A systematic review and meta-analysis. Cage subsidence (CS) is a common complication following transforaminal lumbar interbody fusion (TLIF) surgery. This study aimed to identify and analyze risk factors associated with CS following TLIF. A comprehensive search was conducted across PubMed, Scopus, Embase, and Google Scholar for studies published up to March 31, 2024. Pooled odds ratios (OR), standardized mean differences (SMD), and 95% CI were calculated for each identified risk factor. Interstudy heterogeneity was evaluated using the I² statistic, and either a random-effects or fixed-effects model was applied as appropriate. Publication bias was assessed through funnel plots. Nine studies, comprising data on 1403 patients who had undergone TLIF, were included in the final analysis. Significant risk factors for CS included age (SMD=0.27; 95% CI: 0.12-0.41) and bony endplate injury (OR=7.52; 95% CI: 2.08-27.17). However, no significant associations were found with other potential risk factors, such as cage height, body mass index (BMI), bone mineral density, smoking status, diabetes, sex, center point ratio (CPR), disc height (preprocedure and postprocedure), or surgery location. This meta-analysis identified older age and injury to the bony endplate as significant risk factors for CS after TLIF. These findings may help inform clinical decision-making and guide risk stratification in patients considering TLIF.
Read full abstract- All Solutions
Editage
One platform for all researcher needs
Paperpal
AI-powered academic writing assistant
R Discovery
Your #1 AI companion for literature search
Mind the Graph
AI tool for graphics, illustrations, and artwork
Journal finder
AI-powered journal recommender
Unlock unlimited use of all AI tools with the Editage Plus membership.
Explore Editage Plus - Support
Overview
1275 Articles
Published in last 50 years
Articles published on Bony Injuries
Authors
Select Authors
Journals
Select Journals
Duration
Select Duration
1067 Search results
Sort by Recency