Additional Knowledge Sources Research Articles

Effect of katakaphala eye drops on Digital eye strain- A pilot study

The mandatory e-learning has emerged as a method for teaching during coronavirus disease 19 (COVID-19) pandemic. That now has become the usual routine for additional knowledge source for students, who spend most of the time (4-5 hrs per day) attending e-classes or reading e books in front of a computer or mobile screens. These devices cause harm by emitting short high energy waves that makes an individual vulnerable to a variety of eye problems ranging from dry eye to age-related macular degeneration. It is collectively known as digital eye strain (DES). Katakaphala (strychnos potatorum) is an herb commonly used for ophthalmic conditions like irritation, pain, redness etc. This study was aimed to conduct survey on digital eye strain among BAMS students and to evaluate the effect of katakaphala eye drops on digital eye strain. The survey was conducted using a questionnaire and first 100 students with features of digital eye strain were included for the study. Detailed examination including visual acuity ad shirmers test was done for the enrolled subjects. Katakaphala eye drops was administered to the subjects 2drops in each eye, 4 times a day for 15 days. All parameters were documented on before treatment, at the end of treatment and on day of follow up (30th day). There was significant improvement in all parameters clinically and statistically except in redness of eye. By virtue of properties of the ingredients this katakapahala eye drops helped in relieving Headache, Eye strain & Redness in digital eye strain and improved vision.

Bacterial Endospores as an Additional Source of Archaeological Knowledge in the Analysis of a Burial Cemetery of the Tarnobrzeg Lusatian Culture in Dębina (SE Poland)

Archaeological studies need to use laboratory techniques, including analytical methods like Atomic Absorption Spectrometry, gas chromatography – mass spectrometry, and high-performance liquid chromatography, as well as genetic methods to resolve and verify scientific hypotheses. However, additional tools are still needed in the case of the cultural practicesand traditions of ancient societies. Archaeological examinations of cultural practices have made significant progress in recent years, but additional tools are still needed to fully understand the complexity and diversity of these practices. In this work, we demonstrate how the genotyping of soil bacteria that can produce endospores is a potentially additional method for discovering past funeral rituals in various human populations who used food during their ceremonies. Endospores were isolated from soil samples taken from inside earthenware cup and pot-type vessels from a burial ground identified with the Tarnobrzeg Lusatian culture (SE Poland). The detected species of spore-forming bacteria strains were mostly environmental (originating from soil and / or water). However, the presence of some of the taxa i.e. (Peanibacillus, Bacillus) may provide a valuable source of archaeological information. We found that a combination of molecular and microbiological analysis can support archaeological studies of burial grounds and – in particular – individual graves, especially when they are characterized by a complete lack of bones.

Russian paroemias as a means of activating grammatical and lexical skills in the process of teaching foreign students

Introduction. Currently, Russian paroemias are actively used in the process of teaching Russian as a foreign language in order to improve lessons, increase motivation to learn the language, illustrate typical situations of communication, activate cognitive and thinking abilities of foreign students. The purpose of the article is to describe the process of activating grammar and lexical skills of foreign students with the help of paroemias at different stages of learning. Research methods. In the course of the research we used: the method of directional sampling of material from paroemiological collections and dictionaries; methods of structural, semantic and contextual analysis of proverbs and sayings. Results. Paroemias reflect the folk wisdom, mentality, world outlook, life experience, notions of the surrounding reality, basic values of the Russian people, being important material, which promotes the development of language and communicative and speech skills of foreign students. Various types of assignments with Russian paroemias are used as a means of developing communication skills and abilities, as well as a source of additional scientific knowledge about natural objects, taking into account the direction of student training. Conclusion. The use of Russian paroemias in the process of teaching Russian as a foreign language is the basis for the formation of linguocultural and communicative competence, contributes to the activation of grammatical and lexical skills, the development of monologue and dialogic speech skills, the expansion of the lexicon, the formation of moral principles, the education of tolerant attitude towards language, culture, history, traditions and customs of other nations. The integration of oral folklore in the educational process is relevant for foreign students at different stages of learning. The vocabulary of paroemias is a special language layer, which can also be used by foreign students in their future professional sphere.

What ethical requirements should be considered in language classroom assessment? insights from high school students

There has been a growing call for listening to test-takers’ voices across diverse assessment contexts. Within classroom assessment (CA), however, test-takers’ voices on ethics are under-researched in the high school context of Iran. Hence, this study purported to disclose Iranian high school test-takers’ (n = 15) perceptions of the ethical requirements in CA. For this purpose, a systematic thematic coding approach (constant-comparative method) was used to analyze the participants’ perceptions. Findings yielded two overarching categories, including do no harm (e.g., establishing a supervision group, considering test-takers’ individual differences, keeping test results confidential, and turning back test sheets with feedback) and avoid score pollution (e.g., using additional knowledge sources, using alternative assessment methods, clarifying grading criteria, avoiding unfamiliar contents and surprise items). The findings refer to a local gloss on global principles of ethics, which is hoped to map out specific dimensions of this important notion for diverse assessment contexts (e.g., high-stakes language testing and CA) and stakeholder groups (e.g., high school teachers, assessment developers, and education officials).

Construction production trends and industry optimism in EU countries after the COVID-19 pandemic

The purpose of this study is to present the current changing situation of construction markets in selected European countries. Current trends in construction production are presented in relation to changes resulting from the coronavirus pandemic and other factors using the examples of France, the Netherlands, Belgium, Austria, Germany, Spain and Poland. The EU Construction Confidence Index (CCI) and data on the number of building permits issued in selected countries were used for inference. Additional sources of knowledge were publicly available information on ongoing and planned campaigns and government actions affecting local construction markets. The analysis presented shows a clear impact of the pandemic on construction production trends, an increase in optimism in the industry at its extinction and renewed declines in optimism due to the increasing destabilisation of economies as a result of inflation, rising energy prices and the war in Ukraine. Despite the difficulties, construction markets are slowly regaining their pre-pandemic growths, although the aforementioned factors are slowing them down. Strong mature economies, supported by additional government funding, will recover much faster than developing countries where uncertainty is greater. The negative indicators for Poland forecast a slowdown and a longer period of return to pre-pandemic COVID-19 growth.

Kebutuhan Air Irigasi pada D.I Krueng Pasee Aceh Utara

Water demand is the amount of water volume that must be met for irrigation, in the Krueng Pasee irrigation area of North Aceh has an irrigation network area of 5579 Ha. The purpose ofthis research is to obtain the maximum and minimum irrigation water demand discharge in the study area. This research can be an additional source of knowledge for writers in particular and for readers in general. As well as the results of this study can be known the value of rice planting water needs. The data used in the research is rainfall data sourced from BMKG (Meteorology, Climatology, and Geophysics Agency) Malikussaleh, used to calculate effective rainfall and climate data sourced from BMKGMalikussaleh in the form of temperature data, solar irradiation data, wind speed data and humidity or temperature data used to calculate evapotranspiration (ETo). ETo is a combination of evaporation and transpiration which is defined as the event of water loss from plant tissue and the surface of the soil usedas a place to grow plants. In analyzing ETo using the Penman Modification Methodology. The Penman method by adjusting the wind function according to local conditions produces the best approach to the evapotranspiration rate of the lysimeter results. The consumptive use of plants (ETc) during the land preparation period uses the results of the calculation of water requirements for land preparation (IR). Crop consumptive use (ETc) after land preparation is a calculation between evapotranspiration and cropcoefficient. The calculated irrigation water requirement (NFR) results in water requirement in the form of mm/day. Irrigation water requirements are converted to l/dt/ha with a conversion rate of 1/8.64. The smallest water demand calculation discharge was obtained in November-1 at Q = 4.32 m3/det and thelargest water demand in February -1 at Q = 13.40 m3/det. At the research location, rice planting begins in January-I, with a rice-soybean planting pattern. From the calculation of water demand, Krueng Pasee Irrigation Area has the smallest water demand in November-1 and the largest water demand in February-1.

Abstract P6-08-13: Home-based treatment with subcutaneous (SC) trastuzumab - only a pandemic solution? Real world evidence (RWE) analysis

Abstract Background The pandemic has accelerated the introduction of more flexible and cost-effective treatment forms. The efficacy of trastuzumab in the intravenous (IV) and SC forms is similar both in early and advanced HER2-positive breast cancer (BC) patients. Compared to IV administration, SC enables reduction of treatment costs and time, and saves equipment and human resources. SC formulation is more convenient for both patients and healthcare providers and may be implemented as a home-based therapy. Recently, systemic anticancer treatment (including chemotherapy) has been increasingly performed at home, improving patient comfort and reducing the burden on the healthcare system. Poland has already implemented home-based treatment with some biologic compounds; however, they have not included trastuzumab in BC patients. Objectives This RWE analysis aims to evaluate the organizational and therapeutic procedures related to the home-based treatment with SC trastuzumab and the attitudes of patients and healthcare providers to this approach. Material and methods The study enrolled early HER2(+) BC patients treated with trastuzumab during the COVID-19 pandemic. Monitoring and treatment duration were consistent with SmPC and reimbursement regulations in Poland. The first 3-6 doses of SC trastuzumab (alone or in combination with CHT) were administered at a cancer center in outpatient and inpatient settings. Subsequent doses were administered at home by 3 qualified breast nurses. Post-injection follow-up was used for educational purposes. Data were analyzed with descriptive statistics. The study was reviewed and approved by the local Bioethics Committee. Results The analysis included 20 patients treated in two comprehensive cancer centers in Poland with a median age of 59 years (range, 36-72 years). Seven patients (35%) were professionally active. The average distance from the place of residence to the cancer center was 24 km (range, 2-65 km). A total of 232 doses were administered (mean 11.6 doses per patient; range 6-14), 133 doses at home and 99 at the cancer center. The overall tolerance of trastuzumab was good and consistent with the known safety profile described in Summary of Product Characteristics. Only 1 patient (5%) discontinued treatment prematurely due to decreased LVEF; another 19 patients completed treatment as planned. For 19 patients (95%), the benefits of SC treatment included time savings, the ability to continue working, and avoiding crowded places and infection risk. 2 patients (10%) considered the nurse’s visit privacy disturbing, while 18 (90%) would recommend home-based drug administration. The average duration of a nurse’s stay at home was 60 minutes (range 30 to 130 minutes). No logistical or technical problems were reported, except for occasional patient lateness. Nurses positively assessed the treatment provided in the nursing office, which was a source of additional knowledge, and experience. The overall impression of home-based therapy was positive for both patients and nurses. The limitation of the study is the declarative nature of the data. Conclusions Home-based treatment with SC trastuzumab should be pursued due to its safety, ease of organization, positive perception by patients and nurses, and reducing healthcare system resources. It can be particularly valuable for disabled patients who have difficulty reaching the hospital and professionally active patients. Specialized, trained nurses can self-sufficiently carry out part of the prolonged trastuzumab treatment, reducing physician involvement. Citation Format: Barbara Radecka, Hudała-Klecha Joanna, Dariusz Sawka, Jolanta Sarga, Bożena Noworolska, Jolanta Sawicka, Elżbieta Duda, Natalia Obruśnik, Patryk Zając. Home-based treatment with subcutaneous (SC) trastuzumab - only a pandemic solution? Real world evidence (RWE) analysis [abstract]. In: Proceedings of the 2022 San Antonio Breast Cancer Symposium; 2022 Dec 6-10; San Antonio, TX. Philadelphia (PA): AACR; Cancer Res 2023;83(5 Suppl):Abstract nr P6-08-13.

Bestudering van gewysigde bewussynstate se moontlike bydrae tot die veld van kommunikasie

This explorative article is an attempt to focus attention on the paradigm shift in science that is occurring at present. The shift is the result of the clash between the traditional Western mechanistic approach and a more holistic world-view which also makes provision for direct, non-in tellectual experiences of reality. In the ordinary state of consciousness, for example, a person is ex pected to identify closely with his or her body image. In an altered state of consciousness (like deep medita tion) a person's identity can expand beyond the body image and encom pass other people or groups of people. Experiences of this kind can bring Instant intuitive knowledge that far exceeds the intellectual and educational background of the indi vidual. While identifying with an other person, one can gain access to that person's thoughts, feelings, physical sensations or memories. This holds implications for the com munication scientist. The possibility of viewing altered states of con sciousness as an additional source of Interpersonal communication knowledge and the implications of such additional knowledge for crea ting shared meaning are explored. It is proposed that the inclusion of al tered states of consciousness as a field of study, should be seriously considered by interpersonal com munication scientists

Benefits and challenges of using comics in foreign language teaching

At the present time there is a large variety of technologies for teaching foreign languages. Various methods and tools that facilitate the learning process and make it more productive. One of the reserves of intensifying the process of learning a foreign language are visualization tools. After all, in comics, as a rule, spoken language is used, dialogues are concise, and the information presented in the comics is emotionally colored, which contributes to its more effective absorption. The vocabulary encountered in comics, refers to a variety of areas of life and human activities, which allows you to use a comic almost in any lesson, only the right choice of lexical topics depends on the teacher. Note that educational comics can be used not only as an additional source of knowledge in a foreign language, but also for self-realization of students, for example, as a product of project-research activities. The aim of this article is to study the advantages and problems of using comics in teaching foreign languages. The object of the article is the process of the influence of comics on the student. The theoretical basis of the article is the scientific works of foreign and domestic researchers. Keywords: advantages, problems, comics, foreign language, visual method, teaching, principles.

RTX-KG2: a system for building a semantically standardized knowledge graph for translational biomedicine

BackgroundBiomedical translational science is increasingly using computational reasoning on repositories of structured knowledge (such as UMLS, SemMedDB, ChEMBL, Reactome, DrugBank, and SMPDB in order to facilitate discovery of new therapeutic targets and modalities. The NCATS Biomedical Data Translator project is working to federate autonomous reasoning agents and knowledge providers within a distributed system for answering translational questions. Within that project and the broader field, there is a need for a framework that can efficiently and reproducibly build an integrated, standards-compliant, and comprehensive biomedical knowledge graph that can be downloaded in standard serialized form or queried via a public application programming interface (API).ResultsTo create a knowledge provider system within the Translator project, we have developed RTX-KG2, an open-source software system for building—and hosting a web API for querying—a biomedical knowledge graph that uses an Extract-Transform-Load approach to integrate 70 knowledge sources (including the aforementioned core six sources) into a knowledge graph with provenance information including (where available) citations. The semantic layer and schema for RTX-KG2 follow the standard Biolink model to maximize interoperability. RTX-KG2 is currently being used by multiple Translator reasoning agents, both in its downloadable form and via its SmartAPI-registered interface. Serializations of RTX-KG2 are available for download in both the pre-canonicalized form and in canonicalized form (in which synonyms are merged). The current canonicalized version (KG2.7.3) of RTX-KG2 contains 6.4M nodes and 39.3M edges with a hierarchy of 77 relationship types from Biolink.ConclusionRTX-KG2 is the first knowledge graph that integrates UMLS, SemMedDB, ChEMBL, DrugBank, Reactome, SMPDB, and 64 additional knowledge sources within a knowledge graph that conforms to the Biolink standard for its semantic layer and schema. RTX-KG2 is publicly available for querying via its API at arax.rtx.ai/api/rtxkg2/v1.2/openapi.json. The code to build RTX-KG2 is publicly available at github:RTXteam/RTX-KG2.

Acute occupational exposures reported to the Dutch Poisons Information Center: a prospective study on the root causes of incidents at the workplace

BackgroundHazardous substances at the workplace can cause a wide variety of occupational incidents. This study aimed to investigate the nature and circumstances of acute occupational intoxications reported to the Dutch Poisons Information Center.MethodsDuring a one-year prospective study, data on the circumstances and causes of the incident, the exposure(s) and clinical course, were collected by a telephone survey with victims of an acute occupational intoxication.ResultsWe interviewed 310 patients. Most incidents occurred in industry (25%), building and installation industry (14%) and agriculture (10%). Patients were often exposed via multiple routes (ocular contact 40%, inhalation 34% and dermal contact 33%). Acids and alkalis were often involved. Exposure often occurred during cleaning activities (33%). The main root causes of these accidents were: technical factors such as damaged packaging (24%) and defective apparatus (10%), organizational factors such as lack of work instructions (44%) and poor communication or planning (31%), and personal factors such as disregarding work instructions (13%), not (adequately) using personal protective equipment (12%) and personal circumstances (50%) such as inaccuracy, time pressure or fatigue. The majority of the patients only reported mild health effects and recovered quickly (77% within 1 week).ConclusionsPoison Center data on occupational exposures provide an additional source of knowledge and an important basis for poisoning prevention strategies related to hazardous substances at the workplace. These data are useful in deciding which risk mitigation measures are most needed in preventing future workplace injuries.

Педагогическая риторика в обучении учителя и ученика

The article describes the experience of teaching pedagogical rhetoric as part of the subject of the culture of native Russian speech. The problem of the professional competence of the teacher of preschool and primary education in the field of speech activity is raised. The author briefly characterizes the history of the development of pedagogical rhetoric. A significant difference is emphasized in the quality of the language training of a teacher, educator and children, as well as ways to overcome this gap in the process of joint speech work. The styles and genres of speech inherent in the teacher as a carrier of the speech profession are characterized, methods and algorithms for their development are proposed. Additional sources of knowledge about listening and speaking as oral forms of speech of a teacher and a child, as well as speech samples from works of children's literature are named.

A Gnostic Understanding of Coping for the Cardiothoracic Surgeon.

A Gnostic Understanding of Coping for the Cardiothoracic Surgeon.

Педагогическая риторика в обучении учителя и ученика

The article describes the experience of teaching pedagogical rhetoric as part of the subject of the culture of native Russian speech. The problem of the professional competence of the teacher of preschool and primary education in the field of speech activity is raised. The author briefly characterizes the history of the development of pedagogical rhetoric. A significant difference is emphasized in the quality of the language training of a teacher, educator and children, as well as ways to overcome this gap in the process of joint speech work. The styles and genres of speech inherent in the teacher as a carrier of the speech profession are characterized, methods and algorithms for their development are proposed. Additional sources of knowledge about listening and speaking as oral forms of speech of a teacher and a child, as well as speech samples from works of children's literature are named.

In-depth insights into Alzheimer\u2019s disease by using explainable machine learning approach

Alzheimer’s disease is still a field of research with lots of open questions. The complexity of the disease prevents the early diagnosis before visible symptoms regarding the individual’s cognitive capabilities occur. This research presents an in-depth analysis of a huge data set encompassing medical, cognitive and lifestyle’s measurements from more than 12,000 individuals. Several hypothesis were established whose validity has been questioned considering the obtained results. The importance of appropriate experimental design is highly stressed in the research. Thus, a sequence of methods for handling missing data, redundancy, data imbalance, and correlation analysis have been applied for appropriate preprocessing of the data set, and consequently XGBoost model has been trained and evaluated with special attention to the hyperparameters tuning. The model was explained by using the Shapley values produced by the SHAP method. XGBoost produced a f1-score of 0.84 and as such is considered to be highly competitive among those published in the literature. This achievement, however, was not the main contribution of this paper. This research’s goal was to perform global and local interpretability of the intelligent model and derive valuable conclusions over the established hypothesis. Those methods led to a single scheme which presents either positive, or, negative influence of the values of each of the features whose importance has been confirmed by means of Shapley values. This scheme might be considered as additional source of knowledge for the physicians and other experts whose concern is the exact diagnosis of early stage of Alzheimer’s disease. The conclusions derived from the intelligent model’s data-driven interpretability confronted all the established hypotheses. This research clearly showed the importance of explainable Machine learning approach that opens the black box and clearly unveils the relationships among the features and the diagnoses.

The essence of activity-materiality-character on the space and scope of Osing house architecture

The phenomenon of a single architectural form has become a global problem. This is also observed in Indonesia as indicated by the specific traditional architecture known as Osing in Banyuwangi. Therefore, this study focuses on the issue of the essence of space created from the surrounding elements in Osing traditional architecture using a qualitative method which involved prioritizing new reading tools including the Lincourt phenomenological approach and the architectural anatomy of Salura. The results showed that the activity forms a linear circular pattern while the lower scoping elements form a geometric arrangement and have a linear movement direction. Moreover, the roof structure shows the dynamic quality of the elements which move from front to back. It was also discovered that the scope of the Osing space is a barrier with the activities within the house isolated and inwardly oriented. The use of local natural materials also provides a warm, rustic and simple character as well as a chance for sustainability. Furthermore, the structures and constructions show that the architecture prioritizes honesty and simplicity. This, therefore, means the essence of space in Osing architecture is in Jrumah based on the space which was found to be closed, natural, simple character, and prioritizing honesty. These findings are expected to be an additional source of knowledge on Osing architecture, serve as input for architects in designing modern houses in Banyuwangi, and input for policymakers in formulating a strategy to preserve this traditional architecture.

Whistleblowing in Health Care Organizations: A Comprehensive Literature Review

Purpose: To receive the answers to the following research problems: (1) How is the interest of researchers in whistleblowing in health care organizations developing? (2) How do researchers define whistleblowing in health care? (3) What are the main problems (limitations) of whistleblowing in health care organizations? (4) What factors affect whistleblowing in health care organizations? Design/methodology/approach: The method of systematic literature review based on the PRISMA model was used. To identify the factors affecting whistleblowing, McKinsey’s 7S framework was used. Findings: The researchers from the UK definitely dominate, and the papers from Central European countries seem to be invisible. The vast majority of works came from the 2010s. Whistleblowing serves the good and safety of the patient; however, there are staff concerns about the consequences they may face. ‘Style’, ‘staff’ and ‘shared values’ seem to be the most crucial for whistleblowing, and these are factors considered ‘soft’. Research limitations: The access to databases managed by the home University. In future studies, there is a need to take into account other databases, including additional sources of knowledge, like books and grey literature. Originality/implications: Identifying the state and place of research worldwide on whistleblowing in health care, and a proposal of the whistleblowing verification matrix. New definitions of whistleblowing and whistleblowers were proposed. The above may be considered theoretical contribution to science.

Evidence-based Methods in Rural Areas – Knowledge and National Guideline Utilization in Mental Health Service Development

ABSTRACT Purpose To examine how rural municipalities develop services to people with serious mental illness in relation to evidence-based practice and national guidelines. Additional sources of knowledge and strategies used by the municipalities in relation to their development needs were explored as well. Method Qualitative multiple-case approach, with 43 deep-interviews involving 84 informants representing selected social psychiatric services from 11 sites. Results National guidelines and evidence-based practices have a limited impact on how rural municipalities develop services to the target group. The municipalities favor other sources of knowledge, including regional networks, pragmatic problem-solving approaches and community-based knowledge. Discussion and conclusion Most of the informants expressed a need for more systematic and evidence-based knowledge in order to meet their clients’ needs. A major challenge to improve the utilization of these methods, is to make adaptions to match the rural municipalities’ needs and actual resources without risking the quality of these evidence-based services.

THE SOCIAL AND MORAL ATTITUDES OF CONVICTS AND THEIR PROACTIVITY USED AGAINST THE LIMITATIONS OF THE PRISON ENVIRONMENT

Th e concept of moral norms is an interdisciplinary issue, defi ned by diff erent fi elds of science. Attitudes towards the preferred moral norms are noticeably less frequent in both theoretical and empirical studies, although in the present study an attempt has been made to establish the relationships between the personal attitude of convicted persons towards fi ve independent moral norms and their proactive personality traits. Th e study involved 100 fi rst-time convicts and 100 recidivists, who were asked to respond to the statements made in Th e questionnaire on attitudes towards moral norms and Th e scale of proactivity in penitentiary isolation. Th e convicts were serving prison sentences in two diff erent penitentiary units in Poland. Th e results of the research showed that those convicted for the fi rst time who approved of attitudes towards vindictiveness, helping others and incitement to evil had a greater propensity for proactive behaviour. In addition, the group of recidivists showed no correlation between the declared attitudes to moral norms and their level of proactivity, but showed that they displayed more positive attitudes towards helping other people and vindictiveness, in comparison to the population of fi rst-time convicts. Th e results form an additional source of knowledge about the proactivity of convicts, which can be skilfully used, and therefore the research carried out is particularly important for penitentiary practitioners who carry out various rehabilitation activities, as well as specialists in executive criminal law.

Long-term effectiveness of an online decision aid for female cancer patients regarding fertility preservation: Knowledge, attitude, and decisional regret.

The decision, whether to undergo fertility preservation or not is highly demanding for cancer patients. Decision aids may act as an additional source of support. So far, only a limited number of decision aids regarding fertility preservation for female cancer patients exist and have been evaluated systematically. This paper presents the results of secondary analyses of the first randomized controlled trial evaluating an online decision aid for female cancer patients affected by different types of cancer. It focuses on fertility-related knowledge, attitude toward fertility preservation, and long-term effectiveness regarding decisional regret. Young female cancer patients between 18 and 40years of age were recruited after fertility counseling with a reproductive specialist. They were assigned to either the control group (counseling only) or the intervention group (counseling followed by the additional use of the decision aid). Both groups had to complete a questionnaire after counseling as well as 1 and 12months later, covering topics such as fertility-related knowledge, attitude towards fertility preservation, decisional conflict and regret. Recruitment was ongoing during 18months in eight fertility centers located in Switzerland and Germany. Mean age of participating women was 29.31years (SD 4.57). Of the entire sample (n=51) 53% were affected with breast cancer, 27.4% with lymphoma, and 19.6% with various other types of cancer. Knowledge regarding the most common fertility preservation methods was high and comparable in both groups. Positive attitude significantly exceeded negative attitude among all participants (p=0.001). Although the altogether low scores for decisional regret were on a higher level in the control group (T2: mean=19.00, SD=13.24; T3: mean=22.0, SD=20.67) than in the intervention group (T2: mean=14.12, SD=11.07; T3: mean=12.94, SD=13.24), there were no statistically significant differences between and within both groups. There was a positive association between decisional conflict and decisional regret at T3 (p=0.001, r=0.510). This decision aid was suitable as an additional source of knowledge and may positively impact decisional regret in the long term. Results suggest that the provision of an online decision aid as a complement to fertility counseling may facilitate decision-making.