To estimate the direct costs of care for patients with preeclampsia, from the third payer perspective, in a Colombian population affiliated to an insurance company in 2016. Cost description study that estimates costs of non-severe (NSP) and severe (SP) preeclampsia in pregnant women during 2016 using the Microcosting and standard costing technique. The average standard cost of preeclampsia was estimated and validated through a panel of experts. Unit costs of procedures and medications were determined based on the ISS 2001+30% and SISMED 2016 fees. Observed costs were taken from the insurer health care records. Mean and IC95% were used for the analysis. Costs were converted to US dollars 2016. We identified 979 cases of preeclampsia in 2016 (mean age: 25 years). The standard cost of an uncomplicated NSP event was $ 283 for vaginal delivery and $ 403 for cesarean section. The mean observed cost of NSP with complication was $ 999 [IC95%: $ 907- $ 1,090], of SP $ 1,837 [IC95% $ 1,679- $ 1,995], of Eclampsia (EC) $ 4,353 [IC95%: $ 3,211- $ 5,494] and of Other hypertensive disorders (OTHE) $ 964 [IC95%: $768- $1,159]. The highest cost of a complication of preeclampsia occurred in 39-49 years old women. The average inpatient length was 5 days. The average inpatient cost of a day of stay for was PNS: $ 208, PS: $ 301, EC: $ 389, and OTHE: $ 175. Preeclampsia represents a financial risk in health since the cost of an event represents more than 7 times the capitation payment unit that the insurer receives per affiliate. If we extrapolate these costs ($1,474) to the expected burden of disease (between 27,203 and 40,804 cases of Preeclampsia based on the 647,679 live births in Colombia in 2017), the economic burden would be between $ 40,106,544 and $ 60,159,078.