Applications Of Electrospun Nanofibers Research Articles

The Applications of Electrospun Nanofibers in the Medical Materials

Electrospinning is a novel processing technique for the production of nanofiber non-woven materials and nanofiber non-woven materials have extremely high surface-to-mass (or volume) ratio and a porous structure .for the advantages of electrospun nanofiber non-woven materials, it can be used many filed. This review introduction the progress of electrospun nanofibers and summarize the application of electro spun nanofibers in the medical materials filed.

Development of braided drug-loaded nanofiber sutures

The objectives of this work are twofold. Firstly, while most work on electrospinning islimited to the development of only functional materials, a structural application ofelectrospun nanofibers is explored. Secondly, a drug-loaded tissue suture is fabricated andits various properties are characterized. Braided drug-loaded nanofiber sutures are obtainedby combining an electrospinning process with a braiding technique followed by a coatingprocedure. Two different electrospinning techniques, i.e. blend and coaxial electrospinning,to incorporate a model drug cefotaxime sodium (CFX-Na) into poly(L-lactic acid) (PLLA)nanofibers have been applied and compared with each other. Properties of the braideddrug-loaded sutures are characterized through a variety of methods including SEM,TEM and tensile testing. The results show that the nanofibers had a preferablemicromorphology. The drug was incorporated into the polymer nanofibers homogeneously,with no cross-linking. The nanofibers maintained their fibrous structures. Anin vitro release study indicates that the drug-loaded nanofibers fabricated byblend electrospinning and coaxial electrospinning had a different drug releasebehavior. An inhibition zone experiment shows that both sutures obtained from thenanofibers of the different electrospinning techniques had favorable antibacterialproperties. The drug-loaded sutures had preferable histological compatibilityperformance compared with commercial silk sutures in an in vivo comparative study.

Some fascinating phenomena in electrospinning processes and applications of electrospun nanofibers

AbstractElectrospinning has the unique ability to produce ultrathin fibers from a rich variety of materials that include polymers, inorganic or organic compounds and blends. With the enormous increase of research interest in electrospun nanofibers, there is a strong need for a comprehensive review of electrospinning in a systematic fashion. This article presents some fascinating phenomena associated with the remarkable features of nanofibers in electrospinning processes and new progress in applications of electrospun nanofibers. Copyright © 2007 Society of Chemical Industry