Celiac Ganglionectomy Research Articles

Results of Surgical Treatment of Chronic Pancreatitis Report of 142 Cases

The authors report on 142 patients treated surgically for chronic pancreatitis. They had an average age of 43.5; 34.5% were calcific; 62.7% were alcoholics: 28.9% had cysts; 19% had diabetes; 16.9% had steatorrhea; and all had pain. A follow-up of 55 patients undergoing pancreaticojejunostomy showed that, 4--21 years following operation 16 had marked improvement, 11 had some relief, four were not relieved from pain, and 24 had died, three within one month postoperatively and 21 later. Eighty to ninety-five per cent pancreatectomy was more effective in relieving pain in the 9 patients subjected to this type of resection than was the 50--80% pancreatic resection used in 16 patients. Pancreaticoduodenectomy was of some value in three of five patients so operated. Celiac ganglionectomy, used in 22 patients, and sphincteroplasty, used in 35 patients, were less effective in relieving symptoms than the other procedures.

Course of posthemorrhagic hypotension after celiac ganglionectomy with and without adrenal denervation.

Course of posthemorrhagic hypotension after celiac ganglionectomy with and without adrenal denervation.

Treatment of pancreatitis by left splanchnicectomy and celiac ganglionectomy: Analysis of 146 cases

Splanchnicectomy is an effective treatment for recurrent pancreatitis when used for patients without stones in the pancreas or bile duct and without dilated pancreatic duct.

Depletion of splenic norepinephrine in rat by celiac ganglionectomy.

Excision of the celiac ganglion of the rat results in total depletion of splenic norepinephrine, indicating the necessity of an intact sympathetic innervation for maintenance of normal levels of catecholamines in the spleen of this species.

Total thoracic and partial to total lumbar sympathectomy, splanchnicectomy and celiac ganglionectomy for hypertension.

Total thoracic and partial to total lumbar sympathectomy, splanchnicectomy and celiac ganglionectomy for hypertension.

Effects of vagotomy, splanchnicectomy and celiac ganglionectomy on experimentally produced spasm of sphincter of Oddi in animals.

Effects of vagotomy, splanchnicectomy and celiac ganglionectomy on experimentally produced spasm of sphincter of Oddi in animals.

Effect of Celiac Ganglionectomy and Thoracolumbar Sympathectomy or Adrenal Medullectomy on Histamine Ulcer in Dogs

ConclusionThe potentiating effect of postganglionic sympathectomy, by a celiac ganglionectomy, on histamine induced ulcer in dogs is abolished by a bilateral thoracolumbar sympathectomy or adrenal medullectomy.

RESULTS OF HIGH DORSOLUMBAR SYMPATHECTOMY FOR HYPERTENSION

Article1 February 1949RESULTS OF HIGH DORSOLUMBAR SYMPATHECTOMY FOR HYPERTENSIONJAMES A. EVANS, M.D., F.A.C.P., CARL C. BARTELS, M.D.JAMES A. EVANS, M.D., F.A.C.P.Search for more papers by this author, CARL C. BARTELS, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-30-2-307 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptIt has been the custom at the Lahey Clinic for the medical department to choose and recommend certain hypertensive patients for dorsolumbar sympathectomy as well as to follow their postoperative and subsequent course. This report is an attempt on our part to evaluate the results of operation in a strictly critical and unbiased manner based upon a six month to three year follow-up on 173 patients who had sympathectomies to include the fourth thoracic level.Our first series of 54 cases in which resection was carried out to the eleventh or twelfth thoracic level, reviewed by E. C. Bartels1in...Bibliography1. BARTELSPOPPENRICHARDS ECJLRL: Surgical treatment of hypertension (results in 52 cases), Ann. Int. Md., 1942, xvii, 807-811. Google Scholar2. POPPENLEMMON JLC: The surgical treatment of essential hypertension, Jr. Am. Med. Assoc., 1947, cxxxiv, 1-9. Google Scholar3. FREISSMITHWICK EDRH: The effect of lumbodorsal splanchnicectomy on the blood volume and thiocyanate space of patients with essential hypertension, Am. Jr. Med. Sci., 1947, ccxiv, 363-367. CrossrefGoogle Scholar4. PALMER RS: Medical evaluation of the surgical treatment of hypertension, Jr. Am. Med. Assoc., 1947, cxxxiv, 9-14. CrossrefGoogle Scholar5. SMITHWICK RH: The surgical treatment of continued hypertension; some suggestions about selection of cases for this form of therapy, Jr. Med. Soc. New Jersey, 1947, xliv, 304-316. Google Scholar6. DE TAKATS G: Technique for splanchnic resection for hypertension; preliminary report, Surgery, 1940, vii, 1-8. DE TAKATS, G., GRAUPNER, G. W., FOWLER, E. F., and JENSIK, R. J.: Surgical approach to hypertension. Second report, Arch. Surg., 1946, liii, 111-163. Google Scholar7. GRIMSON KS: Total thoracic and partial to total lumbar sympathectomy and celiac ganglionectomy in treatment of hypertension, Ann. Surg., 1941, cxiv, 753-755. CrossrefGoogle Scholar8. KEITHWAGENERBARKER NMHPNW: Some different types of essential hypertension; their course and prognosis, Am. Jr. Med. Sci., 1939, cxcvii, 332-343. CrossrefGoogle Scholar9. BRIDGESJOHNSONSMITHWICKWHITE WCALRHPD: Electrocardiography in hypertension (study of patients subjected to lumbodorsal sympathectomy), Jr. Am. Med. Assoc., 1946, cxxxi, 1476-1480. CrossrefGoogle Scholar10. DE TAKATSFOWLERJORDANRISLEY GEFPTC: Sympathectomy in the treatment of peripheral vascular sclerosis, Jr. Am. Med. Assoc., 1946, cxxxi, 495-499. DE TAKATS, G., and EVOY, M. H.: Sympathectomy for peripheral vascular sclerosis, Jr. Am. Med. Assoc., 1947, cxxxiii, 441-445. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: *Read at the Twenty-Ninth Annual Session of the American College of Physicians, San Francisco, California, April 23, 1948.From the Lahey Clinic. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byHuman hypertension, sympathetic activity and the selfish brainHypertonieHypertonieShould Sympathectomy for Arterial Hypertension Be Abandoned?: Review of Surgical Therapy at the Lahey Clinic: 1950-1954Results of Splanchnicectomy on Patients with Hemorrhagic Hypertensive RetinitisTwenty Years' Experience with the Surgery of HypertensionSurgical Treatment of HypertensionTreatment of essential hypertension with β-alkylamines, especially dibenzylineSYMPATHECTOMY IN THE TREATMENT OF HYPERTENSION REVIEW OF 122 CASESSympathektomieBlutdruck und vegetatives NervensystemDie HochdruckkrankheitDas RegenerationsproblemThe Effects of Splanchnicectomy on the Blood Pressure in HypertensionSplanchnicectomy: Its Clinical Effects on the Gastrointestinal TractPathogenesis of hypertensionHypertensionSelection of Patients for Sympathectomy 1 February 1949Volume 30, Issue 2Page: 307-329KeywordsHypertensionSympathectomy ePublished: 1 December 2008 Issue Published: 1 February 1949 PDF downloadLoading ...

Effect of Celiac Ganglionectomy upon Experimental Peptic Ulcer Formation.

Conclusions1. Postganglionic sympathectomy of the gastrointestinal tract potentiates the susceptibility to the histamine-induced ulcer in dogs. 2. This increased susceptibility to ulcer formation has continued over the longest interval during which a dog was observed, in one instance for 499 days following celiac ganglionectomy.

Observations on abdominal visceral pain pathways in patients undergoing celiac ganglionectomy and vagotomy or sympathectomy

Observations on abdominal visceral pain pathways in patients undergoing celiac ganglionectomy and vagotomy or sympathectomy

HYPERTENSION

Restriction of activity, extension of periods of rest and natural sleep, and generous use of sedatives are commonly employed in the medical treatment of Splanchnicectomy (Peet,1Craig and Adson,2Smithwick3and others) or subtotal to total paravertebral sympathectomy, splanchnicectomy and celiac ganglionectomy (Grimson4) have been of value as occasional supplements to medical management. Selection of patients for surgery has proved difficult. The effect of rest and sodium amytal on hypertension determined by hourly blood pressure readings during twenty-four hours or more has been emphasized by many physicians as one of several important factors indicating the advisability of surgery. Vasomotor instability evidenced by abnormal elevations of blood pressure during reflex or emotional stimulation has long been recognized in many patients and associated with the term neurogenic hypertension. The function of the sympathetic nervous system in mediating such elevations of blood pressure and the important role of

Effective renal blood flow, glomerular filtration rate and tubular excretory mass in arterial hypertension. II. Effect of supradiaphragmatic splanchnicectomy with lower dorsal sympathetic ganglionectomy: Foà, P. P., Woods, W. W., Peet, M. M., and Foà, N. L.: Arch. Int. Med. 71: 357, 1943

Chronic and primary recurrent pancreatitis can be divided into two categories: (1) pancreatitis associated with a lesion or an obstruction of the duct of Wirsung or a perforation of the duct due to necrosis, indicating direct surgical intervention, and (2) primary parenchymal pancreatitis without dilatation of the duct of Wirsung for which pancreatectomy has no place. Numerous arguments have been advanced for the correct operative procedures in the sympathetic system: splanchnicectomy, left celiac ganglionectomy, and postganglion neurectomy. The consistent success of these operations, when their indications are correct, is the best argument for their use.The operation is always carried out in two steps: First, exploratory laparotomy is performed to define the pancreatic lesion and the condition of the duct of Wirsung and biliary tract. Second, sympathetic resection by subperitoneal and subpleural lumbar approach is carried out.The mortality in 215 patients who underwent splanchnicectomy and left celiac ganglionectomy operations was 4.7 percent. In 127 patients followed for 5 years, there were 14 unsatisfactory results including 3 late recurrences, 5 improvements, and 108 definite cures (50 for 20 years, 8 for between 20 and 34 years); that is, there were no relapses of painful attacks, and there was general improvement and weight gain. These results were also observed in alcoholics, but in such patients recovery may be interrupted by the development of hepatic cirrhosis. Splanchnicectomy or left celiac ganglionectomy is not a symptomatic operation for analgesia but rather a curative one, and the cure rate is remarkably stable. This is contrary to the degeneration so frequently observed after pancreatectomy.

STUDIES ON THE MECHANISM OF VOMITING PRODUCED BY STAPHYLOCOCCUS ENTEROTOXIN

THE EMETIC ACTION OF STAPHYLOCOCCUS ENTEROTOXIN WAS TESTED ON YOUNG AND ADULT CATS UNDER VARIOUS EXPERIMENTAL CONDITIONS WITH THE FOLLOWING RESULTS: 1. No direct action on isolated intestinal strips was observed. 2. Emesis resulted following intravenous, intracardial, and intraperitoneal injections, but failed to appear subsequent to oral, subcutaneous, or intramuscular administration. 3. Emesis occurred following (a) celiac ganglionectomy, (b) gastrectomy, (c) spinal cord transection at T(2) or caudad, and (d) unilateral vagotomy. 4. Mild retching movements and rarely emesis resulted subsequent to enterotoxin injection following (a) double vagotomy, (b) abdominal evisceration, and (c) spinal cord transection at C(7). 5. Emesis never occurred following (a) destruction of the vomiting center, (b) injection of enterotoxin into the fourth ventricle over the vomiting center, and (c) transection of the central nervous system between the anterior border of the pons and the posterior border of the hypothalamus. 6. Morphine inhibited, ergotoxine inhibited or delayed, while atropine and pentobarbital had little or no effect on emesis due to enterotoxin injection. These experiments indicate that the action of staphylococcus enterotoxin on peripheral sensory structures is of greater importance in the initiation of emesis than direct action of the enterotoxin on the vomiting center. The principal pathways of the afferent and efferent impulses are described.

Celiac Ganglionectomy for Raynaud's Disease: Further Report of a Case Operated on Three Years Ago

Celiac Ganglionectomy for Raynaud's Disease: Further Report of a Case Operated on Three Years Ago

Decapsulation of the Kidney in the Course of Celiac Ganglionectomy for Essential Hypertension

Decapsulation of the Kidney in the Course of Celiac Ganglionectomy for Essential Hypertension

Two Year Results of the Treatment of Essential Hypertension by Celiac Ganglionectomy

Two Year Results of the Treatment of Essential Hypertension by Celiac Ganglionectomy

The Results of Celiac Ganglionectomy in Cases of Essential Hypertension

The Results of Celiac Ganglionectomy in Cases of Essential Hypertension

A Note of the Effect of Coeliac Ganglionectomy on the Sensibility Against Insulin and Adrenaline

It has been affirmed that removal of the coeliac ganglia acts also in rabbits to increase the sensibility against insulin, and to decrease that against adrenaline in regard to their glycaemia action, but the effects do not continue long, rather definitely shorter than the doubly splanchnicotomy, the double suprarenalectomy, in respect to the insu-lin matter.

Influence of Vagi and Splanchnics upon Blood Sugar Response to Glucose Administration.

1. Section of the vagus nerves below the diaphragm was found to have no effect on the tolerance of normal dogs to intravenously injected glucose. No evidence was obtained which pointed to secretory or tonbc inhibitory fibers in either of the vagus nerves. 2. Removal of one adrenal and denervation of the other resulted in a slightly more rapid fall in blood sugar after intravenous injection of glucose. This difference in rate, though persistent in the animal studied, was nevertheless small and of doubtful significance. 3. Celiac ganglionectomy after bilateral vagus section and after removal of one adrenal and denervation of the other was without effect on glucose tolerance. 4. No evidence was obtained in normal dogs to substantiate a theoretical basis for op erative procedures designed to increase tolerance to glucose.

Effect of Celiac Ganglionectomy on Sugar Tolerance of Dogs

Effect of Celiac Ganglionectomy on Sugar Tolerance of Dogs