Adolescent Behavior Research Articles

Multivariate patterns linking brain microstructure to temperament and behavior in adolescent eating disorders

Abstract Eating disorders (EDs) are multifaceted psychiatric disorders characterized by varying behaviors, traits, and cognitive profiles driving symptom heterogeneity and severity. Non-invasive neuroimaging studies have been critical to elucidate the neurobiological circuitry involved in ED-related behaviors, but often focused on a limited set of regions of interest and/or symptoms. The current study harnesses multivariate methods to map microstructural and morphometric patterns across the entire brain to multiple domains of behavior and symptomatology in adolescents with EDs. Diffusion-weighted images, modeled with restriction spectrum imaging, were analyzed for 91 adolescents with an ED and 48 healthy controls. Partial least squares analysis was applied to map 38 behavioral measures (encompassing cognition, temperament, and ED symptoms) to restricted diffusion in white matter tracts and subcortical structures across 65 regions of interest. The first significant latent variable explained 46.9% of the covariance between microstructure and behavior. This latent variable retained a significant brain-behavior correlation in held-out data, where an ‘undercontrolled’ behavioral profile (e.g., higher emotional dysregulation, novelty seeking; lower effortful control and interoceptive awareness) was linked to increased restricted diffusion across white matter tracts, particularly those joining frontal, limbic, and thalamic regions. Individually-derived brain and behavior scores for this latent variable were higher in individuals with binge-purge symptoms, compared to those with only restrictive eating symptoms. Findings demonstrate the value of applying multivariate modeling to the array of brain-behavior relationships inherent to the clinical presentation of EDs, and their relevance for providing a neurobiologically-informed model for future clinical subtyping and prediction efforts.

Externalizing Problem Behaviors Among Chinese Early Adolescents in Poverty: Profiles and Longitudinal Change.

Children's externalizing problem behavior is one of the most explored topics among parents, educators, and research scholars. The purpose of this study is to examine the developmental changes of externalizing problem behavior in the early years of poor children and adolescents and the influence of family factors such as family functioning and parental marital quality on the developmental changes. Seven hundred and seventy-eight early adolescents (Mage = 13.7, SD = 2.53) from poor families were studied longitudinally for 14 months. The results showed that three potential characteristics of externalizing problem behavior patterns were identified through Latent Profile Analysis (LPA): well-adjusted group, attention disorder group, and conduct problem group. Latent Transition Analysis (LTA) revealed a tendency for the conduct problem group to transition to the well-adjusted group over two traces (OR = 0.40). There were gender differences in the results: boys in the conduct problem group were more likely to transition to the well-adjusted group (OR = 0.55), while girls in the attention disorder group were more likely to transition to the well-adjusted group (OR = 2.63). Research has found that a supportive family environment is a positive factor in mitigating externalizing problem behaviors of the early adolescents in their transition to adolescence.

Use of TikTok and its Effect on the Religious Behavior of Muslim Adolescents

This research aims to analyze the effect of the use of TikTok on religious behavior of Islamic youth in Gunung Tiga Village, Ulubelu sub district, Tanggamus district. The use of TikTok applications can have an impact whether it is the positive or negative impact. Because content is found in the application other than useful entertainment content. Sometimes there is content that does not deserve to be shown, especially to school children or teenagers. Because usually a TikTok user entertains himself by making a video that’s dancing and then uploads to its account and is seen by various TikTok users. Of course this shows a moral decline in religion. If the content is witnessed and imitated by teenagers then it will bring a negative influence to the teenager.

Karakteristik Tindakan Asusila di Bawah Umur di Rumah Sakit Bhayangkara Makassar Tahun 2024

Immoral behavior in children and adolescents includes actions that violate prevailing social and moral norms and demonstrate a disregard for ethical principles and societal rules. Complex interactions between genetic, environmental, and social factors influence the development of immoral behavior in children. This study has the main objective to obtain a comprehensive understanding of the characteristics of immoral acts experienced by underage victims who were recorded or treated at the Bhayangkara Hospital Makassar during one year, namely 2024. The approach taken in this study is a descriptive method with a retrospective design, where all data is collected systematically from cases that occurred and were recorded from January to December 2024. There were 192 victims of immoral acts involving children, 98.96% of whom were girls and 1.04% of whom were boys. Victims with an age group of <5 years were 5.73%, 5-12 years 33.33%, 13-17 years 60.94%. Victims of sexual violence in children 10.42% experienced physical violence, and 15.63% experienced verbal violence. The perpetrators were 81.77% of people known to the victim. There were more female victims of violence than male victims. The perpetrators of violence were often people known to the victim.

Psychological factors and parenting in shaping adolescent cyberbullying behavior on social media

The rapid advancement of technology has changed the world's civilization rapidly and provided many benefits to humans in various activities. Every individual, from children to adults will adapt to technology because daily life is very interchangeable to the use of technology, especially the internet to access social media, watch movies to find the latest news that spreads quickly. This study aims to identify the influence of Empathy, Self-Control and Parenting Style on adolescent Cyberbullying Behavior on Instagram social media. This study uses a quantitative method with a sampling technique, namely purposive sampling involving as many as 104 adolescent Instagram users as respondents. The instrument in this study is in the form of a questionnaire that is distributed through Google Form. The data of this study was tested using SPSS (Statistical Product and Service Solutions) software. The results of this study show that Empathy has a positive and significant influence on Cyberbullying behavior.Self-Control has a negative but not significant influence on Cyberbullying behavior. Parenting has a positive but also insignificant influence on Cyberbullying behavior. The results of this study indicate that the empathy factor is more dominant in influencing adolescent cyberbullying behavior when compared to self-control and parenting style.

IMPACTO DO VIDEOGAME VIOLENTO NO COMPORTAMENTO DO ADOLESCENTE

INTRODUCTION: Studies have shown that exposure to violent video games may be associated with increased aggression in adolescents. OBJECTIVE: To conduct a systematic, integrative study to highlight the impact of violent video games on adolescent behavior. METHODS: This is a systematic, integrative study using the Capes Periódico virtual library, Wiley online library, and Science Direct. Data collection was carried out in March and April 2022, and the inclusion criteria were articles published between 2017 and 2022. The exclusion criteria were articles that were irrelevant to the study theme, repeated, or contained inconsistent information regarding the guiding question. RESULTS: A total of 1,319 articles were analyzed; however, only 7 met the inclusion criteria and were selected for research based on their theme. The thematic categories developed from the analysis of the articles' conclusions were: 1- Exposure to violent games; 2- Parent-mediated media use. CONCLUSION: Generally speaking, there is no direct cause-and-effect relationship. Other factors, such as family history, social environment, and individual personality traits, can also influence adolescent aggressive behavior.

Attention Problems in Childhood and Subsequent Health Risk Behaviors in Adolescence

Objective: This study used a large U.S. population-based dataset to examine associations between childhood attention problems and adolescent substance use, sexual risk behavior, and delinquency. Methods: This prospective cohort study used data from the Future of Families and Child Wellbeing Study ( n = 2,716). Bivariate statistics, multivariable logistic regression, and negative binomial models assessed associations between attention problems at age 9 years and subsequent use of cigarettes, alcohol, and marijuana, engagement in sex without a condom, and delinquency at age 15 years. Results: Nearly one-fifth (18.3%) of adolescents had elevated scores (more than 1 standard deviation above the sample mean) for attention problems at age 9 years. Adolescents with elevated attention problem scores in childhood were more likely than adolescents who did not have elevated scores to have ever smoked an entire cigarette (9% vs. 4%) and ever tried marijuana (24% vs. 20%). Elevated attention problem scores were associated with higher odds of ever having smoked an entire cigarette (adjusted odds ratio [AOR] = 2.06, 95% CI [1.39, 3.05], p < .01) and higher delinquent behavior scores (incidence rate ratio [IRR] = 1.30, 95% CI [1.11, 1.53], p < .01). In adjusted models, there were no significant associations between elevated attention problem scores and ever having tried marijuana, consumed alcohol, or engaged in unprotected sex. Conclusions: This study found that elevated attention problem scores in childhood were associated with higher risk of cigarette smoking and delinquent behaviors in adolescence. Results provide support for screening for attention problems among elementary school-age children and early intervention strategies to prevent health risk behaviors in adolescence.

The Consequences of Peer Victimization for Suspension: Specifying a Pathway Through School Problem Behaviors in Early Adolescence

ABSTRACT Peer victimization and school suspension significantly impact youth development and life attainment. This study investigates how peer victimization increases the risk of school suspension among early adolescents, examining the mediating role of school problem behaviors. Using longitudinal data on 970 youth, we analyze whether victimization in 6th grade leads to increased problem behaviors in 7th grade, subsequently increasing the likelihood of suspension in 8th grade. Our findings reveal an indirect effect of peer victimization on suspension through school problem behaviors, suggesting that victimization can initiate a longitudinal chain of behavioral and disciplinary consequences. The results highlight the need for early intervention strategies addressing both victimization and its behavioral consequences, underscoring the importance of implementing trauma-informed practices and reconsidering punitive disciplinary policies for victimized youth.

The Chongqing Adolescent Twin Study: An Integrative Multimodal Brain Imaging and Non-imaging Dataset.

Adolescence is a pivotal phase of rapid brain development shaped by genetic and environmental factors, offering a critical window for identifying early indicators of psychiatric disorders. The Chongqing Adolescent Twin Study (CATS) explores genetic and environmental influences in 136 typically developing twins aged 12 to 19. This dataset includes multimodal MRI scans (structural, resting-state functional, and diffusion MRI) alongside extensive questionnaires on cognitive abilities, emotional and social behaviors, familial and parenting dynamics, sleep wellness, stress, anxiety, and depression. We describe the dataset in detail and systematically assess its quality. When benchmarked against the Lifespan Human Connectome Project Development (HCP-D) dataset, CATS meets or exceeds HCP-D standards in signal quality, tissue contrast, image sharpness, and head motion control. Preprocessing and imaging phenotype extraction facilitate broad reuse, and high phenotype correlations with HCP-D confirm reliability. This high-quality, multimodal resource provides a unique opportunity to investigate how genetic and environmental factors, along with age-related changes, shape adolescent brain structure, connectivity, and behavior, offering critical insights for precision medicine and early interventions in psychiatry.

Adolescence risk factors for meniscus and ligamentous knee injuries in adulthood: A longitudinal study.

Our aim is to investigate the influence of adolescent health-related behaviours on the occurrence of meniscus and ligament injuries in a large cohort of Finnish adolescents with an average 27-year follow-up. The baseline data were surveys conducted biannually from 1981 to 1997, and these were individually linked to outcomes, as well as meniscus and ligamentous knee injuries obtained from the Care Register for Health Care. A total of 47,747 participants were included. Of these, 22,020 were male and 25,727 were female. A Cox regression model was used to analyze the associations between exposure variables in adolescence (physical activity in sports clubs, other physical activity, overweight, smoking, monthly drunkenness, presence of chronic disease, family socioeconomic status) and the risk for knee injuries. Adjusted hazard ratios (aHR) with 95% confidence intervals (CIs) were computed. The mean follow-up time among the participants was 26.8 years (standard deviation [SD]: 4.1 years). A total of 1163 (2.4%) persons suffered a meniscus injury, and 1831 (3.8%) suffered a ligament injury. High physical activity in sports clubs (aHR: 2.02, CI: 1.85-2.21), overweight (aHR: 1.37, CI: 1.12-1.68), monthly drunkenness (aHR: 1.37, CI: 1.19-1.57) and presence of chronic disease (aHR 1.30, CI 1.08-1.56) increased the risk for meniscus injuries. Similarly, high (aHR: 1.72, CI: 1.60-1.84) physical activity in sports clubs, overweight (aHR: 1.26, CI 1.07-1.47), monthly drunkenness (aHR: 1.26, CI 1.13-1.41) and presence of chronic disease (aHR: 1.36, CI: 1.17-1.57) increased the risk for ligament injuries. Frequent physical activity in sports clubs presented a higher risk for meniscus and knee ligament injuries in individuals under 40, compared to degenerative factors such as being overweight or smoking. Interventions focusing on the suitable load level among adolescents with frequent and high-intensity physical activity, in addition to efforts to reduce negative habits should be prioritized to lower the knee injury risk. Level II.

Diabetes distress among caregivers of adolescents with type 1 diabetes.

Diabetes distress (DD), the negative emotional response related to the burdens of diabetes management, has been studied primarily in adults with type 2 diabetes and youth with type 1 diabetes (T1D), but less is known about DD among caregivers of youth with T1D. Caregivers of adolescents with T1D (n = 198, Mage = 45.6 ± 7.3, 84% female, 66% non-Hispanic White) were enrolled in a two-site randomized clinical trial aimed at treating DD among adolescents. The current study is a secondary analysis of baseline data to examine factors associated with DD among caregivers. Caregivers completed measures of DD, diabetes-related family conflict, and adolescents' diabetes self-management behaviors. Caregivers also reported on demographic factors, and clinical data were extracted from adolescents' medical records. Female caregivers, caregivers of younger adolescents, caregivers reporting lower household income, caregivers of lower subjective social status, and single/nonpartnered caregivers reported significantly higher caregiver DD. Further, after adjusting for demographic factors, higher diabetes-related family conflict and lower adolescent diabetes self-management behaviors were associated with significantly higher caregiver DD. Correlates of caregiver DD provide insight into potential risks and modifiable factors that may help clinicians develop interventions to target caregiver DD to improve outcomes in both caregivers and adolescents with T1D.

Assessment of the influential mechanisms of adolescent risk behaviors and protective and risk factors among high school students in Finnmark, Arctic Norway.

Adolescent risk behaviors, including alcohol use and antisocial behaviors, remain a public health concern in Finnmark, Arctic Norway. However, the mechanisms linking risk and protective factors to these behaviors remain underexplored. This study examines the influence of individual and environmental factors-such as family, peers, school, and local contexts-on adolescent alcohol use and antisocial behaviors. Using data from the 2021 Ungdata survey (N = 2,129 high school students), Partial Least Squares Structural Equation Modeling was applied to identify key associations. The results indicate that unstructured peer interactions, particularly spending evenings with friends, are strongly associated with both alcohol use and antisocial behaviors. In contrast, time spent on online gaming was associated with reduced risk of these behaviors, while social media use was positively linked to alcohol consumption. Experiences of sexual harassment, as well as other co-occurring risk behaviors such as smoking, drug use, bullying, and aggression, were consistently associated with increased engagement in both alcohol use and antisocial behaviors. Family and school environments showed limited associations with alcohol use but were linked to antisocial behaviors. Socioeconomic status and gender were not significantly related to either outcome, while depressive symptoms and religiosity showed selective associations, primarily with alcohol use. The findings underscore the need for peer-oriented preventive strategies and consideration of digital media exposure in addressing adolescent alcohol use and antisocial behavior. Future research should incorporate ethnicity-related variables to enhance contextual understanding of adolescent behaviors in the Finnmark region.

Factors Associated with Adolescent Sexual Behavior at SMP Muhammadiyah 1 Makassar

Unhealthy sexual behavior among adolescents, especially unmarried adolescents, tends to increase. Although sexual behavior and expression of sexuality are normal phenomena, the context in which sexual behavior is expressed can make behavior abnormal or risky. This study uses an analytical observational method with a Cross Sectional Study approach. The population in this study was the total number of students at SMP Muhammadiyah 1 Makassar, totaling 114 students. The sample in this study was part of the total number of students, namely 30 samples. The sampling technique used the Purposive Sampling technique. Data analysis was processed using SPSS using the Chi-Square statistical test. The results of this study showed that there was a relationship between Knowledge, Parental Roles and Information Sources on Adolescent Sexual Behavior with a ρ-value (0.001)> α (0.05).

Cocaine self-administration in adult female and male rhesus monkeys: longitudinal comparison with adolescent behavior and role of early life stress.

A phenomenon involving cocaine use disorders is the "incubation of drug craving" - the drive for the drug increases the longer the abstinence period. The present longitudinal study provided a unique opportunity to test whether an increase in the reinforcing effects of cocaine developed after prolonged abstinence and if early life stress was a risk factor. Fourteen (N = 6 female, 8 male) adult rhesus monkeys, some (N = 7) thatwere maltreated as infants by their mothers (MALT), had previously self-administered cocaine under a fixed-ratio (FR) schedule of reinforcement as adolescents, but had not been studied for >3 years. In Experiment 1, cocaine self-administration dose-response curves were redetermined in adulthood when responding was maintained under the identical FR 20 schedule used during adolescence. In Experiment 2, the reinforcing strength of cocaine was evaluated (n = 12) under a progressive-ratio (PR) schedule of reinforcement. While there were no statistical differences between male and female monkeys on FR responding in adolescents, when redetermined as adults, MALT monkeys showed higher peak response rates relative to adolescence. No such differences were noted in Control monkeys. Under the PR schedule, peak reinforcing strength was not different between groups or sexes. However, higher total adolescent cocaine intake was significantly associated with higher cocaine breakpoints in adulthood. These findings show that after adolescent cocaine self-administration and a long abstinence period, sensitivity to cocaine reinforcement increased, particularly in monkeys who experienced early life stress. Although early life stress (MALT) did not significantly impact measures of cocaine's reinforcing strength, higher adolescent cocaine intake did.

Physical activity, screen time and sleep among children and adolescents: findings from the 2022 active healthy kids Ethiopia

BackgroundFew studies have been conducted on movement behaviours in low-income countries, indicating a need for further surveillance. This study aimed to track changes since the release of Ethiopia’s 2018 Report Card indicators and explore further gaps in physical activity, sedentary screen time and sleep among Ethiopian children and adolescents (5–17 years).MethodsWe reviewed studies examining physical activity, sedentary screen time and sleep among Ethiopian children and adolescents. Relevant data were systematically searched from digital databases including PubMed, Medline, Scopus, Web of Science, WHO Hinari and Google Scholar, in alignment with the study objective. Policy or program documents were obtained from Ethiopian government official websites. Records were screened by two independent reviewers and extracted by the first author and verified by a co-author. Data were synthesised according to the harmonised Active Healthy Kids Global Alliance standards (A ≥ 80%, B 60–79%, C 40–59%, D 20–39%, F < 20%, INC = incomplete data).ResultsWe found eight studies (n = 8) with relevant information; all were based on parent- or self-reported data. Only a small proportion of them met the guidelines for physical activity (16%) and sedentary screen time (55%). There were no data available for sleep. Since the release of the 2018 Report Card, there have been improvements in the grades for School, Active Transportation, Sedentary Behaviour, Community and Environment, and Government indicators from D to A-, C to B-, F to C+, F to C-, and D to C, respectively. However, grades for Overall Physical Activity, and Organised Sport and Physical Activity decreased from D to F and from C to C-, respectively, while the rest of the indicators remained unchanged. The Sleep indicator was introduced for the first time.ConclusionSome indicators highlighted positive changes but limitations with data representativeness and quality underscore the need for improved surveillance to understand and promote healthy levels of movement behaviours in Ethiopian children and adolescents.

Faktor-Faktor yang Mempengaruhi Perilaku Merokok pada Siswa SMKN 3 Kota Jambi Tahun 2025

Jambi Province has the highest prevalence of tobacco smoking among individuals aged 15 years and above in Indonesia within the past month. In addition, Jambi also records the highest average number of cigarettes smoked per day by individuals in this age group, with an average of 18 cigarettes per day. This situation highlights the significant level of tobacco consumption in the province, which may affect adolescent smoking behavior, including among vocational school students. Objective: To analyze the factors influencing smoking behavior among students of SMKN 3 Kota Jambi. This study was a quantitative research with a cross-sectional design. The sample consisted of 114 students selected using random sampling techniques. The study was conducted at SMKN 3 Kota Jambi. The dependent variable was smoking behavior, while the independent variables included knowledge, parental influence, peer influence, and exposure to cigarette advertisements. Data were analyzed using univariate and bivariate analyses with the chi-square test at a 95% confidence interval. The proportion of students who smoked at SMKN 3 Kota Jambi in 2025 was 46.5%. There were significant associations between smoking behavior and knowledge (p-value = 0.008; PR: 1.730; 95% CI: 1.163–2.573), parental influence (p-value = 0.023; PR: 1.597; 95% CI: 1.081–2.357), and peer influence (p-value = 0.001; PR: 2.038; 95% CI: 1.346–3.086). However, no significant association was found between exposure to cigarette advertisements and smoking behavior (p-value = 0.127; PR: 1.366; 95% CI: 0.929–2.010).The factors influencing smoking behavior among students of SMKN 3 Kota Jambi were knowledge, parental influence, and peer influence.

Do gender and school type disparities influence the relationship between sleep quality and aggressive behavior? A moderation analysis

In China, the relationship between sleep quality and delinquencies such as aggressive behavior of Chinese high school seniors (CHSSs) has rarely been paid attention to. This research on the impact of sleep quality on aggressive behavior of CHSSs has filled the gaps in previous research on aggressive behavior of adolescents. Based on 2140 CHSSs samples collected from the southern cities in mainland China in 2024, the correlations between sleep quality and aggressive behavior were analyzed by using the multivariable regression models. According to the empirical results of this research, it can be known that sleep duration of most CHSSs in the total sample was less than 6 h, which was lower than the 2022 official statistics results that the average sleep of Chinese CHSSs was 6.5 h; CHSSs with poorer sleep quality may be more likely to involvement in aggressive behavior. Importantly, this study identified gender as a statistically significant moderator in the relationship between sleep quality and aggressive behavior including physical aggressive behavior, while the moderating effect of school types was not found to be statistically significant. These findings indicate that interventions and preventive measures should be tailored to different genders to effectively address the occurrence of aggressive and violent behavior among CHSSs with poor sleep quality. Also, the most CHSSs have reached the age for full assumption of civil and criminal responsibilities stipulated in the Chinese Civil and Criminal Law, and a considerable proportion of CHSSs may have poor sleep quality. Therefore, the high schools and relevant departments of government should formulate feasible and effective differentiated measures for different genders to improve sleep quality of CHSSs, for preventing and reducing the delinquent behavior including aggressive and violent behavior that may occur subsequently.

Body dissatisfaction and unhealthy weight-control behaviors of adolescents: The roles of exposure to influencer marketing and use of dating apps

This study examined adolescent exposure to influencer marketing and the use of dating apps by adolescents to establish possible relationships to body dissatisfaction (BD) and unhealthy weight-control behaviors (UWCBs). A total of 3121 high-school students were recruited from 36 schools in Taiwan. These students completed a self-administered questionnaire during the COVID-19 pandemic in 2022. Multivariate analysis revealed that adolescents who use dating apps, who have higher levels of exposure to influencer marketing of weight-control products, and who could be considered either overweight or obese are more likely to experience BD. Furthermore, adolescents who use dating apps, who have higher levels of exposure to influencer marketing related to weight-control products and experience BD are more likely to use weight-control products and engage in UWCBs. In conclusion, both the adolescent use of dating apps and exposure to influencer marketing are related to BD as well as to the purchase and use of weight-control products and to UWCBs. Our study findings have significant implications for future efforts to develop interventions that will enhance the ability of adolescents to resist the influence of digital marketing and encourage them to develop a healthier body image.

Who keeps smoking? A repeated cross-sectional analysis of adolescent behaviour in Indonesia

Adolescent smoking remains a significant public health issue, particularly in low- and middle-income countries such as Indonesia. This study examined how socio-demographic, economic, environmental, and psychological factors influence smoking initiation and persistence among adolescents. A repeated cross-sectional analysis was conducted using data from the Indonesian Family Life Survey (IFLS) waves 3 (2000), 4 (2007), and 5 (2014), focusing on adolescents aged 15–19 years. Smoking initiation was defined as having ever smoked, and persistence as continued smoking after initiation. Logistic regression was used to assess associations with age, gender, education, academic performance, parental smoking, income, school characteristics, area of residence, and depressive symptoms. Results showed that while overall initiation declined, older adolescents (17–19 years), males, and those from low-income households remained at higher risk. Being employed increased the odds of initiation, while higher education was protective. Persistence was more likely among males, unemployed adolescents, and those with smoking parents. Depression was associated with increased initiation but lower persistence, suggesting experimentation rather than long-term use. These findings highlight the roles of socioeconomic and mental health factors in shaping smoking behavior. Targeted tobacco control interventions and integrated mental health support are urgently needed, particularly for male adolescents and those exposed to parental smoking.

Neutrophil to-lymphocyte (NLR), monocyte-to-lymphocyte ratio (MLR), and platelet-to-lymphocyte ratios (PLR) as biomarkers for suicidal behavior in children and adolescents with depression or anxiety: A systematic review and meta-analysis

Introduction: Suicidal behaviour is a global phenomenon that has reached epidemic proportions due to the consistent rise in both completed and attempted suicides year after year, particularly among children and adolescents, who are the fifth leading cause of death in this demographic globally. Every year, over 700,000 individuals die by suicide, which equates to one death every 40 seconds on average. The neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), and monocyte-to-lymphocyte ratio (MLR) are blood markers of inflammatory status that are easy to use and reasonably priced. It was discovered that patients with depression or anxiety have higher NLR, MLR, and PLR. Thus far, there have been relatively few studies assessing biomarkers for the prognosis for suicidal behavior in children and adolescents with depression or anxiety and shown varying results. The aim of this meta-analysis is to assess NLR, MLR, PLR as predictive biomarkers for suicidal behavior in children and adolescents with depression or anxiety. Methods: A literature search was conducted through databases, such as PubMed, Cochrane, ScienceDirect, Ebsco, Springerlink to identify relevant topics up to March 2025. The inclusion criteria for this meta-analysis study were (1) studied patients with suicidal behavior in children and adolescents with depression or anxiety, (2) the study had to be a type of observational study that was reported the relationship between suicidal behavior in children and adolescents with depression or anxiety and NLR, MLR, PLR, (3) providing sufficient information about mean and standard deviation, (4) the publication language of studies is limited to English. The quality of research methods was assessed using a modified form of the Newcastle Ottawa Scale (NOS). The statistical analysis in this study was conducted using RevMan 5.4 software. Results: A total of 13 studies including 1192 depressed or anxiety patients with suicidal behavior and 1200 controls were included, with the majority of studies coming from Turkey. Our analysis revealed that depressed or anxiety patients with suicidal behavior had significantly higher NLR (SMD = 0.43, 95% CI: 0.15–0.72, p = 0.003), PLR (SMD = 11.31, 95% CI: 7.48-15.14, p &lt; 0.00001), MLR (SMD = 0.02, 95% CI: 0.01-0.03, p &lt; 0.00001) compared with controls. Risk bias assessment utilizing the NOS scale indicated that all studies showed good quality with minimal bias. Conclusion: Higher NLR, PLR, MLR were significantly associated with an increased risk of depressed or anxiety patients with suicidal behavior. Therefore further research is needed to develop this topic.