Abstract Analysis of very high signal-to-noise ratio (S/N) spectra of reddened stars allowed us to determine an upper limit (UL) of the column density N(C4). We developed a robust calibration of the N(C4) based on the C4 gas-phase spectrum profile at 3789 Å. The UL of the column density can be calculated using the equation N UL(C4) = 8.963 × 1015/(S/N), where S/N is in the wavelength range ∼3790 Å. Nondetection of this molecule was confirmed in stars exhibiting a high abundance of C2 and C3 molecules. According to our calibration, assuming an optimistic estimate of the ratio N ( C 3 ) N ( C 4 ) = 10, even for the star HD 147889 with the highest known to date column density of C3, the S/N required for detecting the C4 molecule is about 12,000 per pixel, which is a challenging task. Despite this tough conclusion regarding the possibility of detecting the interstellar molecule C4, we also tried to find a link between known lines of C5 at 4975 and 5109 Å and weak interstellar features. The expected C5 4975 Å feature coincides well with weak diffuse interstellar band (DIB) 4975, while the search for the 5109 Å C5 band is badly conditioned by the overlap with a broad spectral feature, which is a blend of stellar and interstellar lines. However, we found a rather good correlation between the equivalent width of DIB 4975 and N(C2), making the search for C5 not hopeless. If DIB 4975 is formed by C5, its column density is only 2 times lower than that of C3.
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