Chorioallantoic Cavity Research Articles

インフルエンザ・ウイルスの赤血球凝集能と感染能及免疫能との関連性

We studied the hemagglutinating activity, infectivity and immunizing ability of influenza virus FM1 (egg-adapted strain and mouse-adapted strain). The mouse-adapted strain FM1 had infectivity, immunizing ability and toxicity against chick embryo proportion to its hemagglutinating activity, but not against mice.After we repeated the adsorption of virus in virus-suspension with chick red cells, we inoculated the 10-1-10-5 dilution of that non-hemagglutinating supernatant into the chorioallantoic cavity of eggs, and, after 48 hours' incubation, we recognized the virus-production by their hemagglutination. So that there may be the non-hemagglutinating but infective influenza virus.

孵化鷄卵内に於けるウィルスの干渉現象

I have studied the interference phenomena between Influenza virus and several viruses including Japanese B Encephalitis in chick embryo system. When several strains of Influenza virus were inoculated into the chorio-allantoic cavity of an embryonated egg, inoculated 72 hours previously with Japanese B Encephalitis virus, the Influenza virus was unable to propagate. The excluding ability of Japanese B Encephalitis virus against Influenza virus depends upon its virulence; also the interference phenomena of Japanese B Encephalitis is stronger when inoculated into the yolk sac than when into the chorioallantoic cavity.From the above experiments, with Influenza virus as the indicator the degree of propagation of the Japanese B Encephalitis virus in hatching chick embryo can be detected.