Certainty Of Detection Research Articles

How the training of ultrasonographers influences the certainty of prenatal detection of congenital malformations of interest to the pediatric surgeon.

The training needed for doing obstetric ultrasounds is rarely reported. The aim of this study was to determine whether the training of the ultrasonographer influences the prenatal diagnostic certainty of some congenital malformations. We conducted a retrospective evaluation of antepartum sonographic findings of newborn infants found ultimately to have a congenital anomaly in a tertiary level pediatric reference center. Data were collected on admission for consecutive patients at a tertiary-level pediatric reference center. The mother´s pregnancy and birth demographic variables and those of the prenatal ultrasound (PUS) were analyzed and correlated with the final diagnosis. Sixty-seven neonates were included. All cases underwent PUS with a mean of 4.6. Prenatal diagnosis was established in 24 cases (35.8%). Thirteen surgical anomalies were detected, particularly anorectal malformation and gastroschisis. The accuracy of PUS was associated with the training of the physician performing the PUS, whereby PUS with the greatest accuracy were performed by gynecologists and maternal-fetal specialists against radiologists and general practitioners (p = 0.005). Patients without an accurate prenatal diagnosis had a greater risk of presenting comorbidities (relative risk [RR]: 1.65, p = < 0.001, 95% confidence interval [CI]: 1.299-2.106). In our setting, prenatal diagnosis of these malformations is directly determined by the training of the person performing the ultrasound.

Detection of fingerprints on moist crime evidence: A students’ activity

It may be asserted that there is no more effective deterrent to crime than the certainty of detection. Equally true is that there is no surer way to establishing identity than by fingerprints. The detection of fingerprints at the scene of crime is therefore one of the most powerful tools available in casework investigations. However, if the crime evidence is deliberately or accidentally exposed to water, the fingerprints get washed out and cannot be detected by conventional techniques. In this communication, we describe a simple experiment that enables the visualization of fingerprints on moist items.

Differential updating and morality: Is the way offenders learn from police detection associated with their personal morals?

The majority of differential deterrability research has investigated whether people differ in the extent to which a perceived threat of sanctions deters them from committing a crime. Less is known about the differential influence of criminal justice intervention on sanction threat perceptions. According to deterrence theory, however, for justice intervention to successfully deter crime, a process of perceptual updating is required. In the current study, we used panel data from German adolescents to supplement the research on differential updating. We applied fixed effects regressions to analyze whether people with weaker or stronger morals update their perceptions of detection risk differently following experiences of police detection. Our findings suggest that they do: risk perceptions increased more in adolescents with weak morals than in adolescents with strong morals when they experienced a higher certainty of detection (a higher detection rate). Combined with previous findings on differential deterrence (by personal morality), our results indicate that deterrence processes may—for individuals with weak morals—play a more critical role in the prevention of crime than previous nondifferential research has suggested.

Culturing Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) for Diagnosis and Genome Sequencing.

ObjectiveThe severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) nucleic acid detection “re-positive” phenomenon is encountered clinically. The accuracy of a viral nucleic acid test is crucial to prevent reintroduction of the virus into the community. This study evaluated the effect of virus culturing on increasing the sensitivity and specificity of real-time polymerase chain reaction (RT-PCR) detection and viral genomic sequencing.MethodsA series of tenfold dilutions of a SARS-CoV-2 viral stock were conducted and cultured for either 24 or 48 hours. The viral load of cultured samples was determined by RT-PCR. The cultured and non-cultured samples of 1x 50% tissue culture infectious dose (TCID50) were sequenced using metagenomic next-generation sequencing. The depth and coverage of SARS-CoV-2 genome were measured.ResultsThe lowest viral load detectable in a sample with RT-PCR was 0.01 TCID50. After a 24-h culture, the viral ORF 1ab and N-gene cycle threshold (CT) values were reduced by 4.4 points and 1 point, respectively. One TCID50 viral load of post 24-h culture revealed the sequence depth reached an average of 752 reads, compared with 0.15 in the nonculture; furthermore, the coverage was 99.99% while 6.42% in the nonculture.ConclusionThese results indicate that virus culturing can significantly increase the viral load, which can increase the certainty of true-positive detection of the viral nucleic acids, and improve the quality of virus genomic sequencing.

Detecting Hazel Dormice in the UK: what are we missing?

Multiple techniques can be used to detect the presence of Hazel Dormice and as a result, there is reasonable confidence that lack of detection means that dormice are probably absent. In the UK, ancient woodlands are frequently considered as the reservoir of Hazel Dormouse populations and are a usual starting point for surveys. However, we present evidence that this may be one of the most difficult habitats in which to detect the species. This is largely due to many of these woodlands being unmanaged, with a poorly developed shrub layer due to heavy shading. This reduces the probability of finding natural field signs such as nests and chewed hazel nuts. Similarly, because detection devices (nest boxes, nest tubes and footprint tunnels) are typically positioned no more than two metres from the ground for ease of study, there is an assumption that Hazel Dormice will leave the dense canopy to use them. We predict that there is a higher risk of false negatives in this habitat type and that more research is needed to provide better certainty of detection when surveying in high canopy woodland.

3D transesophageal echocardiography assists in evaluating the morphology, function, and presence of thrombi of left atrial appendage in patients with atrial fibrillation

BackgroundLeft atrial appendage (LAA) is significantly more likely to form thrombi in patients with atrial fibrillation (AFib). Two-dimensional transesophageal echocardiography (2D TEE) is considered the gold standard for assessing and studying LAA morphology and anatomy. However, 2D TEE can only visualize one plane at any given time. Real-time three-dimensional echocardiography (RT-3D TEE) imaging can preserve spatial and temporal resolution, which is a safe, accurate, and reproducible imaging modality. There are few reports of the usage of RT-3D TEE to study LAA in AFib patients. In our research, RT-3D TEE helps to provide detailed LAA information and identifying the presence or absence of thrombi from pectinate muscles in paroxysmal and long-standing AFib patients.MethodsLAA morphology was analyzed in detail by 2D TEE and RT-3D TEE in 320 patients with paroxysmal or long-standing AFib. The LAA flow pattern, as maximal LAA emptying flow velocity (LAAeV), was retrieved from 2D and 3D TEE imaging. LAA morphological parameters, spontaneous echo contrast (SEC), and thrombi were also detected by 2D and 3D TEE in all patients. In addition, LAA lobes and types were classified according to the morphology by 3D TEE, and the relationship between LAA types and the incidence of thrombi was evaluated.ResultsLong-standing AFib had greater enlargement of LAAs (orifice diameters and area), significantly more severe SEC, and a higher thrombi clot incidence rate by 3D-TEE compared with paroxysmal AFib patients (P<0.05). In addition, cauliflower morphology in long-standing AFib patients was associated with a higher LAA thrombus (OR 2.1, 95% CI: 1.1–8.5, P=0.031) and increased prevalence of SEC. Moreover, the uncertainty of thrombi detection was significantly decreased by 3D TEE compared with 2D TEE (P<0.001), and the certainty of thrombi detection by 3D TEE also decreased slightly (P=0.06).ConclusionsRT-3D TEE is a safe and real-time option for the evaluation of LAA morphology and function. Long-standing AFib has greater LAA and SEC, as well as a higher incidence of thrombi than the paroxysmal group. Cauliflower LAA type was associated with a higher prevalence of SEC and thrombi.

Incremental Value of Post Diuretic 68Ga-PSMA-11 PET-CT in Characterization of Indeterminate lLesions in Prostate Cancer.

Objective:The aim of current study is to evaluate the role of diuretic assisted 68Ga-PSMA PET-CT, on image quality and clinical interpretation of indeterminate/equivocal lesions in pre-Lasix imaging of Prostate cancer. Materials and Methods:Forty-five patients underwent baseline 68Ga-PSMA-11 scan 45-60 minutes post tracer injection followed by post Lasix study after ±15 minutes. The contrast to noise ratios (CNR), noise and SUVmax were determined for the focal uptakes in both pre and post Lasix images. All continuous variables were expressed as mean ± SD. Images were assessed by two experienced physicians in order to evaluate lesion detectability and delineations that have an impact on clinical interpretation. Results:Of total 45 patients, 12/45 (27%) showed unremarkable scan along with 33/45 (73%) showing metastases. Sixteen out of 45 (36%) of the metastatic scans showed indeterminate/equivocal lesions. In these cases, post Lasix study showed false negative findings in 7/45 (16%), better delineation of lesions 10/45 (22%), better confidence towards reporting lesions as abnormal in 5/45 (11%) with an overall 11/45 (24%) of the cases who showed increase in the number of the lesions after the Lasix study. The overall CNR was evaluated using Wilcoxon Rank test (p-value = 0.02) which suggested significant improved ratios in the post-Lasix imaging by 49.6%±24.5. There was a substantial agreement (k =0.76) between the physicians when comparing the lesion clarity and delineation in post Lasix images. The average score for physician one and two being 2.4 ±0.71 and 2.53±0.52 respectively.Conclusion: Post diuretic 68Ga-PSMA imaging at ± 15 minutes clears the unwanted activity in the urinary tract which in turn improves the contrast to noise ratios. Thus leading to decline in false positive findings, improved diagnostic certainty of physician and better detection of indeterminate lesions in 68Ga-PSMA imaging.

Rural crime and law

This paper discusses the nature and extent of rural crime and suggested solutions to rural crime; providing the author’s opinion on mandatory sentencing, increased penalties, certainty of detection, and reduction of the profit motive. Particularly, the article discusses the issues of stock theft, abalone poaching, firearms offences, traffic offences, logging protest cases, pastures protection – legal principles, proposed solutions, practical issues. The article also touches on changes in law enforcement, technology and the administration of justice, as well as police interviews with suspects, DNA, video surveillance, domestic violence issues and women in courts.&#x0D; The paper concludes with a description of the experiences of a magistrate who lived and worked in rural NSW, discussing issues that arise as a result of inevitable relationships with accused and others in the town.

Organizational Control Policy, Information Security Deviance, and Moderating Effect of Power Distance Orientation

Researchers generally believe that organizational control can deter employees' information security deviant behaviors. However, these relationships are not always observed. Based on the cognitive appraisal theory, this study extends the content domain of information security research by examining the moderating effect of power distance orientation, a kind of cultural value, on these relationships. In the results, first, the severity of penalty and the certainty of detection decreases employees' computer abuse. Second, employee power distance orientation moderates the relationships of the severity of penalty with employee computer abuse, such that the negative relationships are stronger for employees with higher power distance orientation. The findings suggest the deterrent function of cultural values employees hold in organizational behavior.

Imminent Capture and Noncompliance: Probing Deterrence in Extreme Environments

Understanding how deterrence operates under extreme conditions is both elusive and important. Studying suspect noncompliance in the form of flight during police-involved vehicle chases provides the opportunity to do this. These are crimes where the certainty of detection could not be higher, yet noncompliance is the end result and arguably comes because of the enhanced sanction risk rather than the obverse (deterrence) or in spite of it (defiance). Drawing from a qualitative sample of 25 auto thieves who have fled from the police, we explore their pre-chase perceptions, their motives for flight, and their decision-making processes during flight to probe the theoretical boundaries of perceptual deterrence. To this end, we pay particular attention to the mediating role of ambiguity aversion and belief updating in reconciling two seemingly inconsistent theoretical perspectives: risk framing and rational choice.

A blunted phasic autonomic response to errors indexes age-related deficits in error awareness.

Conscious error detection is impaired in older age, yet it is unclear which age-related changes in the nervous system contribute to this deficit. In younger adults, error commission is accompanied by phasic autonomic arousal, which purportedly contributes to conscious error detection. Because aging is associated with declining autonomic reactivity, reduced phasic arousal to errors may therefore contribute to age-related error detection deficits. To test this, we measured pupil dilation in younger (<30years) and older (60-80years) healthy adults during an eye movement task. The task required a subjective assessment of response accuracy, as well as a "meta-judgment" of the certainty underlying that accuracy-assessment. This allowed for a precise quantification of subjective error awareness. Behaviorally, we found reduced error awareness in older adults. Furthermore, while younger adults showed "residual" awareness of error commission on unreported errors (indicated by decreased rating certainty compared with correct responses), this effect was absent in older adults. Notably, pupil dilation correlated with both measures: between subjects, greater pupil dilation to reported errors was correlated with greater subjective certainty of error detection, and greater pupil dilation to unreported errors was correlated with greater "residual" awareness of unreported errors. In line with this association, older adults showed a reduced pupil response to both reported and unreported errors. Notably, older adults showed no pupil dilation to unreported errors, in line with their lack of "residual" error awareness on such trials. Taken together, our results suggest that reduced autonomic reactivity may contribute to age-related error awareness deficits.

No Need for Draco’s Code: Evidence from China’s “Strike Hard” Campaigns

The occasional “strike hard” campaigns against crime launched by the Chinese government provide an opportunity to isolate the separate effects of severity and certainty of punishment on the crime rate. The “strike hard” campaigns increase the severity of the punishment but keep the certainty of the punishment unchanged. We use provincial panel data from 1988 to 2015 to examine the impacts of the two strategies on the crime rate with pooled mean group models. The empirical results show that a significant decrease in crime rates is associated with greater certainty of detection, but greater severity has no significant effect. A 1% increase in the detection rate (a measurement of certainty) predicts about 2.7% lower crime rate. The results are robust even after considering the endogenous nature of punishment policies and controlling for the measurement error in the officially reported data.

A Study on the Prevention of Cyberbullying in Workplaces

The purpose of this article is to examine workplace cyberbullying as a cybercrime. Based on deterrence theory and social influence theory, this study builds a model of antecedents to prevent cyberbullying in workplaces. For this, this article conducts a survey of 305 Korean workers and uses SPSS 18.0 for hierarchical regression analysis. The results of this survey being, first, the certainty of detection prevents employees' intention to cyberbullying in the workplace while the severity of penalty and has no effect. Second, subjective norms and descriptive norms prevent employees' intention to cyberbullying in the workplace. The results show that social influence is more important to control members' behavior in workplace cyberbullying than corporate policy. And, this article is the first to investigate the preventers of employees' intentions to cyberbullying in workplace in the perspective of cybercrime.

Automatic Detection of Fasteners From Tessellated Mechanical Assembly Models

In this paper, we present multiple methods to detect fasteners (bolts, screws, and nuts) from tessellated mechanical assembly models. There is a need to detect these geometries in tessellated formats because of features that are lost during the conversions from other geometry representations to tessellation. Two geometry-based algorithms, projected thread detector (PTD) and helix detector (HD), and four machine learning classifiers, voted perceptron (VP), Naïve Bayes (NB), linear discriminant analysis, and Gaussian process (GP), are implemented to detect fasteners. These six methods are compared and contrasted to arrive at an understanding of how to best perform this detection in practice on large assemblies. Furthermore, the degree of certainty of the automatic detection is also developed and examined so that a user may be queried when the automatic detection leads to a low certainty in the classification. This certainty measure is developed with three probabilistic classifier approaches and one fuzzy logic-based method. Finally, once the fasteners are detected, the authors show how the thread angle, the number of threads, the length, and major and root diameters can be determined. All of the mentioned methods are implemented and compared in this paper. A proposed combination of methods leads to an accurate and robust approach of performing fastener detection.

Achievements and Challenges in Anti-Doping Research.

The most important element in achieving athlete compliance with anti-doping rules is the certainty of detection. Thus, scientific research plays a mission critical role in achieving clean competition. Many factors contribute to the advances in detection. Incremental advances in the ability to detect prohibited substances and methods, and identification of long-lived metabolites continue to lengthen detection windows. While the athlete biological passport hematological and steroidal modules hold great promise, experience shows that new research is needed to improve the sensitivity and specificity of the approach for current doping techniques. Indirect detection strategies using biomarkers or transcriptomic techniques have been increasingly investigated. The incorporation of more cost-effective sampling strategies using dried blood and plasma spots, oral fluid, and breath analysis show great promise toward increasing the number of tests while remaining within testing budget constraints. Despite the importance of research to ensuring rule compliance, a major challenge for anti-doping research is achieving and maintaining sufficient funding in the reality of the myriad of new substances introduced for disease treatment but abused for performance enhancement. In addition, obtaining metabolism and population reference range data, particularly for new drugs or designer drugs that have not obtained approval for administration to human subjects, remains a significant problem. Nevertheless, research continues to contribute important data to support anti-doping efforts.

Network-Wide Anomaly Event Detection and Diagnosis With perfSONAR

High-performance computing (HPC) environments supporting data-intensive applications need multidomain network performance measurements from open frameworks such as perfSONAR. Detected network-wide correlated anomaly events that impact data throughput performance need to be quickly and accurately notified along with a root-cause analysis for remediation. In this paper, we present a novel network anomaly events detection and diagnosis scheme for network-wide visibility that improves accuracy of root-cause analysis. We address analysis limitations in cases where there is absence of complete network topology information, and when measurement probes are mis-calibrated leading to erroneous diagnosis. Our proposed scheme fuses perfSONAR time-series path measurements data from multiple domains using principal component analysis (PCA) to transform data for accurate correlated and uncorrelated anomaly events detection. We quantify the certainty of such detection using a measurement data sanity checking that involves: 1) measurement data reputation analysis to qualify the measurement samples and 2) filter framework to prune potentially misleading samples. Lastly, using actual perfSONAR one-way delay measurement traces, we show our proposed scheme’s effectiveness in diagnosing the root-cause of critical network performance anomaly events.

Fragmentation of molecular ions in differential mobility spectrometry as a method for identification of chemical warfare agents

The subject of the work is the use of differential mobility spectrometry (DMS) for the detection of chemical warfare agents (CWA). Studies were performed for mustard gas, i.e., bis(2-chloroethyl)sulfide (HD), sarin, i.e., O-isopropyl methylphosphonofluoridate (GB) and methyl salicylate (MS) used as test compounds. Measurements were conducted with two ceramic DMS analyzers of different constructions allowing the generation of an electric field with an intensity of more than 120Td. Detector signals were measured for positive and negative modes of operation in a temperature range from 0 to 80°C. Fragmentations of ions containing analyte molecules were observed for all tested compounds. The effective temperatures of fragmentation estimated on the basis of dispersion plots were equal from about 148°C for GB to 178°C for MS. It was found that values of separation voltage (SV) and compensation voltage (CV) at which the fragmentation of sample ions is observed may be the parameters improving the certainty of detection for different analytes. The DMS analyzers enabling the observation of ion fragmentation can be successfully used for effective CWA detection.

Airborne LiDAR for the Detection of Archaeological Vegetation Marks Using Biomass as a Proxy

In arable landscapes, the airborne detection of archaeological features is often reliant on using the properties of the vegetation cover as a proxy for sub-surface features in the soil. Under the right conditions, the formation of vegetation marks allows archaeologists to identify and interpret archaeological features. Using airborne Laser Scanning, based on the principles of Light Detection and Ranging (LiDAR) to detect these marks is challenging, particularly given the difficulties of resolving subtle changes in a low and homogeneous crop with these sensors. In this paper, an experimental approach is adopted to explore how these marks could be detected as variations in canopy biomass using both range and full waveform LiDAR data. Although some detection was achieved using metrics of the full waveform data, it is the novel multi-temporal method of using discrete return data to detect and characterise archaeological vegetation marks that is offered for further consideration. This method was demonstrated to be applicable over a range of capture conditions, including soils deemed as difficult (i.e., clays and other heavy soils), and should increase the certainty of detection when employed in the increasingly multi-sensor approaches to heritage prospection and management.

Model-based iterative reconstruction for detection of subtle hypoattenuation in early cerebral infarction: a phantom study.

Model-based iterative reconstruction (MBIR) was recently shown to enable dose reduction in computed tomography (CT). The detectability of low-contrast lesions was assessed on CT images reconstructed with MBIR compared with the conventional filtered back-projection (FBP) method. A phantom simulating brain gray matter containing small lesions mimicking early cerebral infarctions was scanned at tube currents of 50, 100, 200, and 400 mA. Images were reconstructed by use of both methods. Round regions were cropped from the reconstructed images, half with a lesion, the other half without. Eight radiologists reviewed the images and scored the certainty of lesion detection on a 5-point scale. Overall performance was analyzed by use of a receiver operating characteristic curve. For the tube currents investigated, the analysis showed that the mean areas under the curves for the reviewers were 0.65, 0.70, 0.82, and 0.83 for FBP and 0.70, 0.76, 0.78, and 0.90 for MBIR. For each current, there was no significant difference between the areas under the curves for the different reconstruction methods (p = 0.32, 0.24, 0.49, and 0.17). For the small, low-contrast lesions in the phantom model used in this study, no significant difference between detectability was observed for MBIR and FBP.

Assessing environmental DNA detection in controlled lentic systems.

Little consideration has been given to environmental DNA (eDNA) sampling strategies for rare species. The certainty of species detection relies on understanding false positive and false negative error rates. We used artificial ponds together with logistic regression models to assess the detection of African jewelfish eDNA at varying fish densities (0, 0.32, 1.75, and 5.25 fish/m3). Our objectives were to determine the most effective water stratum for eDNA detection, estimate true and false positive eDNA detection rates, and assess the number of water samples necessary to minimize the risk of false negatives. There were 28 eDNA detections in 324, 1-L, water samples collected from four experimental ponds. The best-approximating model indicated that the per-L-sample probability of eDNA detection was 4.86 times more likely for every 2.53 fish/m3 (1 SD) increase in fish density and 1.67 times less likely for every 1.02 C (1 SD) increase in water temperature. The best section of the water column to detect eDNA was the surface and to a lesser extent the bottom. Although no false positives were detected, the estimated likely number of false positives in samples from ponds that contained fish averaged 3.62. At high densities of African jewelfish, 3–5 L of water provided a >95% probability for the presence/absence of its eDNA. Conversely, at moderate and low densities, the number of water samples necessary to achieve a >95% probability of eDNA detection approximated 42–73 and >100 L, respectively. Potential biases associated with incomplete detection of eDNA could be alleviated via formal estimation of eDNA detection probabilities under an occupancy modeling framework; alternatively, the filtration of hundreds of liters of water may be required to achieve a high (e.g., 95%) level of certainty that African jewelfish eDNA will be detected at low densities (i.e., <0.32 fish/m3 or 1.75 g/m3).