal learning, short and long-delay recall, recognition, and phonemic fluency. We performed correlation analyses between sleep and cognitive measures. For correlated variables, we conducted separate linear regressions. We analyzed the degree to which cognitive impairment, defined as more than 1.5 standard deviations below the average Modified Mini Mental State Test score, is predicted by sleep characteristics. All regression analyses were adjusted for age, sex, years of education, body mass index, study site, depressive symptoms score, difference in age from baseline to follow-up, alcohol use, and presence of APOE e4 allele. We found that objective sleep characteristics measured by polysomnography, but not subjective sleep characteristics, were associated with cognitive performance approximately 10 years later. Longer sleep latency was associated with worse phonemic fluency (β = -0.069, p = 0.019) and increased likelihood of being classified in the cognitive impairment group later in life (odds ratio 1.037, p = 0.004). Longer duration with oxygen saturation < 90% was associated with better immediate verbal memory, and higher oxygen saturation with worse total learning, short and long-delay recall, and processing speed. In a sample of American Indians, sleep characteristics in midlife were correlated with cognitive performance a decade later. Sleep disorders may be modifiable risk factors for cognitive impairment and dementia later in life, and suitable candidates for interventions aimed at preventing neurodegenerative disease development and progression.

Outcomes of a program to improve breast cancer early detection in Cote d’Ivoire.

10553 Background: In Côte d'Ivoire &gt;70% of women with breast cancer are diagnosed with Stage III/IV disease. Patients pay for all diagnosis and treatment costs. We evaluated the effect of provider education, patient navigation and financial support on time from presentation to diagnosis and treatment uptake. Methods: Setting. Five participating primary healthcare centers in Bouaké. Intervention: (1) Breast health training curricula for primary care providers (PCPs), community health workers (CHWs), and patient advocates/cancer survivors (PAs), based on findings from a qualitative assessment. Content included benign breast disease, cancer diagnosis and treatment (PCPs); raising awareness about breast cancer (CHWs); and patient navigation and treatment adherence support (PAs). 36 PCPs, 5 CHWs, and 2 cancer survivors were trained. (2) For indigent patients (almost all patients), the program paid for imaging and pathology diagnosis; for those diagnosed with cancer, costs of bloodwork, imaging, and chemotherapy. Participants: Women with breast symptoms presenting to health centers from December 2022-September 2023. Primary outcome: mean time from presentation to diagnostic resolution. Results: 223 women enrolled in the study. Mean age was 33.7 (st. dev 13.2). 195 (87.3%) were pre-menopausal. 16 (7.1%) had a family history of cancer. 96 (43%) had no formal education, 42 (18.8%) completed primary school or high school, while 85 (38.1%) completed college or university. Time from noticing symptoms to presenting to healthcare center was &lt; 1 month for 96 (43%), 1-3 months for 33 (15%), 3-12 months for 28 (13%), and &gt; 12 months for 62 (28%). The most common symptoms were breast pain in 150 (67.3%) and painless mass in 119 (53.3%). 175 (78.5%) were referred to the gynecology service at the University Teaching Hospital Bouaké for evaluation. 71 (31.8%) were treated with plan for follow-up as needed; 37 (16.6%) continued with surveillance; 90 (43.4%) were referred for breast ultrasound; 26 (11.7%) for mammography; 42 (18.8%) for breast biopsy; 2 receive antibiotics. Among 106 (91.4%) who had imaging, mean time from presentation to the healthcare center to imaging was 14.5 days (st. dev 15.6 days). Among 42 who had a breast biopsy, mean time from presentation to biopsy was 34.5 days (st. dev 27.4). Mean time from presentation to biopsy result was 64.7 days (st. dev 33.0 days). Seventeen (7.6%) patients were diagnosed with breast cancer. Five (29.4%) are undergoing treatment, one was lost to follow-up, and one died. Nine (52.9%) patients declined treatment despite many discussions with patient advocates, mainly citing fear of side-effects. Conclusions: Our program achieved the mean time of &lt; 60 days from presenting to a healthcare center to diagnostic resolution either by imaging or biopsy recommended by the World Health Organization. Despite improving access to early diagnosis, program impact was limited due to suboptimal acceptance of treatment.

Choosing Honey Over Vinegar: Using Facebook as Intervention Platform to Save Bully Student from Dropping Out

With the purpose to save a bully student from dropping out, the study primarily used Facebook as engagement platform to initiate the ground for communication. The researcher consistently interacted with the learner's Facebook posts, offering positive and inspiring comments to foster a supportive online community. Celebrating achievements and offering empathy during setbacks, the researcher aimed to boost the learner's confidence and encourage continued engagement. With these dynamics, the study intends to yield data on these specific objectives: 1) To yield the frequency of the researcher's engagement with the student on Facebook in terms of Like, Chat, and Comment; 2) To identify other ways and resources extended to save the student from dropping out; and, 3) To determine the personal advices extended by the researcher to save the student from dropping out. The results indicate that chatting on Messenger accounted for the highest frequency, totaling 3,686 times. Following this, the researcher liked the student's Facebook posts 1,746 times, while commenting on them occurred 2,037 times. Additionally, the researcher provided financial support, spending Php1,552.00 on transportation allowance and Php 873.00 on snacks for the student. The researcher continuously worked to boost the student's self-esteem and motivation, ensuring that he felt valued and encouraged to continue posting in the future. Additionally, the researcher closely monitored the student's activities and achievements, offering congratulations on successes and expressing sympathy during difficult times. The continuous interaction nurtured a profound connection between the researcher and the student, surpassing the conventional boundaries of the teacher-student dynamic. This deep bond led to the emergence of valuable life insights for the student, instilling a renewed determination to persevere and successfully complete senior high school. As a result, the student gained clarity of purpose and a strengthened resolve to overcome challenges and achieve academic success. Moreover, the study suggests that the Department of Education and school administrators should encourage supportive online communities to boost teacher-student social media use. Facebook should be used by teachers to motivate kids. Social media relationships with teachers can foster learning and personal growth.

Social and emotional competency development from fourth to 12th grade: Relations to parental education and gender.

Educators have become increasingly committed to social and emotional learning in schools. However, we know too little about the typical growth trajectories of the competencies that schools are striving to improve. We leverage data from the California Office to Reform Education, a consortium of districts in California serving over 1.5 million students, that administers annual surveys to students to measure social and emotional competencies (SECs). This article uses data from six cohorts of approximately 16,000 students each (51% male, 73% Latinx, 11% White, 10% Black, 24% with parents who did not complete high school) in Grades 4-12. Two questions are addressed. First, how much growth occurs in growth mindset, self-efficacy, self-management, and social awareness from Grades 4 to 12? Second, do initial status and growth look different by parental educational attainment and gender? Using accelerated longitudinal design growth models, findings show distinct growth trends among the four SECs with growth mindset increasing, self-management mostly decreasing, and self-efficacy and social awareness decreasing and then increasing. The subgroup analyses show gaps between groups but patterns of growth that are more similar than different. Further, subgroup membership accounts for very little variation in growth or declines. Instead, initial levels of competencies predict growth. Also, variation within groups is greater than variation between groups. The findings have practical implications for educators and psychologists striving to improve SECs. If schools use student-report approaches, predicting steady and consistent positive growth in SECs is unrealistic. Instead, U-shaped patterns for some SECs appear to be normative with notable declines in the sixth grade, requiring new supports. (PsycInfo Database Record (c) 2024 APA, all rights reserved).

Abstract PO2-10-05: The Impact of Socioeconomic Factors on Breast Cancer Diagnosis in Latin America: The LATINA study (LACOG 0615/MO39485)

Abstract Background: Breast cancer (BC) is the most common malignancy and one of the leading causes of cancer death in women in Latin America (LATAM). Studies have highlighted the importance of understanding contextual characteristics of each patient population to inform health policy-making. However, few data are available on women from LATAM, a region with marked inequalities. Methods: LATINA (LACOG 0615/MO39485) is a multicenter prospective cohort study designed to describe sociodemographic characteristics, diagnosis, treatment, and outcomes of patients with BC in LATAM. Female and male patients aged ≥18 years newly diagnosed (i.e., &amp;lt; 12 months from research site activation) histologically confirmed clinical stage I-IV BC were enrolled. Eligible patients provided informed consent and had data collected from medical records at diagnosis and every 6 months up to 5 years. Results: Between February 2020 and August 2022, 3276 patients with BC from 31 research sites in 10 LATAM countries were included. Median age was 54 years (range 23–95), 91.8% (N=3008) were Hispanic or Latinos, the majority (68%, N=2224) were diagnosed with stage II or III BC, and 73% (N=2362) were treated in the public health system. Age, stage and detection method stratified by education level, marital status and employment status are shown in Table 1. Overall, 38.8% (N=1149) of patients had not completed high school. These patients were more frequently diagnosed by symptoms and diagnosed at later stages than those who had completed high school or college. Half of the patients were married/in a civil partnership at BC diagnosis (50.5%, N=1497). Unmarried patients were more commonly diagnosed by symptoms (71.7%, N=835 vs. 64%, N=916, p&amp;lt; 0.001) and with stage II/III BC (71.4%, N=868 vs. 67.6%, N=1038, p&amp;lt; 0.001) than married patients. Most patients (54.1%, N=1603) were not employed at BC diagnosis. Patients not employed were more frequently diagnosed by symptoms (68.8%, N=1044) than employees/self-employed (61.6%, N=675). After adjusting for age, country, health care provision (public or private), stage, and BC subtype, being diagnosed by symptoms was associated with not being married (adjusted odds ratio [aOR] 1.41, 95% CI 1.11–1.82, p=0.004), being not employed (aOR 1.41, 95% CI 1.08–1.84, p=0.011), and not having completed high school (aOR 1.46, 95% CI 1.00–2.13, p=0.031). Conclusions: Patients with a lower level of education, unmarried and not employed, are more likely not to perform BC screening and to be diagnosed by symptoms. Socioeconomic characteristics impact the method of detection of BC in LATAM and are associated with diagnosis at later stages. Further analyses of the LATINA study will provide invaluable data for informing regional health policy-making in LATAM. Citation Format: Gustavo Werutsky, Cynthia Villarreal-Garza, Henry Gómez, Juan Manuel Donaire, José Bines, Luis Henrique Fein, Maria Clara Horsburgh, Paula Cabrera-Galeana, Heloísa Resende, Rosa Vasallo Veras, Miriam Raimondo, Ricardo Elías Brugés Maya, Vidal Maria Del Rosario, Yeni Nerón, Ana Maria Donoso, Fernanda B. Damian, José D'Oliveira, Couto Filho, Maria Isabel Alonso, Victoria Costanzo, Tomás Reinert, Adriana Elizabeth Borello, Eduardo Cronenberger, Luis Fein, Marcela Urrego, Enrique Alanya, Jorge Luis Soriano García, Saúl Campos-Gomez, Eduardo A. Richardet, Hugo Castro-Salguero, Felipe Cruz, Diego Gómez, Angel Hernández, Carlos Alberto Farfan Tello, Ronald Rodríguez, Rafaela Jesus, Gustavo Gössling, Carlos Barrios. The Impact of Socioeconomic Factors on Breast Cancer Diagnosis in Latin America: The LATINA study (LACOG 0615/MO39485) [abstract]. In: Proceedings of the 2023 San Antonio Breast Cancer Symposium; 2023 Dec 5-9; San Antonio, TX. Philadelphia (PA): AACR; Cancer Res 2024;84(9 Suppl):Abstract nr PO2-10-05.

Abstract PO1-09-12: Cancer health disparities among patients with early-stage estrogen receptor-positive (ER+) breast cancer treated in public or private practices in Brazil

Abstract Background Cancer registries in Brazil are deficient and data about patients’ profiles and cancer treatment patterns are scarce in the country. Moreover, while 30% of population has access to private insurance, almost 70% of population uses publicly health services. The objective of this work was to describe the sociodemographic and clinicopathological characteristics of women with early-stage ER+ breast cancer on adjuvant ET in different regions of Brazil, and to describe treatment patterns for this disease according public and private institutions. Methodology: We performed a real-world data analysis in different institution regions of Brazil. Women with a history of early-stage ER+ invasive carcinoma of the breast on adjuvant endocrine therapy for at least 6 months were invited to participate of this study in 12 centers in four different regions in Brazil. Demographic and clinicopathologic information was retrieved from medical records. In order to compare healthcare insurance type, we considered patients who were treated under the Brazilian public health system as publicly insured, and women who had private insurance or paid for their treatment as privately insured. High education level was defined by completed high school. Data collection was done with RedCap software. Qualitative variables were compared between groups using the Chi-square or exact Chi-square test and for quantitative variables the non-parametric Mann-Whitney test was used. P &amp;lt; 0.05 was considered significant. Analyzes were performed in SAS 9.4; Results: From June 2021 to May 2023, a total of 461 women with ER+, early BC, were included in this analysis. A total of 233 (50.6%) came from private institutions, the mean age was 56.02 years (range 22-93), 47.69% were non-white, 61.3% were post-menopause, 61.7% lived with a partner, and 76.2% were highly educated and 66.81% had comorbidities. Tumor staging at diagnosis was classified as III, II and I respectively in 21.26%, 43.17% and 35.57% of all cases. Regarding treatment received, 62.4% of patients underwent lumpectomy, 32.2% had axillary dissection, 67.6% received (neo)adjuvant chemotherapy, 45.2% were on aromatase inhibitors and 14.19% were on ovarian function suppression plus ET . Median duration of ET use was 2.78 years (range 6 months- 9.61 years). Publicly health insurance was associated significantly associated with younger age at diagnosis (&amp;lt; 60 yo), premenopausal status, to live alone, lower educational level, more advanced tumors, prior mastectomy, prior axillary dissection, prior neo-adjuvant chemotherapy, prior radiotherapy, lower use of aromatase inhibitors, ovarian function suppression plus ET, and CDK4/6 inhibitors, while higher use of concomitant medications. Conclusion: The study shows significant health disparities among women with early-stage ER+ breast cancer treated in private versus public institutions in Brazil. Importantly, despite having more advanced tumors, women in public institution had less access to ovarian suppression, CDK4/6 inhibitors and were treated with more aggressive surgical procedures. A deep discussion involving government, lawmakers, health care providers and patients should be conducted to try to decrease the described disparities. Patient’s characteristic and patterns of treatment among patients with estrogen receptor-positive breast cancer on adjuvant therapy according to health insurance in Brazil ALND: axillary lymph node dissection; CDK4/6i: CDK4/6 inhibitors; ET: endocrine therapy; OS: ovary suppression. Citation Format: Romualdo Barroso-Sousa, Daniele Assad-Suzuki, Danielle Santos, Fernanda Moura, Sulene Oliveira, Anna Luiza Galvão, Bruno Souza, Amanda Castro, Monalisa Andrade, Andrea Shimada, Yuri Beckedorff, Maria Cristina Magalhães, Cristiano Souza, Carlos Paiva, Heloísa Resende, Daniela Pereira, Angelica Rodrigues, Daniela Rosa. Cancer health disparities among patients with early-stage estrogen receptor-positive (ER+) breast cancer treated in public or private practices in Brazil [abstract]. In: Proceedings of the 2023 San Antonio Breast Cancer Symposium; 2023 Dec 5-9; San Antonio, TX. Philadelphia (PA): AACR; Cancer Res 2024;84(9 Suppl):Abstract nr PO1-09-12.

Abstract PO2-29-03: Factors Affecting the Mammography Sensitivity and the Quality of the Breast Cancer Screening Program in the State of São Paulo, Brazil

Abstract Background: Previous researches found that false-positive mammogram results during breast cancer screening are related to age, family history of breast cancer, body mass index, and breast density. In Brazil, there is limited data available on possible factors that may influence the sensitivity of mammography and, consequently, the overall quality of the breast cancer screening program. Aims: This study aims to conduct a sensitivity analysis comparing the results of screening mammograms with diagnosis of breast cancer, taking into account factors that could impact this sensitivity. Methods: All mammogram and biopsy results in the state of São Paulo in 2013 were obtained from the Brazilian Breast Cancer Information System (SISMAMA) database. We obtained information on age (&amp;lt; 50, 50-59, 60-69, or 70+ years), type of lesion (solid, cyst, or calcifications), lesion size (&amp;lt; 10mm, 11-20mm, 21-50mm, or &amp;gt;50mm), lesion boundaries (defined or undefined), lesion characteristics (regular or irregular), and breast density (fatty/predominant fatty or dense/predominant dense). In addition, we evaluated the hormonal therapy usage (yes or no), radiotherapy treatment (yes or no), ethnicity (caucasian, asian, or black), education (illiterate, completed elementary school, completed high school, or completed higher education), skin type (retracted, thickened, or normal), and type of mammogram (simple or computerized). Our analysis focused on mammograms classified as BI-RADS 4, BI-RADS 5, and those with inconclusive results, which subsequently led to a biopsy for diagnosis. We conduct statistical analysis using SPSS v.29 software. To assess the agreement between mammograms and biopsy results (sensitivity), we calculated the proportion of true positive results. We compared the sensitivity across different strata of variables using the Chi-Square test and the V-Cramer measure. Results: A total of 6,064 women with BI-RADS 4, BI-RADS 5, or inconclusive mammogram results underwent biopsy procedures for breast cancer diagnosis. Among these cases, 3,414 (56.3%) were false positives, 1,765 (29.1%) were true positives, and 885 (14.6%) were inconclusive results. The sensitivity of mammographic screening was not significantly associated with ethnicity, education, type of mammogram, skin type, or previous radiotherapy. However, a higher proportion of false positive results was linked to high breast density (71.2%), irregular lesions with defined boundaries (87.5%), particularly calcifications (68.7%) smaller than 10 mm (67.5 %). True positive results, on the other hand, were associated with solid (87.1%) and irregular lesions with undefined boundaries (82.1 %), often larger than 50 mm (57.2%) in fatty breasts (82.7%). A notable proportion of inconclusive results was associated with the presence of dense/predominant dense breasts (88.4%) and irregular lesions with undefined boundaries (87%), particularly solid lesions (89.8%) ranging from 21 to 50 mm in size (60.8%). False positive and inconclusive results were more prevalent among women under 50 years old (79.8%) and those using hormonal therapy (54.8%) compared to true positives. This study has certain limitations, including the availability of data related to lesion density and morphology, as well as body mass index in the SISMAMA database, all of which can potentially impact mammography sensitivity. Furthermore, a notable limitation was a substantial number of missing values for ethnicity and education in the SISMAMA dataset. Conclusion: We identified associations between false-positive and inconclusive results on screening mammograms and factors such as age, breast density, lesion size, lesion types, and hormonal therapy. These results provide valuable information about potential factors that may affect the accuracy of mammography interpretations. Therefore, they must be taken into consideration when planning a breast cancer screening program. Citation Format: Alice Câmara, Lise Cury, Victor Filho. Factors Affecting the Mammography Sensitivity and the Quality of the Breast Cancer Screening Program in the State of São Paulo, Brazil [abstract]. In: Proceedings of the 2023 San Antonio Breast Cancer Symposium; 2023 Dec 5-9; San Antonio, TX. Philadelphia (PA): AACR; Cancer Res 2024;84(9 Suppl):Abstract nr PO2-29-03.

Abstract PO3-11-05: Sexual dysfunction among Brazilian women with early breast cancer on adjuvant endocrine therapy (ET)

Abstract Background: Sexual dysfunction is a common health problem in women, and it can occur during breast cancer treatment and survivorship. This study aims to determine the frequency of sexual disfunction among Brazilian women with early breast cancer on adjuvant endocrine therapy and to explore its relationships with patients’ clinical and social characteristics, adherence to ET, quality of life, return to work and healthcare insurance. Methodology: Women with history of early-stage ER+ invasive carcinoma of the breast on adjuvant endocrine therapy for at least 6 months were invited to participate of this study. Sexual dysfunction was evaluated using the Female Sexual Function Index questionnaire (FSFI). A score of &amp;lt; 26.55 in FSFI indicates sexual dysfunction. We evaluated sexually active patients (women should have at least one sexual intercourse in the previous four weeks). Demographic and medical information, site of treatment (private versus public), degree of education (completed high school vs not) were reviewed from medical records. Quality of life was assessed using EORTC QLQ C30 and BR-23 forms and adherence to ET was assessed by the Morisky Medication Adherence Scale (MMAS-8). Additionally, patients were interviewed about return to work. Data collection was performed using RedCap software and statistical analyzes were performed on the software R (R Core Team (2022). Qualitative variables were compared between groups using the Chi-square or exact Chi-square test and for quantitative variables the non-parametric Mann-Whitney test was used. Multivariable analysis was performed using Poisson regression. P &amp;lt; 0.05 was considered significant. Analyzes were performed in SAS 9.4. Results: From June 2021 to May 2023, a total of 461 women with ER+ early-stage breast cancer from 12 Brazilian institutions were included in this analysis. The mean age was 56.0 years (range 22-93 ), 47.7% were non-white and 38.7% were premenopausal. A total of 233 women (50.6%) had private insurance and the remaining were treated in public institutions. Median duration of ET use was 2.78 years (range 6 months- 9.61 years).Only 249 (54%) out of 461 patients who accepted to participate in this study declared to have sexual intercourse in the previous 4 weeks before evaluation and composes the population of this analysis. Sexual disfunction according results of FSFI questionnaire was found in 113 (53.3%) participants. Age was significantly associated with sexual dysfunction with women &amp;gt; 40 years-old having higher rates (95.3%) compared with versus younger patients (4.71% p=0.0069). Patients without sexual dysfunction had significantly higher EORTC QLQ C30 Global health status, Physical Functioning, Emotional Functioning, Sexual Functioning and Sexual Enjoyment scores than those with sexual dysfunction (p = 0.0060, p = 0.0242, p = 0 .0353, p = 0.0002 and p &amp;lt; 0.0001 respectively). ET duration between 2 and 5 years vs &amp;lt; 2 years, higher vs lower education level, EORTC QLQ-BR23 breast symptom and sexual functioning higher scores were significantly associated with the occurrence of sexual dysfunction in multivariated analysis (p &amp;lt; 0.05). Conclusion: In our study, only 54% of women evaluated had sexual intercourse in the previous four weeks and from those women 53.3% reported sexual dysfunction. Factors related to sexual dysfunction were higher education level, ET duration between 2 and 5 years, breast symptom and sexual functioning higher scores. div style=margin-top:10px; margin-bottom:20px;&amp;gt;Characteristic with adjusted prevalence ratios for the occurrence of sexual disfunction XX XX PR: prevalence ratio, EORTC: European Organisation for Research and Treatment of Cancer Citation Format: Daniele Assad-Suzuki, Fernanda Moura, Danielle Santos, Sulene Oliveira, Cristiano Souza, Heloísa Resende, Andrea Shimada, Anna Luiza Galvão, Bruno Souza, Amanda Castro, Monalisa Andrade, Yuri Beckedorff, Maria Cristina Magalhães, Carlos Paiva, Angelica Rodrigues, Daniela Pereira, Daniela Rosa, Romualdo Barroso-Sousa. Sexual dysfunction among Brazilian women with early breast cancer on adjuvant endocrine therapy (ET) [abstract]. In: Proceedings of the 2023 San Antonio Breast Cancer Symposium; 2023 Dec 5-9; San Antonio, TX. Philadelphia (PA): AACR; Cancer Res 2024;84(9 Suppl):Abstract nr PO3-11-05.