Vascular structures are assessed, e.g., in tumor surgery to understand the influence of a planned resection on the vascular supply and venous drainage. The understanding of complex branching vascular structures may benefit from immersive virtual reality (VR) visualization. Therefore, the estimation of distance, depth and shape information is a crucial task to support diagnosis and therapy decisions. Depending on the visualization techniques used, perceptual issues can influence this process and may thus lead to false conclusions. Many studies were carried out to study depth perception for different variants of vessel visualization. However, these studies are restricted to desktop applications. Since VR exhibits specific perceptual problems, we aim at an understanding of the appropriateness of vessel visualization techniques in VR. Therefore, this paper presents a user study that investigates the effects of three commonly used visualization techniques on depth perception. The set of visualization techniques comprises Phong shading, pseudo-chromadepth and fog shading. An immersive VR setup of the study using a head-mounted display (HMD) was compared to a traditional desktop setup. Results suggest that depth judgments are less error-prone and more certain in VR than in desktop environments. Moreover, depth-enhancing visualization techniques had greater effects in the desktop study compared to the VR study.
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