Back Bone Research Articles

IMPROVEMENT OF POWER QUALITY USING FUZZY BASED UNIFIED POWER FLOW CONTROLLER

The Electricity is contemplated as the back bone for the industrial revolution and in order to conclave the meeting of both industrial and household needs electricity needs to be at a larger transmission. For this paving of the electricity and also regulating the issues which are cascading on the power system something Flexible need to be adapted. Flexible Alternating Current Transmission Systems (FACTS) has been a promising aspect in terms of the power system performance analysis. In this paper a comprehensive analysis on the Unified Power Flow Controller (UPFC) which being one of the FACTS device is presented. Accordingly the UPFC for different cases is perceived using a Proportional Integral (PI) controller and a Fuzzy logic controller (FLC). The Fuzzy logic controller is introduced, developed by the MAMDANI method replacing PI controller on a transmission line under different power system operating conditions. MATLAB/SIMULINK was used in order to delineate the controller network. It was observed that the UPFC with the Fuzzy logic based control technique in lines of alleviating the power quality issues an superior performance than that of UPFC with the PI controller. It could be concluded that the Fuzzy logic controller (FLC) for mitigating the issues of power quality. Keywords— Flexible Alternating current transmission systems (FACTS), Unified Power Flow Controller (UPFC), Proportional integral, fuzzy logic, MATLAB/SIMULINK, Power system, Power Quality.

A Study On Emotional Intelligence and Employee Performance in Public Sector Banks in Kerala

ith the emergent development of globalization of the business world, organizations must adopt various sorts of strategies and additional procedures in comprehensive and pioneering way in order to achieve well-organized and effective work. Employees are the back bone of any organization and to make them work effectively, many strategies are being followed. Though, employees’ performance and effectiveness in the workplace depends on a number of factors such as financial support, educational background, job position and attitude etc. But, now leaders have also started giving consideration to Emotional Intelligence (EI) as one of the key element in organization’s success. EI is one of must-have skills and capabilities which are required by leaders and followers at workplace to encounter the environment changes and do as possible as they could to gain the organization commitments that could lead to organization’s success. Previous research exhibited that EI is also one of the important factor in organizational commitment and there is a strong relationship between emotional intelligence and job satisfaction and Employee performance with leads to organizational commitment. Hence, the higher employees’ EI scores, higher will be employee performance and his commitment towards organization. Employees with high developed Emotional Intelligence (EI) are proven to be more successful at workplace, because of the understanding of their emotions and why they behave in a particular situation in that way. In this study effect of emotional intelligence (EI) on employee performance in an organization has been investigated and the gap in the existing literature of Emotional intelligence has been identified. Assessing the reviews and analyses presented in this paper, it is expected that this review can be further referred in the new studies for the understanding of effect of emotional intelligence on employee performance.

Effect of Lifestyle Pattern and Cultural Practices on Vitamin D Status of Muslim Women in Coimbatore City

Muslim women follow unique lifestyle pattern influenced by cultural practices. Studies in Middle East countries showed high rate of vitamin D deficiency among Muslim women1. Hence, the present study aims to find the effect of lifestyle pattern and cultural practices on vitamin D status of Muslim women. Two hundred Muslim women between the age of 25 to 45 years were selected in Coimbatore city. Details regarding education, occupation, cultural dress, sunlight exposure, sunscreen usage and physical activity patterns were collected using a designed interview schedule. Clinical examination was conducted for signs and symptoms of vitamin D and calcium deficiency. Nineteen per cent of the women were between 25-30 years, 44 per cent were between 31-40 years and 37 per cent were between 41-45 years of age. Eighty eight per cent were house wives and 91.5 per cent of them wore cultural dress, among which 59 percentage wore chaddar in black colour. Sunlight exposure was less than 30 mins in 39.5 percentage of women. Seventy five per cent of them did not exercise. Back pain, bone loss, body pain and hair loss were prominent symptoms among the women. There was a significant association (P = 0.008) between sunlight exposure, type and colour of the cultural dress, back pain, pain in bone and bone loss. Hence, it may be concluded that exposure to sunlight at home may be recommended to improve vitamin D status of Muslim women.

WOMEN AND ARTS EDUCATION IN JAMMU AND KASHMIR: PROBLEMS AND PROSPECTS

Arts education plays a significant role in the development of society as well as nation. Arts education is classified into two main categories: visual arts and performing arts. Visual arts include drawing, paintings, sculpture etc. Performing arts includes music, theatre etc. Women are the back bone for the development of arts education as well as national development. Women are contributed more in arts education. Arts education is not as famous in India as it is famous in other states of the world. The reasons are many. The first objective of the paper is to study the problems faced by women in arts education. The second objective of the study is to study the remedial measures to overcome the problems faced by women in arts education. The main problems are as under: no government attention to arts education, no infrastructure facilities to arts education, less government jobs opportunities in arts education, less awareness programmes related to arts education, negative attitudes of parents towards arts education, no government arts institutions in Jammu and Kashmir union territory etc. This is a conceptual paper based on the reviews of various research papers, dissertations, theses, articles, newspapers, journals, university news and internet websites related to problems faced by women in arts education.

Changes in business processes - 21st century

In the present scenario aftet covid-19 the businesses have to shift their focus and look for new ways to run their busineses in order to sustain. The businesses has to ensure that they deliver their products to the cusotmers on time and extend their markets, in order to do this they have to focus on the processes like advertisement, direct marketing etc., and shfit towards online trends. The paper focuses mainly on the payment processes which is a back bone for tranformation like phone pay, google pay, paytm etc.,

A STUDY ON JOB SATISFACTION OF EMPLOYEES IN TAMIL NADU WITH SPECIAL REFERENCE TO TBF, KUMBAKONAM

Employee is a back bone of every organization, without employee no work can be done. Employed individuals spend a majority of their adult life making a living for themselves and their families. Objectives of the study. To study the job satisfaction of employees in TBFKumbakonam and to learn the factors influencing and affecting job satisfaction of employees in TBFKumbakonam. Descriptive and Conclusive in Nature of the research design adopted in this study.primary as well as secondary data have been used in this study.Primary data collected through structured questionnaire. Important findings of the study. It was found that almost all the respondents have registered their positive opinion about the experience they obtain in their work. Only a few respondents do not have any opinion and another few expressed that their rest interval is not adequate and inadequate facilities to attend their job. Suggested in this study, Redressing grievances, then and there to keep the employee and their colleagues relationship intact and provide relaxation techniques like yoga and meditation may be arranged by the organization. Conclude this study. As employees services are considered as emerging field, the problems of the employees will definitely affect their profession and so conflicts in all the aspects should be eliminated.

The Problems and Demands of Children in Indonesia for the Next Twenty Years

Indonesia as is the case with other developing countries has a "young" population of which 43% conists of a populatdon of underfifteen.
 Since we know that these children will be the back bone of our nation in the future, efforts to support the endeavour to promote child health will be very beneficial for a long term program.
 We ought to be happy that the long term health program in Indonesia is directed to the young and productive section of the community and attention is especially given to the low income section or to those in the rural areas.

Exploration the Dromos of Hermes at Hermopolis Magna

The dromos of god Thoth (Hermes) at Hermopolis Magna was the back bone of the ancient city of Hermopolis Magna, it ran from the east to the west and attracted all the city institutions at it’s both sides. This paper aims to highlight the historical and archaeological importance of the dromos through displaying the settlement planning and the major public place for different activities like healing, dream interpretation, religious celebrations, governmental declarations, and commercial activities. The archaeological remains alongside the dromos confirm its major role, so, the remains of the Gate of the Sun at the eastern side, passing to the exedra then to the komsterion which was near to the chapel of the royal cult, alongside the northern side of the dromos we could find the remains of the tertrastyli, also, the Bank of Athena. This study depends on analyzing methodology of the archeological sites of Hermopolis Magna, which locate the dromos from the north to the south of the city, but the Results of the study reveals that the dromos was running from east to west of Hermopolis Magna.

Impact of Macroeconomic Variables on Stock Returns: A Case Study from Karachi Stock Exchange

The main theme behind this research is to find out how different macroeconomic variables affect the returns of the Karachi stock exchange. The three variables like interest rate, inflation rate and exchange rate which are taken under consideration are the back bone of any economy and this impact the economy in different ways if some sort of fluctuations occurs in these variables. Fifteen years annul data from 1992 to 2007 is taken and multiple regression models applied on this data. The results are very significant and the strong correlation is found among dependent and independent variables which shows that the model is a strong model. The impact of interest rate, exchange rate and inflation rate are significant on the stock returns of KSE 100 index

Taxtation system in 21th century

Taxtation system is the back bone of economy.Economy can be run with the help of good economic and Taxtation system.Taxtation system provide the base of good economic map and way to devlopment.

Taxtation system is the back bone of economy.

Taxtation system is the back bone of the economy.No economic system can not run with out Taxtation system.

Fatigue reliability assessment of the new design of universal upright for the JCU Formula SAE car

The objective of this paper is to calculate fatigue reliability of the new design of universal upright for the James Cook University Formula SAE car. The upright design is the back bone of the unsprung mass on the car as it provides connection points for many necessary components. Several different forms of analysis were used to ensure the upright design is capable of handling the frequent loading from different load cases. The main form of analysis was computational modelling using finite element method (FEM) to determine and apply loads to the initial upright design. Using these results the upright was further optimised to save weight and improve cooling effects to the upright and surrounding components. Also, in order to maintain the minimum amount of reliability at a certain value, the number of variable components is defined at each time of inspection. The results showed that reducing the time interval between periodic inspections and increasing the number of replaced components at each stage of the inspection can keep the system reliability as expected.

A new recognition moiety diphenylborinate in the detection of pyruvate via Lewis acid/base sensing pathway and its bioimaging applications

Developing new reaction based recognizing units can enhance the specificity of target analyte molecules in practical applications of real samples and biosystems. Therefore, introducing a recognizing moiety diphenylborinate was encountered for the detection of pyruvate biomolecule through Lewis acid-base reaction based sensing strategy. The construction of the Schiff-base back bone between quinoline and N-(diethylamino)salicylaldehyde-diphenylborinate (QSB) were expressed the red shift from blue emission of quinoline in to green as that of dative bond developed between Schiff base nitrogen and boron atoms. The new sensing approach was involved such a way that fluorophore QSB is a Lewis acid while pyruvate acts as Lewis base, where the elimination of Lewis pair produced a weak green fluorescence including the formation of quinoline, N-(diethylamino)salicylaldehyde (QS). The switching products were witnessed through 1H NMR titration, HR-MS and FT-IR studies. The good selectivity and interference ability were achieved in presence of 1000-fold excess of possible interferences with LOD of 16 nM. Moreover, the tracking ability of the probe was employed towards pyruvate in live HeLa cell imaging for evaluating an exogenous and endogenous signals producing ability and its mitochondria targeting property was investigated successfully. Further, the practical utility of the probe was tested with milk samples and obtained good recovery results.

Rationally designed modular drug delivery platform based on intracellular peptide self-assembly.

Modulated molecular design-based intracellular self-assembly strategy has showed great potentiality in drug delivery, due to its assembling nature-resulted optimized drug biodistribution and metabolism. The modular designing concept endows the delivery system multiple functions, such as, selectivity and universality to improve the pharmacokinetics of loaded drugs. However, the accurate controlling of the self-assembling process in desired site to achieve optimal drug delivery is posed great challenges toward rational molecular design. Here, we fabricated a modulated drug-delivery system (MDS) through intracellular peptide self-assembly to realize effective drug delivery. MDS was designed based on modulated molecular designing strategy which contains five functional motifs and effectively transformed into fibrous nanostructures inside target cells by caspase3/7 hydrolysis directed in situ self-assembly. The experimental studies and molecular simulations were carried out to evaluate the successful construction and delivering efficacy of MDS. According to the experimental results and molecular simulation analysis, the percentage of solvent-exposed surface area of assembling modular (KLVFFAE), as well as its non-covalent interaction between four other modules synergeticly decide the solubility of molecules. The weak intramolecular forces of the peptide back bone, such as, hydrogen bond, as well as multivalent interactions of the side chains such as, salt bridge and hydrophobic interaction both contribute to the self-assembly of the molecules. The significant structural difference between delivering molecules optimize the system to adapt hydrophilic and hydrophobic drugs. Finally, the predicted drug delivery molecule specifically recognizes targeted cancer cell lines and self-assembles to form fibers intracellularly, resulting in prolonged drug retention and accumulation. The regular prediction and rational molecular design will benefit the further construction and optimization of modulated drug delivery platform.

The European Medicines Agency Review of Luspatercept for the Treatment of Adult Patients With Transfusion-dependent Anemia Caused by Low-risk Myelodysplastic Syndromes With Ring Sideroblasts or Beta-thalassemia.

Luspatercept is a recombinant fusion protein that selectively binds to ligands belonging to the transforming growth factor-beta superfamily, resulting in erythroid maturation and differentiation. On June 25, 2020, a marketing authorization valid through the European Union (EU) was issued for luspatercept for the treatment of adult patients with transfusion-dependent anemia caused by very low-, low-, and intermediate-risk myelodysplastic syndromes (MDS) with ring sideroblasts, or those with transfusion-dependent beta thalassemia (BT). Luspatercept was evaluated in 2 separate phase 3, double-blind, placebo-controlled multicentre trials. The primary endpoints of these trials were the percentage of patients achieving transfusion independence over ≥8 weeks or longer for patients with MDS, and the percentage of patients achieving a ≥33% reduction in transfusion burden from baseline to week 13–24 for patients with BT. In the MDS trial, the percentage of responders was 37.91% versus 13.16%, P < 0.0001, for patients receiving luspatercept versus placebo, respectively. In the BT trial, the percentage of responders was 21.4% versus 4.5% (P < 0.0001) for luspatercept versus placebo, respectively. Treatment with luspatercept led to similar incidences of adverse events (AEs), but higher incidences of grade ≥3 AEs and serious AEs compared to placebo. The most frequently reported treatment-emergent AEs (≥15%) in the pooled luspatercept group were headache; back pain, bone pain, and arthralgia; diarrhea; fatigue; pyrexia; and cough. The aim of this article is to summarize the scientific review of the application, which led to the regulatory approval in the EU.

Demand Side Management Techniques for Peak Reduction

Industrial growth is the back bone for the development of any nation. Industries are mainly dependent on electrical energy. But from the various studies, the sources for electrical energy are decreasing gradually, and in turn, the gap is increasing between the supplier and the load. The solution for this scenario is optimal utilization of resources. To overcome this problem , the concept Demand Side Management (DSM) has emerged in Power System Planning and Management. The principle objective of DSM is mutual understanding between the supplier and the consumer for maximizing benefits and minimizing inconvenience. The aim of this research work is selection and application of appropriate DSM techniques to industrial and domestic loads for peak load management and energy conservation, that is to control the maximum demand during the peak hours and saving the energy by using the energy efficient and intelligent appliances like air conditioners and water heaters. DSM includes techniques like the End Use Equipment Control, the Load Priority Technique, he Peak Clipping &amp; Valley filling, the Differential Tariff and Resizing of the equipment. Depending upon the application, all the techniques may be applied sequentially, or only a few of them can be applied. There is a lot of ambiguity in the selection of DSM techniques, because the application of each DSM technique depends on the case study and the problem associated with the respective case study. After comprehensive understanding of a particular case, a thorough investigation and subsequent data analysis pave the way for the selection of appropriate DSM technique/techniques

Sacrum magnetic resonance imaging for low back and tail bone pain: A quality initiative to evaluate and improve imaging utility.

As quality and cost effectiveness become essential in clinical practice, an evidence-based evaluation of the utility of imaging orders becomes an important consideration for radiology’s value in patient care. We report an institutional quality improvement project including a retrospective review of utility of sacrum magnetic resonance (MR) imaging for low back pain at our institution over a four-year period and follow-up results after physician education intervention. Sacral MR imaging for low back pain and tailbone pain were only positive for major findings in 2/98 (2%) cases, and no major changes in patient management related to imaging findings occurred over this period, resulting in almost $500000 cost without significant patient benefit. We distributed these results to the Family Medicine department and clinics that frequently placed this order. An approximately 83% drop in ordering rate occurred over the ensuing 3 mo follow-up period. Sacrum MR imaging for low back pain and tail bone pain has not been a cost-effective diagnostic tool at our institution. Physician education was a useful tool in reducing overutilization of this study, with a remarkable drop in such studies after sharing these findings with primary care physicians at the institution. In conclusion, sacrum MR imaging rarely elucidates the cause of low back/tail pain diagnosed in a primary care setting and is even less likely to result in major changes in management. The practice can be adopted in other institutions for the benefit of their patients and improve cost efficiency.

Phylosophy of constitushional law

Constitushional law is a legal system that is a world of extraordinary thoughts it is back bone of the highest legal doctrines.

Efficient parallelization of SPH algorithm on modern multi-core CPUs and massively parallel GPUs

Smoothed Particle Hydrodynamics (SPH) is fast emerging as a practically useful computational simulation tool for a wide variety of engineering problems. SPH is also gaining popularity as the back bone for fast and realistic animations in graphics and video games. The Lagrangian and mesh-free nature of the method facilitates fast and accurate simulation of material deformation, interface capture, etc. Typically, particle-based methods would necessitate particle search and locate algorithms to be implemented efficiently, as continuous creation of neighbor particle lists is a computationally expensive step. Hence, it is advantageous to implement SPH, on modern multi-core platforms with the help of High-Performance Computing (HPC) tools. In this work, the computational performance of an SPH algorithm is assessed on multi-core Central Processing Unit (CPU) as well as massively parallel General Purpose Graphical Processing Units (GP-GPU). Parallelizing SPH faces several challenges such as, scalability of the neighbor search process, force calculations, minimizing thread divergence, achieving coalesced memory access patterns, balancing workload, ensuring optimum use of computational resources, etc. While addressing some of these challenges, detailed analysis of performance metrics such as speedup, global load efficiency, global store efficiency, warp execution efficiency, occupancy, etc. is evaluated. The OpenMP and Compute Unified Device Architecture[Formula: see text] parallel programming models have been used for parallel computing on Intel Xeon[Formula: see text] E5-[Formula: see text] multi-core CPU and NVIDIA Quadro M[Formula: see text] and NVIDIA Tesla p[Formula: see text] massively parallel GPU architectures. Standard benchmark problems from the Computational Fluid Dynamics (CFD) literature are chosen for the validation. The key concern of how to identify a suitable architecture for mesh-less methods which essentially require heavy workload of neighbor search and evaluation of local force fields from neighbor interactions is addressed.

“Mucormycosis” the Emerging Global Threat; Overview and Treatment Outcome Among Pediatric Cancer Patients in Egypt

Background: Mucormycosis is a serious emerging fungal infection. Unlike invasive aspergillosis, the prognosis and outcome of hematologic malignancy patients who develop invasive Mucormycosis have not significantly improved over the past decade.The aim of the study was to evaluate clinical characteristics and treatment outcome in pediatric oncology patients with Mucormycosis in children cancer hospital 57357, Cairo, Egypt. Patients and Methods: A retrospective study during the period from 2007 to 2016. Data collected included patients' demographics, diagnosis, risk factors, diagnostic work up, antifungal treatment given and treatment outcome. Diagnosis was made according to the EORTC/MSG modified criteria (2008). Results: During the study period, 45 patients developed proven Mucormycosis. Mean age was 8 years (range 2-17). Male to female ratio 1:1. Diagnosis of Mucormycosis was highest among patients with hematological malignancies (90%). Twenty-two cases of acute myeloid leukemia (49%), 17 cases acute lymphoblastic leukemia (37%), and 1 case of CML post-transplant. The other 10% were having solid malignancies. Sinus involvement has been documented in (55.5%) representing the sole localization in 16 cases. The other 9 patients had secondary localizations; 2 central nervous system (Rhino-cerebral) and 7 lung (Sino-pulmonary) cases. Other primary sites of infection were: Pulmonary, Cutaneous and Gastrointestinal in (13.3%), (8.8%) and (11%) respectively. Disseminated disease was seen in 5 cases (11%). All patients had infection documented by histopathology or/and culture. Diagnosis was reported by histopathology in 38 patients (84%), blood culture in 2 patients (4 %) and both culture and histopathology in 5 patients (12%). At time of diagnosis, 15 patients (33%) were on Voriconazole prophylaxis (n =13) or Micafungin (n= 2). Liposomal Amphotercin -B 5mg/kg/day was the mainstay of treatment with duration ranging from 3 to 4 weeks. Posaconazole was used as secondary prophylaxis in 35 % of cases mainly for patients with hematological malignancies. Combination of liposomal amphotericin B with caspofungin was used in 3 cases with progressive Mucormycosis. Surgical intervention was achievable in 50 % of cases; sinus debridement in 11 cases, lung lobectomy in 3 cases, intestinal resection anastomosis in 5 cases and debridement of necrotic lesion in 4 cases. Therapy was successful in 30 patients (66%). Co-Morbidities related to Mucormycosis was seen in 5 cases with disfigurement, and perforated hard palate. Chemotherapy delay with subsequent relapse of primary malignancy was reported in 1 case. Mucormycosis was the primary cause of death in 15 cases (34%). Gastrointestinal and disseminated Mucormycosis was independent risk factors for mortality. Conclusion: Early diagnosis of Mucormycosis infection, with rapid initiation of appropriate antifungal therapy and surgical intervention, whenever feasible, are the back bone of decreasing Mucormycosis-related mortality and morbidity among pediatric cancer patients. Disseminated and gastrointestinal Mucormycosis had higher risk for mortality. DisclosuresNo relevant conflicts of interest to declare.