Formation Of Carbonyl Sulfide Research Articles

Synthesis of methyl mercaptan from carbon oxides and H 2S with tungsten—alumina catalysts

The direct synthesis of methylmercaptan from carbon oxide(s) (CO or CO2), hydrogen sulfide and hydrogen was studied in the presence of tungsten-based catalysts. The optimization of W—K—Al 2O 3 catalysts makes it possible to obtain rather high activity and selectivity while keeping a fair stability. The main steps of the reaction are the formation of carbonylsulfide and hydrogenation of carbonylsulfide to methylmercaptan. The second step is generally the slow one, owing to the low hydrogenating properties of sulfide catalysts. Water has a strong inhibiting effect in the (CO 2, H 2S, H 2) reaction and the activity of the catalyst is lower than in the (CO, H 2, H 2S) reaction. ESCA experiments provide some important information on the behaviour of these catalysts during the sulfidation step of the catalytic reaction(s).

Studies of the metabolism of carbon disulfide by rat liver microsomes

Carbon disulfide has been examined as a substrate for the hepatic mixed function oxidase enzyme system. These studies have revealed that carbonyl sulfide is formed when carbon disulfide is incubated with rat liver microsomes in the presence of NADPH. No carbonyl sulfide is formed in the absence of NADPH. The formation of carbonyl sulfide is inhibited when the reaction is carried out in an atmosphere containing carbon monoxide. The other product of the reaction leading to carbonyl sulfide formation appears to be a highly reactive form of sulfur which covalently binds to the microsomal membrane. A chemical mechanism for the mixed function oxidase catalyzed metabolism of carbon disulfide to carbonyl sulfide is proposed.