Caudal Nerve Conduction Velocity Research Articles

Nervous system function: Behavioral influences of gene effects on peripheral nerve conduction velocity in mice

Strains of mice different with regard to caudal nerve conduction velocity are shown to differ in reflex behavior which involves sciatic nerve function. The pattern of behavioral differences is exactly that which would be predicted if gene differences effecting caudal nerve had simultaneous effects on sciatic velocity. About 12% of the phenotypic variance in this behavior is due to additive genetic variance.

Physiological function and behavioral genetics. II. Quantitative genetic an analysis of conduction velocity of caudal nerves of the mouse, Mus musculus.

Scores for body weight, tail length, and caudal nerve conduction velocity (assessed by direct, in vivo methods) from 1701 mice from the DBA/1J and C3H/HeJ inbred strains and their derived generations were employed for genetic analysis. Substantial strain differences were observed for the three characters, and hybrid scores exceeded those of inbreds. Within the reciprocal backcrosses, mating groups with inbred female parents had lower average scores for the three variables than did groups with hybrid female parents. The nature of this maternal influence is being examined. Heritability estimates from comparison of generation variances were high and not consistent. Those from generation means were lower, consistent, and in close agreement with estimates from regression of F3 offspring on their F2 parent scores. The heritability of conduction velocity in this population is apparently about 0.10. Regression estimates of heritability using 950 animals from an eight-way cross suggest that the heritability of caudal nerve conduction velocity in that population is about 0.20. From both populations, a slight positive genetic correlation among the characters is indicated.

Changes in rat ventral caudal nerve conduction velocity during cold exposure.

ARTICLESChanges in rat ventral caudal nerve conduction velocity during cold exposureJH PetajanJH PetajanPublished Online:01 Jan 1968https://doi.org/10.1152/ajplegacy.1968.214.1.130MoreSectionsPDF (578 KB)Download PDF ToolsExport citationAdd to favoritesGet permissionsTrack citations ShareShare onFacebookTwitterLinkedInEmailWeChat Previous Back to Top Next Download PDF FiguresReferencesRelatedInformationCited ByCholinesterase inhibition and depression of the photic after discharge of flash evoked potentials following acute or repeated exposures to a mixture of carbaryl and propoxurNeuroToxicology, Vol. 33, No. 3Neurotoxicity of carbonyl sulfide in F344 rats following inhalation exposure for up to 12 weeksToxicology and Applied Pharmacology, Vol. 200, No. 2Encoding of tensile stress and strain during stretch by muscle mechano-nociceptors1 January 2004 | Muscle & Nerve, Vol. 30, No. 2Encoding of Compressive Stress During Indentation by Group III and IV Muscle Mechano-Nociceptors in Rat Gracilis MuscleWeiqing Ge, and Partap S. Khalsa1 February 2003 | Journal of Neurophysiology, Vol. 89, No. 2Flash-, somatosensory-, and peripheral nerve-evoked potentials in rats perinatally exposed to Aroclor 1254Neurotoxicology and Teratology, Vol. 23, No. 6Responses of Rapidly Adapting Afferent Neurons to Dynamic Stretch of Rat Hairy SkinZaccaria Del Prete, and Peter Grigg1 August 1998 | Journal of Neurophysiology, Vol. 80, No. 2Heat-producing organ of the swordfish (Xiphias gladius): A modified eye muscleJournal of Morphology, Vol. 234, No. 1Tensile and Compressive Responses of Nociceptors in Rat Hairy SkinPartap S. Khalsa, Robert H. Lamotte, and Peter Grigg1 July 1997 | Journal of Neurophysiology, Vol. 78, No. 1Nerve conduction velocity decrease and synaptic transmission alterations in caffeine-treated ratsNeurotoxicology and Teratology, Vol. 16, No. 1Prevention of the acute neurotoxic effects of phenytoin on rat peripheral nerve by H7, an inhibitor of protein kinase CToxicology, Vol. 75, No. 3Temperature dependence of the toxic effects of phenytoin on peripheral neuromuscular function of the rat tailNeurotoxicology and Teratology, Vol. 12, No. 6Hypothermia-induced reversible polyneuropathy: Electrophysiologic evidence of axonopathyPediatric Neurology, Vol. 4, No. 1Acute effects of phenytoin on peripheral nerve function in the ratMuscle & Nerve, Vol. 4, No. 1Thermal relations of nervous conduction in the tortoiseComparative Biochemistry and Physiology Part A: Physiology, Vol. 60, No. 1TEMPERATURE ACCLIMATION AND THE NERVOUS SYSTEMBiological Reviews, Vol. 49, No. 4The Effects of Cold Exposure and Exercise Upon Peripheral FunctionArchives of Environmental Health: An International Journal, Vol. 24, No. 5RODENTS More from this issue > Volume 214Issue 1January 1968Pages 130-132 Copyright & PermissionsCopyright © 1968 by American Physiological Societyhttps://doi.org/10.1152/ajplegacy.1968.214.1.130PubMed5634515History Published online 1 January 1968 Published in print 1 January 1968 Metrics