Modifying pea protein via dynamic high-pressure microfluidization and polyphenol/polysaccharide incorporation to stabilize high internal phase Pickering emulsions for 3D printing.

Broccoli leaves, despite their rich bioactive content, are considered non-edible, thus wasted. High-pressure homogenization (HPH) is a non-thermal, water-based technique that is emerging as an alternative for processing agri-food waste. In this study, the effects of HPH (performed at 90MPa) on the physicochemical and phytochemical properties of broccoli leaves were evaluated and compared to a conventional blending method. HPH-treated samples exhibited smaller, greener particles with evident cell disruption. In the serum, broccoli leaves treated with HPH showed higher concentrations of amino acids and monosaccharides. Additionally, methanolic extracts of HPH-treated samples presented greater contents of total phenolics, flavonoids, and glucosinolates, as confirmed by metabolomic analysis. A total of 201 compounds were annotated, with 22 uniquely detected in HPH-treated samples and 16 in blended ones. HPH-treated extracts also exhibited higher antioxidant activity, more than doubling the activity at all concentration ranges studied. Altogether, these findings indicate that HPH improves the physicochemical properties, bioactive compound extraction, and antioxidant capacity of broccoli leaves.

Anti-oxidant, anti-estrogenic and anti-inflammatory activities of the UHPLC fingerprinted Acacia seyal Delile (Mimosaceae) extracts: possible anticancer modes of action.

Hepatoprotective effects of tetrahydropalmatine against NAFLD through autophagy activation and lipid metabolic reprogramming via the AMPK-mTOR-Sirt1 axis.

Heat-induced regulation on metabolite biosynthesis improves antioxidant capacity and nutritional quality of black highland barley (Hordeum vulgare L.).

Cannabis sativa L. has a long history of traditional use for the treatment of pain and inflammatory disorders in both Asian and European medical systems, which supports its investigation as a source of bioactive compounds with potential relevance for chronic immune-mediated diseases. This study evaluated the ten major non-psychotropic phytocannabinoids for their anti-inflammatory and antioxidant activities, and for synergistic interactions with non-cannabinoid matrices derived from the same plant (polar, non-polar and terpenoid). Anti-inflammatory effects were assessed in macrophage-differentiated THP-1cells by measuring pro-inflammatory cytokine production (ELISA) and nuclear factor kappa B (NF-κB) pathway activation (luciferase reporter assay). All tested phytocannabinoids demonstrated anti-inflammatory effects, in particular, cannabidivarin (CBDV) reduced IL-6, TNF-α production and also inhibited NF-κB activation. Several phytocannabinoids, especially their acidic forms, exhibited high oxygen radical absorption capacity (ORAC), but none showed significant cellular antioxidant activity (CAA), possibly due to limited bioavailability. Importantly, several phytocannabinoid-matrix mixtures displayed synergistic anti-inflammatory effects, with combinations containing cannabigerol (CBG) or cannabinol (CBN) being particularly potent. These findings highlight the potential of lesser-known phytocannabinoids, especially in combination with specific C. sativa L. matrix components, to modulate inflammatory pathway supporting their development as functional ingredients for managing chronic gut-associated inflammation.

Is oxidative stress in the brain correlated with plasma markers of oxidative stress?

Dietary supplementation with Enterococcus faecium Ef026 elicits a systemic improvement in Hy-Line Brown laying hens during the mid-to-late laying phase.

Effects of drinking water temperature in summer on growth performance, water consumption, surface temperature, blood parameters, and intestinal development of geese from 14 to 42 days of age.

Rosemary extract mitigates deoxynivalenol-induced intestinal inflammation in weaned piglets via activation of the Nrf2/HO-1 pathway and suppression of NF-κB/MAPK signaling.

Analysis of paraoxonase-1 activity and cupric reducing antioxidant capacity in cerebrospinal fluid of dogs with neurological disorders.

Supplementation of Angelica sinensis improves the growth performance, hepatic antioxidant function, and composition of intestinal microbiota in Tan sheep.

Effects of dietary Phellinus linteus polysaccharides supplementation on productive performance, egg quality, antioxidant status, immune function, cecal microbiota, jejunal morphology, and metabolism in laying hens under lipopolysaccharide challenge.

Phenolic extracts are recognized for their health-promoting properties, although some physicochemical characteristics limit their food applications. The present study aimed to valorize orange juice by-products through enzymatic and hydroalcoholic extraction to obtain flavonoid ingredients and to evaluate their application in pectin-based jelly candies as a functional delivery system. Hydroalcoholic extraction yielded higher total phenolic content and antioxidant capacity, with flavonoids, particularly hesperidin, as the predominant compound. Enzymatic extraction favored the recovery of aglycone forms, especially hesperetin. The incorporation of both extracts (0.1 and 0.2 g kg-1) into jelly candies preserved key techno-functional properties, including moisture (15.34-16.91%) and water activity (0.7285-0.7375), with extract-specific effects on texture (hardness, adhesiveness and stickiness) and color attributes. HPLC analysis confirmed the successful incorporation of characteristic flavonoids into the candy matrix. Despite differences in phenolic content among extracts, the extract type did not significantly affect phenolic bioaccessibility after in vitro simulated digestion. All formulations exhibited controlled release and high phenolic bioaccessibility (> 90%), indicating effective protection and delivery of bioactive compounds within the pectin matrix. Orange by-products can be upcycled into flavonoid extracts suitable for incorporation into pectin-based jelly candies without compromising technological quality. The high phenolic bioaccessibility highlights the potential of these candies as functional confectionery products. It supports the use of pectin gels as effective bioactive delivery systems within a circular economy framework. © 2026 The Author(s). Journal of the Science of Food and Agriculture published by John Wiley & Sons Ltd on behalf of Society of Chemical Industry.

Research on the ultrasonic-assisted extraction, purification, structural characterization, and anti- glycolipid metabolic disorder (anti-GLMD) activity and mechanism of polysaccharide from Dryopteridis crassirhizomatis Rhizoma.

Anticancer mechanisms of Poikilospermum suaveolens root fraction: ethnopharmacological relevance, signaling pathways, and in vitro/in silico studies on MCF-7 cells.

Comparative analysis of sensory properties, chemical composition, and antioxidant activity in aqueous extracts from medicinal and edible citrus resources: Electronic tongue, UPLC-Q-TOF-MS/MS, antioxidant capacity, and molecular docking.

Effects of lysine supplementation in fishmeal-free feeds on growth performance, protein metabolism, and antioxidant capacity in Procambarus clarkii

Enhancing tilapia robustness: Moringa essential oil improves growth, gut morphology, innate immunity, antioxidant capacity, and ammonia tolerance in Nile tilapia

Effects of dietary microalgae supplementation at different levels on Macrobrachium rosenbergii insect meal-based diets: Antioxidant capacity, hepatopancreatic morphology, and carotenoid retention