Class Of Poly Research Articles

Poly(terphenylene) anion exchange membranes with high conductivity and low vanadium permeability for vanadium redox flow batteries (VRFBs)

In this study, we demonstrate a new class of poly(terphenylene) based anion exchange membranes (AEMs) with improved chemical stability and anion conductivity in vanadium redox flow batteries (VRFBs). A series of terphenyl- and biphenyl-based polymers with pendant quaternary ammonium alkyl groups were synthesized and characterized for VRFB applications. When the arrangement of the polymer backbone and cation-tethered alkyl chains was varied, the prepared AEM membranes exhibited extremely low vanadium permeance while maintaining high conductivity. These properties further provided a high coulombic efficiency close to 100% at all current densities as well as high voltage efficiency. The single cell VRFB performance with the poly(terphenylene) based AEMs showed 2–5% higher coulombic efficiency than those of commercial AEMs and similar voltage efficiency to those of commercial PEMs (Nafion® 212). The highest EE value of 93.64% was achieved at the current density of 20 mA/cm2 (vs. 72% EE for Nafion212). In addition, poly(terphenylene) based AEMs showed superior cycle stability and high capacity retention, thus demonstrating their high performance as promising IEMs for VRFB application.

Design and assessment of a novel poly(urethane-semicarbazides) containing thiadiazoles on the backbone of the polymers as inhibitors for steel pipelines corrosion in CO2-saturated oilfield water

Abstract In this investigation, a novel class of poly(urethane-semicarbazides) containing thiadiazoles on the backbone of the polymers (SR-16 and SR-17) was synthesized and characterized by different spectroscopic methods (FTIR, 1H NMR, and 13C NMR). The inhibition action of the synthesized polymers on steel pipelines in carbon dioxide-containing oilfield formation water has been studied using electrochemical measurements namely, electrochemical impedance spectroscopy (EIS), potentiodynamic polarization (PDP), and surface morphology tools such as energy-dispersive spectroscopy (EDX) and a field emission-scanning electron microscopy (FE-SEM). The findings indicate that the fabricated polymers SR-16 and SR-17 exhibits superior corrosion performance on steel in oilfield formation water saturated with CO2. The protection capacity is found to increase by increasing the polymer concentration up to maximum values 92.12 and 96.52% for 150 ppm at 50 °C in the presence of SR-16 and SR-17, respectively. The FE-SEM and EDX measurements indicate that the steel surface is protected by studied polymers. The current study provides very significative data in fabricating and designing novel polymer inhibitors with high protection efficiency.

Development of an HKUST-1 Nanofiller-Templated Poly(ether sulfone) Mixed Matrix Membrane for a Highly Efficient Ultrafiltration Process.

Mixed-matrix membranes (MMMs) have been drawing increasing attention due to the high permeability and high rejection capabilities for highly efficient wastewater treatment applications. Nonetheless, improving the water permeance while maintaining the high rejection capability is still an ongoing challenge for the practically state-of-the-art MMMs. Herein, a new class of poly(ether sulfone) (PES) based MMM containing metal-organic framework (MOF) nanofillers of HKUST-1 and blending with poly(methyl methacrylate- co-methacrylic acid) (PMMA- co-MAA) copolymer, designated as HKUST-1@mPES MMM, were developed for the highly efficient ultrafiltration (UF) process. In this study, the nanosized HKUST-1 nanofillers were removed by water dissolution as sacrificial templating materials, so that the additional nanovoids were deliberately generated throughout the dense polymer matrix. The introduction of PMMA- co-MAA copolymer facilitated the even dispersion of HKUST-1 nanofillers in a polymer matrix, by constructing the bridge connection between inorganic nanofillers and organic matrix. The resultant HKUST-1@mPES MMM exhibited a high pure water permeability (PWP) up to 490 L·m-2·h-1·bar-1, substantially reaching nearly 3 times higher than that of the mPES membrane without HKUST-1 nanofillers loading and maintaining a relatively high BSA rejection rate of 96% without obvious deterioration. The newly developed HKUST-1@mPES MMM thereby exhibited a comparable separation efficiency compared to the cutting-edge UF membranes reported so far. Overall, the nanovoid-generated approach provides new insight into developing advanced MMMs used for highly efficient water treatment applications.

KOMPOSISI JENIS DAN STRUKTUR VEGETASI HUTAN DATARAN RENDAH DI KOMPLEKS GUNUNG BULUSARAUNG SULAWESI SELATAN

The Bulusaraung Mountain is a lowland forest and is one of the main ecosystems owned by Bantimurung Bulusaraung National Park. Therefore, this study aims to determine the species composition and vegetation structure of lowland forests in the complex of Bulusaraung Mountain. The research was conducted from April to May 2018. Data collection was carried out using a 20 × 20 meter plot placed on the Balleanging, Tokaddaro and Tompobulu track lines based on altitude (550 m asl, 650 m asl, and 750 m asl). The result of this study show that there are 44 species were found on tree class, 65 species on pole class, 40 species on sapling class and 25 species on seedling class. The species composition in the study area was dominated Palaquium obovatum, Persea rimosa, Arthrophyllum diversifolium, Cryptocarya laevigata, and Engelhardia serrata, while Psychotria leptothyrsa, Antidesma bunius, Maesa ramentacea, Ficus sandpaper, Baccaurea javanica, Symplocos maliliency, Callicarpa pentandra, and Saurauia tristyla is a type of tree that differentiates at each altitude. The structure of the forest canopy layer at an altitude of 550 m above sea level consists of three canopy layers, while at an altitude of 650 and 750 m above sea level consisting only of two canopy layers. The cover of forest canopy in all sampling locations was reached 75-90%.

Multi-dimensional wind fragility functions for wood utility poles

Risk assessment and life cycle cost analysis of electric power systems facilitate analysis and efficient management of compound risks from wind hazards and asset deteriorations. Fragility functions are key components for these analyses as they provide the probability of failure of poles given the hazard intensity. Despite a number of efforts that analyzed the wind fragility of utility wood poles, impacts of key design variables on the likelihood of failure of poles have not been yet characterized. This paper, for the first time, provides a set of multi-dimensional fragility models that are functions of key factors including class, age, and height of poles, number and diameter of conductors, span length, and wind speed and direction. Unlike existing generic pole fragility models, this new class of fragility functions is able to accurately represent various configurations of power distribution systems. Therefore, it can reliably support decisions for installation of new or replacement of existing damaged or decayed poles. The generated fragility models are also used to investigate impacts of design variables. For example, results indicate that when height is considered as a covariate for the fragility function, the likelihood of failure of wood poles for a given height increases with class number. However, if height is treated as an uncertain variable, and therefore, excluded as a covariate from the fragility model, lower classes of poles may have higher failure probability as they are often used for higher clearance limits.

Development of deep learning architecture for automatic classification of outdoor mobile LiDAR data

ABSTRACTThis paper proposes a deep convolutional neural network (CNN) architecture for automatic classification of mobile laser scanning (MLS) data obtained for outdoor environment, which are characterized by noise, clutter, large size and larger quantum of information. The developed architecture introduces a look up table (LUT) based approach, which retains the geometry of the input MLS point cloud while rescaling. Further, with the voxelisation of the input MLS sample, the ambiguity of selecting one out of multiple point values within a voxel is resolved. The performance of the architecture is evaluated on MLS data of outdoor environment in two instances, first using tree and non-tree classes (non-tree class has objects like electric pole, wire, low vegetation, wall, house and ground) and then with tree and electric pole classes. Additional testing is carried out by mixing the outdoor MLS data of tree and electric pole classes with three classes of indoor objects, taken from Modelnet dataset, thereby assessing the architecture efficacy over an ensemble of three-dimensional (3D) datasets. Classification of tree and non-tree classes, followed by tree and electric pole classes from MLS samples result in total accuracies of 86.0%, 90.0% respectively and kappa values of 72.0%, 78.7% respectively. Moreover, for the combinations of MLS and Modelnet classes, the classification results are promising, reaching a total accuracy of 95.2% and kappa of 92.5%. The LUT based approach has shown better classification over the traditional rescaling approach for the MLS dataset, resulting in an enhancement up to 9.0% and 18.0% in total accuracy and kappa, respectively. With different varieties of tree, non-tree and electric pole samples, the proposed architecture has shown its potential for automatic classification of MLS data with high accuracy. This study further reveals that the accuracy of classification is improved by introducing more spatial features in the input layer. The accuracies produced in this work can be further improved with the availability of better hardware resources.

Vanillin derived a carbonate dialdehyde and a carbonate diol: novel platform monomers for sustainable polymers synthesis.

Vanillin has been regarded as one of the important biomass-based platform chemicals for aromatic polymers synthesis. Herein, novel symmetric bis(4-formyl-2-methoxyphenyl)carbonate (BFMC) and bis(4-(hydroxymethyl)-2-methoxyphenyl)carbonate (BHMC) polymeric monomers have been synthesized in high yields using vanillin as a raw chemical, which have been submitted for polymer synthesis via well-established polymeric strategies. A new class of poly(carbonate ester)s oligomers with amide moieties in their side chain can be prepared by using the BFMC as one of monomers via the Passerini three compound reaction (3CR). A new class of poly(carbonate ester)s oligomers and poly(carbonate urethane)s can be prepared via reactions between BHMC with dicarboxylic acid chlorides and diisocyanates, respectively. Their structure have been confirmed by 1H NMR, 13C NMR and FTIR, and the gel permeation chromatograph (GPC) analysis shows that the Mn of poly(carbonate ester)s oligomers ranges from 3100 to 7900 with PDI between 1.31 and 1.65, and the Mn of poly(carbonate urethane)s ranges from 16 400 to 24 400 with PDI ranging from 1.36 to 2.17. The DSC analysis shows that the poly(carbonate ester)s oligomers have relative low Tg ranging from 37.4 to 74.1 °C, and the poly(carbonate urethane)s have Tg ranging from 97.3 to 138.3 °C, mainly correlating to the structure of dicarboxylic acid chlorides and diisocyanates used.

Synthesis and characterization of CO2-sensitive temperature-responsive catalytic poly(ionic liquid) microgels

A class of poly(ionic liquid) microgels exhibiting CO2-switchable temperature-responsive volume phase transition behavior have been synthesized and used for CO2 fixation.

Synthesis and characterization of poly(ether sulfone) block copolymers containing pendent quaternary ammonium- and imidazolium groups as anion exchange membranes

A class of poly(ether sulfone) (FPES) block copolymers containing pendent quaternary ammonium (QA) and imidazolium (IM) groups were prepared as anion exchange membranes by reaction involving nucleophilic substitution, benzylic bromination, quaternization and anion exchange with hydroxide ions. Highly reactive hexafluorobenzene (HFB) was utilized as a linkage group for relatively low temperature (e.g., 105°C) coupling between hydrophobic and precursor hydrophilic oligomer blocks. The phase separated morphology, water uptake, swelling ratio, conductivity, and chemical stability of the resultant copolymer membranes were also investigated. The hydroxide conductivity of the ionomer membranes (IEC~2.0 mequiv./g) was 21–22mS/cm and 56–63mS/cm at 30°C and 80°C respectively. The FPES-IM membrane showed relatively very good dimensional integrity in high pH solution, whereas under the similar condition the FPES-QA membrane broke into pieces. However, the degradation of the imidazolium cations in FPES-IM was relatively faster in comparison to the ammonium cations in FPES-QA.

Preparation and characterization of a new class of poly(ether‐block‐amide)s via solvent free reactive processing

Novel poly(ether‐co‐amide) block copolymers (PEA) with polyamide‐6 as hard segments and different polyether (polyoxytetramethylene glycol [PTMG]/polyethylene glycol [PEG]) as soft segments were prepared via reactive processing. The chemical structure, crystalline properties, mechanical properties, water resistance, and thermal stability of as‐prepared PEAs were extensively studied by Fourier transform infrared spectroscopy, X‐ray diffraction, differential scanning calorimetry, dynamic mechanical analysis, tensile testing, water contact angle, water absorption, and thermal gravity analysis. Fourier transform infrared spectroscopy confirmed the chemical structure and composition of PEAs. The X‐ray diffraction and differential scanning calorimetry showed that PEAs consist of obvious crystalline polyamide‐6 hard segments and that the crystalline structure of PEG will be significantly changed with the addition of PTMG. Dynamic mechanical analysis and tensile testing showed that the obtained PEAs exhibit classical elastomeric rubber plateau and tensile behavior. Meanwhile, the introduction of PTMG will improve the mechanical properties of PEAs. PEA with PEG as soft segments exhibited extremely surface hydrophilicity and high water absorption of 127%; the increasing of PTMG content in soft segments will reduce the surface hydrophilicity and improve the water resistance. In addition, the obtained PEAs exhibited good thermal stability, which will meet requirement of multiple processing.

Synthesis and properties of poly(arylene ether nitrile) with pendant bisulfonic acid for proton exchange membrane application

A new class of poly(arylene ether nitrile) with a bisulfonated phenyl ring on the side chains (PAEN-bS) was prepared from a hydroxybenyl-containing polymer precursor and a bisulfonated monomer by a...

Novel poly(ADP-ribose) polymerase inhibitor veliparib: biophysical studies on its binding to calf thymus DNA

Veliparib, an new anticancer drug in the class of poly (ADP-ribose) polymerase inhibitors, intercalates partially and binds to ctDNA and induces moderate conformational perturbation of the DNA.

Development of l-Tyrosine-Based Enzyme-Responsive Amphiphilic Poly(ester-urethane) Nanocarriers for Multiple Drug Delivery to Cancer Cells.

New classes of enzymatic-biodegradable amphiphilic poly(ester-urethane)s were designed and developed from l-tyrosine amino acid resources and their self-assembled nanoparticles were employed as multiple drug delivery vehicles in cancer therapy. The amine and carboxylic acid functional groups in l-tyrosine were converted into dual functional ester-urethane monomers and they were subjected to solvent free melt polycondensation with hydrophilic polyethylene glycols to produce comb-type poly(ester-urethane)s. The phenolic unit in the l-tyrosine was anchored with hydrophobic alkyl side chain to bring appropriate amphiphilicity in the polymer geometry to self-assemble them as stable nanoscaffolds in aqueous medium. The topology of the polymer was found to play a major role on the glass transition, crystallinity, and viscoelastic rheological properties of l-tyrosine poly(ester-urethane)s. The amphiphilic polymers were self-assembled as 200 ± 10 nm nanoparticles and they exhibited excellent encapsulation capabilities for anticancer drugs such as doxorubicin (DOX) and camptothecin (CPT). In vitro drug release studies revealed that the drug-loaded l-tyrosine nanoparticles were stable at extracellular conditions and they underwent enzymatic-biodegradation exclusively at the intracellular level to release the drugs. Cytotoxicity studies in the cervical cancer (HeLa) and normal WT-MEFs cell lines revealed that the nascent l-tyrosine nanoparticles were nontoxic, whereas the CPT and DOX drug-loaded polymer nanoparticles exhibited excellent cell killing in cancer cells. Confocal microscopic imaging confirmed the cellular internalization of drug-loaded nanoparticles. The drugs were taken up by the cells much higher quantity while delivering them from l-tyrosine nanoparticle platform compared to their free state. Flow cytometry analysis showed that the DOX-loaded polymer nanoscaffolds internalized the drugs 8-10× higher compared to free DOX. Both the synthesis of new classes of poly(ester-urethane)s via melt polycondensation approach and the enzyme-responsive drug delivery concept were accomplished for the first time. Thus, the present investigation is expected to open up new opportunities for l-tyrosine polymeric materials in biomaterial and thermoplastic applications.

Enhanced Ionic Conductivity of a 1,2,3-Triazolium-Based Poly(siloxane ionic liquid) Homopolymer.

A 1,2,3-triazolium-based poly(siloxane ionic liquid) (PSIL) is synthesized by UV-triggered thiol-ene ligation between a poly[(mercaptopropyl)methylsiloxane] and a tailor-made vinyl-functionalized triethylene glycol-based 1,2,3-triazolium ionic liquid. The quantitative nature of the thiol-ene coupling is demonstrated by 1H and 13C NMR, whereas properties of this new PSIL are discussed based on solubility, size exclusion chromatography, differential scanning calorimetry, thermogravimetric analysis, and broadband dielectric spectroscopy measurements. Besides exhibiting low glass transition temperature (Tg = -62 °C) and high thermal stability (Td10 = 284 °C), this new class of poly(1,2,3-triazolium) demonstrates the highest value of bulk anhydrous ionic conductivity reported to date for PILs (σDC = 7 × 10-5 S cm-1 at 30 °C).

Absorption of SO2(g) by TDAE[O2SSO2](s) to Give TDAE[O2SS(O)2SO2](s): Related Reactions of [NR4]2[O2SSO2](s) (R = CH3, C2H5).

One mole equivalent of gaseous SO2 is absorbed by purple TDAE[O2SSO2](s), producing red, essentially spectroscopically pure TDAE[O2SS(O)2SO2](s); under prolonged evacuation, the product loses SO2(g), regenerating TDAE[O2SSO2](s). Similarly, [NR4]2[O2SS(O)2SO2](s) (R = Et, Me) can be prepared, albeit at lower purity, from the corresponding tetraalkylammonium dithionites (prepared by a modification of the known [NEt4]2[O2SSO2](s) preparation). While the [NEt4](+) salt is stable at rt; the [NMe4](+) salt has only limited stability at -78 °C. Vibrational spectra assignments for the anion in these salts were distinctly different from those for the anion in salts containing the long-known [O3SSSO3](2-) dianion, the most thermodynamically stable form of [S3O6](2-) (we prepared TDAE[O3SSSO3]·H2O(s) and obtained its structure by X-ray diffraction and vibrational analyses). The best fit between the calculated ((B3PW91/6-311+G(3df) and PBE0/6-311G(d)) and experimental vibrational spectra were obtained with the dianion having the [O2SS(O)2SO2](2-) structure. Vibrational analyses of the three [O2SS(O)2SO2](2-) salts prepared in this work showed that the corresponding [O3SSO2](2-) salts were present as a ubiquitous decomposition product. The formation of these new [O2SS(O)2SO2](2-) dianion salts was predicted to be favorable for [NMe4](+) and larger cations using a combination of theoretical calculations (B3PW91/6-311+G(3df)) and volume based thermodynamics (VBT). Similar methods accounted for the greater stabilities of the TDAE(2+) and [NEt4](+) salts of [O2SS(O)2SO2](2-) compared to [NMe4]2[O2SS(O)2SO2](s) toward irreversible decomposition to the corresponding [O3SSO2](2-) salts. These salts represent the first known examples of a new class of poly(sulfur dioxide) dianion, [SO2]n(2-) in which n > 2.

Surface functionalization superparamagnetic nanoparticles conjugated with thermoresponsive poly(epsilon-lysine) dendrons tethered with carboxybetaine for the mild hyperthermia-controlled delivery of VEGF

Vascular endothelial growth factor (VEGF) is the growth factor responsible for the triggering of angiogenesis, the process of blood vessel formation supporting the long-term viability of any repaired or regenerated tissue. As the growth factor is effective only when concentration gradients are generated, new shuttles need to be developed that ensure both the control of gradients at the site of tissue repair and the release of VEGF at physiological levels. Magnetic hyperthermia is the production of heat induced by magnetic materials through their exposure to an external oscillating magnetic field. In this paper, magnetic nanoparticles capable of generating controllable hyperthermia were functionalised with hyperbranched poly(epsilon-lysine) peptides integrating in their core parallel thermoresponsive elastin-like peptide sequences and presenting an uppermost branching generation tethered by the zwitterionic amino acid carboxybetaine. The results show that these functionalised magnetic nanoparticles avidly bind VEGF and release it only upon generation of mild-hyperthermic pulses generated by oscillating magnetic filed. The VEGF release occurred in a temperature range at which the elastin-like peptides collapse. It is proposed that, through the application of an external magnetic field, these magnetic carriers could generated gradients of VEGF in vivo and allow its tuned delivery in a number of clinical applications. Statement of SignificanceThe present paper for the first time reveals the possibility to control the delivery of VEGF through mild hyperthermia stimuli generated by a oscillating magnetic field. To this purpose, magnetic nanoparticles of high size homogeneity and coated with a thin coating of poly(acrylic acid) were functionalised with a novel class of poly(epsilon lysine) dendrimers integrating in their structure a thermoresponsive amino acid sequence mimicking elastin and exposing at high density a zwitterionic modified amino acid, the carboxybetaine, known to be able to bind macromolecules. Physicochemical and biochemical characterisation elegantly show the link between the thermal properties of the nanoparticles and of the dendrimer change of conformation and how this enable the release of VEGF at temperature values compatible with the growth factor stability.

A Pronounced Halogen Effect on the Organogelation Properties of Peripherally Halogen Functionalized Poly(benzyl ether) Dendrons.

An interesting halogen-substituent effect on the organogelation properties of poly(benzyl ether) dendrons is reported. A new class of poly(benzyl ether) dendrons with halo substituents decorating their periphery was synthesized and fully characterized. A systematic study on the gelation abilities, thermotropic behaviors, aggregated microstructures, and mechanical properties of self-assembled organogels was performed to elucidate the halogen-substituent effects on their organogelation propensity. It was found that the exact halogen substitutions on the periphery of dendrons exert a profound effect on the organogelation propensity, and dendrons Gn -Cl (n=2, 3) and G2 -I proved to be highly efficient organogelators. The cooperation of multiple π-π, dispersive halogen, CH-π, and weak C-H⋅⋅⋅X hydrogen-bonding interactions were found to be the key contributor to forming the self-assembled gels. Dendritic organogels formed from Gn -Cl (n=2, 3) in 1,2-dichloroethane exhibited thixotropic-responsive properties, and such thixotropic organogels are promising materials for future research and applications.

Catalysts and temperature driven melt polycondensation reaction for helical poly(ester-urethane)s based on natural L-amino acids

Catalyst and temperature driven melt polycondensation reaction was developed for natural L-amino acid monomers to produce new classes of poly(ester-urethane)s. Wide ranges of catalysts from alkali, alkali earth metal, transition metal and lanthanides were developed for the condensation of amino acid monomers with diols to yield poly(ester-urethane)s. A-B Diblock and A-B-A triblock species were obtained by carefully choosing mono- or diols in model reactions. More than two dozens of transition metal and lanthanide catalysts were identified for the polycondensation to yield high molecular weight poly(ester-urethane)s. Theoretical studies revealed that the carbonyl carbon in ester possessed low electron density compared to the carbonyl carbon in urethane which driven the thermo-selective polymerization process. Optical purity of the L-amino acid residues in the melt polycondensation process was investigated using D- and L-isomers and the resultant products were analyzed by chiral-HPLC and CD spectroscopy. CD analysis revealed that the amino acid based polymers were self-assembled as β-sheet and polyproline type II secondary structures. Electron and atomic force microscopic analysis confirmed the formation of helical nano-fibrous morphology in poly(ester-urethane)s. The newly developed melt polycondensation process is very efficient and optimized for wide range of catalysts to produce diverse polymer structures from natural L-amino acids. © 2015 Wiley Periodicals, Inc. J. Polym. Sci., Part A: Polym. Chem. 2015

MRI virtual biopsy and treatment of brain metastatic tumors with targeted nanobioconjugates: nanoclinic in the brain.

Differential diagnosis of brain magnetic resonance imaging (MRI) enhancement(s) remains a significant problem, which may be difficult to resolve without biopsy, which can be often dangerous or even impossible. Such MRI enhancement(s) can result from metastasis of primary tumors such as lung or breast, radiation necrosis, infections, or a new primary brain tumor (glioma, meningioma). Neurological symptoms are often the same on initial presentation. To develop a more precise noninvasive MRI diagnostic method, we have engineered a new class of poly(β-l-malic acid) polymeric nanoimaging agents (NIAs). The NIAs carrying attached MRI tracer are able to pass through the blood-brain barrier (BBB) and specifically target cancer cells for efficient imaging. A qualitative/quantitative "MRI virtual biopsy" method is based on a nanoconjugate carrying MRI contrast agent gadolinium-DOTA and antibodies recognizing tumor-specific markers and extravasating through the BBB. In newly developed double tumor xenogeneic mouse models of brain metastasis this noninvasive method allowed differential diagnosis of HER2- and EGFR-expressing brain tumors. After MRI diagnosis, breast and lung cancer brain metastases were successfully treated with similar tumor-targeted nanoconjugates carrying molecular inhibitors of EGFR or HER2 instead of imaging contrast agent. The treatment resulted in a significant increase in animal survival and markedly reduced immunostaining for several cancer stem cell markers. Novel NIAs could be useful for brain diagnostic MRI in the clinic without currently performed brain biopsies. This technology shows promise for differential MRI diagnosis and treatment of brain metastases and other pathologies when biopsies are difficult to perform.

Electrochemical characterization of a responsive macromolecular interface on gold

This study reports on the investigation of a thermo­responsive polymer as a thin film on electrodes and the influence of coupling a peptide and an antibody to the film. The utilized polymer from the class of poly(oligoethylene glycol)‐methacrylate polymers (poly(OEGMA)) with carboxy functions containing side chains was synthesized and properly characterized in aqueous solutions. The dependence of the cloud point on the pH of the surrounding media is discussed. The responsive polymer was immobilized on gold electrodes as shown by electrochemical, quartz crystal microbalance (QCM), and atomic force microscopy (AFM) techniques. The temperature dependent behavior of the polymer covalently grafted to gold substrates is investigated using cyclic voltammetry (CV) in ferro‐/ferricyanide solution. Significant changes in the slope of the temperature‐de­pendence of the voltammetric peak current and the peak separation values clearly indicate the thermally induced conformational change on the surface. Finally, a bio­recognition reaction between a short FLAG peptide (N‐Asp‐Tyr‐Lys‐Asp‐Asp‐Asp‐Asp‐Lys‐C) covalently im­mobilized on the polymer interface and the corresponding IgG antibody was performed. The study shows that the responsiveness of the electrode is retained after peptide coupling and antibody binding, although the response is diminished.