C1-C2 Facet Research Articles

Intra-rater and Inter-rater Reliability of the Commander Pressure Algometer in Greek Patients With Chronic Neck Pain.

Introduction Non-specific chronic neck pain (NSCNP) is a musculoskeletal disorder that affects 45%-54% of the general population. There is a strong correlation between patient-reported pain and mechanical pain pressure threshold (PPT) measured with an algometer. Purpose This study aims to investigate the intra- and inter-rater reliability of the Commanderalgometer in Greek NSCNP patients, in an urban primary care setting. Methods Thirty-three patients (22 women and 11 men) suffering from NSCNP (>3 months), the majority (42.4%) between the ages of 50 years and 59 years and overweight, were measured bilaterally both at the neck (mastoid, trapezius head-insertion and mid-portion, C5-C6 facet, insertion of levator scapula) and at the control areas (mid-deltoid and tibialis anterior) using the Commanderalgometer. Measurements were taken twice over a span of six days, by two raters, in a primary care setting. Intraclass correlation coefficient (ICC) statistics were used asmeasures of reliability (p = 0.05). Results Intra-rater reliability was "moderate to good" for both raters. ICCvalues for PPT at the seven bilaterally measured sites varied between 0.67 and 0.86 for the first rater (p ≤ 0.001) and 0.64 and 0.82 for the second rater (p ≤ 0.003). The inter-rater reliability was "moderate to excellent" (ICC = 0.68-0.92) in the first measurement (T1) and "moderate to good" (ICC = 0.68 to 0.89) in the second measurement (T2). Conclusion This study supports the intra- and inter-rater reliability of the Commander algometer in detecting reliably the mechanical PPT, in Greek NSCNP patients, as measured according to the procedures and methodology followed throughout this study.

C1-C2 Facet Joint Penetration by C2 Pedicle Screws: Influence of Local Anatomy, Bone Mineral Density, and Screw Length.

A challenge of C2 pedicle screw placement is to avoid penetration into the C1-C2 facet joint, as this may alter normal biomechanics and accelerate joint degeneration. Our objective was to clarify how local anatomy and surgical technique may relate to C2 pedicle screw penetration into the C1-C2 facet joint. C2 pedicle screws were inserted using a fluoroscopically assisted freehand technique. Independent fellowship-trained spine surgeons blindly reviewed intraoperative fluoroscopic and postoperative computed tomography (CT) images for evidence of facet joint penetration (FJP). C2 pedicle morphometry, the sagittal angle of the facet joint, axial and sagittal pedicle screw angles, and screw length were measured on the relevant CT images. A total of 34 patients fulfilled the study criteria, and a total of 68 C2 pedicle screws were placed. Eight screws (16%) penetrated the C1-C2 facet joint. The mean sagittal angle of the C1-C2 facet joint was significantly lower in the FJP group compared with the non-FJP group. The mean sagittal angle of the screws was significantly higher in the FJP group compared with the non-FJP group. The mean screw length was significantly greater for screws causing FJP compared with the non-FJP group. The mean axial screw angle was significantly lower in the FJP group compared with the non-FJP group. Pedicle width, length, height, and transverse angle were not significantly associated with FJP. Independent reviewers were able to identify FJP on intraoperative fluoroscopic imaging in 2 out of 8 cases. Lower sagittal angle of the facet joint, higher sagittal angle of the pedicle screw, and screw length >24 mm are associated with higher risk of C1-C2 FJP. When placing C2 pedicle screws under these conditions, caution should be taken to avoid FJP. Several anatomical and technical factors may increase the risk of C1-C2 FJP during placement of C2 pedicle screws using a fluoroscopically assisted freehand technique, underscoring the importance of preoperative planning and limiting screw length.

Indirect Ventral Brainstem Decompression by Posterior C1-C2 Distraction and Fixation for Basilar Invagination

Basilar invagination usually shows a decrease of clivus axis angle (CAA), which could give rise to progressive neural compression. Exploring a safe and effective fixation technique to achieve atlantoaxial stability and neural decompression remains necessary. In this study, we introduce a modified posterior C1-C2 distraction and fixation technique by which we obtained indirect ventral neural decompression and atlantoaxial stability in a series of patients with decreased CAA. Thirty patients of basilar invagination were enrolled in our series. All patients underwent thin-slice computed tomography (CT) scan, magnetic resonance imaging, and dynamic plain radiography examinations before surgery, at discharge and during the follow-ups. Posterior C1-C2 facet joint release and intraoperative reduction by fastening rods were performed in all patients. The CAA was measured on midsagittal CT scans. Patients' neurologic status was evaluated by the Japanese Orthopaedic Association score. No neurovascular injury and serious postoperative complication occurred in all patients. Complete ventral brainstem decompression was achieved in 20 patients and partial in 10 patients. The mean postoperative CAA significantly improved to 132.6 degrees compared with the preoperative 123.6 degrees (P < 0.01). The bone fusion was confirmed in all patients on the basis of the last follow-up spine CT scans. Indirect ventral brainstem decompression by posterior C1-C2 distraction and fixation is a safe and effective technique for treatment of basilar invagination.

Investigating the mechanical effect of the sagittal angle of the cervical facet joint on the cervical intervertebral disc

BackgroundFacet tropism is defined as the asymmetry between the left and right facet joints relative to the sagittal plane. Published clinical studies have found that facet tropism is associated with cervical disc herniation. However, the relationship between the facet orientation and the side of cervical disc herniation remains controversial. Therefore, this study used the finite-element technique to investigate the biomechanical effects of the sagittal angle of the cervical facet joints on the cervical intervertebral disc.ObjectiveThe biomechanical effects of the sagittal angle of the cervical facet joint on the cervical disc and facet joint were investigated using the finite-element technique.MethodsThe finite-element model was constructed using computed tomography scans of a 26-year-old female volunteer. First, a cervical model was constructed from C3 to C7. The model was verified using data from previously published studies. Second, the facet orientation at the C5–C6 level was altered to simulate different sagittal angles of cervical facet joints. Five models, F70, F80, F90, F100, and F110, were simulated with different facet joint orientations (70°, 80°, 90°, 100°, and 110° facet joint angles at the left side, respectively, and 90° facet joint angles at the right side) at the C5–C6 facet joints. In each model, annular fibres stress and facet cartilage pressure were studied under six pure moments and two combined moments.ResultsComparing the stress of the annulus fibres in flexion combined with right axial rotation and in flexion combined with left axial rotation in the same model, no difference in the maximum stress of the annulus fibres was noted between these two different moments in the F90 model, whereas differences of 12.80%, 8.84%, 14.95% and 33.32% were noted in the F70, F80, F100 and F110 models, respectively. The same trend was observed when comparing the maximum stress of the annulus fibres in each model during left and right axial rotation. No differences in annular fibres stress and facet cartilage pressure were noted among the five models in flexion, extension, lateral bending, left axial rotation, and flexion combined with left axial rotation in this study. However, compared with the F70 model in flexion combined with right axial rotation, the annulus fibres stress of the F80, F90, F100, and F110 models increased by 5.53%, 13.03%, 35.04%, and 72.94%, respectively, and the pressure of the left facet joint of these models decreased by 5.65%, 12.10%, 18.41%, and 25.74%, respectively. The same trend was observed in the right axial moment.ConclusionFacet tropism leads to unbalanced stress distribution on the annulus fibres at the cervical intervertebral disc. The greater the sagittal angle of the facet joint, the greater the annular fibres stress on this side. We hypothesised that the side with the larger sagittal angle of the facet joint exhibits a greater risk of disc herniation.

Post-traumatic Cervical Spondyloptosis Without Neurological Deficits: A Case Report

Background and Importance: Traumatic cervical spondyloptosis is a rare and severe situation, i.e., associated with disabling neurological deficits. Case Presentation: We described an unusual clinical presentation of cervical spondyloptosis in a 49-year-old man without neurological impairment and severe neck pain. Moreover, C6-C7 spondyloptosis was assessed two days after the trauma. X-rays, Computed Tomography (CT) scans and Magnetic Resonance Imaging (MRI) demonstrated a C6 bi-pedicular fracture, C6-C7 facet dislocation with complete ptosis of C6 vertebral body over C7 and without spinal cord injury. The patient was managed with an intra-operative 4 Kg traction and underwent a posterior decompression, with reduced fracture/dislocation by bilateral completed facetectomies at C6, and fusion from C4 to T3. Conclusion: This case report emphasized that sometimes cervical spondyloptosis may occur without neurological deficit symptoms. Prompt clinical recognition and surgical removal are essential to prevent serious complications in this respect.

Outcome of Surgery for Congenital Craniovertebral Junction Anomalies with Atlantoaxial Dislocation/Basilar Invagination: A Retrospective Study of 94 Patients

To evaluate the results of surgery for congenital craniovertebral junction (CVJ) anomalies with atlantoaxial dislocation (AAD)/basilar invagination (BI) and compare the results of transoral odontoidectomy and posterior fusion (TOO+PF) with only posterior fusion (PF) in patients with irreducible AAD/BI. All 94 patients with congenital CVJ anomalies with AAD/BI operated on during the 3-year study period (June 2013-May 2016) were included. Of these patients, 55 had irreducible AAD/BI and the remaining 39 had reducible AAD/BI. TOO+PF was restricted to patients (34/94; 36.2%) with irreducible AAD/BI when reduction and realignment by intraoperative C1-C2 facet joint manipulation were considered technically difficult and risky. The remaining patients with irreducible AAD/BI and all the patients with reducible AAD/BI (60/94; 63.8%) were managed with only posterior fusion. Poor preoperative Nurick grade, preoperative dyspnea/lower cranial nerve deficits, and syringomyelia were associated with significantly higher incidence of postoperative pulmonary complications. Follow-up ≥3 months (final follow-up) was available for 87 patients. Good outcome (Nurick grade 0-3) at final follow-up was noted in 90% (45/50) of the patients with irreducible AAD/BI and 91.9% (34/37) of the patients with reducible AAD/BI. Preoperative poor Nurick grade (4-5) was the only factor associated with poor outcome. No significant difference in perioperative complications, outcome, and fusion was noted between patients who underwent TOO+PF or only PF for irreducible AAD/BI. Many of the patients with congenital AAD/BI showed remarkable recovery after surgery. Preoperative poor Nurick grade (4-5) is associated with poor outcome. TOO+PF is a safe alternative treatment option for irreducible AAD/BI when only PF techniques are technically difficult/risky.

Prognostic significance of C1-C2 facet malalignment after surgical decompression in adult Chiari malformation type I: a pilot study based on the Chicago Chiari Outcome Scale.

The authors assessed the prognostic significance of various clinical and radiographic characteristics, including C1-C2 facet malalignment, in terms of surgical outcomes after foramen magnum decompression of adult Chiari malformation type I. The electronic medical records of 273 symptomatic patients with Chiari malformation type I who were treated with foramen magnum decompression, C1 laminectomy, and duraplasty at Mayo Clinic were retrospectively reviewed. Preoperative and postoperative Neurological Scoring System scores were compared using the Friedman test. Bivariate analysis was conducted to identify the preoperative variables that correlated with the patient Chicago Chiari Outcome Scale (CCOS) scores. Multiple linear regression analysis was subsequently performed using the variables with p < 0.05 on the bivariate analysis to check for independent associations with the outcome measures. Statistical software SPSS version 25.0 was used for the data analysis. Significance was defined as p < 0.05 for all analyses. Fifty-two adult patients with preoperative clinical and radiological data and a minimum follow-up of 12 months were included. Motor deficits, syrinx, and C1-C2 facet malalignment were found to have significant negative associations with the CCOS score at the 1- to 3-month follow-up (p < 0.05), while at the 9- to 12-month follow-up only swallowing function and C1-C2 facet malalignment were significantly associated with the CCOS score (p < 0.05). Multivariate analysis showed that syrinx presence and C1-C2 facet malalignment were independently associated with the CCOS score at the 1- to 3-month follow-up. Swallowing function and C1-C2 facet malalignment were found to be independently associated with the CCOS score at the 9- to 12-month follow-up. The observed results in this pilot study suggest a significant negative correlation between C1-C2 facet malalignment and clinical outcomes evaluated by the CCOS score at 1-3 months and 9-12 months postoperatively. Prospective studies are needed to further validate the prognostic value of C1-C2 facet malalignment and the potential role of atlantoaxial fixation as part of the treatment.

A novel classification and algorithmic-based management of craniovertebral junction osteoarthrosis.

Introduction:The objective of this study is to propose a novel classification and algorithmic-based management plan for craniovertebral junction osteoarthrosis (CVJOA).Materials and Methods:A retrospective study was done based on prospective database of radiological studies and clinical history. Twenty symptomatic patients (12 females and 8 males) with a mean age of 54.8 years were identified with CVJOA. These patients underwent either nonsurgical treatment only or surgical intervention and had follow-up of at least 14 months. Classification of CVJOA is based on coronal deformity, rigidity, stability, and two modifiers. The main surgical procedures done in the surgical arm of these patients included C1–C2 fusion, C1–C2 facet distraction and fusion, and unilateral subaxial facet distraction, and posterior column osteotomy.Results:All the twenty patients included in this study complained of either sub-occipital or upper neck pain and had radiological evidence of CVJOA. Seven patients improved with nonsurgical management and 13 underwent surgical intervention. Surgical recommendations for each type of CVJOA have been described with case examples, and algorithm for the management of CVJOA has been developed based on this study. Interobserver agreement on CVJOA classification was measured using kappa value statistics which showed moderate strength of agreement (0.467).Conclusion:This study describes a novel classification and management of CVJOA based on algorithm and current surgical recommendations for each type of CVJOA.

Endoscopic single stage trans-oral decompression and anterior C1 lateral mass and C2 pedicle stabilization for atlanto-axial dislocation.

Although most of the cases of atlanto-axial dislocation (AAD) and basilar invasion can be managed by posterior approaches in the recent times, anterior decompression with stabilization is required in selected patients who persist with irreducible AAD even after manipulation of the C1-C2 facet joint under general anesthesia. A single stage endoscopic trans-oral decompression and stabilization can be used in such patients. It has not been described so far to the best of authors' knowledge. This is indicated in irreducible AAD with the mandibular angle lying below the C2-C3 disc space. It is not a proper choice when the mandibular angle is above the C2-C3 disc space, there is involvement of the facet joint by trauma or any other pathologies, and if a posterior compression at the cervicomedullary junction persists. All patients should undergo pre-operative radiographs, computed tomography (CT) scan and magnetic resonance imaging with angiogram of the cranio-vertebral region. Utilizing this technique, an intra-operative satisfactory reduction of the dislocation with C1-C2 stabilization could be achieved in 3 patients, and 7 required an additional odontoid excision. Post- operative plain radiographs should be performed to assess for C1- C2 alignment and fusion at 3 and 12 months after surgery. All 10 patients of our series had an irreducible AAD and two had an additional basilar invasion. All patients improved from the pre-operative Ranawat grade 3A (n = 8) and 3B (n = 2) to post-operative grade 1 (n = 9) and 2 (n = 1) at a 3-12- month follow-up assessment. The average duration of the procedure and blood loss was 145 minutes and 75 ml, respectively. Endoscopic trans-oral single stage decompression and stabilization seems to be an effective and safe alternative in selected patients with AAD and basilar invasion.

Spinal injection of local anesthetic during cervical facet joint injection

Facet joint pain is a common source of non-radicular back pain worldwide. Non-surgical interventional modalities remain the mainstay in the treatment of facetogenic back pain and comprise the second most commonly performed interventional pain procedures in the USA. A 36 year-old man with chronic cervical pain secondary to C6-C7 facet arthrosis radiographically, underwent diagnostic local anesthetic bilateral facet joint injection under fluoroscopic guidance. The left side was injected uneventfully; however, 1-2min following injection of the right side the patient complained of unwellness and became very anxious. He referred paresthesias of the bilateral upper extremities, chest and upper abdomen. Physical examination showed sensory deficits roughly from C5 to T7 without motor deficits; resuscitation measures were not warranted. The deficits were completely resolved by 35-40min in the recovery area. Facet joint injections are a common and safe method of treating back pain secondary to facet arthropathy. Despite excellent safety profiles, rare and sometimes, life-threatening complications can occur. Our case hypothesizes intrathecal injection of local anesthetic during facet joint injection. Few reports have described similar situations. We hypothesize a mechanism of entry through the facet joint, given the proximity of the ligamentum flavum, and the intrathecal space to the anterior aspect of the facet joint. This report reinforces the need for resuscitation and airway management equipment to be readily available where interventional procedures are performed, as well as the need for adequate proficiency in airway management and resuscitation techniques in Pain Medicine training.

Six Different Vertebral Artery Configurations, in Three Subjects Commanding Different Approaches for C1-C2 Distraction and Fixation in Cases of CVJ Anomaly: A Case Series

Introduction There are various choices to fix up Atlanto-Axial dislocation (AAD) and Basilar invagination (BI), it may be Posterior only, Anterior only or Combined. Many surgeons refrain from “posterior only” approach of C1-C2 distraction (as described by Atul Goel and Lahiri) because of the fear of Vertebral artery (VA) injury and it's poorly understood course between C1, C2, and Occipital condyles. We describe details of preoperative work and subsequently adopted, customized surgical plans, as per VA configuration to distract &amp; fix the C1-C2 joint to achieve reduction in AAD and BI without harming the Vertebral artery. This case series covers most of the variations of VA around C1-C2 for learning purpose. After seeing this work up, many surgeons may allay their anxieties and take up this single stage corrective measure to achieve correction of deformities in cases of AAD &amp; BI. In the due course author will also explain different variations of Vertebral artery not only in different individuals, but also in same subject on either sides. We describe the adaptive surgical methods taken based on these data to avoid injury to VA, and still achieve a firm distraction and fixation at C1-C2 with this single stage. The technique can thus be extrapolated in various other cases of AAD and BI with hardly any exception. Material and Methods Three serial patients with an established diagnosis of Atlanto-axial dislocation and Basilar invagination are described. All three were evaluated with 3-D MPR CT with vertebral artery angiography (CTA-VA), and MRI at Cervico-medullary junction (MRI-CMJ). The VA in one subject was going through pedicle on one side and in another subject, it was going around the C1-C2 facet joint, while in another case it was entirely intra-spinal. The radiological evaluation was done in both pre and post operative period to describe anomalies of CVJ, different courses of VA and vectors thus used for potential instrumentation. Postoperative scans were used to see adequacy of fixation. Results There was a clear evidence of highly variable course in VA of all three subjects. There were different courses in right and left VAs as well, commanding different choices of instrumentation on both sides in a single individual. All patients achieved reduction of AAD &amp; BI and there was no injury to the vascular structure in question. They all improved in clinical signs and symptoms in the due course. Conclusion Authors conclude that it's mandatory to subject all patients to CT angiography in an order to view the Vertebral artery course wrt C1-C2 facets, which is not only variable in different individuals but also, on both sides in same individual, hence even in a single patient we may need different instrumentation to achieve the same goal. The authors also conclude that instrumentation at C1-C2 without CTA-VA is not only dangerous but can be fatal as well, hence instrumentation done without the above mentioned study should be considered a mandatory practice in the safest interest of patients and to achieve optimum and customized instrumentation.

Facet Joint Manipulation for Craniovertebral Junction Arthrodesis. Worth the Extra Effort?

Introduction The goal of arthrodesis is bone fusion, effected at the craniovertebral junction through onlay of either morselized iliac crest autograft (ICAG), or posterior structural unicortical ICAGbetween posterior elements. As an alternative, facet manipulation (FM) with C1-C2 or C0-C1 facet decortication and “jamming” of bone spacers into the articular space (C1-C2) has been described. We describe a series of 79 cases of surgical fusion of at least 1 component of the CVJ. FM was used in 65 cases requiring arthrodesis. Among these, we describe 14 cases using cages placed in the atlanto-axial joints (Cage assisted facet arthrodesis CAFA). To examine the efficacy of FM, we look specifically at CT documented fusion, and time to fusion using this technique. Material and Methods Retrospective review of medical records of 88 patients undergoing posterior arthrodesis of the craniovertebral junction (CVJ) at our unit from May 2004 to December 2013 was performed. 4 patients were excluded in case of early postoperative death (up to 30 days after the surgery). 5 patients had insufficient radiological follow-up data (follow-up &lt; 6 months). Construct length is detailed in Table 1 . Fusion – pseudarthrosis. Fusion was considered successful on CT if there was visible bridging trabeculations with or without bony remodeling and callus formation, across at least one of C1/C2 facets, and absence of pseudoarthrosis. Criteria for pseudoarthrosis were construct failure, or bone lucency around the screws. Time to fusion was defined as months between surgery and the earliest radiological assessment confirming solid fusion. Results Fusion rate and time to fusion. Sixteen patients were not considered for fusion analysis ( N = 6 not grafted), or insufficient follow-up ( N = 10). A solid fusion was achieved in 55 (87.3%) patients. Fusion rate was strongly associated with age. [Table: see text][Figure: see text] Conclusion Many techniques are used to achieve solid bony fusion in the upper cervical spine. Facet manipulation, first described by Goel should be the ideal fusion bed but has not been widely used. We report our experience using FM as a fusion technique to highlight its usefulness as a primary means of achieving fusion. It exploits the weight bearing part of the spine, the volume of bone graft materiel is very small compared with other techniques, it can be used when there are no posterior elements. Cage assisted facet arthrodesis (CAFA) may accelerate time to fusion, and may enhance fusion rates.

Distraction Arthrodesis of the Atlantoaxial Facet Joint with Preservation of the C2 Root for the Management of Intractable Occipital Neuralgia Caused by C2 Root Compression

Introduction Vertical collapse of the C1-C2 facet joint may cause narrowing of the C2 root foramen with root compression, resulting in severe occipital neuralgia. The purpose of this study was to evaluate the prospectively collected outcomes data of a distraction arthrodesis surgical group (Study group) in comparison to a Control group in a non-randomized design. Material and Methods The Study group underwent intraoperative skeletal traction, preservation of the C2 nerve roots, facet joint distraction and insertion of a bone block and cancellous bone into the joint along with posterior fusion, and segmental screw fixation using posterior C1 arch screws instead of lateral mass screws. The Control group had C2 root transection with C1-C2 segmental screw fixation and arthrodesis. Inclusion criteria for both groups were (1) occipital neuralgia caused by C2 root compression confirmed by clinical manifestation and imaging studies including radiographs, CT scan, and MRI, (2) intractable pain (VAS≥7) unresponsive to nonoperative treatment, and (3) follow-up period ≥12 months. We compared the preoperative and postoperative 10-point VAS scores for occipital neuralgia and neck pain; NDI; and JOA scores and recovery rates. Results There were 15 patients in the Study group and 8 in the Control group. All had facet joint destruction and/or collapse caused by underlying disorders including rheumatoid arthritis (Study group: 5 ; Control group: 3), rheumatoid arthritis with odontoid nonunion (2, 0), odontoid nonunion (3, 1), unifacet spondylosis (3, 2), os odontoideum (2, 1), and cerebral palsy (0, 1). There was no significant difference in age (61 ± 6, 62 ± 9), gender (4 and 3 men, respectively), and the number of cases with accompanying myelopathy (5, 2) between the 2 groups. The follow-up period averaged 21 ± 12 versus 33 ± 25 months, respectively. There was no significant difference in the VAS score for the preoperative occipital neuralgia (8.2 ± 0.9, 7.9 ± 0.6, p = 0.39). However, it was significantly lower in the Study group at 1, 3, 6, and 12 months postoperatively (p = &lt;0.01, respectively). At 12 months, the VAS was 0.4 ± 0.6 versus 2.5 ± 2.6 ( p = 0.01). In the Study group, all patients had little or no pain (VAS ≤2) while 2 patients (25%) in the Control group were still on medication (Gabapentin) with moderate to severe pain (VAS 4 and 8 respectively). There was no significant difference in preoperative and postoperative VAS scores for neck pain, NDI, and JOA scores and recovery rate, since these values are minimally influenced by occipital neuralgia. Conclusion Our results suggest that our novel technique of distraction arthrodesis can be an effective option for the management of intractable occipital neuralgia caused by C2 root compression. Prospective randomized studies are required for better evaluation.

Neck-Tongue Syndrome.

Neck-tongue syndrome (NTS) is a headache disorder often initiated by rapid axial rotation of the neck resulting in unilateral neck and/or occipital pain and transient ipsilateral tongue sensory disturbance. In this review, we examine reported cases of NTS since its initial description in 1980 to highlight the significance of this condition in the differential diagnosis of headache in patients presenting with neck pain and altered tongue sensation. The anatomical basis of NTS centers on the C1-C2 facet joint, C2 ventral ramus, and inferior oblique muscle in the atlanto-axial space. NTS may be categorized as complicated (secondary to another disease process) or uncomplicated (hereditary, related to trauma, or idiopathic). Diagnosis is based on clinical suspicion after a thorough history and physical without a pathognomonic radiologic finding. It is typically treated conservatively with medications, local injections, immobilization with cervical collars, or physical therapy; rarely is surgical intervention pursued.

Modified technique of transoral release in one-stage anterior release and posterior reduction for irreducible atlantoaxial dislocation

BackgroundOne-stage anterior release and posterior reduction is one of the most effective methods for irreducible atlantoaxial dislocation. However, the criteria of appropriate tissue release for successful posterior reduction is yet to be confirmed. Hence, an assistant technique using the transoral approach to verify satisfactory release is required. To evaluate the efficacy of the modified technique of transoral release for irreducible atlantoaxial dislocation (IAAD) with patients underwent one-stage anterior release and posterior reduction. MethodsBetween January 2009 and June 2014, 23 consecutive patients diagnosed with IAAD free from bony union between the C1–C2 facet joints on reconstructive computed tomography scan underwent one-stage anterior release and posterior reduction after no response to 2 weeks of skull traction. During transoral release, an elevator was used as a lever repeatedly to confirm a 3–5 mm bilateral joint space between the lateral masses of the atlas and axis. The release was accomplished since a 3–5 mm joint space was achieved. After anterior release, posterior reduction and instrumented fusion were subsequently performed. ResultsAll patients were observed for an average of 18 (range 6–50) months. Nineteen of 23 patients achieved complete reduction while four had an incomplete reduction. Significant differences in pre- and postoperative JOA scores and cervicomedullary angle (CMA) were found. Twenty-one patients presenting with myelopathy had a JOA score of 12.9 at final follow-up, improved from 7.8 before surgery. The mean CMA improved to 143.5° postoperatively from 101.8° preoperatively. Bony fusion was confirmed in all cases under radiologic assessment during follow-up; there were no instrument failures. ConclusionThe modified technique of transoral release provides appropriate criteria for anterior release, to achieve good posterior reduction without excessive tissue release or intraspinal manipulation, proving its value as an assistant technique in one-stage anterior release and posterior reduction for IAAD.

Distraction Arthrodesis of the C1-C2 Facet Joint with Preservation of the C2 Root for the Management of Intractable Occipital Neuralgia Caused by C2 Root Compression.

Prospective observational cohort study. To compare the outcomes of our new technique, distraction arthrodesis of C1-C2 facet joint with C2 root preservation (Study group), to those of conventional C1-C2 fusion with C2 root transection (Control group) for the management of intractable occipital neuralgia caused by C2 root compression. We are not aware of any report concerning C2 root decompression during C1-C2 fusion. Inclusion criteria were visual analogue scale (VAS) score for occipital neuralgia 7 or more; C2 root compression at the collapsed C1-C2 neural foramen; and follow-up 12 months or more. The Study group underwent surgery with our new technique including (1) C1-C2 facet joint distraction and bone block insertion while preserving the C2 root; and (2) use of C1 posterior arch screws instead of conventional lateral mass screws during C1-C2 segmental screw fixation. The Control group underwent C2 root transection with C1-C2 segmental screw fixation and fusion. We compared the prospectively collected outcomes data. There were 15 patients in the Study group and 8 in the Control group. Although there was no significant difference in the VAS score for the occipital neuralgia between the 2 groups preoperatively (8.2 ± 0.9 vs. 7.9 ± 0.6, P = 0.39), it was significantly lower in the Study group at 1, 3, and 6 months postoperatively (P < 0.01, respectively). At 12 months, it was 0.4 ± 0.6 versus 2.5 ± 2.6 (P = 0.01). There was no significant difference in improvement in the VAS score for neck pain and neck disability index and Japanese Orthopedic Association recovery rate, which are minimally influenced by occipital neuralgia. Our novel technique of distraction arthrodesis with C2 root preservation can be an effective option for the management of intractable occipital neuralgia caused by C2 root compression.

Trends in Epidemiology and Management of Traumatic Type II Odontoid Fracture: Experience in Latin America

Introduction Odontoid fractures (OF) are frequent in the trauma population, and there is no universally accepted single method of management. The objective of this study was to evaluate the epidemiology and management of type II OF in Latin America treated either with rigid cervical orthosis or surgery. Patients and Methods A total of 83 patients treated conservatively or by surgery were enrolled in this retrospective study. Medical charts, imaging studies, and outcomes of patients were analyzed in the pretreatment period and at the last medical evaluation. The fractures were assessed using conventional radiographs, three-dimensional computed tomographic (3D-CT) scans, and magnetic resonance images. Fracture gaps, the direction and the degree of displacement of the odontoid process, the fracture line anatomy, the degrees of atlantoaxial instability, the comminuted fracture, and the surface contact area were analyzed. The decision for operative or nonoperative treatment was based on anesthesia risk, and patient's choice of the nonoperative treatment. The nonoperative management generally consisted of a rigid cervical orthosis for 3 months. The type of surgery to be performed was chosen by the surgeon. The solid bony union was defined as the presence of bony bridges and the definite continuity of cortical bone. Fibrous union was considered present when no degree of motion was evident in dynamic radiographs despite persistent cortical bone discontinuity within a fracture gap on 3D CT scans. Nonunion was defined as a definite fracture gap with abnormal motion of the fractured dens on dynamic radiographs and on a 3D CT scan. Results A total of 83 patients were included in this study. The patients were 78.3% men, the mean age = 44.98 ( ± 23.20 years) years. Traffic accidents (66.3%) were the most common cause of trauma. The main symptom was pain (85.5%) in the posterior cervical region. The median time elapsed from accident to surgery was 7 days (P25: 2/P75: 27.5). Median follow-up was 23.66 ( ± 25.43 months) months. Conservative treatment with cervical orthosis, for example, Miami J collar or halo-vest was used in 20.5% of the cases. Odontoid screw technics (57.6%) were the most common surgical treatment adopted as primary surgical treatment. Symptomatic nonunion was observed in two cases with conservative treatment and three cases after odontoid screw fixation. All the patients were referred to posterior C1–C2 fixation. The posterior fixation tended to be used after conservative failed therapy, after nonunion anterior screw surgery, and in fractures with greater displacement. The most common radiological feature was no displacement of the odontoid process in relation to the body of C2, horizontal fracture line, gap fracture &lt; 2 mm, no subluxation across each C1–C2 facet joint and no comminuted fracture. Conclusion The patients treated nonoperatively with a rigid collar may have an overall favorable outcome compared with surgical treatment. A well-designed prospective study is needed to better elucidate optimal treatment algorithms from both an outcomes and cost-effectiveness perspective.

Bilateral Facet Dislocation with Neural Compression from an Avulsed Posterior Longitudinal Ligament

Background and Importance: A review of the literature failed to show evidence of normal appearing posterior longitudinal ligament avulsion as a cause of spinal cord compression after bilateral cervical facet dislocations. We report a case of the posterior longitudinal ligament (PLL) avulsion causing spinal cord compression after bilateral cervical facet dislocation. Clinical presentation: A 93 year female presented with upper extremity numbness and bilateral C5-C6 facet dislocations. The patient was immediately taken for closed reduction and anterior cervical decompression with fusion (ACDF). After awake, closed reduction, an ACDF was immediately performed. After a complete discectomy procedure, the spinal cord could be visualized secondary to an absent PLL. A nerve hook was used to explore behind the C6 vertebral body to decompress the spinal cord. A segment of normal appearing posterior longitudinal ligament, which had avulsed from the superior aspect of C5, was found folded behind the C6 vertebra causing cord compression. There was no herniated disk material discovered. Conclusion: In addition to herniated disk material, avulsed PLL is another potential source of cord compression after closed reduction of cervical facet dislocations and surgeons must be aware of this possible source of compression while exploring and decompressing the spinal canal. This case study elucidates that the PLL is a potential cause of spinal cord compression after traumatic bilateral cervical facet dislocations.

Aspirin Versus Heparin for Management of Cerebellar Stroke After Vertebral Artery Dissection Following C1-C2 Fracture-Dislocation: A Case Report.

Vertebral artery dissection (VAD) in the setting of a C1-C2 fracture-dislocation occurs in up to 20% of cervical spine trauma cases1-4. In young persons, it is one of the leading causes of ischemic stroke in the cerebellum5,6. It is important to recognize the signs of cerebellar and brain-stem infarctions in patients with cervical trauma and to initiate appropriate treatment. There is considerable controversy regarding the optimal course of treatment following a VAD7. We report a case of a patient with a unilateral VAD following a C1-C2 fracture-dislocation after falling from a horse. The patient was managed with heparin anticoagulation and subsequently developed a large retroperitoneal hematoma, a known complication of anticoagulation. We also review the current literature and guidelines regarding the clinical management of these patients. The patient was informed that data concerning the case would be submitted for publication, and she provided consent. A sixty-seven-year-old woman was admitted to the emergency department after falling off a horse from a height of approximately six feet and landing on her back. She reported immediate and persistent neck pain and an inability to turn the neck, but demonstrated no neurological deficits. Computed tomography (CT) of the neck showed a rotatory subluxation of C1 on C2 and a left C1-C2 facet dislocation with an associated avulsion fracture (Figs. 1-A through 1-D). The distal segments of the left vertebral artery beyond the fracture site were not visualized by magnetic resonance (MR) angiography, which is consistent with vessel compression (Figs. 2-A through 2-F). Fig. 1 Figs. 1-A through 1-F CT of the cervical spine showing the C1-C2 vertebral fracture-dislocation. Figs. 1-A and 1-B Neck CT prior to reduction. The severity of the rotatory deformity can be seen on the three-dimensional CT reconstructions. The overlapping axial CT …

Atlantoaxial instability in acute odontoid fractures is associated with nonunion and mortality

Background contextOdontoid fractures are the most common geriatric cervical spine fractures. Nonunion rates have been reported to be up to 40% and mortality up to 35%, and poor functional outcomes are common. Atlantoaxial instability (AAI) is a plausible prognostic factor, but its role has not been previously examined. PurposeTo determine the effect of severe AAI on the outcomes of nonunion and mortality in patients with acute odontoid fractures. Study designRetrospective cohort/single institution. Patient sampleOne hundred twenty-four consecutive patients with acute odontoid fractures. Outcome measuresRates of nonunion and mortality. MethodsTwo independent blinded reviewers measured AAI using postinjury computed tomography scans. Patients were classified as having “severe” or “minimal” AAI on the basis of greater versus less than or equal to 50% mean subluxation across each C1–C2 facet joint. Rates of nonunion and mortality were compared using independent samples t tests and adjusted for age, displacement, and subtype using binary logistic regression. ResultsOne hundred seven patients had minimal AAI and 17 had severe AAI. Mean follow-up was 4.4 months (standard deviation=4.6). Patients with severe AAI were more likely to experience nonunion (29% vs. 10%, respectively; p=.03) and mortality (35% vs. 14%, respectively; p=.03) regardless of treatment modality. Fracture displacement correlated with AAI (r2=0.65). When adjusted for patient age, the odds ratio of nonunion with severe AAI approached significance at 3.3 (95% confidence interval [CI]: 0.9–11.7). Mortality prediction with AAI approached a twofold increased risk (odds ratio=2.1; 95% CI: 0.6–6.8). In patients with Type-II fractures, the odds of mortality with severe AAI approached a threefold higher risk (odds ratio=3.3; 95% CI: 0.9–12.3). ConclusionsPatients with acute odontoid fractures and severe AAI may be more likely to experience nonunion and mortality, suggesting the possibility that aggressive management could be warranted. Further investigation with a large prospective study including patient-important functional outcomes is justified.