Chitosan-assisted cinnamaldehyde utilization and sodium carboxymethyl cellulose-enabled redispersion: A dual strategy for pathogen-specific grape preservation.

Development of active food packaging using carboxymethyl cellulose/gelatin composites reinforced with carbon quantum dots derived from pumpkin peel waste.

Physical and biological synergistic strategies: injectable CNF/CMC hydrogels with cannabidiol@PCL microspheres for durable facial filling.

Constructing a 3D printed composite gel using sodium carboxymethylcellulose and gelatin

High-performance conductive eutectogel synthesized by carboxymethyl cellulose-enhanced physicochemical dual network for supercapacitors and wearable electronic devices.

Ultralight, superelastic and nitrogen-doped graphene/dopamine-grafted carboxymethyl cellulose composite aerogels with negligible shrinkage for oil/heavy-metal capture

Retraction notice to "Drug delivery based on chitosan, β-cyclodextrin and sodium carboxymethyl cellulose as well as nanocarriers for advanced leukemia treatment" [Biomedicine & Pharmacotherapy 153 (2022) 113369

Light-responsive anthocyanin-Fe(III) self-assembled nanoparticles for improving the performance of cellulose films and preservation of cooked meat.

Allergic rhinitis (AR) is a prevalent inflammatory condition with complex pathophysiology and limited treatment options. Given the current lack of drugs with significant therapeutic effects, it is necessary to develop a hydrogel that can effectively control the nasal inflammation in AR. An injectable and self-healing disulfide bond hydrogel was prepared by cross-linking L-selenocysteine (L-CySe) with carboxymethyl cellulose (CMC). The microstructure, porosity, swelling property, degradability, rheology and mechanical properties of the L-CySe/CMC (SeC) hydrogel were characterized. The antioxidant and antimicrobial activities were evaluated in vitro. The air-liquid interface (ALI) of human nasal epithelial cells stimulated by IL-4. The murine AR model was created by using ovalbumin (OVA). The histopathology of mice and ALI model was analyzed by hematoxylin and eosin (H&E) staining, PAS and Sirius red staining for eosinophils. The levels of OVA-specific IgE (OVA-sIgE) and type 2 cytokines were detected by using ELISA. The biosafety of SeC hydrogel was confirmed by hemolysis, Cell Counting 8 Kit (CCK-8 kit), Live/Dead staining and histopathological examination. SeC hydrogel features a uniform porous structure (porosity of 60.26%), an appropriate swelling/degradation curve, excellent mechanical strength (compressive modulus of 24.74 kPa), and rapid self-healing ability. In both models, it demonstrated a powerful free radical scavenging capacity (>66%), broad-spectrum antibacterial activity (>97% inhibition), and significant anti-inflammatory effects. Hydrogels have good blood compatibility (hemolysis rate <5%) and no cell and organ toxicity. In ALI stimulated by IL-4, it reduced epithelial thickness and inhibits goblet cell proliferation. In AR mice, it alleviated nasal symptoms, reduced epithelial thickening, eosinophil infiltration, goblet cell proliferation, and decreased the levels of OVA-sIgE and type 2 cytokines (IL-4, IL-5, IL-13). SeC hydrogel provides an effective and promising treatment strategy for the effective treatment of allergic rhinitis by taking advantage of its synergistic antioxidant, antibacterial and anti-inflammatory properties.

Enhanced the leaching of copper oxide ores with carbonate-rich gangue using carboxymethyl cellulose as an interfacial reaction inhibitor

Multi-level design of a chitosan-based membrane: from sisal fiber reinforcement to surface micropatterning and hybrid hap for enhanced bone regeneration.

Intelligent bilayer films based on polyvinyl alcohol/carboxymethyl cellulose-chitosan for efficient preservation and real-time freshness indication of beef.

Keratin was extracted from human hair waste and incorporated with neem-mediated silver nanoparticles (AgNPs), carboxymethyl cellulose, and aloe vera to fabricate a transparent nanocomposite film. The extracted keratin exhibited a characteristic protein peak and porous morphology, while AgNPs demonstrated a surface plasmon resonance at 430-460nm with spherical shape (< 100nm). The fabricated film demonstrated high transparency (75.67 ± 0.57%), moderate porosity (63.38 ± 0.61%), and a high swelling ratio (818.36%), supporting moisture retention; its surface pH (5-6) and water vapor transmission rate (1799 ± 43g/m²/day) favouring a moist healing environment, with 36.23% biodegradation over 28 days. The film showed potent bactericidal and antibiofilm properties towards S. pyogenes, E. coli, S. aureus, and P. aeruginosa, antioxidant activity (TPC 24.22mg GAE/g, DPPH 71.31%, ABTS 63.55%), and anti-inflammatory effects (BSA 68.69%, egg albumin 92.91%, RBC 66.69%). Cytocompatibility on HaCaT and L929 cells (IC₅₀ = 155 and 251µg/mL) confirmed the film's safety and regenerative potential. Overall, the fabricated biodegradable, bioactive, and cytocompatible composite film provides a multifunctional platform for wound healing by preserving moisture, reducing inflammation and infection, and promoting the regeneration of tissue. Future studies focusing on in vivo validation and long-term biocompatibility are important to confirm the film's scalability, sustainability, and clinical applicability.

Enhanced heat transfer of carboxymethyl cellulose coupled nanofluids in eccentric static mixers integrated CFD-GA-MLP approach

Development of biosafe MOF-based highly sensitive carboxymethyl cellulose interpenetrating gelatin network smart freshness aerogel tags for real-time graded shrimp freshness monitoring.

The electrochemical chiral sensing platform constructed with a single chiral selector relies on static interactions to identify enantiomers, lacks signal amplification, and has limited sensitivity. Therefore, it is usually combined with a conductive substrate, and active sites are introduced to accelerate electron transfer, thereby amplifying the chiral recognition signal. Catalytically active sites typically require a highly unsaturated, high-energy state (e.g., single atoms), yet such sites readily agglomerate or become poisoned under the reaction conditions. Thus, beyond conductivity and loading stability, the stability of active sites and tolerance to acidic and basic environments are more critical. Compared with single atoms and large nanoparticles, nanoclusters maintain high activity while exhibiting superior long-term stability under harsh conditions, making them a key strategy for an efficient catalyst design. Herein, we introduce Ir nanoclusters into the 5,10,15,20-tetra(4-pyridyl)-21H,23H-porphine (Tpyp) substrate to create catalytically active sites and anchor them through the coordination of Ir and N atoms to enhance the catalytic stability. In addition, Ir was oxidized to IrO2 to optimize the electronic structure of the catalytic sites of the clusters, resulting in more abundant synergistic active sites and improving the chemical stability of Ir nanoclusters under adverse conditions. Then, using modified sodium carboxymethyl cellulose as a chiral source, an electrochemical chiral sensing platform with high loading capacity and high catalytic activity was constructed.

ABSTRACT The presence of oil in water can have a devastating impact on the environment, harming wildlife, ecosystems, and water quality. The oil content in industrial wastewater typically varies from 100 to 1000 mg/L, necessitating a reduction to 5 mg/L before discharge. To address the treatment of these oil-water emulsions, tubular membranes were produced using a horizontal extrusion method. The membranes comprised fly ash, quartz, calcium carbonate, and α-alumina in a weight ratio of 70%, 20%, 5%, and 5%, respectively. A solution of 2 wt.% carboxymethylcellulose (CMC) sodium salt in water is used as a binder for the ceramic precursors. The sintered membranes at 1100°C (FA_1100) and 1200°C (FA_1200) were found to have average pore diameters of 0.15 and 0.11 μm, porosity of 37.31 and 36.67%, and mechanical stability of 31.65 and 38.53 MPa, respectively. The pure water permeability of FA_1100 and FA_1200 was estimated to be 9.89 × 10−8 and 3.79 × 10−8 m3 /m2.kPa.s, respectively. The separation efficiency of these membranes was evaluated through cross-flow filtration at five different pressure levels, ranging from 69 kPa to 345 kPa for an oil-water emulsion of concentration 100 mg/L. The oil removal efficiency of the membranes increased progressively with increasing pressure, and complete oil removal was observed at a pressure of 345 kPa. The membrane FA_1100 showed the best permeate flux and rejection combination. The permeate produced from these ceramic membranes is fully reusable in the oil industry, which can contribute to addressing the current water scarcity issue. Research highlights A cost-effective tubular ceramic membrane for treating oil-water emulsions has been developed domestically. Increasing the sintering temperature reduces the porosity and pore size of the prepared membrane. Membranes displayed superior compressive strength compared to other clay-based membranes. Complete removal of oil was achieved using the membrane under crossflow mode.

This study investigates the thermal and flow characteristics of fully developed turbulent non-Newtonian (power-law type) nano and hybrid nanofluids flowing through a horizontal pipe under constant heat flux. Carboxymethylcellulose (CMC) solution is used as the base fluid, while Al₂O₃, CuO and hybrid (Al₂O₃+CuO) nanoparticles are employed as additives. The governing equations are non-dimensionalized and solved under steady-state and axisymmetric assumptions. Nusselt number, friction factor, and thermal performance ratio (TPR) are analyzed. Results show that hybrid nanofluids provide approximately %15–20 higher heat transfer enhancement compared to mono nanofluids, while the increase in friction factor remains moderate. The optimum particle volume fraction is found to be around φ≈%2.5. This study demonstrates that hybrid nanofluids in non-Newtonian matrices are efficient alternatives for improving convective heat transfer in turbulent flow systems.

Due to their poor resistance to swelling, developing biomass-based radionuclide-capturing aerogel adsorbents with high adsorption capacity and excellent mechanical stability remains a significant challenge. This paper describes a dual-network aerogel constructed using a multiscale interface-control strategy, leveraging Zn2+-induced chitosan precross-linking and entanglement of oxidized carboxymethyl cellulose (ox-CMC). Within this stable framework, ZIF-8 nanoparticles were synthesized in situ. This design, through physical entanglement and chemical cross-linking, suppressed the swelling of the dual-network framework. After 30 days of soaking, its tensile strength remained approximately 0.48 MPa, and it also exhibited good compressive resilience. Simultaneously, the nitrogen-rich channels of ZIF-8 synergize with the negatively charged surface of the dual network (zeta potential: -40.5 mV), resulting in an Sr2+ adsorption capacity of 226.8 mg/g, which is significantly higher than that of many clay- or polymer-based adsorbents. After 10 adsorption-desorption cycles, the aerogel retained 85.8% of its initial properties. This multiscale interface design provides a robust strategy for preparing swelling-resistant, high-performance biomass aerogels for advanced radioactive wastewater treatment.

Buccal administration of peptide therapeutics offers a noninvasive alternative to injections but remains constrained by limited peptide epithelial permeability and physicochemical instability. Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) are important therapeutics with limited noninvasive administration options. Here, we present a buccal peptide delivery platform integrating electrostatic nanocomplexation, design of experiments (DoE)-guided optimization, and solid-state stabilization. Chitosan oligosaccharide (COS) was complexed with a model GLP-1 RA peptide molecule to generate monodisperse nanocomplexes (∼100 nm) with low polydispersity and a positive surface charge (∼+20 mV). Lyophilization preserved nanocomplex integrity during storage at 4 °C for at least one month, enabling dispersibility and retention of colloidal characteristics and GLP-1 RA secondary structure. Nanocomplexes exhibited minimal cytotoxicity in TR-146 cells at 1 mg/mL over 180 min. Mechanistic analyses demonstrated membrane lipid remodelling, dynamin-dependent endocytic involvement, and redistribution of tight junction and desmosomal proteins, supporting a model involving nanocomplex uptake leading to modulation of epithelial barrier properties. The nanocomplexes were then incorporated into a bilayer film composed of a pullulan/sodium carboxymethyl cellulose mucoadhesive layer and an Eudragit RLPO backing layer. GLP-1 RA permeation across porcine buccal mucosae from the nanocomplexes in solution reached ∼13% at 3 h (Papp ∼3.8 × 10-6 cm/s) while incorporation of complexes in bilayers yielded ∼3.4% permeation (Papp ∼1.2 × 10-6 cm/s) compared to the absence of flux for the GLP-1 RA in solution. These findings demonstrate that peptide nanocomplexes can be successfully incorporated into mucoadhesive films. This approach offers advantages over films comprising permeation enhancers.