Affective Subscale Research Articles

The Relationship between Diabetes-Related Factors, Family Functioning and Health-Related Quality of Life in Turkish Adolescents with Type 1 Diabetes Mellitus

ABSTRACTThis cross-sectional, convenience sampling study examined the relationship between diabetes-related factors, family functioning, and health-related quality of life (HRQOL) in 100 Turkish adolescents with type 1 diabetes mellitus (T1DM). The mean adolescent age was 14.65 ± 1.13 years. Quality of life was assessed using the Kiddo-KINDL generic HRQOL scale. Family functioning was assessed using the McMaster Family Assessment Device. The findings revealed that the participants had moderately high HRQOL. In terms of family functioning, general family functions subscale appeared healthy whereas affective involvement subscale appeared unhealthy. Results revealed that HbA1c was significantly negatively correlated with HRQOL. The full model of the socio-demographic, diabetes-related variables and general family functions to predict the total quality of life in children with T1DM was statistically significant. The overall multivariate model accounted for 58% of the variance of the total HRQOL. Regression analyses revealed that the levels of HbA1c and family functioning were significantly negatively related with HRQOL. The relationships between family functioning and HRQOL in adolescents with T1DM were unclear in Turkish sample. This research addressed this gap of knowledge, and provided a greater insight for practitioners working with adolescents with T1DM.

Preliminary findings for the validity of the Morningness–Eveningness-Stability Scale improved (MESSi): Correlations with activity levels and personality

ABSTRACTAim of the present study is an additional validation of the Morningness–Eveningness-Stability Scale improved (MESSi). We screened a total of 97 German students using the reduced Morningness–Eveningness Questionnaire (rMEQ) to identify a subsample (N = 42) of definite morning and evening types (31% males, mean age: 24.8 ± 5.8 years). The participants provided information about their sleep–wake rhythm (diary), personality traits (questionnaire) and experienced actigraphic monitoring. Correlations of the MESSi components “Morning affect subscale” (MA) (r = 0.91, p < 0.01) and “Eveningness subscale” (r = −0.87, p < 0.01) with the rMEQ showed good convergent validity. MA was also significantly negatively correlated with the acrophase and the midpoint of sleep as measured by actigraphy.

Comparing the effect of eye movement desensitization and reprocessing (EMDR) with guided imagery on pain severity in patients with rheumatoid arthritis

ObjectivePrevious studies reported the reduction of pain following eye movement desensitization and reprocessing (EMDR) and guided imagery; however, the effectiveness of these modalities was not compared. The current study aimed to compare the effects of EMDR and guided imagery on pain severity in patients with rheumatoid arthritis.Material and methodsIn this randomized controlled trial, 75 patients were selected using non-random method, and then allocated into two intervention groups and one control group. Interventions were conducted individually in six consecutive sessions for the intervention groups. The Rheumatoid Arthritis Pain Scale was used for data collection before and after the interventions. Collected data were analyzed with descriptive and inferential statistics in SPSS. Significance level was considered at P<0.05.ResultsThe post-intervention mean scores of physiological, affective, sensory-discriminative, and cognitive pain sub-scales for patients in guided imagery group were 16.3±2.2, 13.9±2.2, 30.6±3.4, and 23.2±3, respectively. The post-intervention mean scores of these sub-scales in the EMDR group were 22±1.5, 18.1±1.8, 39.6±2.8, and 29±1.8, respectively. A significant difference was observed in the mean pain score between EMDR and guided imagery groups, and also between each intervention group and the control group (P=0.001).ConclusionGuided imagery and EMDR could reduce pain in rheumatoid arthritis, but pain reduction was more following the EMDR than guided imagery.

Cognitive and Affective Benefits of a Mindful State in Response to and in Anticipation of Pain

The present study aimed to extend the existing literature of mindfulness as a stress protective factor by (1) exploring the role of mindfulness state, not only in response to but also in anticipation of acute pain and (2) investigating an explanatory pathway, decreased rumination, between anticipation of acute pain and cognitive performance, with mindfulness moderating this indirect effect. One-hundred-and-four undergraduates were assessed for state mindfulness and then underwent an acute pain induction using the cold pressor task (CPT). Pain measures included pain threshold, pain tolerance, pain intensity, short-form McGill Pain questionnaire, and pain catastrophizing. Next, half of the participants were told that they would be repeating the CPT after some intervening tasks; half were not told to expect a second CPT. Participants completed a Cognitive Estimation Task (CET) that involved problem-solving, followed by a measure of rumination during CET. Results showed no meaningful associations between mindfulness state and sensory measures of pain (e.g., pain tolerance, pain threshold), but higher mindfulness state was related to lower pain catastrophizing and lower McGill affective subscale scores. There was also evidence of a moderated indirect effect: the indirect effect of condition through rumination on CET performance was moderated by mindfulness. That is, those in the anticipation condition with higher mindfulness state later reported ruminating less during CET and performed better at CET. Mindfulness thus appeared to have a protective role in maladaptive emotional responses when one anticipates acute pain, shielding self-regulatory resources needed to think flexibly when expecting a stressor.

Type D Personality as a Predictor of Resilience Among Nursing Students

Understanding the factors that influence resilience is especially important in the context of emotionally demanding work environments in health care. The aim of this study is to examine the associations between Type D personality and resilience among nursing students. A correlational study design was used, and 150 baccalaureate nursing students participated. The Type D personality subscale, sense of coherence questionnaire, and Baruth protective factors inventory were used. Linear regression analysis and Student's t tests were used. The negative affectivity subscale of the Type D scale was a significant predictor for resilience and sense of coherence. Students with high levels of Type D characteristics had significantly lower levels of resilience and sense of coherence. It would be beneficial to include specific interventions for decreasing negative affectivity and promoting stress coping skills training in the training programs in nursing school curricula. [J Nurs Educ. 2018;57(5):296-299.].

Sleep disturbances and their associations with emotional/behavioural problems in 5-year-old boys with autism spectrum disorders

ABSTRACTSleep disturbances are likely to be associated with emotional and behavioural problems in typically and atypically developing children. The study was aimed to evaluate sleep disturbances in children with autism spectrum disorder (ASD) and their associations with emotional/behavioural problems. The study comprised eighteen 5-year-old boys with diagnosed ASD. Control group was made up of matched 54 clinically healthy typically developing boys. The mothers were requested to fill in Child Sleep Habit Questionnaire (CSHQ) aimed to measure certain sleep troubles in children and the Achenbach Child Behaviour Check List (CBCL/1.5–5) aimed to find major emotional/behavioural disturbances. Children with ASD had significantly higher scores on sleep onset delay, night waking, parasomnia, sleep disordered breathing and daytime sleepiness scores. They also presented with statistically significantly higher values on affective, anxiety, pervasive developmental, attention deficit/hyperactivity and oppositional defiant problems subscales. Predictive analysis showed that anxiety problems could be finely predicted by ASD diagnosis, low IQ, sleep delay, sleep anxiety, and daytime sleepines. Affective problems could be predicted by ASD diagnosis, night waking and low IQ. So far as attention deficit/hyperactivity and oppositional defiant problems were concerned, these variables were most dependant on child IQ and gastrointestinal symptoms. Sleep disturbances in children with ASD are common and may be associated with emotional problems.

Affective and cognitive rather than somatic symptoms of depression predict 3-year mortality in patients on chronic hemodialysis

Depression is more common in many medical conditions than among the general population and is associated with an increased risk of mortality. We aimed to determine whether somatic symptoms of depression were more predictive of mortality than affective and cognitive symptoms in hemodialysis patients. We conducted a prospective cohort study in which the survival outcomes of 151 subjects were followed for more than 3 years. Depression was assessed with the Taiwanese Depression Questionnaire (TDQ). Subjects with TDQ scores 19–54 (correlated with clinically significant depressive symptoms) and those with scores 15–18 had higher 3-year mortality rates than the two groups with lower scores (40.0%, 46.7%, 16.0% and 19.6%, p = 0.021, ANOVA). Affective and cognitive symptoms, including sadness, tenseness, indecisiveness and low self-confidence, and one somatic item (bodily discomfort) were associated with mortality. Affective and cognitive symptoms affected quality of life more than somatic symptoms. The somatic subscale was associated with female gender, low income and education, dialysis vintage, and low serum creatinine and albumin levels, whereas the affective and cognitive subscale was associated with less education and a low serum albumin level. In conclusion, affective and cognitive symptoms of depression may better predict long-term mortality in patients undergoing chronic hemodialysis than somatic symptoms.

F186. TAPETUM ABNORMALITIES IN FIRST-EPISODE PSYCHOSIS AND RELATIONSHIP TO SYMPTOM SEVERITY AND DURATION OF UNTREATED PSYCHOSIS

BackgroundDiffusion tensor imaging (DTI) studies have shown white-matter (WM) abnormalities in most corpus callosum segments in first-episode psychosis (FEP) patients. However, the tapetum, one of its sub-segments, is not fully studied until now. This study focuses on tapetum and its relationship with psychotic disorders using DTI with symptom severities and duration of untreated psychosis (DUP).MethodsNinety-five FEP patients and thirty healthy controls (HCs) were enrolled. Tapetum, region of interest was extracted using 3D slicer and tract-based spatial statistics (TBSS) were used for DTI analysis. All patients were assessed DUP and clinical symptoms by Scale for the Assessment of Positive Symptoms (SAPS), Scale for the Assessment of Negative Symptoms (SANS) at baseline.ResultsTBSS revealed that fractional anisotropy (FA) values of tapetum in FEP is significantly decreased compared to HCs (p<0.01, FWE-corrected). Exploratory correlational analysis revealed significant negative correlations between FA values of left tapetum and baseline SAPS total scores (r =-0.278, p<0.05), bizarre behavior subscale scores (r =-0.310, p<0.01), positive formal thought disorder subscale scores (r =-0.348, p<0.01), inappropriate affect subscale scores (r =-0.315, p<0.01) and SANS avolition-apathy subscale scores (r =-0.257, p<0.05). Also FA values of left tapetum was negatively correlated with DUP (r =-0.426, p<0.00).DiscussionFEP patients show a significant reduction in WM integrity of left tapetum, also show correlation with clinical symptoms and DUP. These results suggested that left tapetum may play a role in symptom severities and prognosis in FEP.

A pragmatic randomised controlled trial and economic evaluation of family therapy versus treatment as usual for young people seen after second or subsequent episodes of self-harm: the Self-Harm Intervention - Family Therapy (SHIFT) trial.

Self-harm in adolescents is common and repetition rates high. There is limited evidence of the effectiveness of interventions to reduce self-harm. To assess the clinical effectiveness and cost-effectiveness of family therapy (FT) compared with treatment as usual (TAU). A pragmatic, multicentre, individually randomised controlled trial of FT compared with TAU. Participants and therapists were aware of treatment allocation; researchers were blind to allocation. Child and Adolescent Mental Health Services (CAMHS) across three English regions. Young people aged 11-17 years who had self-harmed at least twice presenting to CAMHS following self-harm. Eight hundred and thirty-two participants were randomised to manualised FT delivered by trained and supervised family therapists (n = 415) or to usual care offered by local CAMHS following self-harm (n = 417). Rates of repetition of self-harm leading to hospital attendance 18 months after randomisation. Out of 832 young people, 212 (26.6%) experienced a primary outcome event: 118 out of 415 (28.4%) randomised to FT and 103 out of 417 (24.7%) randomised to TAU. There was no evidence of a statistically significant difference in repetition rates between groups (the hazard ratio for FT compared with TAU was 1.14, 95% confidence interval 0.87 to 1.49; p = 0.3349). FT was not found to be cost-effective when compared with TAU in the base case and most sensitivity analyses. FT was dominated (less effective and more expensive) in the complete case. However, when young people's and caregivers' quality-adjusted life-year gains were combined, FT incurred higher costs and resulted in better health outcomes than TAU within the National Institute for Health and Care Excellence cost-effectiveness range. Significant interactions with treatment, indicating moderation, were detected for the unemotional subscale on the young person-reported Inventory of Callous-Unemotional Traits (p = 0.0104) and the affective involvement subscale on the caregiver-reported McMaster Family Assessment Device (p = 0.0338). Caregivers and young people in the FT arm reported a range of significantly better outcomes on the Strengths and Difficulties Questionnaire. Self-reported suicidal ideation was significantly lower in the FT arm at 12 months but the same in both groups at 18 months. No significant unexpected adverse events or side effects were reported, with similar rates of expected adverse events across trial arms. For adolescents referred to CAMHS after self-harm, who have self-harmed at least once before, FT confers no benefits over TAU in reducing self-harm repetition rates. There is some evidence to support the effectiveness of FT in reducing self-harm when caregivers reported poor family functioning. When the young person themselves reported difficulty expressing emotion, FT did not seem as effective as TAU. There was no evidence that FT is cost-effective when only the health benefits to participants were considered but there was a suggestion that FT may be cost-effective if health benefits to caregivers are taken into account. FT had a significant, positive impact on general emotional and behavioural problems at 12 and 18 months. There was significant loss to follow-up for secondary outcomes and health economic analyses; the primary outcome misses those who do not attend hospital following self-harm; and the numbers receiving formal FT in the TAU arm were higher than expected. Evaluation of interventions targeted at subgroups of those who self-harm, longer-term follow-up and methods for evaluating health benefits for family groups rather than for individuals. Current Controlled Trials ISRCTN59793150. This project was funded by the NIHR Health Technology Assessment programme and will be published in full in Health Technology Assessment; Vol. 22, No. 12. See the NIHR Journals Library website for further project information.

Affect and Incident Participation Restriction in Adults With Knee Osteoarthritis.

Participation restriction, common among people with knee osteoarthritis (OA), may be influenced by affect. We examined the risk of incident participation restriction over 84 months conferred by positive and negative affect among people with knee OA. Participants were from the Multicenter Osteoarthritis Study and had or were at high risk of knee OA. Participation restriction was measured using the Instrumental Role Limitation subscale of the Late-Life Disability Index, and affect was measured using the positive affect and depressed mood subscales of the Center for Epidemiologic Studies Depression Scale. Robust Poisson regression was used to calculate the risk of incident participation restriction over 84 months conferred by combinations of low and high positive and negative affect, adjusting for covariates. Of 1,810 baseline participants (mean age 62.1 years, 56% female), 470 (26%) had incident participation restriction over 84 months. Participants with low positive affect had 20% greater risk of incident participation restriction than those with high positive affect; participants with high negative affect had 50% greater risk of incident participation restriction compared to those with low negative affect. Participants with both low positive and high negative affect had 80% greater risk of incident participation restriction compared to other combinations of positive and negative affect. Low positive and high negative affect, both alone and in combination, increase the risk of participation restriction among adults with knee OA. Efforts aimed at preventing participation restriction in this population should consider these mood states.

Associations between subclinical depressive symptoms and reduced brain volume in middle-aged to older adults

ABSTRACTObjectives: The associations between subclinical depressive symptoms, as well specific symptom subscales, on brain structure in aging are not completely elucidated. This study investigated the extent to which depressive symptoms were related to brain volumes in fronto-limbic structures in a sample of middle-aged to older adults.Method: Eighty participants underwent structural neuroimaging and completed the Beck Depression Inventory, 2nd Edition (BDI-II), which comprises separate affective, cognitive, and somatic subscales. Gray matter volumes were extracted from the caudal and rostral anterior cingulate, posterior cingulate, hippocampus, and amygdala. Hierarchical regression models examined the relationship between brain volumes and (i) total depressive symptoms and (ii) BDI-II subscales were conducted.Results: After adjusting for total intracranial volume, race, and age, higher total depressive symptoms were associated with smaller hippocampal volume (p = 0.005). For the symptom subscales, after controlling for the abovementioned covariates and the influence of the other symptom subscales, more somatic symptoms were related to smaller posterior cingulate (p = 0.025) and hippocampal (p < 0.001) volumes. In contrast, the affective and cognitive subscales were not associated with brain volumes in any regions of interest.Conclusion: Our data showed that greater symptomatology was associated with smaller volume in limbic brain regions. These findings provide evidence for preclinical biological markers of major depression and specifically advance knowledge of the relationship between subclinical depressive symptoms and brain volume. Importantly, we observed variations by specific depressive symptom subscales, suggesting a symptom-differential relationship between subclinical depression and brain volume alterations in middle-aged and older individuals.

Hubungan antara Status Mood dan Fungsi Kognitif dalam Kalangan Warga Emas yang Mempunyai Kecelaan Kognitif Ringan

There is some evidence stated that mood states might influence cognitive functioning, such as episodic memory, working memory and creative problem solving. This study was conducted to evaluate the relationship between mood states and cognitive functioning among older adults with Mild Cognitive Impairment (MCI). This study involved 12 male and 37 female subjects from Klang Valley aged 60 year old and above. MCI was defined based on criteria proposed by Peterson. Cognitive functions of the subjects were accessed using Mini Mental State Examination (MMSE), Rey Auditory Verbal Learning Test (RAVLT), Digit Span, Digit Symbol Substituition Test (DSST) and Visual Reproduction; while mood states including tension, depression, anger, vigour, esteem related affect, fatigue and confusion were accessed using Profile of Mood States (POMS) questionnaire. Total positive subscales score, total negative subscales score and total mood disturbance (TMD) were also calculated. There were significant positive correlations between tension (r = 0.325, p = 0.30), vigour (r = 0.235, p = 0.036), esteem related affect (r = 0.316, p = 0.034) and total positive subscales score (r = 0.307, p = 0.040) with verbal episodic memory as measured using RAVLT fifth trial. In addition, positive correlations were also observed between vigour (r = 0.228, p = 0.035) and total positive subscales score (r = 0.237, p = 0.025) with DSST. After adjusted for confounding factors, subjects who scored higher in esteem related affect (Adjusted OR = 0.390, 95% CI [0.069-0.711], p = 0.019) and tension (Adjusted OR = 0.253, 95% CI [0.075-0.431], p = 0.007) had better verbal episodic memory. Subjects who have higher total positive subscales score were also had faster processing speed (OR = 0.856, 95% CI [0.099-1.614], p = 0.028). However after adjusted for confounding factors, the relationship was not significant (Adjusted OR = 0.383, 95% CI [-0.247-1.013], p = 2.226). Older adults with MCI who had a more positive mood tend to have a better short-term verbal memory and faster processing speed. DOI : http://dx.doi.org./10.17576/JSKM-2018-42

Hubungan antara Status Mood dan Fungsi Kognitif dalam Kalangan Warga Emas yang Mempunyai Kecelaan Kognitif Ringan

There is some evidence stated that mood states might influence cognitive functioning, such as episodic memory, working memory and creative problem solving. This study was conducted to evaluate the relationship between mood states and cognitive functioning among older adults with Mild Cognitive Impairment (MCI). This study involved 12 male and 37 female subjects from Klang Valley aged 60 year old and above. MCI was defined based on criteria proposed by Peterson. Cognitive functions of the subjects were accessed using Mini Mental State Examination (MMSE), Rey Auditory Verbal Learning Test (RAVLT), Digit Span, Digit Symbol Substituition Test (DSST) and Visual Reproduction; while mood states including tension, depression, anger, vigour, esteem related affect, fatigue and confusion were accessed using Profile of Mood States (POMS) questionnaire. Total positive subscales score, total negative subscales score and total mood disturbance (TMD) were also calculated. There were significant positive correlations between tension (r = 0.325, p = 0.30), vigour (r = 0.235, p = 0.036), esteem related affect (r = 0.316, p = 0.034) and total positive subscales score (r = 0.307, p = 0.040) with verbal episodic memory as measured using RAVLT fifth trial. In addition, positive correlations were also observed between vigour (r = 0.228, p = 0.035) and total positive subscales score (r = 0.237, p = 0.025) with DSST. After adjusted for confounding factors, subjects who scored higher in esteem related affect (Adjusted OR = 0.390, 95% CI [0.069-0.711], p = 0.019) and tension (Adjusted OR = 0.253, 95% CI [0.075-0.431], p = 0.007) had better verbal episodic memory. Subjects who have higher total positive subscales score were also had faster processing speed (OR = 0.856, 95% CI [0.099-1.614], p = 0.028). However after adjusted for confounding factors, the relationship was not significant (Adjusted OR = 0.383, 95% CI [-0.247-1.013], p = 2.226). Older adults with MCI who had a more positive mood tend to have a better short-term verbal memory and faster processing speed. DOI : http://dx.doi.org./10.17576/JSKM-2018-42

The investigation of the relationship between internalizing/externalizing problems and temperament, family functioning, child-rearing attitudes

Objective: This study was aimed to evaluate the relationship between internalizing/ externalizing problems and child temperament characteristics, family functioning and child-rearing attitudes. Methods: One hundred and fifty-seven children with internalizing and externalizing and their parents were included in this study. Internalizing and externalizing problems were evaluated by ‘Children Behavior Checklist’, child temperament was evaluated by ‘School-age Children Temperament Inventory’, family functioning was evaluated by ‘Family Assessment Device’ (FAD) and child-rearing attitudes were evaluated by ‘Parental Attitude Research Instrument’ (PARI). Results: Modelling test has been revealed that affective responsiveness feature subscales of FAD has a mediator effect on the relation found between in which both internalizing and externalizing problems, and marital conflict, rejection of the home making role and equalitarianism and democratic attitudes feature subscales of PARI. Similarly, modelling test has been pointed out that behavior control feature subscales of FAD has a mediator effect on the relation found between externalizing problems and strictness and authoritarianism feature subscales of PARI. Discussion: Our findings showed that family functioning has a mediator effect on the between internalizing/externalizing problems and child-rearing attitudes, these results indicated the importance of parent education in treatment. Long-term follow-up studies are required to determine relationships between internalizing /externalizing problems with child-rearing attitude and family functioning.

Cancer Rehabilitation: Impact of Physical Activity on Initial Clinical Assessments

ABSTRACT Background: Preconditioning and prehabilitation have been reported to ameliorate a host of health- and cancer-related issues, yet few studies have examined implications of past physical activity (PA) on physiological and psychological parameters in cancer survivors. Implications of prior PA on physiological and psychosocial variables in cancer survivors were acquired during an initial assessment prior to participation in a cancer rehabilitation program. Methods: Cardiorespiratory fitness (VO2peak), fatigue (Piper Fatigue Scale, PFS), and depression (Beck Depression Inventory, BDI) were measured (N = 807; 67 ± 13 years). PA groups were divided by self-reported prior PA history (Group 1 = none; Group 2 &amp;lt; 150 min/week; Group 3 ≥ 150 min/week). Results: Significant (P &amp;lt; 0.05) main effects for PA were observed among all variables except the PFS affective subscale. Groups 1 and 3 were significantly (P &amp;lt; 0.05) different for BDI. Groups 1 and 3 were significantly (P &amp;lt; 0.05) different for the total, sensory, and cognitive subscales of the PFS. Finally, Groups 1 and 3, and Groups 2 and 3 differed significantly (P &amp;lt; 0.05) for the behavioral, sensory, and cognitive subscales of the PFS. Conclusion: Cancer survivors with prior PA levels ≥ 150 min/week performed better on measures of VO2peak, were significantly less fatigued and depressed at initial assessment.

Measuring Intent to Aid of Lay Responders: Survey Development and Validation.

Increasing lay responder cardiopulmonary resuscitation and automated external defibrillator use during sudden cardiac arrest depends on an individual's choice. Investigators designed and piloted an instrument to measure the affective domain of helping behaviors by applying the theory of planned behavior (TPB) to better understand lay responders' intent to use lifesaving skills. Questionnaire items were compiled into 10 behavioral domains informed by the TPB constructs followed by refinement via piloting and expert review. Two samples from an American Red Cross-trained lay-responder population ( N = 4,979) provided data for an exploratory (EFA, n = 235) and confirmatory (CFA, n = 198) factor analyses. EFA derived interitem relationships into factors and affective subscales. CFA yielded statistical validation of factors and subscales. The EFA identified four factors, aligned with the TPB constructs of attitudes, norms, confidence, and intention to act to explain 57% of interitem variance. The internal consistency of factor-derived subscales ranged between 0.71 and 0.91. Reduction of instrument items went from 47 to 32 (32%). The CFA yielded good model fit with the switching of the legal ramification item from the social norm to intention construct. The Intent to Aid (I2A) survey derived from this investigation aligned with the constructs of the TPB yielding four subscales. The I2A allows health education researchers to differentiate modalities and content impact on learner intention to act in a first aid (FA) emergency. I2A compliments cognitive and psychomotor measurements of learning outcomes. The experimental instrument aims to allow curricula developers and program evaluators a means of assessing the affective domain of human learning regarding intention-to-act in an FA emergency. In combination of with assessment of functional knowledge and essential skills, this instrument may provide curricula developers and health educators an avenue to better describe intention to act in an FA emergency.

AFECTO POSITIVO COMO INDICADOR DE LAS ATRIBUCIONES ACADÉMICAS EN MATEMÁTICAS

Abstract.POSITIVE AFFECT AS AN INDICATOR OF THE ACADEMIC ATTRIBUTIONS IN MATHEMATICS The aim of the current study was to analyse the differences in the scores of academic attributions in Mathematics (success and failure attributed to capacity, effort and external causes) of Spanish students of primary education according to high and low scores in positive affect. To fulfil this target, a sample of 862 students of primary education (8-11 years old) was recruited. To obtain the scores of the analysed variables, the positive affect subscale of the Positive and Negative Affect Schedule for Children (PANAS) and the Mathematics subscale of the Sydney Attribution Scale (SAS) were used. After performing the Levene’s test, the Student’s t-test was used to analyse the existence of statistically significant differences in the scores of academic attributions between students with high scores in positive affect and students with low scores. In this sense, it was proved that students with high marks in positive affect attributed more their failures and successes in Mathematics to external causes. On the contrary, students with low levels of positive affect attributed more their failures to the lack of capacity or effort. The presented results broad the knowledge of affect during childhood and possibility the future work in improving these aspects. Keywords: positive affect; academic attributions; Mathematics; PANAS; primary education.Resumen. El objetivo del presente estudio fue el de analizar las diferencias de las puntuaciones en las atribuciones académicas en Matemáticas (éxito y fracaso atribuido a la capacidad, esfuerzo y causas externas) de estudiantes españoles de Educación Primaria en función de altas y bajas puntuaciones de afecto positivo. Para conseguir este objetivo, se recurrió a una muestra 962 de estudiantes de Educación Primaria (8-11 años de edad). Para obtener la medición de las variables analizadas, se utilizó la subescala de afecto positivo del Positive and Negative Affect Schedule for Children (PANAS) y la subescala de Matemáticas de la Sydney Attribution Scale (SAS). Tras llevar a cabo la prueba de Levene, se empleó la prueba t de Student para analizar la existencia de diferencias estadísticamente significativas en las puntuaciones de atribuciones académicas entre los grupos de altos y bajos niveles de afecto positivo. En este sentido, se descubrió que los alumnos con altas puntuaciones de afecto positivo atribuyeron más sus éxitos y fracasos en Matemáticas a causas externas. Por el contrario, los estudiantes con bajos niveles de afecto positivo atribuyeron sus fracasos a la falta de capacidad y esfuerzo. Los resultados del presente trabajo amplían el conocimiento del afecto en la infancia y posibilitan el trabajo futuro de mejora en estos aspectos.Palabras clave: afecto positivo; atribuciones académicas; Matemáticas; PANAS; Educación Primaria.

KOUJIN POWDER (RED GINSENG POWDER) WITH NINJIN-YOUEITO FOR FATIGUE DUE TO TARGETED THERAPY FOR ADVANCED RENAL CELL CARCINOMA: A RETROSPECTIVE COHORT STUDY

(Purpose) Targeted therapy has been standard therapeutic approach for advanced renal cell carcinoma (RCC). General fatigue is frequently observed in patients who receive targeted therapies for advanced RCC. General fatigue makes it difficult to continue a standard schedule of treatment in many cases. In this preliminary report, we explored the effect of Koujin powder (red ginseng powder) with Ninjin-youeito for general fatigue induced by targeted therapies for advanced RCC. (Material and method) The patients who complained of general fatigue during the treatment of Tyrosine Kinase Inhibitors (TKIs) as targeted therapies for advanced RCC were included in this retrospective analysis. Thirty patients with advanced RCC were enrolled from January 2016 to December 2016 at Chiba University Hospital. Twelve patients were given 3 g of Koujin powder with 9 g of Ninjin-youeito orally for two to four weeks (ginseng combination group). Eighteen patients who were not orally administered were compared as a control group (ginseng non-combination group). General fatigue was assessed with the Cancer Fatigue Scale (CFS), which divides quality of fatigue into three subgroups by using a "physical subscale", an "affective subscale", and a "cognitive subscale". We compared CFS scores at baseline and 2-8 weeks after administration. (Results) There was no statistical difference in the clinical variables between the two groups. The total CFS score was significantly decreased after treatment in the ginseng combination group (average score, 21.8 points at baseline vs 18.5 points after treatment; p=0.041). On subgroup analyses, the physical subscale score was significantly reduced after treatment in the ginseng combination group (average score, 9.7 points at baseline vs 7 points after treatment; p=0.0042). In the ginseng non-combination group, the total CFS score was significantly increased during the course (average score, 16.2 points at baseline vs 20.6 points during the course; p=0.047). On subgroup analyses, the physical subscale score was significantly increased during the course (average score, 4.4 points at baseline vs 7.3 points during the course; p=0.0042). (Conclusions) Koujin powder with Ninjin-youeito can be a therapeutic approach for general fatigue induced by targeted therapies. The precise management for general fatigue can keep patients on therapy, consequently provides a survival benefit.

Art museum-based intervention to promote emotional well-being and improve quality of life in people with dementia: The ARTEMIS project.

ARTEMIS (ART Encounters: Museum Intervention Study) is an art-based intervention designed especially for people with dementia and their care partners that involves a combination of museum visits and artistic activity. This paper reports the results of a randomized wait-list controlled study on the influence of the ARTEMIS intervention on the emotional state, well-being, and quality of life of dementia patients. People with mild-to-moderate dementia (n = 44) and their care partners (n = 44) visited the Frankfurt Städel Museum once a week on six pre-arranged occasions. The intervention consisted of six different guided art tours (60 minutes), followed by art-making in the studio (60 minutes). Independent museum visits served as a control condition. A mixed-methods design was used to assess several outcomes including cognitive status, emotional well-being, self-rated aspects of quality of life, and subjective evaluations by informal caregivers. In a pre-post-assessment, we found significant improvements in participants' self-rated quality of life (t = -3.15, p < .05). In a situational assessment of emotional well-being immediately before and after each of the museum sessions, we were able to demonstrate statistically significant positive changes with medium effect sizes (dcorr = .74-.77). Furthermore, the total Neuropsychiatric Inventory score as well as the affective (depressed mood and anxiety) and apathy subscales were significantly lower after the ARTEMIS intervention (tNPI total = 2.43; tNPI affective = 2.24; tNPI apathy = 2.52; p < .05). The results show that art museum-based art interventions are able to improve the subjective well-being, mood, and quality of life in people with dementia. This promising psychosocial approach deserves further attention in future studies and consideration in community-based dementia care programs.

Serotonin transporter binding and anxiety symptoms in Parkinson’s disease

BackgroundAnxiety is a common neuropsychiatric symptom in Parkinson’s disease (PD), yet the neural mechanisms have been scarcely investigated. Disturbances in dopaminergic and serotonergic signalling may play a role in its...