Cases Of Vaginitis Research Articles

Shigella Vaginitis

Thirty-eight cases of Shigella vaginitis were identified in a retrospective review of records kept over the past 14 years. The cases of vaginitis were due to three subgroups of Shigella. Vaginitis varied in severity and duration, persisting for several months in some instances. In 47% of the cases, there was associated bloody vaginal discharge. Only two children had diarrhea temporally associated with vaginitis, but six others had had diarrhea. Many treatment modalities were used. Systemic antibiotic therapy appeared more effective than topical antimicrobials in the few patients who could be evaluated. Review of the literature revealed 32 additional cases, including four in adult women.

Shigella Vaginitis: Report of 38 Patients and Review of the Literature

Thirty-eight cases of Shigella vaginitis were identified in a retrospective review of records kept over the past 14 years. The cases of vaginitis were due to three subgroups of Shigella. Vaginitis varied in severity and duration, persisting for several months in some instances. In 47% of the cases, there was associated bloody vaginal discharge. Only two children had diarrhea temporally associated with vaginitis, but six others had had diarrhea. Many treatment modalities were used. Systemic antibiotic therapy appeared more effective than topical antimicrobials in the few patients who could be evaluated. Review of the literature revealed 32 additional cases, including four in adult women.

Abnormal forms of Trichomonas vaginalis.

Abnormal forms of Trichomonas vaginalis have been demonstrated by both conventional and scanning electron microscopy after inoculation of media with clinical material from cases of trichomonal vaginitis. Twenty-six cases of vaginitis have been studied; 10 of them showed the abnormal forms of trichomonads after growth in a modification of the medium described by Bushby and Copp (1955), while 16 showed only normal forms.

Cases of vaginitis treated with Polmiror.

Cases of vaginitis treated with Polmiror.

Taxonomy of Haemophilus vaginalis

THE numerous authors who have reported the isolation of ‘Haemophilus vaginalis’ from cases of vaginitis, or of non-specific urethritis in men, have not succeeded in determining its X and V requirements; thus its taxonomic position is uncertain. We have therefore examined six strains of H. vaginalis—two from C. D. Dukes, who with Gardner first described this species1, and four from P. N. Edmunds2.

Experiences in a Vaginitis Clinic

To the Editor:— The article by Dr. W. R. Lang on Experiences in a Vaginitis Clinic inThe Journalof Dec. 3, 1960, p. 1814, makes no mention of Neisseria gonorrheae as the causative organism in any of the many hundreds of cases of vaginitis in adults. Unless gonorrhea cases were excluded from the series without mention in the article, it is indeed most unusual if N. gonorrheae were not identified by appropriate cultural methods in any of these cases.

Cervicitis clinic—Twenty-five years in review

In 1930 the late Dr. Otto Schwarz organized a cervicitis clinic for the referral of patients who needed a special study for classification of their benign cervical lesions. We undertook the study of cervicitis as to its etiology, occurrence, prognosis, and therapy. These studies were made available to the residents, assistant residents, nurses, and visiting doctors who were taking refresher courses in gynecology.The personnel of the general Out-Patient Gynecological Clinic selected patients who had cervical lesions exclusive of acute gonorrhea and proved cervical cancer. These patients were to be treated by other specialized subclinics. It was the policy of the cervicitis clinic to avoid becoming involved with cases of vaginitis unless such cases were secondary to chronic cervical infection. A large number of such patients were referred to the cervicitis clinic, however. In the majority of such cases, there was marked improvement in the vaginitis when the cervicitis was adequately treated. Patients who had a primary vaginitis were sent back to the general gynecological clinic with recommendation for some specific therapy.

Comparative bacteriology of vaginal trichomonad infestations: A study of 190 clinical cases

Microorganisms in the human vaginal vault were isolated from 104 clinical cases of Trichomonas vaginalis vaginitis and are compared and contrasted with the microflora isolated from a control series of 86 normal patients without vaginal discharge or any clinically confirmable manifestations of a trichomonad infestation. The bacteria isolated in both series are strikingly similar in distribution both as to species and frequency of presence.No single bacterial or fungus organism is associated with the flagellate, Trichomonas vaginalis, in clinical cases of vaginitis that does not appear in the normal vagina. Döderlein bacilli or diphtheroid rods appear to be present in a similar frequency in the trichomonad-infested vagina and the normal vagina. Common to all cases of trichomonad vaginitis in this series is the flagellate, Trichomonas vaginalis. These data would appear to support the contention that this trichomonad is the etiological agent in a specific vaginitis.

GONOCOCCIC VAGINITIS IN CHILDREN TREATED WITH A SINGLE INJECTION OF PENICILLIN IN BEESWAX AND PEANUT OIL

PENICILLIN given as a single injection in the beeswax and peanut oil mixture developed by Romansky¹has been reported²to be from 80 to 100 per cent effective in the treatment of gonorrhea in adults. The present study was undertaken because to our knowledge the effectiveness of this method of administration of penicillin in a group of cases of vaginitis in children has not been reported. <h3>MATERIAL</h3> The patients were 20 Negro girls, ranging from 2 to 10 years of age, with uncomplicated, previously untreated gonococcic vaginitis (table). They were treated by the staff of the Chicago Municipal Social Hygiene Clinic between April 1945 and June 1946. Purulent or mucopurulent vulvovaginal exudate was present in each patient with local inflammatory signs of varying degree, often mild. At least one smear of the vaginal secretion showed typical gram-negative intracellular diplococci before treatment, which was not withheld pending report of

TREATMENT OF GONOCOCCIC INFECTIONS IN CHILDREN WITH SULFANILAMIDE

On the suggestion that the gonococcus was one of the organisms susceptible to sulfanilamide, it was decided to treat gonorrheal vaginitis in children by oral administration of sulfanilamide in further search for a simple and effective method of handling this therapeutic problem. After encouraging results had been obtained in cases of vaginitis, sulfanilamide was applied to the treatment of gonorrheal urethritis in boys and of gonorrheal conjunctivitis. This report summarizes the results of treatment with sulfanilamide in 9 cases of conjunctivitis, in 5 cases of urethritis in boys and in 22 cases of vaginitis in girls since May 1937. Diagnosis of gonococcic infection was made on the basis of the finding of gram-negative intracellular diplococci, morphologically typical of gonococci, in smears from the eyes, urethra or vagina. Gonococcic complement fixation tests made on admission were positive in about two thirds of the patients. Cultures for gonococci were not available to

Experimental Gonococcal Infection in the Chick Embryo

It has been found that gonococci remain viable within the interior of a hen's egg for several weeks and in certain cases as long as 3 months. Table 1 illustrates the frequency with which the organism was recovered from eggs at varying periods of time after inoculation.Serial inoculations made from egg to egg showed that the organism also multiplied within the interior of the yolk.Inasmuch as the embryo develops at a temperature of 37° C (and in certain instances hatches) and since the gonococcus seemed to multiply at this temperature within the egg, it appeared possible that during development the blood stream might be invaded by the organism if introduced into the yolk-sac.Accordingly fertile eggs were incubated at 37°C and when the embryo had grown to the 12-23-day stage the yolk-sac was inoculated as follows:A strain from a case of vaginitis in a young girl was grown on Bradford's medium and after 48 hours was washed off with one cc. of saline. A small area, one cm. in diameter, on the shell was steril...

Plaut-Vincent's infection of the vagina: A case report

1.1. A case of vaginitis due to infection with the fusiform bacillus and spirilli organisms is reported.2.2. It is of some interest that in the majority of the cases reported, other parts of the body, usually the mouth, were also infected with the Plaut-Vincent's organisms.

VULVOVAGINITIS IN CHILDREN

For two years and a half, under the direction of Dr. William P. Lucas, the cases of vaginitis at the Children's Hospital in Boston have been treated at a special clinic. During the two years the individual cases have been studied and the attempt has been made to gain some progress in the treatment and knowledge of this very intractable disease. The purpose of this article is to emphasize the following five things, which stand out clearly as the result of our experience and the experience of others: 1. The prevalence of the gonococcus as the etiologic factor in cases of vaginitis, and the unreliability of bacteriologic examination in all stages. 2. The total duration of the disease, including the long periods of latency. 3. The importance of the disease on account of its serious complications and sequelae. 4. Inefficiency of treatment at best. 5. The consequent importance of prophylaxis,