Introduction: A number of micro-organisms have been isolated from the oral cavity from dentulous patients. The chances of microorganisms to colonize complete denture surfaces as well as edentulous oral cavity are on the rise. Bacteria namely Streptococcus spp., Staphyloccus spp., Enterobacter spp., Klebsiella spp. Pseudomonas spp. and E.coli have been implicated in various cardiovascular, respiratory and gastrointestinal infections. All these bacterial spp. have been found to inhabit complete denture surfaces. Hence their isolation frequencies from complete denture have to be studied and compared by means of metaanalysis of similar studies. Methodology: Pubmed, Google Scholar, Open J Gate, Web of Science data bases were searched for relevant articles. Result: The isolation frequencies of the selective bacteria from the highest to the lowest is as follows: Streptococcus spp.(53.3%), Staphylococcus spp.(21.3), Enterobacter spp.(16.8%), Klebisella spp.(11%), Pseudomonas spp(6.1%). and E.coli (5.5%). Conclusion: Since the isolation frequencies of these bacteria are known, the appropriate disinfection methods of complete dentures targeting the various organisms have to be implemented to prevent systemic disease likely to be caused by their aspiration.
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