Adhesive Strips Research Articles

Clinical case of Malassezia otitis media in a dog

Dermatopathologies are pretty standard among domestic dogs and cats. Today, Malassezia occupies a leading place among fungal skin lesions. Particular attention should be paid to Malassezia otitis since fungal infections are usually a marker of low resistance, so against their background, it is natural to increase the pathogenic effect of other microflora and, as a result, damage to the eardrum, middle ear, and other destructive changes in the hearing organs. The article presents the results of the use of a bioregulatory approach in the complex therapy of malassezia otitis in dogs with the use of the drug “Traumeel”, which contains ultra-low doses of biologically active substances. The use of this drug increases the safety of treatment, which in turn protects the animal's body from complications and adverse effects of therapy. The study was conducted based on a private outpatient clinic of veterinary medicine in Ternopil during the treatment of an 11-year-old dog with chronic otitis. The clinical manifestation of Malassezia otitis was determined by characteristic clinical signs (hyperpigmentation, hyperemia, edema, pain, and increased ceruminous secretion). A cytological examination with light microscopy of adhesive strips with biomaterial fixed on a slide and stained with a modified Wright-Giemza stain, “Leukodif”, was performed to confirm the diagnosis. For therapy, initially, a generally accepted standard therapy was used using 1 % ketoconazole and 2 % chlorhexidine twice a day and preliminary cleaning of the auricles. Since no positive dynamics were observed, Traumeel 1 ml intramuscularly 1 time per day for 5 days was additionally used for therapy. The choice of bioregulatory drug was based on the components and their action. After 7 days, the dog's inflammation significantly decreased – edema, hyperemia, and itching disappeared, and there was no pathological accumulation of ceruminous gland secretion. Subsequently, three more injections of Traumeel were performed with an interval of 48 hours. 3 weeks after the diagnosis, a repeated cytological examination for the presence of Malassezia was performed – the result was negative. Subsequently, the dog underwent hygienic ear cleaning 1–2 times a week. There were no relapses. Based on the therapy results, it can be concluded that the treatment regimen for Malassezia otitis is effective.

Experiment and enhancement of compressive strength perpendicular to the grain of inorganic-bonded bamboo composite

ABSTRACT The inorganic-bonded bamboo composite (InorgBam) is a novel type of bamboo-based composite: a combination of magnesium oxysulfide inorganic adhesive and bamboo fiber strips, which exhibits significant material anisotropic characteristics with compressive strength perpendicular-to-grain typically lower than that of parallel-to-grain. The impact of loading form including full-area compression, middle and end local compression on strength perpendicular-to-grain was examined. The enhancement of compressive strength perpendicular to the grain using the glued-in rods (GiRs) method was tested. A prediction formula for ultimate load-carrying capacity perpendicular to the grain of enhanced InorgBam material was proposed considering the influence of load form and depths of GiRs. Results indicate that the full-area compression perpendicular to the grain exhibits a higher load-carrying capacity compared to the middle and end local compression. The GiRs method significantly enhances the compression strength and deformation behavior perpendicular to the grain of InorgBam material. The compressive load-carrying capacity and elastic modulus of the enhanced specimens can be increased by 83% and 157%, respectively. The prediction formula based on the replacement ratio of GiRs can well predict the strength of enhanced specimens.

Research on reversible bonding of microfluidic chips based on stretch release adhesive strips

AbstractThe reversible bonding of microfluidic chips has been developing rapidly with the requirement of reusable microfluidic devices or the need to obtain the samples inside the chip. Traditional bonding methods for polymer‐based microfluidics, e.g., thermal bonding, permanently attach the substrate and cover plate. Sometimes, once the chip flow channel is blocked, it is difficult to clean and affect the reusability of the chip. This study proposes a new reversible bonding method for poly (methyl methacrylate) (PMMA) microfluidic chips with the help of stretch release adhesive strips. The designed microchannels were fabricated on the surface of PMMA plates using CO2 laser irradiation. Then, stretch release adhesive strips were used as an intermediate layer between the substrate (with microchannels) and another flat PMMA/PS/PC plate to seal the microchannel. The assembled chip sets were bonded at room temperature with bonding strength comparable with other permanent bonding methods. Experimental results show that simply pulling the adhesive layer by applying a shear force can easily detach the intermediate adhesive layer from both the substrate and cover plate to separate the bonded chipset. The proposed reversible bonding method is simple, rapid and has low residue and high bonding strength. Bacterial culture experiments were also conducted to verify the biocompatibility of the proposed bonding method. The proposed reversible bonding technique can be used for polymer‐based microfluidic devices that require sample recovery or chip reuse.Highlights The stretch release adhesive strip can provide high bond strength. It allows easy peeling for reversible bonding. It bonds at room temperature with simple operation. It has good transparency for easy observation of experiments. It has good biocompatibility.

IMPLANTABLE MEDICAL DEVICES: A NON INVASIVE AND COSMETIC FRONTIER FOR WOUND CLOSURE

Abstract Cardiovascular implantable electronic devices (CIEDs) implantation procedures have undergone continuous improvement. Every aspect of the procedure can contribute to these improvements, including incision closure. The aim of this study was to assess the accuracy and validity of a non–invasive method using adhesive skin closure strips for wound closure of CIEDs in older adults, instead of surgical suture, evaluating parameters such as infection, erythema, skin reaction, itching, pain, oedema, time for closure, cosmetic outcomes and patients’ satisfaction. A retrospective study was carried out in 152 subjects (mean age 81 +9.3 years).undergoing application of adhesive strips after CIEDs substitution/implant and 132 usual care control subjects (mean age 76.6+8.9). Variables considered were: age, gender, risk factors for wound complications. Wound evaluation was conducted by using the Visual Analogue Scale (VAS) and the Patient and Observer Scar Assessment Scale (POSAS). Operative time for closing the incision and for removing sutures or strips were significantly lower in both application and removal in the adhesive strip group. At follow–up evaluations, each parameter considered by evaluation of the patients and staff was significantly better than in the control group. Fewer complications were observed in the patients undergoing wound closure wit adhesive strips. Previoulsy, to the best of our knowledge, the use of adhesive strips in closing surgical wounds of patients undergoing CIEDs implant/replacement has never been considered. Adhesive strips for wound closure of CIEDs incision are characterized by shorter procedural time, optimal early and late cosmetic results, fewer complications in older patients and is cheaper. Its use for CIEDs wound closure is reasonably supported.

Comparison between liquid skin adhesive and wound closure strip for skin closure after subcuticular suturing in single-port laparoscopic appendectomy: a single-center retrospective study in Korea.

This study was performed to evaluate the safety and feasibility of skin adhesives and to compare postoperative and cosmetic outcomes after wound closure in single-port laparoscopic appendectomy (SPLA) between skin adhesives and steri-strips. This was a single-center retrospective study. We included 22 and 47 patients in whom skin adhesive and steri-strips were used respectively, for skin closure after subcuticular suturing in SPLA between August 2014 and 2020. The patient scar assessment questionnaire (PSAQ) was completed postoperatively to assess postoperative cosmetic outcomes. On the postoperative day, patients in whom skin adhesive was used had significantly lower numeric rating scores than in whom steri-strips were used (2.8 ± 0.8 vs. 3.9 ± 0.8, p < 0.001). The frequency of analgesic administration within 24 hours and between 24 and 48 hours after surgery was significantly lower in the skin adhesive group compared to the wound closure strip group (1.4 ± 0.8 vs. 2.7 ± 1.2, p = 0.013 and 0.2 ± 0.4 vs. 0.7 ± 0.9, p = 0.002, respectively). In the PSAQ, "satisfaction with appearance" and "satisfaction with symptoms" subitem scores were significantly lower in patients in whom skin adhesive was used (11.3 ± 3.0 vs. 15.1 ± 4.5, p = 0.006 and 6.5 ± 1.8 vs. 9.5 ± 3.3, p = 0.003), whereas, "appearance" and "consciousness" subitems revealed no statistically significant differences between the groups. Liquid skin adhesive closures seem to be safe and feasible and cause less postoperative pain, resulting in greater patient satisfaction with postoperative scars than wound closure strip closure after subcuticular suturing in SPLA.

Wearable Technology for Monitoring Electrocardiograms (ECGs) in Adults: A Scoping Review.

In the rapidly evolving landscape of continuous electrocardiogram (ECG) monitoring systems, there is a heightened demand for non-invasive sensors capable of measuring ECGs and detecting heart rate variability (HRV) in diverse populations, ranging from cardiovascular patients to sports enthusiasts. Challenges like device accuracy, patient privacy, signal noise, and long-term safety impede the use of wearable devices in clinical practice. This scoping review aims to assess the performance and safety of novel multi-channel, sensor-based biopotential wearable devices in adults. A comprehensive search strategy was employed on four databases, resulting in 143 records and the inclusion of 12 relevant studies. Most studies focused on healthy adult subjects (n = 6), with some examining controlled groups with atrial fibrillation (AF) (n = 3), long QT syndrome (n = 1), and sleep apnea (n = 1). The investigated bio-sensor devices included chest-worn belts (n = 2), wrist bands (n = 2), adhesive chest strips (n = 2), and wearable textile smart clothes (n = 4). The primary objective of the included studies was to evaluate device performance in terms of accuracy, signal quality, comparability, and visual assessment of ECGs. Safety findings, reported in five articles, indicated no major side effects for long-term/continuous monitoring, with only minor instances of skin irritation. Looking forward, there are ample opportunities to enhance and test these technologies across various physical activity intensities and clinical conditions.

Non-inferiority analysis of adhesive strips vs. sutures in lumbar spinal fusion: A propensity matched study

Non-inferiority analysis of adhesive strips vs. sutures in lumbar spinal fusion: A propensity matched study

The effect of using denture adhesives on patient satisfaction with complete dentures; a randomized clinical trial

BackgroundDenture adhesives can be useful in improving patients’ satisfaction with complete dentures. However, comparison clinical trials are lacking. The purpose of this randomized clinical trial was to assess the satisfaction of edentulous patients and their oral health impact profile when provided with 3 types of denture adhesives.MethodsSixty-four completely edentulous patients seeking complete dentures for their first time were randomly divided into 3 groups. Each group received a set of complete dentures, which were adjusted at review appointments until participants reported no complaints. After 1 month of using the dentures, participants rated their overall satisfaction and their satisfaction regarding comfort, retention, stability, and efficiency of mastication and speech on a 100-mm visual analog scale (VAS). Participants also filled out the oral health impact profile for edentulous patients (OHIP-EDENT) questionnaire. Each group was then given 1 type of denture adhesive to use. Group C received Corega Ultra denture fixative cream (GlaxoSmithKline), Group O received Olivafix (Bonyf), and Group S received Sea. Bond adhesive strips (Sea.Bond). Mann-Whitney U test was used to analyze the differences in VAS scores before and after using the adhesive within each group and Wilcoxon-signed rank test was used to compare OHIP scores and total OHIP values before and after using the adhesive within each group (p = 0.05). Furthermore, Kruskal Wallis test was used to compare the differences before and after using the adhesives in VAS and OHIP values between the 3 groups.ResultsSignificantly higher VAS values were detected in all groups and significantly lower values for many OHIP items in addition to total OHIP values were detected in all groups after using the adhesives (P < 0.05), except for the ease of cleaning for Group O and Group S (P > 0.05). No significant differences were found in VAS and OHIP values between the 3 groups (P > 0.05), except for the ease of cleaning which was significantly different between Group C and Group S (p = 0.005).ConclusionsUsing denture adhesives for completely edentulous patients resulted in higher patient satisfaction as indicated by higher VAS scores as well as improved quality of life as indicated by lower OHIP-EDENT scores after using the adhesives. These improvements were not dependent on the type of adhesive, except for ease of cleaning as adhesive strips were easier to clean than paste type adhesives.Trial registrationThis trial was registered at ClinicalTrials.gov (ID: NCT05496283) on 11/08/2022.

Pyrolysis and combustion characteristics of typical sealing materials for exterior building windows

Seals play a crucial role in preventing flame penetration through building exterior windows. However, as urban renewal accelerates, the number of discarded seals is also gradually increasing, which is not in line with the concept of green, energy-saving sustainable development. To gain a better understanding of the pyrolysis and combustion characteristics of sealing strips and facilitate their effective resource utilization and conversion into value-added fuels, we employed thermogravimetry, cone calorimetry, and flue gas spreading test equipment. Typical sealing and filling materials used for external windows of buildings, including EPDM ordinary adhesive strips (EPDM-O), EPDM flame-retardant adhesive strips (EPDM-R), as well as 20-fold expanding graphite strips and 30-fold expanding graphite strips (EG-20 and EG-30), were investigated. Comprehensive evaluations of their pyrolysis behaviors, kinetic parameters, and combustion characteristic parameters were carried out. The results showed that EPDM exhibits good thermal stability, while EG had better demonstrates favorable pyrolysis properties and expansion densification. Average activation energies of EPDM-O and EPDM-R in the combustion phase were 68.35 kJmol−1 and 92.40 kJmol−1, respectively. Moreover, the average activation energies of EG-20 and EG-30 in the expanding combustion phase were 67.42 kJ·mol−1 and 68.62 kJ·mol−1, respectively. The reaction rate of combustion stage is faster than that of pyrolysis stage. Furthermore, For the combustion, the flame growth index (FGI) of EPDM is greater than that of EG, whereas the flame spread index (FPI) is lower than EG. When EPDM burns, the flame spreads rapidly, while EG expands and generates a large number of wormlike substances, effectively preventing the high temperature from spreading to the interior of the material. Analyses of smoke spreading tests have shown that both EPDM and EG can produce irritating flammable fumes at high temperatures, affecting the environment. These results provide a basis for the development of new materials and contributes to fire safety, smoke management, and personnel escape planning.

ELIMINATION OF THE DEFECTIVE LAYER AND STRESS CONCENTRATORS DURING MICROMACHINING OF HOLES IN THIN SHEET BLANKS OF METAL CELLULAR PANELS

Thin-sheet blanks made of aluminum (in particular, AMg2-N), titanium (VT-15, VT-19) or stainless (12X17) alloys are widely used in the production of honeycomb panels in the aviation and space industries. Foil (thickness 0.025-0.055 mm) is used for the production of fillers for cellular sandwich panels; it is pre-perforated with holes of 0.05-0.18 mm and laid out in a corrugated box with adhesive strips. The possibility of making holes by the laser jet method is considered, as it precedes the occurrence of mechanical damage and thermal defects of the surface adjacent to the treatment zone. It is shown that the Water Jet Guided Laser (WJGL) is an effective and efficient method of obtaining profile holes in the fillers of cellular panels and in the panels themselves, which is characterized by high productivity and allows obtaining holes without thermal and mechanical defects. The method can be used both for foil fillers and for metal panels made of stainless steel up to 1.5 mm thick.

Awareness in general population about the home modifications which are necessary to prevent falls in community dwelling elderly

Background: Falls are considered to be one of the “geriatric giants”. The living room, bathroom, bedroom and staircase are common areas where falls occur within home. Many elderlies who fall even if they remain uninjured, become apprehensive causing them to cut down on their activities of daily living and becoming less active, weaker, further increasing their chances of falling. Therefore, it’s of paramount importance to scrutinize the awareness about the home modifications. The study was conducted to examine if the general population is aware of the home modifications necessary to prevent falls in community dwelling elderly. Methods: A cross sectional study was conducted in 300people between 30 to 50 years old who were not medical professionals. Convenience sampling was used. A self-structured questionnaire was prepared and clearance of ethical committee was obtained. After taking people’s consent they were asked to fill the questionnaire. Results: Results show that out of 300 participants people are aware of non-slippery floors (70%), railings at the staircase (62%). People are least aware of the following modifications: glare free paints (20%), door knobs can be replaced with lever handle (40%), install adhesive strips on the staircase (30%). Conclusions: Results show that out of 300 participants people are aware of non-slippery floors (70%), railings at the staircase (62%). People are least aware of the following modifications: glare free paints (20%), door knobs can be replaced with lever handle (40%), install adhesive strips on the staircase (30%).

Evaluation of insertable cardiac monitor placement and safety in the LUX-Dx PERFORM study

Abstract Funding Acknowledgements Type of funding sources: Private company. Main funding source(s): Boston Scientific Corporation Background The LUX-Dx PERFORM Study is designed to evaluate safety and performance of the LUX-Dx insertable cardiac monitor (ICM) in a general patient population. Enrollment and device insertions are complete, and all patients have completed 30 days of follow-up. This abstract describes the study population, characterizes device insertion, and reports on preliminary data for ICM system-related complications. Methods The LUX-Dx PERFORM study is a prospective, multi-center, single arm, post-market, observational study. The ICM system-related complication-free rate (CFR) at 30 days post-insertion was calculated using Kaplan-Meier methodology and the 97.5% one-side lower confidence limit (LCL) was compared to the prespecified performance target of 94%. All ICM system-related adverse events were adjudicated by independent physician reviewers. Results 727 patients were enrolled at 24 centers in the United States from March 2021 to May 2022. The study population was 49% male, 91% white and 66+/-14 years old. 717 patients had device insertions and were successfully registered in the LATITUDE Clarity data management system. There were 9 withdrawals prior to insertion and 1 aborted procedure due to deployment difficulty. ICM insertion was performed in-hospital 76% of the time (N=547) and in-clinic 24% of the time (N=171). 96% were de novo device insertions. A variety of closure techniques were used including surgical glue (62%), adhesive strips (45%), sutures (42%), and staples (9%). Median procedure time was 4 minutes (range 1 - 37). There were 4 ICM system-related complications in the first 30 days (CFR 99%, LCL 99%) which meets the acute safety performance goal. The system-related complications include 1 case of ICM deployment difficulty, 1 case of device expulsion three days post insertion, and 2 infections that were treated with oral antibiotics and resolved without further mitigation. Conclusion The LUX-Dx ICM can be inserted quickly, in both hospital and clinic settings, with a very low complication rate.

Non-Invasive Diagnosis of Sun Damaged Skin: Actinic Keratosis Vs Squamous Cell Carcinoma.

Actinic keratosis (AK) is a premalignant lesion that has a1% to 10% potential of progression to squamous cell carcinoma (SCC), but it is not possible to determine which lesions are at higher risk. This study examined the epidermal genetic profiles of actinic keratosis and SCC through non-invasive techniques seeking to develop a biopsy-free method for AK monitoring and aid in the early diagnosis of developing SCC. Ribonucleic acid (RNA) was collected from adhesive tape strips and gene expression levels were measured. A threshold fold change &gt;2 and adjusted P-value &lt;0.05 were used to determine differentially expressed genes. Single center dermatology clinic. Patients who presented to the clinic with lesions suspicious of non-melanoma skin cancer that had never been previously biopsied. RNA was extracted via non-invasive biopsy and sequenced. Low quality samples were filtered out and the remaining samples underwent differential gene expression analysis by DESeq2 in R package. A threshold of fold change &gt;2 and adjusted P-value &lt;0.05 was used for determination of differentially expressed genes. The differentially expressed genes that overlapped between the corrected and uncorrected groups were the most significant for analysis. From 47 lesions, 6 significant differentially expressed genes were found between AK and SCC, and 25 significant differentially expressed genes between in-situ SCC and invasive SCC. Individual samples showed similarities based on diagnosis, suggesting mutations were specific to the disease and not the individual. These findings highlight which genes may play a role in AK progression to SCC. The genomic differences between in-situ and invasive squamous cell carcinoma open an opportunity for early diagnosis of squamous cell carcinoma and risk prediction of actinic keratosis. J Drugs Dermatol. 2023;22(5): doi:10.36849/JDD.7097.

The conidial coin toss: A polarized conidial adhesive in Colletotrichum graminicola

Colletotrichum graminicola is an economically significant fungal pathogen of maize. The primary infective conidia of the fungus, falcate conidia, are splash-dispersed during rain events. The adhesion of the falcate conidia triggers germination and is required for the development of infection structures. Falcate conidia are capable of immediate adhesion upon encountering the substrate. We report that rapid adhesion in C. graminicola is polarized, with a single-sided strip of adhesive material running the length of a single side (or face) of the conidium between the tips. This strip of adhesive is co-localized with dynamic transverse actin cables, and both the adhesive strip and actin cables are formed after liberation of the conidium from its conidiogenous cell but prior to adhesion to the infection court. Orientation of conidia upon contact with substrate determines whether they will rapidly adhere, and those which do not initially adhere can be induced to do so by applying force to reorient or “flip” the conidia. We propose that C. graminicola possesses an adhesive mechanism resulting in an adhesion efficiency of approximately 50% upon initial contact with substrata, and that an increase in adhesion efficiency can be induced by disturbance.

Enhanced bamboo interfacial bonding performance on the basis of toughening phenol formaldehyde resin by flour

AbstractPhenol formaldehyde (PF) resin adhesive is the most commonly used adhesive in bamboo gluing due to its excellent bonding strength and durability. However, its high brittleness after curing could cause stress concentration at the bonding interface between PF resin and bamboo, which seriously affect the bonding performance. In this study, different quantity of flour was incorporated into PF resin adhesive and homogeneous processed, the toughening effect and mechanism of the flour on PF resin together with the influence on the bonding strength were fully investigated. Differential scanning calorimeter analysis indicated that flour could make the curing reaction of PF resin much milder. Fracture morphology characterization of PF resin by scanning electron microscopy showed that the flour had good dispersibility and compatibility in PF resin adhesive, which could directly contribute to the mechanical properties of PF resin specimens by forming a ductile fracture. When 10 wt% flour was incorporated, the flexural and impact strength increased by 83.42% and 92.01% compared with the pure PF resin, respectively. The decreased quantity and size of the cracks in cured PF resins on bamboo surface after the incorporation of flour observed by Ultra‐depth‐of‐field microscope and quasi‐static nanoindentation of bonding interface proved that flour could effectively toughen the PF resin and reduce the formation of defects and cracks inside the resin, thus improve the bonding strength. Correspondingly, the bonding strength of the PF resin adhesive glued bamboo strips increased by 14.5% when 10 wt% flour was added into the PF resin.

Fabrication of antibacterial Janus bandages with high wound healing performances by facile single-side electrospray PDMS coating

Bandages are widely utilized to cover local wounds. However, most bandages have limited capacities to promote wound healing, which may occasionally cause serious wound infections. Accordingly, herein, we demonstrated a facile electrospray method to fabricate an antibacterial Janus bandage that could simultaneously remove wound bed exudate and prevent wound infection. The advanced bandage was only composed of an adhesive strip and an antibacterial Janus cotton fabric, whose single side was controllably electrospray-coated with a thin polydimethylsiloxane coating. The Janus cotton fabric exhibited a high one-way transport index (R = 1068%), suggesting its appropriate directional liquid moisture transport ability, and excellent air permeability. Furthermore, in vitro experiments demonstrated that the advanced bandage had adequate biocompatibility and exhibited sustained release of hydroxypropyltrimethyl ammonium chloride chitosan, which considerably enhanced the proliferation of fibroblasts. As a proof-of-concept, this bandage was employed to drain the exudate from Staphylococcus aureus (S. aureus)-infected mice wounds and kill S. aureus in these wounds, which significantly accelerated wound healing. The simple fabrication process of unique bandage reveals it has considerable potential as a next-generation bandage for healing local wounds clinically.

COMPARISON OF AESTHETIC OUTCOME BETWEEN SUBCUTICULAR SUTURES VERSUS STERILE TISSUE ADHESIVE STRIPS IN POST THYROIDECTOMY WOUND CLOSURE

Introduction: To study and compare aesthetic outcome between subcuticular sutures and sterile tissue adhesive strips in thyroidectomy wound closure using validated scoring system (POSAS). RCT study conducted in a tertia Materials: ry care, teaching hospital on patients &gt;18 years of age undergoing thyroidectomy. 106 patients each were randomised into two groups with compara Results: ble baseline parameters. Conclusion: Cosmetic benet and aesthetic outcome between both techniques were similar. Sterile tissue adhesive strips had less pain and excellent scar appearance following thyroidectomy surgery.

Cosmetic Outcomes of Simple Pediatric Facial Lacerations Repaired With Skin Adhesive Compared With Skin Adhesive With Underlying Adhesive Strips: A Randomized Controlled Trial.

A randomized controlled trial was designed to compare 2 methods of repairing simple pediatric facial lacerations. We hypothesized that wounds repaired with skin adhesive and underlying adhesive strips compared with skin adhesive alone would be superior in regard to cosmetic outcome. Patients aged younger than 18 years presenting to the emergency department with simple facial lacerations requiring repair were eligible for enrollment. Patients were randomly assigned to repair with either skin adhesive alone or skin adhesive with underlying adhesive strips. Families were contacted by phone 1 week after enrollment to discuss short-term complications. The cosmetic appearance of photographs of the scars at 2 months was analyzed using a visual analog scale by a blinded pediatric emergency physician and pediatric plastic surgeon. One hundred twenty patients were enrolled, with 92 returning for the 2-month follow-up. The visual analog scale scores for the skin adhesive with adhesive strips group were similar to the skin adhesive alone group (60 mm vs 58 mm, P = 0.540). Spearman ρ correlation coefficient between the raters was 0.669, indicating strong agreement. There was no significant difference in rates of return visits, wound dehiscence, or infection. The skin adhesive with adhesive strips group had a longer time to perform the repair (195 seconds vs 107 seconds, P < 0.001). Using adhesive strips to first approximate a wound before applying skin adhesive leads to a similar cosmetic outcome compared with simple facial lacerations repaired with skin adhesive alone. Although the study showed longer time to complete the repair, this approach may still be useful in settings where approximation is difficult to obtain manually.

Closed-Incision Negative-Pressure Therapy Reduces Donor-Site Surgical Wound Dehiscence in DIEP Flap Breast Reconstructions: A Randomized Clinical Trial.

In breast reconstruction operations, surgical wound dehiscence is a serious complication that generates a significant burden on patients and health care systems. There are indications that postoperative treatment with closed-incision negative-pressure therapy has been associated with reduced wound dehiscence rates. This randomized clinical trial examines the effect of closed-incision negative-pressure application on abdominal donor-site surgical wound dehiscence in low- and high-risk patients undergoing breast reconstruction with a deep inferior epigastric perforator flap. Eighty eligible women, stratified as low- or high-risk patients, were included and were randomized for treatment with either closed-incision negative-pressure or adhesive strips by drawing sealed, opaque envelopes. All surgeons were kept blinded for allocation. Primary outcomes were surgical wound dehiscence and surgical-site infection at the abdominal donor site on follow-up after 12 weeks. Secondary outcomes were seroma and hematoma formation. Five patients were excluded from the study because of insufficient exposure to the study treatment ( n = 4) or major protocol deviation ( n = 1). A total of 75 women, low-risk ( n = 38) and high-risk ( n = 37), received either closed-incision negative-pressure ( n = 36) or adhesive strips ( n = 39). Patients' demographics did not differ significantly. Donor-site surgical wound dehiscence occurred in 23 patients; the absolute risk reduction was statistically significant (21.6 percent; 95 percent CI, 1.5 to 41.7 percent). No statistically significant differences were found in surgical-site infection or secondary outcomes. In this randomized clinical trial, postoperative treatment with closed-incision negative-pressure therapy decreased the incidence of surgical wound dehiscence at the abdominal donor site in low- and high-risk deep inferior epigastric perforator flap breast reconstruction patients. Therapeutic, I.

Adhesive strips for wound closure of cardiovascular implantable electronic devices.

Adhesive strips for wound closure of cardiovascular implantable electronic devices.