Common Complain Research Articles

Effect of chemotherapy on fatigue and presence of TNF- in breast cancer patients.

e20601 Background: Chemoterapy induced fatigue (CRF) is a common complain and few studies assessed so far the role of inflammatory biomarkers as predictors of CRF. OBJECTIVE: The primary objective of our study is to evaluate potential biomarkers of CRF in breast cancer (BC) patients receiving adjuvant Chemotherapy (CHT). Methods: Thirty-seven localized BC patients (clinical stages I-III) consecutively treated at the oncology service of Faculdade de Medicina da Fundação ABC were enrolled in this study. All patients received doxorubicin and cyclophosphamide based chemotherapy. Before the beginning of chemotherapy and before the second cycle, all patients answered the BFI (Brief Fatigue Inventory) questionnaire. The following inflammatory markers were collected: C-reactive protein (CRP), tumor necrosis Factor alpha (TNF-α) and interleukin 6 (IL-6). We correlated these inflammatory markers with BFI scores of each patient before and after cycle 1 and cycle 2 of chemotherapy. Results: The mean values of the inflammatory markers were: CRP 4.58 mg/dL (IC 95% 3.17-5.90), TNF-α 11 mg/dL ( IC 95% 8.84-13.79) and IL-6 3.74 (IC 95% 1.93-5.54). We observed a positive correlation between the BFI scores and TNF-α (p=0.0201). Conclusions: TNF-α may represent a potential CRF biomarker. Future studies may elucidate the potential usefulness of TNF-α for monitoring the anti-fatigue effects of new drugs for the treatment of CRF.

Study of Common Urinary Problems of Females at a Government Hospital in Central India

Aim: The aim of this study is to identify the common urinary problems in Indian females, their etiology and symtomatology. Material and Methods: This is a prospective epidemiological study of 703 female patients with urinary problems, who attended the surgery and gynecology OPD (outpatient department) in our institution which is a tertiary referral centre in central India. Result: 58% of patients were middle age (31 - 55) yrs. Burning micturition was the most common urinary complain (607 patients) followed by increased frequency of micturition (309 patients). 68% females took months or even years to take first consultation after appearance of their symptoms. 14% percent of patients suffered from urinary incontinence (stress, urge and mixed). 86% of women had education level below fifth standard. About 58% of females gave birth to 3 or more than 3 issues. About 254 (36%) patients had one or more unassisted delivery at home. Thirty eight percent of patients still remained undiagnosed. More than 50% of undiagnosed females lie in middle age group. 68% of undiagnosed patients took consultation months or years after their symptoms first appeared. Irritative symptoms are the most common presenting complains of these undiagnosed patients followed by pain in abdomen. Around 60% of patients had history of either mental distress, domestic violence or any neuropschiatric disease. This study only gives us an idea about the urinary problems faced by females and their probable causative factors. Many more studies need to be done involving multidisciplinary approach in order to benefit this section of our society.

The impact of tinnitus on sufferers in Indian population.

Tinnitus is a very common complain and affects 7% of population and has been associated with a range of physical and emotional disorders (Hallam et al. in Br J Clin Psychol 27:213-222, 1988). Hence to understand the distress caused by tinnitus and its relationship with the nature of tinnitus so as to suggest the appropriate treatment, there is the need to study the impact of tinnitus of a group of tinnitus sufferers. This study could be done on the basis of verbal description of tinnitus, Audiological measurement of tinnitus and psychological characteristics of tinnitus in terms of distress, anxiety, depression and disturbance of personality, to understand the impact of tinnitus on sufferers. Fifty adults in the age range of 18-60years with subjective tinnitus with bilateral normal hearing or pure SNHL ranging from mild to moderately severe were selected. An audiological profile of each subject was prepared on the basis of brief case history of subject, otoscopic examination, pure tone audiometry, impedance audiometry, frequency (pitch) and intensity (loudness) of tinnitus. A psychometric profile was developed by using Tinnitus Reaction Questionnaire and Nature of Tinnitus Questionnaire. These questionnaires were translated and adopted in Hindi and Bengali language after appropriate standardization procedure. 60% reported that they do not have any idea regarding probable cause of their tinnitus. 74% subjects of this study reported that there is no fluctuation in the pitch of their tinnitus. However, 68% reported loudness of tinnitus is fluctuating. A weak co-relation has been seen between traditional audiological measures like pitch matching, loudness matching and subject's description of pitch and loudness of tinnitus. There was a significant correlation between the impact of tinnitus and disturbance of sleep caused by it with increase in depression and anger (0.483). However, no significant co-relation was seen between distressed caused by tinnitus and duration of tinnitus (-0.034). The multiple nature/sounds of tinnitus had far more devastating effects or serious impact on 'tinnitus sufferers' than the single sound/nature. Gender differences were also found among tinnitus sufferers while assessing the audiological and psychological measures of tinnitus. Female subjects also reported a higher level of emotional reaction with a mean of 35.9 to their tinnitus as compared to males with a mean of 31.7. Tinnitus has resulted in multifold effects/impacts on tinnitus sufferers where it has made them feel unhappy, tense, irritable, depressed, annoyed, distressed and frustrated. It has interfered with their enjoyment, their relaxation, their sleep, and forced them to avoid quiet environmental and social situations. These findings should further help in the overall management of the patient suffering from tinnitus.

Prevalence et facteurs associes a l’halitose buccale : Etude dans une population generale senegalaise

Introduction: Halitosis is a common complain among dental patients, chronic among 50% of the adult population, and of oral origin in 90% of the cases. The objective of this study was to evaluate the prevalence and related factors of oral halitosis among a senegalese population. Material and method: This was a transversal descriptive study of 396 Senegalese adults using a 24-point self-assessment questionnaire on halitosis. All subjects were examined to estimate the organoleptic means and to measure the Sulfur Volatile Compounds (SVC), using a halimeter. Halitosis was diagnosed when the level of sulfur volatile Compound was ≥125 ppb and the organoleptic score ≥ 2. Data were statistically analyzed using the chi2 test. Results: The global prevalence of halitosis was 32.3 %. The difference was not statistically significant between male and female. Among the 396 patients suffering from bad breath, 128 had a permanent halitosis and 52 had a physiological halitosis. The means of the organoleptic scores were 3.12 and that of the (SVC) were 273.9 ppb. Conclusion: The results of the study showed a relation between the organoleptic tests and the level of sulfur volatile compounds (SVC). Keywords: Halitosis, organoleptic tests, sulfur volatile compound, epidemiology, and self-assessment.

Preliminary efficacy of CyberKnife radiosurgery for locally advanced pancreatic cancer

CybeKnife is a newly developed technology in the field of stereotactic radiosurgery/radiotherapy (SRS/SRT). Compared with conventional SRS/SRT, there are many advantages for CyberKnife in terms of treating tumors that move with respiration, being real-time image-guidance, frameless, high accurateness, and so on. Recently, it has been used to treat different types of malignant carcinoma including intracranial and caudomedial tumors. This study was designed to evaluate the short-term efficacy and toxicity of the CyberKnife radiotherapy for locally advanced pancreatic cancer. A total of 20 patients with locally advanced (stage II-III) pancreatic cancer treated with CyberKnife were recruited between April 2009 and December 2009. Of 20 patients, 13 were with cancer located at the pancreatic head and 7 were located at the pancreatic body and tail. The planning target volume (PTV) was defined as gross tumor volume (GTV) plus 2-3 mm, and more than 95% PTV should be covered by 75% isodose surface. The median of PTV was 47 cm³ (26-64 cm³). The median total prescription dose was 40 Gy (32-55 Gy) at 3-6 fractions. During treatment delivery, X-Sight Spine Tracking System was used in 5 patients to track movement of the tumor. Other 15 patients were implanted fiducials in the tumors to track movement of the tumor and patient breathing patterns. The median follow-up time was 7 months (3-11 months). All patients had finished the treatment and 19 were alive by the last follow-up. Slight fatigue was the most common complain. Evaluated by CT scan, 6 were complete response, 9 were partial response, 3 were stable disease, and 1 was progression; 1 was dead. There were 6 patients with grade I granulocytopenia, 7 with grade I nausea, and 5 with grade II vomiting. The CyberKnife radiosurgery for the locally advanced pancreatic cancer shows a high rate of local control and minimal toxicity. Long-term follow-up is necessary to evaluate the survival and late toxicity.

Chronic Rinosinusitis and Nasal Polyposis in Nepal

AbstractChronic rhinosinusitis and nasal polyposis is more common in the age group of 18 to 25 years. Urban population and housewives are more commonly affected. Common complains were headache and nasal blockage in 80% and 76.6% cases respectively. Polyps were common clinical finding in one third of cases. Subjective complete relief was seen in 83.3% of cases after FESS. Eight cases had minor postoperative complications

An initial report of cyberknife radiosurgery for primary hepatic carcinoma

To study the efficacy and toxicity of cyberknife radiosurgery for primary hepatic carcinoma. From September 2006 to March 2008, 17 patients with clinical stage I-III primary hepatic carcinoma were treated with cyberknife at Tianjin Cancer Hospital. 12 patients received previous treatment of surgery, or interventional therapy or radiofrequency therapy before the cyberknife radiosurgery. Totally 23 lesions in the liver were treatment. The median planning target volume (PTV) was 75 ml (13 - 351 ml). Fiducials were placed in or adjacent to the tumor one week before the CT scan simulation. The median total prescription dose was 45 Gy (range: 39 - 52 Gy) at 3-8 fractions and the median prescription isodose lines was of 78.0% (range: 75.0% - 81.0%. The follow-up time was 3-30 months (median: 14 months). All patients finished the treatment and slightly fatigue was the most common complain. There were 12 patients alive and 5 patients died. All the lesions in liver treated by the cyberknife radiosurgery achieved local control. The cyberknife radiosurgery for primary hepatic carcinoma showed a high rate of local control and minimal toxicity. Long time follow-up is necessary to evaluate the survival data and late toxicity.

ANTIEPILEPTIC DRUGS IN THE TREATMENT OF NEUROPATHIC PAIN: DRUG‐TO‐DRUG INTERACTION IN ELDERLY PEOPLE

To the Editor: Pain is a common complain in elderly people, often linked to neuropathic syndromes that affect old people particularly, such as trigeminal neuralgia, painful diabetic neuropathy, and postherpetic neuralgia.1 The effectiveness of anticonvulsant drugs in the management of neuropathic pain has been proven; for example, carbamazepine has been extensively employed and evaluated for pain relief in trigeminal neuralgia and has received Food and Drug Administration approval for this use.2–4 Nevertheless, carbamazepine has a narrow therapeutic window and has caused, albeit rarely, severe side effects, including hepatic failure, agranulocytosis, aplastic anemia, Stevens-Johnson syndrome, and toxic epidermal necrolysis. In addition, in polymedicated elderly patients, there is a high potential for adverse effects from drug-to-drug interactions, carbamazepine being a powerful inducer of the hepatic P450 cytochrome system. This could lead to reduced effectiveness of the drugs co-prescribed with carbamazepine. A 90-year-old woman was admitted to the hospital with exacerbation of long-standing arterial hypertension. She was also known to have symptomatic facial neuralgia, which had been treated with carbamazepine over many years. During her hospital stay, secondary causes of hypertension, such as pheochromocytoma and renal artery stenosis, were excluded. High systolic blood pressure measurements (range 240–260 mmHg) were noted several times daily despite pentatherapy (calcium channel blocker, loop diuretic, thiazide diuretic, angiotensin II receptor antagonist, and beta-blocker). Left ventricular hypertrophy was diagnosed according to echocardiogram. Other treatments with drugs that are not metabolized by the liver, in this case glyceryl trinitrate and moxonidine, appeared to be more effective. This observation suggested that the treatment resistance of the hypertension might be due to an effect of carbamazepine at the level of the antihypertensive drugs' hepatic metabolism. After discontinuing carbamazepine (replaced by gabapentin) and allowing sufficient time for its elimination, significant improvement in the blood pressure profile was observed; mean arterial blood pressures decreased from 177/64 mmHg (38 measures/24 h) to 157/65 mmHg (17 measures/24 h). Blood pressure measurements greater than 200 mmHg disappeared completely (>10 peaks/24 h previously), allowing the antihypertensive treatment regime to be reduced from five to three drugs. Some months after discharge home, carbamazepine was reintroduced for neurological symptoms, leading again to an uncontrolled elevation in blood pressure and hospital readmission. Carbamazepine has been reported to be associated with arterial hypertension and (more frequently) with exacerbation of preexisting hypertension through its effect on hepatic drug metabolism.5–7 Carbamazepine induces the cytochrome P450 enzymes 3A4, 2C9, and 1A2, which catalyze many antihypertensive drug types, for example, the calcium channel blockers, angiotensin II receptor antagonists, some loop diuretics (torsemide), and some alpha- and beta-blockers. Consequently, the pharmacological effect of these antihypertensive drugs is diminished. The hepatic cytochrome system does not metabolize other blood pressure–lowering molecules (such as angiotensin-converting enzyme (ACE) inhibitors, thiazide diuretics, potassium-sparing diuretics, agonists of alpha-2 central receptors, nitrates, and some beta-blockers (atenolol)), and hence the concomitant use of carbamazepine or other cytochrome P450–inducing drugs (e.g., rifampicin, dexamethasone, phenytoin, phenobarbital, and St. John's wort (Hypericum perforatum) does not affect their pharmacological effect. In addition to antihypertensive agents, cytochrome P450 metabolizes many other drugs, whose effect may also be expected to be compromised in the presence of carbamazepine. In our patient's treatment, cytochrome P450–metabolized drugs, including paracetamol, clopidogrel, omeprazole, zolpidem, and mianserin, were prescribed. The clinical case presented here illustrates the importance of considering potential drug-to-drug interactions whenever an anticipated therapeutic effect is not realized. The phenomenon of induced or exacerbated hypertension by carbamazepine is well known but is rarely mentioned in the geriatric literature, probably because the drug's primary indication is in the treatment of epilepsy, a condition that usually presents in younger patients, who rarely have concomitant hypertension, but carbamazepine has many other indications, such as for bipolar disorder, withdrawal procedures, and neuropathic pain, and its use has become more frequent, including in geriatric populations, in spite of the risk of interactions, or the risk of hepatic, cutaneus, and hematological toxicities. Carbamazepine is consequently not recommended for use in elderly patients, and an alternative treatment should be considered. Gabapentin, alone or in combination with clonazepam, should be tried for neuropathic pain,8,9 and antidepressants (tricyclics), topical anaesthetic agents, opiates, and analgesics could also be considered.10,11 Conflict of Interest: The editor in chief has reviewed the conflict of interest checklist provided by the authors and has determined that the authors have no financial or any other kind of personal conflicts with this letter. Author Contributions: Emilia Frangos Lordos and Véronique Trombert: preparation of manuscript, acquisition of subject, interpretation of data. Nicole Vogt: revision of manuscript. Jean-Jacques Perrenoud: Revision of manuscript, supervision. Sponsor's Role: None.

Kosulys ir rūkymas

Kosulys – svarbus kvėpavimo sistemos apsauginis refleksas. Kosuliu skundžiasi 9–33 proc. Europos ir JAV gyventojų. Kosulys yra vienas dažniausių simptomų, dėl kurių pacientai kreipiasi į gydytoją. Vaistams nuo kosulio, nepaisant jų dalinio efektyvumo, išleidžiama šimtai milijardų dolerių. Taigi kosulio problema aktuali ne tik medicininiu, bet ir socialiniu bei ekonominiu požiūriu. Rūkymas yra vienas svarbiausių išvengiamų kvėpavimo ligų rizikos veiksnių. Rūkymas sumažina sveikų asmenų kosulio reflekso jautrumą, bet jis normalizuojasi jiems metus rūkyti. Sergančių LOPL rūkorių ir sergančių LOPL buvusių rūkorių kosulio reflekso jautrumas nesiskiria.

Relation et dépendance dans un service de dialyse

Dialysis substitutes a deficient organ. To perform dialysis requires qualified nurses and physicians, necessitates time and is an expensive procedure. In a society which valorises autonomy, dialysis leads to dependency and therefore is associated with a very bad image. This loss of autonomy is one of the most common complains of dialyzed patients. For this reason, patients and caregivers valorise renal transplantation. It illustrates how the concept of autonomy and dependency may influence the life experience of dialyzed patients. We propose another approach which is oriented to the aspects of relations during dialysis. This approach is illustrated by two case reports. This concept allows to change the perception of the dialyzed patient and thus to change his life experience.

Unusual Clinical Presentations of Vestibular Schwannomas

The aim of this study is evaluate the unusual ways of initial presentation of the vestibular schwannomas. We performed a retrospective study of the patients who underwent resection of acoustic neuromas on our service, including for analysis only the cases which initial symptom was not the hearing loss. Tumor size, localization, clinical presentation, and age of the patients were considered. Nine patients present with atypical symptoms. The most common complain in this group were facial paresthesias (22,2 %). None of them complained about other otological symptoms. A significant group of patients did not present with the otological symptoms classically associated with vestibular schwannoma. Clinical knowledge of these kinds of symptoms may lead to earlier detection of these lesions.

Anterior knee pain

Anterior knee pain is a common complain in all ages athletes. It may be caused by a large variety of injuries. There is a continuum of diagnoses and most of the disorders are closely related. Repeated minor trauma and overuse play an important role for the development of lesions in Hoffa's pad, extensor mechanism, lateral and medial restrain structures or cartilage surface, however usually an increase or change of activity is referred. Although the direct relation of cartilage lesions, especially chondral, and pain is a subject of debate these lesions may be responsible of early osteoarthrosis and can determine athlete's prognosis. The anatomy and biomechanics of patellofemoral joint is complex and symptoms are often unspecific. Transient patellar dislocation has MR distinct features that provide evidence of prior dislocation and rules our complication. However, anterior knee pain more often is related to overuse and repeated minor trauma. Patella and quadriceps tendon have been also implicated in anterior knee pain, as well as lateral or medial restraint structures and Hoffa's pad. US and MR are excellent tools for the diagnosis of superficial tendons, the advantage of MR is that permits to rule out other sources of intraarticular derangements. Due to the complex anatomy and biomechanic of patellofemoral joint maltracking is not fully understood; plain films and CT allow the study of malalignment, new CT and MR kinematic studies have promising results but further studies are needed. Our purpose here is to describe how imaging techniques can be helpful in precisely defining the origin of the patient's complaint and thus improve understanding and management of these injuries.

Cutaneous and Ocular Late Complications of Sulfur Mustard in Iranian Veterans

Although sulfur mustard (SM) has been used as a chemical warfare agent since the early twentieth century, it has reemerged in the past decade as a major threat around the world. This agent injured over 100,000 Iranians and one-third is suffering from late effects until today. Mustard affects many organs such as the skin, eyes, and lungs, as well as the gastrointestinal, endocrine, and hematopoietic system.In this study we focused on review of the late Cutaneous and ocular complications caused by exposure to SM.All studies regarding long-term ocular and cutaneous effects, which have been done on Iranian population, were collected from domestic and international sources. Pruritus is the most common complain and a malignant change is the most important lesion, which has to be considered. Also this agent is causes of chronic and delayed destructive lesions in the ocular surface and cornea, leading to progressive visual deterioration and ocular irritation.

Tuberculose endobrônquica – alterações clínicas e broncoscópicas

Endobronchial tuberculosis (ET) is a serious complication of pulmonary tuberculosis and is a major cause of morbidity. The aim of our retrospective study was to characterize the clinical, radiological, microbiological and bronchoscopic features of ET. Between January 1999 and June 2002 a total of 14 patients were diagnosed as having ET in our hospital. There were 8 (57%) men and 6 women with a median age of 39.6 +/- 18.1 years (range from 20 to 78 years). Cough was the most common complain and it was present in 71.4% of patients. Only 5 patients were sputum smear positive. Five patients (35.7%) had parenchymal infiltration and this was the most common roentgenographic appearance. Forms of ET were classified into subtypes: actively caseating (n=4), granular (n=3), tumorous (n=3), edematous-hyperemic (n=2) and ulcerative (n=2). The upper lobes were affected in 9 (64.3%) patients. Nine patients had involvement of the left bronchial tree, 3 of the right and in 2 there were bilateral lesions. The diagnosis could be established in 11 (78.6%) cases by bronchial biopsy. All patients had positive bronchial lavage cultures for acid-fast bacilli. Clinical manifestations and roentgenographic appearance of ET are not specific and so bronchoscopy is mandatory for the prompt diagnosis and follow-up of its evolution.

Prognóstico de tumores testiculares germinativos

OBJETIVO: Investigar as características e a evolução de homens adultos portadores de tumores germinativos do testículo. MÉTODOS: Estudamos as características e a evolução 29 pacientes tratados (14 seminomas e 15 não seminomas). O tempo médio de seguimento foi de 56 meses para os seminomas e de 40 meses para os não seminomatosos. Todos foram submetidos a orquiectomia. Nos estádios II e III associou-se radioterapia para os seminomas, e quimioterapia e linfadenectomia para os não seminomatosos. RESULTADOS: As queixas mais freqüentes foram aumento de volume testicular (57%) e dor (30%). Nos seminomas a idade média foi de 41,2 anos e nos não seminomas foi de 29,2 anos. Antecedente de criptorquidia foi assinalada em 28,5% dos seminomas e em 15,5% dos não seminomatosos. As proporções respectivas de estádios I, II e III foram de 79%, 14% e 7% em seminomas, e 40%, 27% e 33% em não seminomas. Os seminomas não provocaram elevação dos marcadores AFP ou b-HCG enquanto os não seminomatosos elevaram esses marcadores respectivamente em 46,6% e 33,3% dos casos. Morte pela doença ocorreu em 1 caso de seminoma e 3 de não seminomas, mas não houve diferença na sobrevida entre os grupos. CONCLUSÃO: A criptorquidia continua sendo um fator predisponente importante na etiologia dos tumores germinativos. Apesar dos tumores não seminomatosos se apresentarem em estádios mais avançados a sobrevida dos pacientes não difere da apresentada pelos portadores de seminomas.

STUDIES ON 30 CASES OF FEMORAL HERNIA

A series of 30 cases of femoral hernia which were operated on at the hospital in a recent 12-year period were clinically studied. There were 28 women and two men with a mean age of 73.2 years old. Swelling of the inguinal portion was the most common complain seen in 23 patients, followed by symptom of ileus in four patients and another symptoms in three patients. There were 18 patients with right femoral hernia, 10 patients with left femoral herunia and two patients with bilateral femoral hernia. All cases were diagnosed by physical examination. The diagnosis was made by palpation of the inguinal portion in the three patients with another symptoms and in the lateral lesion of two patients with bilateral femoral hernia. Incarceration occured in five patients (16.7%) who underwent an emergency operations. Of these five patients, two patients demanded resection of the intestine because of necrosis of the small intestine. Post operative complication occured in one out of the two resected patients whose wound healing delayed. Mean postoperative hospital stay in the incarcerated cases was longer than that in the non-incarcerated cases. We should make efforts to prevent the patients who are often elderly women from incarcerating of the hernia by careful routine medical examinations.

Common complaints of the elderly.

What happens when geriatric patients have unlimited access to sympathetic physicians? For one thing, they seldom come in without a good reason, though perhaps not the one they give. Common complain...

PROSTATE CANCER MANAGEMENT IN MOEWARDI HOSPITAL SURAKARTA FROM JANUARY 2000 – DECEMBER 2006

Objective: To describe the prostate cancer management in Dr. Moewardi Hospital Surakarta on January 2000 – December 2006. Materials & Methods: This study is a retrospective descriptive. The data was collected from Dr. Moewardi Hospital Surakarta’s medical record in seven years, from January 2000 to December 2006. Results: We found that thirty patients with prostate cancer with age above 50 years and mostly found on age 71 – 75 years (23,3%). The most common complain that can be found are LUTS (76,7%). Malignancies was found on digital rectal examination on 76,7% patients. About 28 patients with PSA level > 4ng. Most of the patients (20/66,7%) comes with T2 stadium and seven of them (23,3%) with metastize to the pelvic bone. All of the patient was administered with TUR-P, 7 patients with metastize administered to orchidectomy and hormonal therapy (23,3%), and only one of them continued with radiotheraphy. All of the prostate materials that analyze on pathyologic examination are adenocarcinoma of the prostate with 50% speciments are poorly differentiated. Conclusion: From thirty patients diagnozed with prostate cancer, most of them was found between 71 – 75 years old. The common complain are urinary retention, LUTS and pelvic bone metastize. The pathologic examination we shows all of the speciments are adenocarcinoma of the prostate and they are poorly differentiated.

Reproductive Health and Nutritional Status of Girl Students in an Urban Area of Bangladesh

Objectives: To assess status of reproductive health and nutrition amongst girls attending high school in an urban area of Bangladesh. Methods: This cross sectional descriptive study was conducted in four selected girl's high schools. A structured pre-tested questionnaire and a checklist were used to collect data through face-to-face interview and anthropometry. Results: A total of 360 adolescents girls were interviewed. The mean age at menarche of the respondents was found to be 12.4 years. More than half (54.2%) of the respondents were malnourished (BMI < 18.5). More than four-fifths (83%) were found to be suffering from reproductive health problems during or after menstruation. The most common complain (60%) disclosed by the adolescent girls was dysmenorrhoea. Majority (300) of the respondents acknowledged practicing unhygienic protective measures during menstruation. Conclusion: More than half of the adolescents were malnourished, practiced unhygienic protective measures during menstruation and disclosed different types of reproductive health complaints. Findings of the study strongly recommend that adolescent girls of urban Bangladesh need proper and appropriate management of their reproductive health problems. Ibrahim Med. Coll. J. 2008; 2(1): 9-11 Key words: Nutritional Status, Reproductive Health, Adolescence. doi: 10.3329/imcj.v2i1.2924