Buccal Minor Salivary Gland Research Articles

Pleomorphic adenoma of the cheek: a case presentation

BackgroundPleomorphic adenoma, also known as a benign mixed tumor, is the most common salivary gland tumor. The parotid gland accounts for 90% of the total, with the minor salivary glands accounting for 10%. Buccal minor salivary glands pleomorphic adenoma is extremely rare. It manifests as a painless, firm, slow-growing mass in most cases.Case presentationA pleomorphic adenoma in the buccal minor salivary glands was discovered in an adult 43-year-old female patient treated with wide surgical resection. A literature review of the PA of the cheek is stated.ConclusionIn the differential diagnosis of cheek masses, pleomorphic adenoma should be scrutinized. The remedy of choice is wide local excision with at least a 5-year follow-up.

A Single Firm Nodule of the Upper Lip: A Case Report

Canalicular Adenoma (CA) is a benign accessory salivary gland neoplasm. It represents less than 1% of salivary gland tumors. It occurs generally on the upper lips in female patients over 50 years of age. We report a case of canalicular adenoma that arose from buccal minor salivary glands of the upper lip without any symptomatology. Clinically, CA appears as an often single firm mass of 1cm, sparing the main salivary glands which is not pathognomonic of canalicular adenoma. Treatment of choice is enucleation to rule out many differential diagnoses that may present clinically as an asymptomatic nodule. Recurrences are rare. Histological features are characteristic and usually allow a definitive diagnosis to be made with confidence. However, many differential diagnoses remain to be ruled out.

A Single Firm Nodule of the Upper Lip: A Case Report

Canalicular Adenoma (CA) is a benign accessory salivary gland neoplasm. It represents less than 1% of salivary gland tumors. It occurs generally on the upper lips in female patients over 50 years of age. We report a case of canalicular adenoma that arose from buccal minor salivary glands of the upper lip without any symptomatology. Clinically, CA appears as an often single firm mass of 1cm, sparing the main salivary glands which is not pathognomonic of canalicular adenoma. Treatment of choice is enucleation to rule out many differential diagnoses that may present clinically as an asymptomatic nodule. Recurrences are rare. Histological features are characteristic and usually allow a definitive diagnosis to be made with confidence. However, many differential diagnoses remain to be ruled out.

Labial and buccal minor salivary glands of the dog - location, three-dimensional arrangement and histology.

ObjectiveTransplantation of minor salivary glands (MSGs) to the conjunctiva is a treatment option for patients suffering from dry eye disease. As there is not enough information about labial and buccal MSGs in dogs, the aim of this study was to provide evidence of the presence of these glands and to investigate their spatial arrangement and excretory ducts.MethodsThe oral mucosa of the lower lip of 4 dogs and the whole lower jaw of 1 dog were used for histological and microCT analysis. Presence, number, volumes and the tissue depth of MSGs were assessed.ResultsHistological analysis showed that compact tubulo‐acinar glands were located in the submucosal connective tissue. MicroCT images revealed that 9 to 21 MSGs were arranged in a single row at the level of the dental alveolae. The volume of the MSGs increased from rostral to caudal and the total volume of glandular tissue per animal ranged from 35.01 mm3 to 549.43 mm3. The mean tissue depth of MSGs ranged from 0.57 mm to 1.37 mm (upper surface of glands) and between 1.43 mm and 3.09 mm (lower surface of the glands). Excretory ducts left the dorsal part of the glands and ran in dorso‐rostral direction.ConclusionsThe location, number and volume of the labial and buccal MSGs in the dog could be detected and described using microCT scans and histology. The present results can provide valuable information for future transplantation of labial MSGs as therapeutic measure against keratoconjunctivitis sicca.

Juvenile pleomorphic adenoma of the cheek: Report of a rare case and literature analysis

Abstract Purpose The aim of this paper is to describe a rare case of children with pleomorphic adenoma in buccal minor salivary gland and present a brief review of the previous cases in the literature. Methods Research was conducted in the PubMed/MEDLINE/Google Scholar databases. The research was supplemented with a manual search to identify related published articles in dental journals. Results Articles published from 1986 onwards, in English language with full texts, were selected. Our search revealed that only 6 cases of children with pleomorphic adenoma in cheek (including pleomorphic adenoma arising from accessory parotid gland) were reported in the last 34 years. This paper also reports a case of pleomorphic adenoma on the cheek in a 10-year-old girl. The mass diagnosed with Ultrasonography was removed by wide local excision and no recurrence has been noted with a follow-up period of 14 months. Conclusion Salivary glands tumors are very rare in the pediatric age group, and rarely in minor salivary glands. Proper examination and assessment with preoperative imaging are necessary for its diagnosis. Pleomorphic adenoma should be included in the differential diagnosis of cheek lesions in young and adult patients. The possibility of late recurrences and malignant transformation should be regarded, thus prolonged follow-up is essential.

An unusual occurrence of Pleomorphic adenoma involving the buccal minor salivary gland - A case report and literature review

An unusual occurrence of Pleomorphic adenoma involving the buccal minor salivary gland - A case report and literature review

Pleomorphic Adenoma of Buccal Minor Salivary Gland: A Case Report

Salivary gland tumors are relatively uncommon tumors, accounting approximately 3-10% of head and neck neoplasm. Most of them are benign and pleomorphic adenoma is the commonest among them that involves both major (90%) and minor (10%) salivary glands. The most predominant site of pleomorphic adenoma is palate; however, it may occur in any part of oral cavity like lip, floor of mouth, tongue, tonsil, pharynx, retromolar area and nasal cavity. Mucosa of cheek (4%) is an extremely rare site. A case of 25 years young male is reported here possessing pleomorphic adenoma of buccal minor salivary gland that was presented to us with a mobile swelling over right cheek that found to be pleomorphic adenoma of buccal minor salivary gland after histopathological examination. Surgical excision was done by intra oral approach with adequate margins. Patient had an uneventful postoperative course and discharged same day on oral antibiotics.

Juvenile buccal pleomorphic adenoma: a rare case report

<p class="abstract">Salivary glands tumors are relatively uncommon in pediatric age group. Less incidence is expected in minor salivary glands of pediatric patients. In the buccal minor salivary glands only five cases reported as pleomorphic adenoma in english literature. Herein we present an 11 years old boy presented with right side buccal mass which is mobile on physical examination with normal overlying buccal mucosa. Histopathology revealed a pleomorphic adenoma. Such case is rare in this part of oral cavity especially in young age group. our case is the third youngest patients with buccal pleomorphic adenoma. Reporting it will add a material to the literature for further studies on such disease presentation<span lang="EN-IN">.</span></p>

頰部に発生した小唾液腺由来多形腺腫の1症例

頰部に発生した小唾液腺由来多形腺腫の1症例

Inverted ductal papilloma arising from the buccal minor salivary gland: A case report and immunohistochemical study

Oral inverted ductal papilloma is a rare, benign epithelial tumor that exhibits an endophytic growth pattern and is found almost exclusively in the minor salivary glands. We report on a case of inverted ductal papilloma in the buccal mucosa. We also performed an immunohistochemical study. The tumor cells were positive for cytokeratin and epithelial membrane antigen, while negative for calponin, S-100 protein, α-SMA, vimentin, and desmin. This result indicated that the lesion arises from the excretory duct near the oral mucosal surface but not the myoepithelial cells. In addition, Ki-67 labeling index of 3.96% indicated the low level of proliferation.

Metachronous Manifestation of Carcinoma Ex Pleomorphic Adenoma in a Buccal Minor Salivary Gland and the Contralateral Parotid Gland: A Case Report and Review of the Literature

Metachronous Manifestation of Carcinoma Ex Pleomorphic Adenoma in a Buccal Minor Salivary Gland and the Contralateral Parotid Gland: A Case Report and Review of the Literature

Mucosa-associated lymphatic tissue lymphoma of the lower lip in a child☆,☆☆

Mucosa-associated lymphatic tissue lymphoma of the lip in a child is a very rare clinical entity whose cause is poorly understood. We describe an 11-year-old boy who presented with a 5-month history of an asymptomatic nodule on the lower lip with the clinical appearance of a benign mucocele. After surgical excision of the lower lip lesion, lymphocyte phenotypic analysis and histologic examination of the specimen disclosed an extranodal marginal zone B-cell lymphoma of mucosa-associated lymphatic tissue type of the buccal minor salivary glands. Mucosa-associated lymphatic tissue lymphoma of the lip may clinically resemble a large mucocele. To prevent a delayed detection of lip mucosa-associated lymphatic tissue lymphoma, an incisional biopsy of large mucous cysts of the oral mucosa before marsupialization is recommended.

The buccal minor salivary glands as starting point for a metastasizing adenocarcinoma – report of a case

BackgroundWith the 2005 WHO classification of salivary gland tumours and its increasingly recognized diagnostic entities, the frequency of adenocarcinoma (NOS) has decreased significantly.Case presentationThis paper describes a fast growing adenocarcinoma (NOS), originating from the minor salivary glands of the left buccal mucosa with a rapid onset of multiple local and distant metastases, especially in the lung. A lung primary was unlikely as the tumour was characterized by positivity for cytokeratin 20 and negativity for the thyroid transcription factor-1 protein (TTF-1) in immunohistochemistry.ConclusionA rare case of an adenocarcinoma (NOS) of the minor salivary glands with a rapid development and an unfavourable clinical course is reported. It shows that additional immunohistochemical analysis can decisively contribute to determine the site of the primary tumour in cases with unknown primary.

Histomorphological investigation regarding to malignant transformation of pleomorphic adenoma (so-called malignant mixed tumor) of the salivary gland origin: special reference to carcinosarcoma.

Pleomorphic adenoma is the best-recognized tumor among those of salivary gland origin that also has the highest incidence. However, it is not uncommon for it to become malignant, and it has been noted that the frequency of malignancy increases as a result of the tumor persisting without being treated following the onset of adenoma. Carcinomatous components demonstrate various histological appearances, and in particular, there have been sporadic reports of carcinosarcoma in which malignant findings are not only observed in epithelial components, but in mesenchymal components as well. We conducted a histopathological study on cases of malignant-transformed pleomorphic adenoma, namely so-called malignant mixed tumor observed in our department. The subject cases consisted of a total of 19 cases registered in the diagnostic files of our department and included 12 males and 7 females. Age ranged from 46 to 87 (average 67.7) years old. The sites of occurrence consisted of the parotid gland in 17 cases, and palatal and buccal minor salivary glands in one case each. Histological types consisted of 7 cases of adenocarcinoma not otherwise specified, 3 cases of squamous cell carcinoma, 3 cases of salivary duct carcinoma, and one case each of polymorphous low-grade adenocarcinoma and epithelial-myoepithelial carcinoma, while the remaining were 2 cases of sarcomatoid carcinoma and 2 carcinosarcoma. We described herein their histological characteristics, discussed diagnostic problems in various instants in which each phenotype on this setting, and reviewed the literature, especially as to carcinosarcoma in contrast with those derived from other organs.

Ｃｒｙｓｔａｌｌｏｉｄの出現を伴った副耳下腺由来と思われる腺房細胞腫の１例

A case of acinic cell tumor of accessory parotid gland associated with “crystalloid” is presented. The patient was a 69-year-old female who was aware of a small mass of right buccal mucosa for 12 years. She consulted our clinic complaining of repeated swelling of the right parotid region. Oral examination revealed a submucosal elastic hard nodule beneath the right papilla parotidea. The lesion exhibited scattered radiopacity on roentgenogram. Under the clinical diagnosis of infected sialolithiasis in Stensen's duct, curettage was performed intra-orally. After two weeks, the submucosal nodule remained unchanged, then the lesion was excised along with the papilla parotidea under local anesthesia. Stensen's duct involved with the capsulated spheroid tumor was sacrificed and the proximal stump of the duct was sutured to the buccal mucosa. The patient recovered well after surgery.The excised tumor was 15 mm in diameter, and histologically composed of eosinophilic cuboidal cells organizing tubular or acinar structure with poor fibrous stroma. Capsular structure with thin fibrous connective tissue was evident. Characteristic “crystalloid”, which is occasionally found confined in the parotid gland and the origin of which is not known, as well as psammorna body were scattered throughout tumor, and some of the crystalloids had cores consisting of psammoma body. But, there was no sialolith in the specimen. Histopathological diagnosis was acinic cell tumor.The origin of the tumor in tins case was speculated to be accessory parotid gland rather than buccal minor salivary gland upon consideration of findings such as the anatomical relationship between the tumor and Stensen's duct, and identified crystalloid in the tumor. This is the first case reporting the existence of crystalloid in acinic cell tumor.

穿刺吸引細胞診の術前診断で判明した頬腺由来腺房細胞腫の１例

58歳, 女性の小唾液腺 (頬腺) に発生したacinic cell tumor (腺房細胞腫) の1例の術前診断に, 穿刺吸引細胞診が有効であった症例の概要を報告した.小唾液腺に発生した本腫瘍では, 細胞診の報告例は皆無であり, 今回, その細胞診と既報されている耳下腺発生例の細胞診の対比から, 本腫瘍における細胞診の所見を観察した.Papanicolaou染色標本には, 比較的単一で単調な形態の単離細胞や, 集塊または島嶼状の腫瘍細胞群の混在がみられた.円形または類円形の核は偏在し, 均一なクロマチン分布を示し, 核小体も目立たなかった.細胞質は類円形や, または, 偏在する核を要として扇形に広がるものが多く, 核から遠位の辺縁部は不明瞭化する傾向があった.緑色に好染する細胞質には, 分泌顆粒を思わせる小空胞様所見がみられた.N/C比は小さかった.

せん房細胞しゅの１例におけるｃｏｍｐｌｅｘ ｃａｒｂｏｈｙｄｒａｔｅｓ分泌の細胞化学的検索

The secretory function in an acinic cell tumor arising in buccal minor salivary gland was examined ultrastructurally and cytochemically by means of tannic acid uranyl acetate (TAUA) method, periodic acid-methenamic silver (PA-MS) reaction, thiamine pyrophosphatase (TPPase) reaction and acid phosphatase (AcPase) reaction.The tumor was composed mainly of secretory cells which revealed morphological similarity to serous cells seen in normal parotid and submaxillary glands, and undifferentiated cells probably derived from the reserve cells of the intercalated duct. Secretory cells showed also histochemical resemblance, since it was proved by periodic acid-Schiff (PAS) reaction and alcian blue staining that they contained neutral glycoproteins in their cytoplasmas.Compared to normal serous cells, secretory cells neither formed definitive lumina, nor showed apico-basal polarity. The Golgi complexes remained well-developed in the secretory cells and displayed an ultrastructure similar to that of normal serous cells. Within the secretory cells, TA-UA strongly stained Golgi stacks, the periphery of condensing vacuoles, matured secretory granules and luminal cavity. PA-MS reaction showed a stainability similar to that of TA-UA method. TPPase activity was localized in the Golgi stacks. AcPase reaction was detected in the Golgi stacks, lysosomes and secretory granules. Acpase activity within the secretory granules varied from scant to rather intense.These data may sugest that the complex carbohydrates synthesized in the Golgi stacks directly reaches the condensing vacuoles. The pathway of intercellular transport of carbohydrates appeared to be quite similar to that of some excretory cell types. On the other hand, the increase of lysosomal enzyme within the secretory granules may be presumably one of the characteristic findings in this secreting tumor.