The non-Gaussian property of turbulence has been emphasized in some measured wind data. However, the classic Scanlan buffeting theory with the Gaussian distribution assumption of turbulence may cause errors in predicting the structural extreme response. In this study, a hybrid approach for predicting bridge's extreme buffeting response is proposed and validated, which considers multi-dimensional non-Gaussian random variables. Then the extreme buffeting response of a cable-stayed bridge under the attack of non-Gaussian wind is investigated, where the in-situ measured wind data of Typhoon ‘Bailu’ is adopted. The sensitivity of extreme buffeting response to turbulence skewness and kurtosis is also analyzed. The study results show that the lateral and vertical buffeting displacements are in skewed distributions under the attack of Typhoon ‘Bailu’. Compared to the Gaussian wind assumption, the non-Gaussian typhoon decreases the lateral extreme response, while increases the vertical extreme response. The results from the sensitivity analysis reveal a strong correlation between the non-Gaussian intensity of component u and that of the lateral buffeting response. In addition, the lateral extreme buffeting response increases significantly with the skewness and kurtosis of component u at a high probability level.
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