Additional Stress Research Articles

Examining the optimum panel pillar dimension in longwall mining considering stress distribution

Longwall mining method is widely used for underground coal production in the world. Additional stresses occur surrounding the longwall during underground mining. Stresses occurring surrounding the longwall are investigated by many researchers for years. How these stresses affect longwall production, gob, main gate, tailgate and main haulage road has been always an important issue. In this study, the effect of the safety pillar left at the end of the panel on the main haulage road is investigated. For this purpose, 6 models with different pillar distances are created and the stresses occurring in the main haulage road, tailgate and main gate at different pillar distances are examined. It has been demonstrated with numerical models that the optimum pillar distance according to these stress conditions does not damage the main haulage road, tailgate and main gate. In addition, the pillar distance of 10 m gives maximum coal recovery efficiency, and it has been shown by numerical models that the stresses occurring in the main haulage road, main gate and tailgate are not damaging to these galleries.

Experiences of Financial Stress and Supports in Caregivers During Pediatric Hospital Admission.

In Canada and the United States, ∼1 in 5 children live in poverty, contributing to poor health outcomes. Families with children with chronic illness may experience additional financial stress related to hospitalization. This study aimed to capture experiences of financial needs and supports among caregivers with a child admitted to a tertiary care pediatric hospital to inform hospital-based financial services to reduce financial stress in families. We recruited caregivers of children admitted to the general inpatient ward of an academic pediatric center using purposive sampling with no exclusion criteria. Individual, semistructured, in-depth interviews with participants were conducted. Data collected included socio-demographics, financial needs, and experiences with financial supports. Interviews were audio-recorded, transcribed verbatim, coded, and analyzed on NVivo software using a modified-grounded theory approach and summative content analysis. Fifteen caregivers of diverse backgrounds were interviewed, including non-English speakers (n = 4). Three themes and associated subthemes (in parentheses) were identified: (1) financial stress expressed by participants (acute admission-related and chronic financial stress), (2) challenges associated with accessing and utilizing financial supports (caregiver factors, systemic hospital factors, and systemic government factors), and (3) ideas for financial services at the pediatric hospital (services that will provide acute- and chronic financial assistance including education about financial supports and benefits). Our study highlighted acute and chronic financial needs as well as challenges in accessing financial support. Participants were interested in the healthcare system gaining a comprehensive understanding of their financial circumstances and accessing financial services in a hospital setting.

Theoretical Study on Diaphragm Wall and Surface Deformation Due to Foundation Excavation Based on Three-Parameter Kerr Model

To calculate the horizontal displacement of the diaphragm wall and surface settlement caused by foundation pit excavation, the three-parameter Kerr foundation model was applied to a diaphragm wall and derived the flexural differential equations of the diaphragm wall and calculated the horizontal displacement of the diaphragm wall using the finite difference calculation method. The boundary element method combined with the Mindlin displacement solution was then used to invert the additional horizontal stress near the diaphragm wall. Lastly, the Mindlin solution was used to calculate the surface settlement. The effectiveness of the proposed calculation method was verified by comparing the horizontal displacement of the diaphragm wall and the surface settlement between the theoretical calculation and the actual project. The theory proves that there is a certain connection between the horizontal displacement of the diaphragm wall and the surface settlement, and the horizontal displacement of the diaphragm wall is larger than the surface settlement. Using this theory to further analyze the foundation pit construction parameters, the greater the thickness and elasticity modulus of the diaphragm wall, and the greater the diameter and number of internal supports, the smaller the horizontal displacement of the diaphragm wall and the surface settlement. The theory can accurately predict the horizontal displacement of the diaphragm wall and surface settlement and provides guidance for the construction of foundation pit projects.

Obesity affects brain cortex gene expression in an APOE genotype and sex dependent manner.

Obesity is the top modifiable risk factor for Alzheimer's disease. We hypothesized that high fat diet (HFD)-induced obesity alters brain transcriptomics in APOE-genotype and sex dependent manners. Here, we investigated interactions between HFD, APOE, and sex, using a knock-in mouse model of the human APOE3 and APOE4 alleles. Six-month-old APOE3-TR and APOE4-TR mice were treated with either HFD or control chow. After 4 months, total RNA was extracted from the cerebral cortices and analyzed by poly-A enriched RNA sequencing on the Illumina platform. Female mice demonstrated profound HFD-induced transcriptomic changes while there was little to no effect in males. In females, APOE3 brains demonstrated about five times more HFD-induced transcriptomic changes (399 up-regulated and 107 down-regulated genes) compared to APOE4 brains (30 up-regulated and 60 down-regulated). Unsupervised clustering analysis revealed two gene sets that responded to HFD in APOE3 mice but not in APOE4 mice. Pathway analysis demonstrated that HFD in APOE3 mice affected cortical pathways related to feeding behavior, blood circulation, circadian rhythms, extracellular matrix, and cell adhesion. Female mice and APOE3 mice have the strongest cortical transcriptomic responses to HFD related to feeding behavior and extracellular matrix remodeling. The relative lack of response of the APOE4 brain to stress associated with obesity may leave it more susceptible to additional stresses that occur with aging and in AD.

(286) Impact of Hormonal Treatment in Patients with Gender Dysphoria in the First Six Months of Treatment

Abstract Introduction Gender dysphoria (GD) is a mismatch of how we feel our identity, male or female, with the biological sex. This incongruity can lead to discomfort and suffering. Prejudice and discrimination may result in additional stress, with impact on quality of life (QV). Hormonal therapy (HT) is an important part of the treatment of patients with GD and can have an impact on sexual life and QV. Objective To assess the impact of HT on sexual desire and quality of life in patients with GD throughout the first 3 to 6 months of treatment. Methods Longitudinal study of quality of life (QL) and sexual desire (SD), before and 3 to 6 months after starting HT, using the WHO WHOQOL-BREF questionnaire, which assesses the physical, psychological, social and environmental domains, of DS (dyadic and solitary) through the Sexual Desire Inventory- 2 (SDI-2) questionnaire and obtaining sociodemographic, clinical and laboratory data on patients who came to our consultation with a diagnosis of GD. Results 52 patients, with a mean age of 25.11 (18–56) years, completed the WHOQOL-BREF and SDI-2 questionnaires. 30 FtM (57.7%) and 22 MtF (42.3%). Almost half 49% (n= 26) had a comorbid psychiatric disorder. In FtM the average total testosterone (TT) increased from 0.320 ng/mL to 7.190 (+/- 2.340) ng/mL and in MtF the average TT increased from 6.86 ng/mL to 0.59 (+/- 41) ng/mL 3 to 6 months after starting HT, without serious side effects. FtM showed a significant increase in DS (p < 0.01), both dyadic and solitary, while MtF showed a non-significant decrease in SD after the start of HT. There was a non-significant improvement in the physical, social relationships and environment domains and a significant improvement in the psychological domain (p < 0.01). In the physical domain, FtM patients showed a significant improvement compared to MtF patients. 20% of patients reduced or stopped psychiatric medication. Despite the negative impact of HT on SD in MtF, there was an improvement in QoL and a reduction in the need for psychiatric medication. In FtM there was a significant improvement in the psychological and physical domain. Conclusions HT is safe, improves QoL and reduces the need for psychiatric medication in patients with GD. This improvement was significant in the psychological domain. Disclosure No.

Pregnancy maintenance and fetal loss assessment in Holstein cows through analyzing pregnancy-associated glycoproteins in milk

Fetal loss (FL) from the 45th day of gestation until calving can impose a significant economic burden on dairy farmers, resulting in lost profits and increased production costs. Pregnancy-associated glycoprotein (PAG) is commonly used for detecting pregnancy in cows. PAG is secreted by binucleated trophoblast cells of the placenta and regulated by more than 24 genes. The purpose of this study was to determine the PAG threshold for FL and a probability of pregnancy maintenance until calving based on milk PAG levels. Our results reveal that primiparous and multiparous cows that maintained pregnancy until the 40th week exhibited higher PAG sample-negative (SN) values in their milk in the 6th week of gestation than did those that experienced FL later in gestation. Pregnant cows with higher PAG SN values in the 6th week of gestation were more likely to maintain their pregnancies. The area under the receiver operating characteristic curve for predicting the probability of pregnancy maintenance was 0.722 for our prediction model. On the other hand, a milk PAG SN value of <0.192 indicated 95 % confidence that FL would occur between the 7th and 40th weeks of gestation. Milk PAG testing is a noninvasive sampling technique that does not induce additional stress in lactating cows. The study reveals that PAG SN values increase significantly in Holstein cows during the 6th week of gestation. The predictive model developed was effective in forecasting pregnancy outcomes up to the 40th week of gestation or calving. The model's performance is moderately good for field application and could be a useful tool for dairy producers.

Fourth-grade nanofluid model with dissipative and nonlinear radiative properties transported peristaltically via a flexible diverging duct holding a porous media under the influence of concentration and heat convection in an induced magnetic field

The major goal of this work is to give a thorough examination of the effect of double diffusion convection (DDC) in addition to a generated magnetic field on peristaltic movement of fourth-grade nanofluid across a vertical sophisticated asymmetrical microchannel using a nondeformable porous media as a basis for intricate pumping systems inspired by biological processes for hazardous waste. The mathematical formulas pertaining to flow, heat/mass transfer under the influence of viscous dissipation, nonlinear heat radiation, and Joule heating were developed using Buongiorno’s framework for nanofluids with combining the thermophoresis and Brownian motion characteristics. Mathematical analysis has been conducted under the suppositions of an extended wavelength and a relatively small Reynolds number. Magnetic field induced axially, density of current, magnetic force function, thermal characteristics, nanoparticles proportion gradient, an additional stress tensor, pressure gradient, and stream function are all given explicit formulas. The constructed function (ND Solve function) within the Wolfram software (Mathematica) is employed to computationally resolve the ensuing system of coupled nonlinear differential equations. Numerical and pictorial evidence is presented to highlight the significance of different physiological characteristics of flow volumes. Further, contour visualizations and circulation bolus have been used to highlight the trapping phenomena, one of among the most noteworthy peristaltic motion occurrences. The main results showed that, despite the dissolvent concentration and the volume percentage of nanoparticles having the opposite effects, the resistance of a substance to heat is shown to climb as the Soret and Dufour numbers rise. At larger levels of the electromagnetic Reynolds number, Strommer’s number, electric field parameter, and thermal Grashof number, stronger axial induced magnetic fields (IMFs) are also provided.

Enhancing Semiconductor Package Reliability through Mechanical Property Optimization of Pressureless Sintering Die Attach Adhesives

There is growing demand for high-power devices, wide bandgap SiC and GaN semiconductor materials in semiconductor market, and a drive to integrate die attach materials that can replace lead-containing solders. However, epoxy-based and solder materials face challenges to meet high thermal conductivity and survive elevated working temperatures. Pressure-assisted silver sintering has overcome these challenges, but downsides of pressure-assisted silver sintering are that it requires special equipment and for some applications, packages are unable to withstand the pressure required to facilitate sintering. Pressureless sintering materials could be processed using the same equipment as traditional die attach adhesives. It develops strong metal bonds to substrates, providing high thermal conductivity and withstanding high temperatures. However, compared to pressure-assisted sintering, pressureless materials may have difficulties to form a dense bondline structure if the formulation design is not optimized. Moreover, once the sintered structure is built during cure, further bondline reduction may induce additional stress. Therefore, it is critical that the pressureless sintering material’s mechanical properties are formulated to effectively manage stress and pass all reliability testing – especially for automotive packages. This paper will present the findings from a study that evaluated the impact of various formulation components – such as silver packing and resin chemistry – on the mechanical properties and interfacial bonding of pressureless sintering die attach adhesives. The effect on in-package reliability performance was also investigated to better understand material properties that can pass reliability testing while maintaining high thermal and electrical conductivity adhesive requirements.

Numerical Simulation of the Simultaneous Development of Multiple Fractures in Horizontal Wells Based on the Extended Finite Element Method

Simultaneous multiple-fracture treatments in horizontal wellbores have become an essential technology for the economic development of shale gas reservoirs. During hydraulic fracturing, fracture initiation and propagation always induce additional stresses on the surrounding rock. When multiple fractures develop simultaneously, the development of some fractures is limited due to the stress-shadow effect. An in-depth understanding of the multiple-fracture propagation mechanism as reflected by fracture morphology and flow rate distribution can help to set reasonable operation parameters for improving the uniformity of multiple fractures and forming a complex fracture network according to the different in situ stress conditions in a reservoir to increase the shale gas recovery and reduce the cost. In this study, a two-dimensional (2D) fracture propagation model was developed based on the extended finite element method (XFEM). Then, the influences of various factors, including geological and operational factors, on the development of multiple fractures were studied. The results of numerical simulations showed that increasing the cluster spacing or injecting fracturing fluid with lower viscosity can help reduce the stress-shadow effect. In the case of smaller in situ stress differences, the deflection of the fractures was larger due to the stress-shadow effect. As the stress difference increased, the direction of the propagation of the fracture was gradually biased towards the direction of maximum horizontal stress. In addition, the injection rate had some effects on the fracture morphology and flow rate distribution. However, as the injection rate increased, the dominant fracture developed rapidly, and the fracture length significantly increased.

Macro-microscopic mechanical behavior of geogrid reinforced calcareous sand subjected to triaxial loads: Effects of aperture size and tensile resistance

Reinforcing calcareous sands with geogrids is a potentially effective method for large-scale geotechnical constructions in coastal lands. The breakable nature of polygonal calcareous sands determines the complex particle-geogrid interactions. A three-dimensional numerical model of geogrid reinforced calcareous sand (GRCS) was established to investigate the potential mechanical laws based on the discrete element method (DEM), and the reasonableness of the numerical model was verified by comparing with the indoor triaxial test. It follows that the macro-microscopic mechanical behavior of GRCS under the influence of aperture size and tensile resistance of geogrids was further investigated via effective DEM simulations. The presented results show that the decreased aperture size and increased tensile resistance are beneficial to enhance the macro-mechanical properties of GRCS, including strength, internal friction angle and pseudo cohesion. Particle crushing is mainly affected by shear strain and confining pressure. The bulging deformation of GRCS is partially suppressed due to the confining effect of geogrids. Besides, the source of strength enhancement of GRCS is revealed based on the microscopic particle-geogrid interactions, and the calculation method of horizontal and vertical additional stresses in the reinforced soil element considering the effects of tensile resistance and aperture size is further established.

LSTM-based deformation forecasting for additional stress estimation of existing tunnel structure induced by adjacent shield tunneling

A redistribution of stress is caused by the excavation of a new tunnel within the soil surrounding the existing shield tunnel structure. This stress redistribution results in alterations to the soil and water loads around the existing tunnel structure, ultimately impacting its stress and deformation. The deformation response of existing tunnels is primarily focused on in most existing studies, with limited research conducted on the coupling system of new tunnel excavation, soil stress state, and deformation and stress of existing tunnels. This paper proposed an innovative methodology to predict deformation in existing tunnel structures and estimate additional stress during the excavation of a new shield tunnel. The reliability of the suggested calculation method was verified using measured internal force and convergence data of the structures. The results demonstrated that the Long Short-Term Memory (LSTM) model could more effectively establish the temporal correlation between the excavation parameters of new tunnels and the deformation of existing tunnels. Compared to the Recurrent Neural Network (RNN) model, the R2 of the LSTM model increased by 11.81% in the prediction of the tunnel waist and 9.38% in the prediction of the tunnel crown. The Light gradient boosting machine (LightGBM) algorithm was used to analyze the crucial factors of deformation of the existing tunnel structures during shield tunneling, and the results showed that the relative position and the average earth pressure were the essential factors. Furthermore, a calculation method for the additional stress of existing tunnel structures was proposed based on the load structure model. The method assumed that the additional load was distributed rectangularly at the top and bottom of the existing tunnel, and triangularly at the waist of the tunnel. The comparison between the calculated results and the measured results indicated that the phased characteristics of the internal force changes in the existing tunnel structure during the construction of a new tunnel could be accurately reflected by this method.

Diversities and sustainability of dietary water footprint and virtual water flows in China

Increasing dietary diversity while avoiding additional stress on water resources remains a critical challenge for sustainability. However, the precise understanding of the physical water consumption and virtual water flows associated with diversified diets remains unclear. This study estimated the dietary water footprints (WFs), interprovincial virtual water flows, followed by assessing the unsustainable blue WF and water scarcity footprint (WSF) in China over 2015–2019. Rural and urban food intake, waste, and differences between eating at home and out were considered. The findings reveal that China’s dietary patterns have gradually strayed from recommended guidelines, with an overconsumption of cereals and inadequate intake of dairy products and potatoes. Despite a decrease, both unsustainable blue WF and WSF remained significant, measuring 249.61 Gm3 and 807.77 Gm3 H2O-eq, respectively, in 2019. Notably, water-scarce regions still accounted for a substantial portion of unsustainable virtual blue water exports. The diet related virtual water reallocation can offset the water savings on the crop production side.

No additional stress of sublethal gas supersaturation in a landlocked population of Atlantic salmon (Salmo salar) exposed to environmental acidification

The landlocked Atlantic salmon population “bleke” faces extinction due to environmental acidification (EA) and hydropower expansion in the Norwegian river Otra. Despite of restoration, unexpected mortality has been reported for this population, possibly due to gas bubble trauma (GBT) from gas supersaturation (GSS) downstream of hydroelectric plants, or EA induced aluminum toxicity. In this study, we applied the allostasis concept to investigate interactions between EA and GBT. This concept comprises additive effects of stressors, which can lead to allostatic overload. Stress coping mechanisms become maladaptive in such situations, which can be indicated by an inability to mount a proper cortisol response in fish. Fish were exposed to sublethal levels of simulated EA (SEA), GSS (a total gas pressure; TGP; of 110%) or a combination of these stressors for six days. Effects on allostatic load were subsequently investigated by assessing the cortisol response to an acute stress test. SEA increased cortisol responsiveness and GSS induced clinical signs of GBT, but no interacting effects between GSS and SEA were observed. This suggests that that 110% TGP did not have an additive effect on the allostatic load imposed by SEA.

The Impact of Stigma on Sexual and Gender Minority Communities During the COVID-19 Pandemic

The global COVID-19 pandemic has resulted in life-altering changes for millions of people. Historically, marginalized groups prove to be among the most vulnerable populations during times of crisis due to the additional stress, isolation, fear, and stigma they already face in society. Through focus group research, this study sought to explore how one marginalized group, the LGBTQIA community, has been affected by the pandemic. The study found that although members of the LGBTQIA community did not face any specific COVID-19 stigma, the pandemic exacerbated the already disproportionate socioeconomic issues they faced. Already at risk of being socially isolated, the pandemic created a further division between participants and their personal relationships. In addition, participants faced the loss of jobs and health insurance, which increased their health risk. Participants expressed maintaining routines and relying on the resiliency they have built up over a lifetime of facing social stigma as ways that they were able to cope with the pandemic.

Heading for the Frontline: Mood, Stress, Resilience, and Coping of Nursing Graduates during a Global Pandemic

COVID-19 affected health and wellbeing globally. Graduating nursing students face a variety of stressors, and entering the nursing profession during the pandemic adds additional stress. Using a quantitative cross-sectional design, mood, perceived stress, resilience, and coping were assessed in an Australian sample of 112 graduating nursing students, who completed the Brunel Mood Scale (BRUMS), Perceived Stress Scale (PSS-4), and Brief Resilient Coping Scale (BRCS). Mean BRUMS scores for tension, fatigue, and confusion were significantly above population norms and vigour scores were significantly below. Mean PSS-4 scores were reflective of population norms but showed higher levels of stress among younger and on-campus students compared to those who were older or studied externally. BRCS data showed that 82.1% of graduating nursing students were medium- or high-resilient copers. Mood profiles suggested that 19.6% of participants reported moods associated with mental health issues, 23.2% reported moods associated with risk of burnout, and only 17.9% reported mood profiles associated with positive mental health. High mean tension scores reported by graduating nursing students indicated apprehension about joining the profession, although stress, resilience, and coping scores suggested they were adequately managing the additional stressors generated by the global pandemic.

Evaluation Model on Activation Classification of Coal Mine Goaf Ground Considering High-Speed Railway Loads

The construction and expansion of high-speed railway networks in China has been occurring at a fast pace, resulting in some lines crossing through coal mine goaf sites. However, the embankment and train loads may trigger the activation of the coal mine goaf ground, posing a threat to traffic safety. To ensure the safety of construction and railway lines, an evaluation model on the activation classification of coal mine goaf ground, taking into account the high-speed railway load, is proposed, which is mainly applicable for middle–deep and level goaf areas using a longwall mining method. Firstly, 12 influencing factors are selected as the underlying evaluation indexes, and the catastrophe progression method model for evaluating the coal mine goaf ground stability is constructed. The findings of the evaluation were found to align with the actual results, indicating the reliability of the model. Then, the additional stress calculation model for high-speed railway ground with different embankment heights, train speeds, and axle loads was established, and the train load disturbance depth with a 5% criterion was determined. The influence degree of load on high-speed railway was divided, and the weight of each factor was determined. Finally, the extension comprehensive evaluation method was used to unite the stability grade of the coal mine goaf site and the influence degree of the train, so the evaluation model on activation classification was proposed. The accurateness and reliability of the proposed model was verified using the Taijiao high-speed railway cases and the model test.

Teachers’ Psychological Distress and Work-Related Experiences During the COVID-19 Pandemic in Quebec (Canada)

COVID-19 has put additional stress on teachers, whose levels of psychological distress are concerning. However, studies that look at teachers’ work experiences and their association with psychological distress during the pandemic are lacking. This study aims to draw a portrait of psychological distress (i.e., symptoms of depression and anxiety) and work-related experiences (i.e., work engagement, workplace discrimination, interpersonal conflicts at work and quality of relationships among school staff) in a sample of preschool, primary and secondary school teachers in Quebec during the pandemic across socio-demographic characteristics (age, gender, years of teaching experience, school level, region, immigrant status). In addition, we investigated whether work-related experiences were associated with psychological distress. A total of 818 teachers ( Mage = 44.5; SD = 9.04; 82.8% women) responded to an online questionnaire. Linear and logistic regression analyses were implemented. Results showed concerning levels of both anxiety and depressive symptoms in our sample. Gender, immigrant status and school level differences in the perception of the work environment emerged. Higher reported work engagement, fewer interpersonal conflicts at work and a better quality of relationships among school staff were all independently and statistically significantly associated with lower psychological distress. Promoting a cohesive school climate among school personnel can protect teachers from psychological distress in times of adversity. A socio-ecological approach to research and intervention that considers work experiences in terms of both engagement and quality of relationships is warranted to improve teachers’ well-being and contribute to a positive learning environment in schools for adults and students alike.

A comparative analysis of accelerating humid and dry heat stress in India

Extreme humid heat stress poses distinct challenges to human health and productivity that cannot be mitigated solely by heat action plans designed for dry heat stress. This study investigates the trends in extreme heat stress, differentiating between dry and moist heat, in India from 1943 to 2022 using the high-resolution hourly ERA5 reanalysis data. The analysis utilizes the Heat Index (HI) as a key parameter to identify instances of extreme humid heat stress, characterized by HI values exceeding 41 degrees Celsius and relative humidity more than 50%. The findings indicate that certain eastern coastal regions in peninsular India experience extreme humid heat stress from May to June due to persistent high humidity levels. In addition, northwest, northcentral and inland eastern coastal regions encounter extreme dry heat stress preceding the monsoon season, followed by a transition to humid heat stress immediately after the onset of the monsoon. The results also show that there has been a significant increase ofsix times (on average) in the extreme humid heat stress hours per grid over the past 80 years compared to a threefold increase in dry heat stress. Our research underscores the need to shift from exclusively addressing dry heat stress to adopting a comprehensive approach that considers the impacts of humid heat stress.

The Effect of Workload, Dual Role Conflict and Job Stress on the Performance of Female Lecturers at X University

Objective: Women who take on the role of wife and mother as well as workers, tend to lead them to dual role conflict. If the workload continues to increase without an appropriate division of workload, the performance of lecturers will decrease. This study attempts to determine the effect of workload, dual role conflict and job stress on performance in female lecturers at X University.&#x0D; &#x0D; Method: The research design was a cross-sectional study with a sample size of 100 proportionally selected female lecturers. The SPSS program was used to process data univariately and the AMOS program was used to process data multivariately using path analysis.&#x0D; Results: Then, the results showed that there is an affects between workload and work stress (questionnaire) (p=0.003), family-work conflict on work stress (questionnaire) (p=0.005), workload affects performance (p=0.001) work stress (cocorometer) affects performance (p=0.005), work stress (questionnaire) affects performance (p=0.004), while there is no effect between family-work conflict on work stress (questionnaire) (p=0, 802), workload has no effect on work stress (cocorometer) (p=0.696), work-family conflict has no effect on work stress (corometer) (p=0.570), family-work conflict has no effect on work stress (cocorometer) (p=0.433), work-family conflict has no effect on performance (p=0.357), and family-work conflict has no effect on performance (p=0.124). Based on the intervening test, the indirect effect of workload on performance through job stress is -0.080, the indirect effect of work-family conflict on performance through stress is 0.053 and the indirect effect of family-work conflict on performance through stress is -0.025.&#x0D; &#x0D; Conclusion: In addition, there is a significant influence between workload and dual role conflict on performance through job stress. Further investigation is being conducted into additional variables that may affect performance other than the above independent variables. Implication of the research: This research can contribute to improving conflict management that can impact the quality of performance in the workplace. The results of this study can help employees and the general public by educating them about the elements that can lead to excessive workload, the occurrence of multiple role conflicts that can reduce the quality of worker performance.&#x0D; &#x0D; Originality: This journal presents a study of workload, dual role conflict and work stress on performance in female lecturers at universities. considering that previous studies have only examined work stress using questionnaire measurement tools, there are additional work stress measurement tools so that they can be comparable This study discusses the effect of workload and dual role conflict on performance through work stress. The findings explain the importance of balancing workload with work as a lecturer and housewife in order to create quality performance.

Doping zinc oxide and titanium dioxide nanoparticles with gold induces additional oxidative stress, membrane damage, and neurotoxicity in Mytilus galloprovincialis: Results from a laboratory bioassay

BackgroundWhile previous studies have provided insights into the effects of zinc oxide (ZnO) and titanium dioxide (TiO2) nanoparticles (NPs) on aquatic organisms, there is still a substantial amount of information lacking about the possible effects of their doped counterparts. The goal of the current work was to address this gap by examining Mytilus galloprovincialis reaction to exposure to doped and undoped nanoparticles. MethodsTwo concentrations (50 or 100 µg/L) of undoped ZnO and TiO2 NPs, as well as their gold (Au) doped counterparts, were applied on mussels for 14 days, and the effects on biomarkers activities in digestive glands and gills were assessed by spectrophotometry. ResultsThe NPs were quasi-spherical in shape (below 100 nm), stable in seawater, and with no aggregation for both doped and undoped forms. Analytical results using inductively coupled plasma atomic emission spectroscopy indicated the uptake of NPs in mussels. Furthermore, it was found that biometal dyshomeostasis could occur following NP treatment and that doping the NPs aggravated this response. At the biochemical level, exposure to undoped NPs caused membrane damage, neurotoxic effect, and changes in the activities in the gills and digestive glands of superoxide dismutase, catalase, and glutathione-S-transferase, in a concentration and organ-dependent manner. ConclusionDoping ZnO NPs and TiO2NPs with Au induced additional oxidative stress, membrane damage, and neurotoxicity in mussels.