Breast Size Research Articles

Insights into breast health issues in women's rugby.

World RugbyTM supports dedicated women's welfare, injury surveillance and medical/technical interventions, yet breast health has received limited attention. This article aims to provide insights into breast health issues in rugby, including breast impacts and injuries. We discuss how breast anatomy and position may be problematic in rugby. Breast volume relates to body size, which may be increasing in women's rugby, suggesting increased breast surface area and mass, potentially increasing injury risk. Breast health issues in rugby have been reported previously, with 58% of contact footballers (including rugby) experiencing breast injuries. There are damaging effects related to these breast health issues, with breast impacts often causing pain and swelling. Breast impacts may lead to haematomas, cysts and fat necrosis which can calcify over time making them difficult to distinguish from breast carcinoma, causing further investigation and anxiety. In sport, poor bra fit and insufficient support are associated with pain, skin strain and performance decrements. This article reports the potential implications of these breast health issues on performance in rugby. Recent breast-related projects supported by rugby communities may address recommendations identified in the literature for robust breast injury classifications, updated injury surveillance systems and prospective data collection on breast injury prevalence, severity and impact in rugby. These data should inform breast injury care pathways and intervention research, including evidence-based bra design. Understanding the implications of breast impacts on tissue properties, health and wellbeing is vital. Finally, data should inform rugby-specific breast education, raising awareness of this aspect of athlete health.

Optic disc characteristics on digital fundus photographs in Saudi children.

To assess the optic disc parameters in healthy Saudi children. This study recruited 85 children who were medically free, born full-term, cooperative, and aged 3-17 years. The children underwent a thorough ophthalmological examination (visual acuity, refraction post-cycloplegia, fundus photography) at the ophthalmology clinic of King Abdulaziz University Hospital, Jeddah. Fundus photographs obtained by a fundus camera were evaluated by the Retinal Size Tool program. Forty-eight participants were male (56.5%). The mean birth weight was 2.97±0.8kg and the median gestational age was 39 weeks (range, 37-40 weeks). The median areas of the neuroretinal rim, cup, and optic disc were 1.82mm2 (range, 0.84-2.83mm2), 0.47mm2 (range, 0.18-1.25mm2), and 2.33mm2 (range, 1.15-3.52mm2), respectively. The older age group had smaller neuroretinal areas compared to the younger age groups. The variables demonstrated no apparent correlation to axial length, refraction, or birth parameters. The cup size increased together with the optic disc (r=0.659, p<0.001). Sex and refraction did not correlate with any of the studied factors. This study yielded normative data for the optic disc parameters of healthy Saudi children. The data can be used as a reference in the pediatric ophthalmology clinic to aid the identification of optic disc abnormalities.

Metamorphosis of a Tall and Ugly Woman Through Plastic Surgery During a 7-Year Period: An Analysis of The Life and Loves of a She-Devil.

The aim of this study is to analyze the process of metamorphosis of a tall and ugly woman through plastic surgery as depicted in The Life and Loves of a She-Devil (1983) of Fay Weldon. The process of plastic surgeries and the psychology of the protagonist of this novel were analyzed. A highly unattractive woman (Ruth, 185cm) takes revenge on her husband (Bobbo, 175cm) and his attractive lover (Mary Fisher, 160cm). To transform her appearance, Ruth remodels her jaw, has her teeth extracted (2-jaw surgery or facial contouring surgery), straightens and trims her nose (corrective rhinoplasty), flattens her cheekbones (reduction malarplasty), reduces her breast size (reduction mammoplasty), and shortens both her arms and legs (limb reduction surgery). Following the series of surgeries, Ruth ultimately made herself look identical to Mary Fisher, her husband's lover. She believes her inadequacies stem from her body's failure to meet societal beauty standards, prompting her decision to "remake" herself. She declares, "I will be what I want, not what God ordained." Ruth's aspiration is not to acquire a new face but to attain the face of Mary Fisher. When confronted with pain and harm, Ruth does not waver but acknowledges it. "Of course it hurts. Andersen's little mermaid wanted legs instead of a tail. And, like her, I welcome it. I don't complain." In this study, we derived insights into why patients who want to change their entire bodies undergo plastic surgery, what these patients really want, and patients' attitudes toward the pain caused by surgical procedures.

Detectability of Breast Cancer Through Inverse Heat Transfer Modeling Using Patient-Specific Surface Temperatures

Abstract Breast cancer in women is a prevalent disease which takes over 680,000 lives each year worldwide. Early detection of breast cancer through screening has played a significant role in reducing the mortality rates. The current screening paradigm has shown the difficulties in detecting cancers for patients with dense breasts, small and deep tumors, and cancer types that are difficult to visualize. Infrared imaging (IRI) aided by advanced thermal analysis of the breast has shown great promise in detecting cancer using surface temperatures effected by a metabolically active and highly perfused tumor region. We previously developed an inverse heat transfer approach to detect the presence and absence of breast cancer using IRI, called the IRI-Numerical Engine. It was validated with 23 biopsy-proven breast cancer patients irrespective of breast density and cancer type at various tumor depths (0.95 cm to 5.45 cm from the breast surface). The current work is aimed to obtain the detectability limit of the IRI-Numerical Engine by testing the capability of detecting 10-20 mm tumors at various depths in patient-specific digital breast models. In addition, a study on the effect of tumor size, tumor location, breast shape, and breast size on the surface temperatures of patient-specific models was conducted to verify that an IR camera could capture these surface temperature distributions. The algorithm was able to detect the presence of a tumor at various depths, and deep tumors are detectable given the appropriate thermal sensitive IR camera.

Reduction mammoplasty, self-esteem, and sexual desire: A pre-post intervention study

Background/objectiveSexuality plays a significant role in social relationships and overall development. For women, the breasts hold considerable importance in sexual expression. Deviation from societal norms regarding breast size can lead to mental and sexual health issues. This study aimed to examine the impact of breast reduction surgery on self-esteem, body image, and sexual desire in women undergoing the procedure. MethodsA descriptive correlational study was conducted, involving 50 women who underwent reduction mammoplasty. ResultsRegarding pre- and post-surgical measurements, breast reduction surgery was associated with improvements in body image perception, as indicated by the BREASTQ reduction module, and both dyadic and solitary sexual desire. However, self-esteem remained unaffected by the intervention. Correlational analysis demonstrated a positive relationship between psychosocial well-being and other dimensions of body image, as well as sexual desire. Sexual well-being also correlated with breast and nipple satisfaction, along with dyadic sexual desire. Notably, age and self-esteem did not exhibit significant correlations with the variables studied. ConclusionThese findings suggest that breast reduction surgery can improve body image and sexual desire in women, but further research is needed to explore the long-term effects and the specific factors that contribute to these outcomes.

Factors influencing intraoperative conversion from double- to single-incision mastectomy with free nipple grafts in 352 transgender and non-binary patients

BackgroundDouble-incision mastectomy (DIM) with free nipple grafts (FNG) is a common technique employed in gender-affirming mastectomy (GAM), but is associated with a high scar burden. Intraoperatively, the surgeon may opt for a single-incision mastectomy (SIM) along the inframammary folds (IMF) to optimize aesthetic outcomes. This study sought to identify factors predictive of intraoperative conversion. MethodsFrom February 2018 to November 2022, TGNB patients who underwent GAM at a single institution were retrospectively reviewed. Data regarding patient characteristics, perioperative details, postoperative complications, and aesthetic satisfaction were collected. ResultsA total of 352 patients were identified. Median age and body mass index (BMI) were 25.0 years (IQR: 9.0) and 28.5 kg/m2 (IQR: 8.5), respectively. Most patients received IMF incisions (n = 331, 94.0%); of whom, 66 (19.9%) underwent intraoperative conversion from DIM to SIM with FNG. Larger breast cup-size (p < 0.001) and a greater degree of ptosis (p = 0.002) preoperatively were significantly associated with intraoperative conversion to SIM. There was no significant association between intraoperative conversion and the ratio of intermammary distance to the width of the chest wall (p = 0.086). Overall complication rates were significantly higher among patients with diabetes mellitus (p = 0.015) and a greater degree of ptosis (p = 0.018). 77.8% (n = 274) of patients were satisfied with their aesthetic outcome. NPWT usage was associated with higher rates of aesthetic satisfaction (83.6% vs. 77.8%; p = 0.005). ConclusionPatients with larger breast cup size and greater degree of ptosis should be counseled preoperatively that they may be at a higher risk of conversion to a singular incision.

A comparative study on quality of life of patients with breast cancer receiving subcutaneous gland resection combined with primary prosthesis implantation: Minimally invasive versus open surgery.

e12597 Background: Subcutaneous gland resection of the breast combined with primary prosthesis reconstruction is mostly used for reconstruction of early breast cancer (EBC) patients. In this study, we compared the long-term quality of life (QOL) of patients who underwent these procedures in a minimally invasive or open approach. Methods: The baseline data of EBC patients who underwent subcutaneous gland resection of breast combined with primary prosthesis reconstruction in a minimally invasive or open approach from 2008 to 2020 were retrospectively analyzed. The patients receiving minimally invasive surgery were regarded as minimally invasive group, and open surgery were regarded as open group. The BREAST-Q questionnaires were used to evaluate patients’ satisfaction with breasts, implants, animation deformity, psychosocial well-being, sexual well-being, physical well-being (chest) and breast sensation. Results: A total of 546 patients were enrolled, patients with local and regional recurrence, distant metastasis, death and prosthesis (44, 44, 22,12, respectively) were excluded, 423 patients were given questionnaires to evaluate their quality of life. Totally 226 questionnaires were recovered, with a response rate of 53.43%. Except 5 questionnaires with incomplete answers, 221 questionnaires were finally valid. There were 105 cases in the minimally invasive group, with an average follow-up time of 107.48 months (range 39-185 months), and 115 cases in the open group, with an average follow-up time of 77.97 months (range 36-188 months). The age was 43.0 [37.0, 47.0] years in all patients, 43.0[38.0, 47.0] years in the minimally invasive group and 42.5[36.8, 47.0] years in the open group. The patients in stage T1-2 accounted for 96.19% in the minimally invasive group and 97.42% in the open group, stage N0-1 accounted for 90.48% and 93.97, respectively. Prosthetic implant size showed no significant difference between two groups (220 [180, 240] cm3 vs 200 [180, 245] cm3, p=0.083). No significant difference was observed in patients’ race, education, marital status, income, job and breast size between the two groups ( p&gt;0.05). The scores of the minimally invasive group in satisfaction with breasts (54.0 [47.0, 59.0] vs 49.0 [44.8, 55.0], p&lt;0.01), animation deformity (70.0 [59.0, 100.0] vs 62.0 [57.0, 84.0], p=0.016), psychosocial well-being (66.0 [53.0, 93.0] vs 62.0 [49.0, 83.0], p=0.027), and physical well-being(chest) (48.0 [32.0, 56.0] 42.0 vs [32.0, 52.0], p=0.038) were significantly higher compared with the open group. There was no significant difference in implants, sexual well-being and breast sensation between the two groups. Conclusions: Minimally invasive subcutaneous gland resection combined with primary prosthetic implantation may improve postoperative quality of life in patients with EBC.

Personalized neoadjuvant strategy in ER positive and HER2 negative breast cancer to increase BCS rate (PLATO): A prospective, multicenter, phase II clinical trial.

595 Background: Neoadjuvant therapy significantly enhances the likelihood of breast-conserving surgery (BCS) in breast cancer patients. However, in ER-positive and HER-2 negative breast cancer, the response to neoadjuvant chemotherapy (NCT) is not as good as HER-2 positive or triple-negative breast cancer. In addition, with the evolution of multi-gene assays, many patients of this subtype may not require adjuvant chemotherapy. This study explores the potential of tailored neoadjuvant treatments (NCT or endocrine therapy (NET)) guided by 70-gene assay (Mammaprint, Agendia) to improve BCS rates in ER-positive/HER-2 negative breast cancer. Methods: A prospective, multicenter cohort study was conducted across four Korean centers from 2019 to 2023. Participants were clinical stage II-IIIA, ER-positive/HER2-negative breast cancer patients deemed unsuitable for BCS. Suitability was further verified by an independent three-surgeon panel using mammography or MRI. Out of 130 screened patients, 100 were enrolled. We analyzed 90 patients, excluding 10 cases; 2 with a basal type or HER2 type result in the blueprint, 7 who refused neoadjuvant therapy, and 1 who underwent surgery at another hospital. Before initiation of therapy, each surgeon recorded a target tumor size at which the surgeon would be able to do BCS considering location of the tumor and patient’s breast size. Based on the 70-gene assay results from core needle biopsies, high-genomic-risk patients received NCT (anthracycline + cyclophosphamide for 4 cycles, followed by 4 cycles of docetaxel), while low-risk patients underwent 16 weeks of NET with letrozole (±leuprolide for premenopausal women). Results: Out of the patients, 66 (73%) were high-genomic-risk and underwent NCT, while 24 (27%) received NET. Median tumor size was 3.7cm (85.6% clinical T2 and 14.4% T3/4). The primary endpoint, achieving the pre-established target tumor size for BCS, was reached by 70.0% (95% CI: 59.4-79.2%) of patients, significantly surpassing the set goal of 50.8% (a 15% increase from historical control). The rates were 74.2% for NCT and 58.3% for NET. The actual BCS rate was 58.9% overall (63.6% for NCT and 45.8% for NET). Clinically, 5.6% exhibited complete response (CR), 74.4% partial response (PR), 18.8% stable disease (SD), and 1.1% progressive disease (PD). Pathologic complete response (pCR) was achieved in 2.2% (all in the NCT group). No severe adverse events beyond expectations were observed. No pre-treatment clinical or pathological factor was significantly predictive for the BCS conversion. Conclusions: For ER positive, HER2 negative breast cancer patients initially ineligible for BCS, the use of pre-treatment multi-gene assays to guide selective NCT or NET could substantially increase BCS rates and reduce unnecessary chemotherapy. Clinical trial information: NCT03900637 .

Breast tumor detection using multi‐feature block based neural network by fusion of CT and MRI images

AbstractRadiologists and clinicians must automatically examine breast and tumor locations and sizes accurately. In recent years, several neural network‐based feature fusion versions have been created to improve medical image segmentation. Multi‐modal image fusion photos may efficiently identify tumors. This work uses image fusion to identify computed tomography and magnetic resonance imaging alterations. A Gauss‐log ratio operator is recommended for difference image production. The Gauss‐log ratio and log ratio difference image complement the objective of improving the difference map through image fusion. The feature change matrix extracts edge, texture, and intensity from each picture pixel. The final change detection map classifies feature vectors as “changed” or “unchanged” which has been mapped for high‐resolution or low‐resolution pixels. This paper proposes a multi‐feature blocks (MFB) based neural network for multi‐feature fusion. This neural network modeling approach globalizes pixel spatial relationships. MFB‐based feature fusion also aims to capture channel interactions between feature maps. The proposed technique outperforms state‐of‐the‐art approaches which have been discussed in detail in experimental results section.

Can machine learning predict the accuracy of preoperative planning for total hip arthroplasty, basing on patient-related factors? An explorative investigation on Supervised machine learning classification models.

BackgroundThe success of Total Hip Arthroplasty (THA) is influenced by preoperative planning, with traditional 2D approaches displaying varied reliability as well. The present study investigates the use of Supervised Machine Learning (SML) models with patient-related features to improve accuracy. MethodsPreoperative and perioperative data, as well as planning and final implant information, were obtained from 800 consecutive cementless primary THA, which was performed uniformly by a specialized surgical team. Six Supervised Machine Learning models were trained and validated using patient characteristics and implant data: Logistic Regression (LR), Linear Discriminant Analysis (LDA), K-Nearest Neighbors (KNN), Decision Tree (CART), Gaussian Naive Bayes (GN), and Support Vector Classifier (SVC). The models' ability to predict planning reliability and leg length disparity was evaluated. ResultsKNN performed better on the cup model (97.9 %), femur model (96.7 %), and femur size (99.2 %). SVM emerged as the model with the highest accuracy for cup size (60.4 %) and head size (62.1 %). CART had the best accuracy (99 %) when determining leg length discrepancy. ConclusionThe study demonstrates the utility of Supervised Machine Learning models, specifically KNN, in predicting the accuracy of preoperative planning in THA. The accuracy of these models, which are driven by patient-related characteristics, provides useful information for optimizing patients’ selection and improving surgical outcome.

Surgeon's Experience and Accuracy of Preoperative Digital Templating in Primary Total Hip Arthroplasty.

Preoperative planning has become essential in performance of total hip arthroplasty (THA). However, data regarding the effect of the planner's experience on the accuracy of digital preoperative planning is limited. The objective of this study was to assess the accuracy of digital templating in THA based on the surgeon's experience. A retrospective study was conducted. An analysis of 98 anteroposterior pelvic radiographs, which were individually templated by four surgeons (two hip surgeons and two orthopaedic residents) using TraumaCad® digital planning, was performed. A comparison of preoperatively planned sizes with implanted sizes was performed to evaluate the accuracy of predicting component size. The results of preoperative planning performed by hip surgeons and orthopaedic residents were compared for testing of the planner's experience. Femoral stem was precisely predicted in 32.4% of cases, acetabular component in 40.3%, and femoral offset in 76.7%. Prediction of cup size showed greater accuracy than femoral size among all observers. No differences in any variable were observed among the four groups (acetabular cup P=0.07, femoral stem P=0.82, femoral offset P=0.06). All measurements showed good reliability (intraclass correlation coefficient [ICC] acetabular cup: 0.76, ICC femoral stem: 0.79). The results of this study might suggest that even though a surgeon's experience supports improved precision during the planning stage, it should not be restricted only to surgeons with a high level of experience. We consider preoperative planning an essential part of the surgery, which should be included in training for orthopaedics residents.

The Benefits of Breast Massage: A Qualitative Study

Massage therapy has grown as a profession, and its use in the traditional medical setting is rapidly increasing. Massage therapy has been shown to have positive physical, psychological, and biochemical effects. The aim of this study is to review the reasons patients choose breast massage therapy and the benefits of breast massage therapy. Ten female patients of 18 years and older participated and completed the survey. Of the ten patients, the average age was 37.5 years. Most common reasons for choosing breast massage include: improve overall health (90%) and overall well-being (80%), relieve muscle tension (80%), reduce stress (70%), and increase size/firmness/elasticity (70%). Almost all patients reported an improvement in quality of life. Bust size increased for nine patients. Most patients reported a reduction in breast pain, reduction in breast swelling, increase in breast size, increase in breast firmness, improved skin elasticity, improved physical health, improved psychological health, and improved overall health and well-being. Breast massage has positive effects on physical and psychological health and well-being. Its use is increasingly sought after to improve breast health and overall health and wellness. Physicians, healthcare providers, and patients should consider breast massage therapy as complementary and alternative medicine.

Artificial Intelligence-Based Thermal Imaging for Breast Tumor Location and Size Estimation Using Thermal Impedance

Abstract Tumors can be detected from a temperature gradient due to high vascularization and increased metabolic activity of cancer cells. Thermal infrared images have been recognized as potential alternatives to detect these tumors. However, even the use of artificial intelligence directly on these images has failed to accurately locate and detect the tumor size due to the low sensitivity of temperatures and position within the breast. Thus, we aimed to develop techniques based on applying the thermal impedance method and artificial intelligence to determine the origin of the heat source (abnormal cancer metabolism) and its size. The low sensitivity to tiny and deep tumors is circumvented by utilizing the concept of thermal impedance and artificial intelligence techniques such as deep learning. We describe the development of a thermal model and the creation of a database based on its solution. We also outline the choice of detectable parameters in the thermal image, the use of deep learning libraries, and network training using convolutional neural networks (CNNs). Lastly, we present tumor location and size estimates based on thermographic images obtained from simulated thermal models of a breast, using Cartesian geometry and a scanned geometric shape of an anatomical phantom model.

Two-Dimensional Versus Three-Dimensional Preoperative Planning in Total Hip Arthroplasty

BackgroundPreoperative planning in total hip arthroplasty (THA) involves utilizing radiographs or advanced imaging modalities, including computerized tomography scans, for precise prediction of implant sizing and positioning. This study aimed to compare 3-dimensional (3D) versus 2-dimensional (2D) preoperative planning in primary THA with respect to key surgical metrics, including restoration of the horizontal and vertical center of rotation (COR), combined offset, and leg length. MethodsThis study included 60 patients undergoing primary THA for symptomatic hip osteoarthritis (OA), randomly allocated to either robotic arm–assisted or conventional THA. Digital 2D templating and 3D planning using the robotic software were performed for all patients. All measurements to evaluate the accuracy of templating methods were conducted on the preoperative computerized tomography scanogram, using the contralateral hip as a reference. Sensitivity analyses explored differences between 2D and 3D planning in patients who had superolateral or medial OA patterns. ResultsCompared to 2D templating, 3D templating was associated with less medialization of the horizontal COR (−1.2 versus −0.2 mm, P = .002) and more accurate restoration of the vertical COR (1.63 versus 0.3 mm, P < .001) with respect to the contralateral side. Furthermore, 3D templating was superior for planned restoration of leg length (+0.23 versus −0.74 mm, P = .019). Sensitivity analyses demonstrated that in patients who had medial OA, 3D planning resulted in less medialization of horizontal COR and less offset reduction. Conversely, in patients who had superolateral OA, there was less lateralization of horizontal COR and less offset increase using 3D planning. Additionally, 3D planning showed superior reproducibility for stem, acetabular cup sizes, and neck angle, while 2D planning often led to smaller stem and cup sizes. ConclusionsOur findings indicated higher accuracy in the planned restoration of native joint mechanics using 3D planning. Additionally, this study highlights distinct variances between the 2 planning methods across different OA pattern subtypes, offering valuable insights for clinicians employing 2D planning.

Hidden support for the lionesses: a breast/bra intervention

ABSTRACT Despite health and performance benefits of appropriate breast support in sport, elite women athletes’ knowledge of breasts/bras is poor leading to poor bra choices, breast pain and performance decrements. This multiphase intervention assessed breast/bra issues and preferences, individually prescribed sports bras and evaluated outcomes for the England Senior Women footballers. Breast/bra workshops were delivered to England players; all 36 completed pre-intervention surveys and breast/bra assessments, before being prescribed bras six weeks before European and World Championships (2022, 2023). 24 players completed post-intervention surveys. Pre-intervention outcomes identified poor knowledge, poor bra fit, many bra issues, and cultural sensitivities. Breast pain was prevalent (61%), with 25% reporting clinically significant breast pain. Post-intervention, players reported significant improvements with prescribed sports bras. 91% reported improvements in knowledge and benefiting from the intervention. This successful intervention provided an evidence-base for ongoing breast health initiatives with England Teams, plus roll-out to all levels of women’s football.

Exploring re-entrant auxetic silicone structures to design bra pads

Auxetic materials, known for their negative Poisson's ratio and unique form-fitting deformation, are proposed in this study for designing bra pads to accommodate different bra cup sizes. The deformation elasticity behaviour of re-entrant auxetic structures with a bow-tie shape, made of silicone elastomer, is systematically analysed for size accommodation and shape conformity, and compared with traditional polyurethane foam and spacer fabric used in bra pads. The results indicate that the auxetic structures exhibit desirable mechanical properties, including superior elasticity and stable deformation under tensile loading. Additionally, these structures facilitate 3D shape conformity to breast shapes, thereby improving overall bra fit. Amongst the 4 different unit cell dimensions studied, the auxetic elastomer with a cell size of 9.14 mm is the most promising candidate, which has superior elasticity, linear expansion, and excellent shape conformity. This auxetic elastomer enables increases in area from an A to D cup thus offering the potential to realize a one-size-fits-more concept. The findings provide the grounds for future research endeavours that aim to develop support in different areas of bras and optimize the arrangement of unit cells to enhance the functional aspects of bras.

Translation and validation of a Romanian version of the Breast Appreciation Scale (BrAS)

The 9-item Breast Appreciation Scale (BrAS; Swami et al., 2022) is a recently developed instrument that assesses a woman’s positive breasted experiences. To date, however, the psychometric properties of the BrAS have only been investigated in English-speaking women. Here, we report on the translation and validation of a novel, Romanian version of the BrAS. A total of 555 cisgender women from Romania completed a Romanian translation of the BrAS along with additional measures of body image and psychological well-being. Exploratory and confirmatory factor analysis identified a stable unidimensional model of the BrAS, with all nine items retained. Additionally, the Romanian BrAS evidenced complete invariance (i.e., through to latent mean invariance) across mothers and non-mothers, though mothers had higher observed scores than non-mothers. Evidence of convergent, concurrent, and incremental validity was very strong when based on observed BrAS scores, but slightly weaker when based on latent BrAS scores. In particular, greater latent breast appreciation was significantly associated with higher body appreciation, lower breast size dissatisfaction, and higher self-esteem. Overall, these results suggest that the psychometric properties of the Romanian BrAS are robust and that the instrument can be effectively deployed in this linguistic context.

Intraoperative live measurement of femoral head size for acetabular cup sizing: simple, accurate, and green!

Templating is the first step in achieving a successful total hip arthroplasty. We hypothesize that native head size is highly correlated with implanted cup size. Therefore, the purpose of this study is to look for a correlation between sizes of the intra-operative measurement of the femoral head and the implanted cup. This is a monocentric observational study conducted from December 2018 till January 2023. All patients admitted for a primary total hip arthroplasty were included and retrospectively reviewed. Intra-operative femoral head measurement, radiographic femoral head diameter, templated (planned) cup size, and definitive implanted cup size were recorded. The sample included 154 patients (85 female and 69 males) with a mean age of 66.2 ± 10.4years. There were 157 THA cases; 82 on the right side and 75 on the left side. The native head size and acetate template on digital radiographs were the most significantly positively correlated with cup size (P < 0.0001) while the radiological head size was significantly negatively correlated with cup size (P = 0.009). The implanted cup was on average 2 ± 2mm bigger than the native head size measured intra-operatively. The native femoral head diameter measured intra-operatively is a simple and reliable tool to help the surgeons choose the proper size of the acetabular cup, preventing complications during surgery hence optimizing results post operatively. This technique would contribute to a more ecofriendly orthopaedic reconstructive surgery.

Application of near-infrared spectroscopy to assess the effect of the cupping size on the spatial hemodynamic response from the area inside and outside the cup of the biceps.

Cupping therapy is a popular intervention for improving muscle recovery after exercise although clinical evidence is weak. Previous studies demonstrated that cupping therapy may improve microcirculation of the soft tissue to accelerate tissue healing. However, it is unclear whether the cupping size could affect the spatial hemodynamic response of the treated muscle. The objective of this study was to use 8-channel near-infrared spectroscopy to assess this clinical question by assessing the effect of 3 cupping sizes (35, 40, and 45 mm in inner diameter of the circular cup) under -300 mmHg for 5 min on the muscle hemodynamic response from the area inside and outside the cup, including oxyhemoglobin and deoxy-hemoglobin in 18 healthy adults. Two-way factorial design was used to assess the interaction between the cupping size (35, 40, and 45 mm) and the location (inside and outside the cup) and the main effects of the cupping size and the location. The two-way repeated measures ANOVA demonstrated an interaction between the cupping size and the location in deoxy-hemoglobin (P = 0.039) but no interaction in oxyhemoglobin (P = 0.100), and a main effect of the cup size (P = 0.001) and location (P = 0.023) factors in oxyhemoglobin. For the cupping size factor, the 45-mm cup resulted in a significant increase in oxyhemoglobin (5.738±0.760 μM) compared to the 40-mm (2.095±0.312 μM, P<0.001) and 35-mm (3.134±0.515 μM, P<0.01) cup. Our findings demonstrate that the cupping size and location factors affect the muscle hemodynamic response, and the use of multi-channel near-infrared spectroscopy may help understand benefits of cupping therapy on managing musculoskeletal impairment.

Abstract PO1-12-04: Exploring Factors Associated with Sexual Well-being and Breast Satisfaction Among Women with Early-stage Breast Cancer

Abstract BACKGROUND: Breast cancer affects not only physical health but also psychological and emotional well-being. Among the various aspects that impact the quality of life of breast cancer patients, sexual well-being and body image in terms of breast satisfaction play a crucial role. Unfortunately, these aspects are often overlooked and undervalued in healthcare, leading to inadequate care and support for breast cancer patients. This study delved into the factors that influence breast satisfaction and sexual well-being in early-stage breast cancer patients who have recently received a cancer diagnosis. We aim to offer providers a more patient-centered and comprehensive approach to breast cancer care. METHODS: This prospective questionnaire-based study screened 175 early-stage breast cancer patients recently diagnosed at a university-affiliated community hospital in Michigan from October 2022 to June 2023. Participants with a previous history of chemoradiation and advanced-stage breast cancer were excluded. Structured telephone interviews were conducted to obtain informed consent and assess patients' breast satisfaction and sexual well-being. Participants were interviewed after their recent breast cancer diagnosis and before undergoing surgical intervention. A validated BREAST-Q questionnaire was used, and their scores were converted to equivalent Rasch scores for interpretation (0=worst, 100=best). Pre-existing medical conditions, social history, and other variables were collected through electronic medical records review and confirmed by interview. Statistical analyses were performed using SPSS version 28.0, and a p-value less than 0.05 was considered statistically significant. RESULTS: Of 175 patients initially screened, 56 met the selection criteria. 75% (N=42) participated, while 25% (N=14) were excluded as they declined to participate or were unreachable via telephone. 81% were White, 14% were Black, and 5% were Hispanics. The cancer stages of the patients were Stage 0 (29.3%), I (48.8%), II (12.2%), and III (9.8%). The mean breast satisfaction score of participants was 67.1 (N=42), and the mean sexual well-being score was 44.6 (N=36). The study found that only the type of surgery was observed to be significantly related to the breast satisfaction of patients. Interestingly, patients who chose mastectomy had higher breast satisfaction scores (75.6 vs. 62.9, p&amp;lt; 0.05) and were relatively younger (59 years vs. 67 years, p&amp;lt; 0.05) than those undergoing lumpectomy. No other demographic factors (race, education, marital status, BMI), social history (smoking), bra size, or pre-existing medical conditions (hypertension, diabetes) were found to affect breast satisfaction among these patients. On the other hand, age had a negative correlation with sexual well-being (mean age=64 years, p&amp;lt; 0.05), while income had a positive correlation (mean income=$ 76,170 annually, p&amp;lt; 0.05). No other variables were significantly associated with patients’ sexual well-being. CONCLUSION: The study revealed that the patient's sexual well-being was significantly associated with age and income, while breast satisfaction was only related to the type of surgery. These findings underscore the importance of considering multiple aspects of a patient's life when designing a comprehensive treatment plan following a cancer diagnosis. By providing additional support and resources tailored to these specific needs, healthcare providers can enhance patients' overall quality of life and promote greater satisfaction with their treatment outcomes. Citation Format: Kim Abbegail Aldecoa, Yi Lee, Lisa Deptula, Chioma Mbionwu, Ewomamobuho Eto, Esentur Salamatov, Megan Frame, Andrea Briefs Ferris, Geetha Krishnamoorthy, Amy Kirby, Judie Goodman. Exploring Factors Associated with Sexual Well-being and Breast Satisfaction Among Women with Early-stage Breast Cancer [abstract]. In: Proceedings of the 2023 San Antonio Breast Cancer Symposium; 2023 Dec 5-9; San Antonio, TX. Philadelphia (PA): AACR; Cancer Res 2024;84(9 Suppl):Abstract nr PO1-12-04.