A dichloromethane extract of the aerial parts of Combretum albopunctatum Suesseng afforded five phenolic compounds—three known flavonoids and two novel cyclobutane chalcone dimers. The chemical structures were determined by standard spectroscopic techniques and the structure and relative stereochemistry of one chalcone dimer, rel-(1α,2β)-di-(2,6-dimethoxy-4-hydroxy)-benzoyl- rel-(3α,4β)-diphenylcyclobutane, were confirmed by single crystal X-ray diffraction.
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