Acrylate Research Articles

Effect of denture base acrylic resin containing silver nanoparticles on Candida Albicans adhesion and its release in artificial saliva

Background Candida albicans was considered a main reason of precipitate formations and decomposition of acrylic denture base; so many trials were objected to resist this microbial action and prolong the shelf life of the formulated fitting base. Aim of the work The present study aimed to adopt a new mixture of the silver nanoparticles with the PMMA denture base to get a prolonged antimicrobial protection for the formed base against Candida albicans. Statement of problem Accumulation of Candida Albicans on fitting surface of poly methyl meth-acrylate (PMMA) denture base. Purpose To evaluate the effect of denture base acrylic resin containing silver Nanoparticles (Ag NP) on Candida Albicans adhesion and its release in artificial saliva. Materials and methods Sixty round disks with dimensions of 15 mm diameter and 3 mm thickness specimens were prepared for this research. Control group A: 10 specimens were prepared from pure PMMA. Experimental group B: 50 specimens were prepared from PMMA containing 5% of Ag NP. Isolation and identification of Candida Albicans were taken from oral cavity of 10 patients by swabbing. The Specimens were immersed in artificial saliva for 3, 6, and 9 months. Microbiological test was done for specimens of each group to detect Candida Albicans accumulation at the same interval period by measuring the inhibition zone created around the disks. Specimens were taken from the artificial saliva to evaluate silver release in it by using UV-Vis Spectrophotometer Instrument ‘SHIMADZO UV-310 PC. For Spectrophotometer 1.0 cm and/or 0.2 cm matched silica cells. The amount of accumulated silver released was calculated to detect its cytotoxic effect1. Results For control group A there was no inhibition zone for Candida growth around the specimens. While for group B with Ag NP the greatest antimicrobial effect was found at zero time then was decreased gradually with increasing the time till reaching zero effect after 9 months resembling the control group. The amount of Nano silver in artificial saliva after 3 months was found to be little then it was increased gradually with increasing time. Conclusion Adding Ag NP to PMMA denture base has antimicrobial effect against Candida Albicans for only 9 months; then there was no effect as silver was released in saliva. The amount of released silver was found to be with no cytotoxic effect.

BUBBLE DEFECTS AND CONTROL OF THERMAL CURING OF WATERBORNE RESIN COATINGS

To solve the problem of bubble retention leading to a decrease in the performance of waterborne resin coatings during thermal curing, a rapid thermal curing coating based on an aqueous epoxy-modified acrylic resin containing an amino resin cross linker was synthesized through solution copolymerization. Using a synchronous thermal analyzer, the mass loss and heat flow during the thermal curing process of the coating was measured. In addition, an in situ thermal curing visualization system was used to observe the curing behavior at the easy-open end notches under different heating rates. The results indicated that the curing process is divided into an initial rapid heating stage and a subsequent slower heating stage by the boiling point of water, with a critical temperature range of 126-150°C. The visualization experiments showed that when the temperature reached 100°C, the water quickly evaporated to form bubbles. Increasing the heating rate before this temperature caused the bubbles to rapidly escape. Therefore, an optimal heating profile with a rapid initial heating rate of 3.13°C/s, followed by a slower heating rate of 0.52°C/s in the next stage, is proposed. This discovery is of great significance for optimizing the thermal curing process of waterborne coatings on metal substrates, including those used for easy-open ends.

Flexibly stretchable acrylic resin elastomer films for efficient electromagnetic shielding and photothermal conversion

A retractable, stretchable shielding device with large areal strain variability is essential for intelligent wearable electronics.

Effect of soft denture liners on complete denture treatments: A systematic review.

This systematic review examined the effectiveness of soft denture relining (SDR) materials. A comprehensive search of MEDLINE, Cochrane Library, and ICHUSHI was conducted up to July 26, 2020. Target outcomes were patient satisfaction, oral health-related quality of life (OHRQOL), masticatory ability (MA), denture functional duration, residual ridge resorption (RRR), and microbial contamination. An organization specializing in literature searches performed the reference searches, and two reviewers independently selected the literature sources, extracted the data, and assessed the risk of bias. The reviewers resolved any disagreements concerning the assortment of literature sources through discussion. SDR included acrylic- and silicone-based materials, which were evaluated separately. Reviewers selected 7, 5, 11, 1, 4, and 6 studies to assess patient satisfaction, OHRQOL, MA, functional duration, RRR, and microbial contamination, respectively. The results confirmed that SDR improved patient satisfaction, OHRQOL, MA, and RRR. However, the functional duration of SDR material is shorter than that of hard denture relining (HDR) or acrylic resin material. Furthermore, SDR material is more susceptible to microbial contamination in the long term. The risk of bias for the included studies tended to be high because of specific issues (difficulty in blinding SDR versus HDR). For patients who wear complete dentures, SDR often provides beneficial outcomes such as pain reduction and recovery from MA. However, caution should be exercised regarding their use owing to insufficient functional duration and the possibility of microbial contamination during long-term use.

Bond strength of metal brackets to enamel with a Russian adhesive complex: an in vitro study

The era of using adhesives to fix brackets began in the 70s of the last century. There are eight generations of foreign-made adhesive systems for the restoration of teeth. However, until now, in orthodontics, the development of domestic adhesive systems with improved properties of adhesion of brackets to tooth enamel still important, especially in the posterior teeth. The purpose of this work was to study the shear strength of fifth generation domestic adhesive between metal brackets and the enamel of molar teeth in laboratory conditions. The study included 17 specimens of extracted maxillary molars embedded in acrylic resin blocks. Brackets from G&H Orthodontics (G&H Wire Company, USA) were fixed to the tooth enamel using the domestic Compofix (ortho) set. The enamel was treated with etching gel (37% phosphoric acid) for 30 seconds. Then the gel was washed off with water and the surface of the enamel was thoroughly dried. A primer was applied to the prepared surface with an applicator, inflated with a weak air flow for 5-10 seconds and photopolymerized for 20 seconds. The surface of the bracket was treated with degreaser, then a thin layer of adhesive was applied, and the sample was fixed to the enamel. Excess material was removed with an applicator. The samples were photopolymerized for 20 sec. Then, the shear bond strength of the adhesive was determined according to the method of GOST 31574-2012 on a (Zwick/Roell Z010 testing machine, Zwick, Germany). The shear strength of the adhesive joint obtained during the test is 13.54±1.01 MPa, the average value of the index of adhesive residues on the surface of the bracket was 23%±4%, which corresponds to the standard average values according to GOST. The tested domestic adhesive system of the fifth generation can be recommended for the practical work of an orthodontist.

Evaluation of surface roughness, wettability and adhesion of multispecies biofilm on 3D-printed resins for the base and teeth of complete dentures.

This study evaluated the surface roughness, wettability and adhesion of multispecies biofilms (Candida albicans, Staphylococcus aureus and Streptococcus mutans) on 3D-printed resins for complete denture bases and teeth compared to conventional resins (heat-polymerized acrylic resin; artificial pre-fabricated teeth). Circular specimens (n=39; 6.0 mm Ø × 2.0 mm) of each group were subjected to roughness (n=30), wettability (n=30) and biofilm adhesion (n=9) tests. Three roughness measurements were taken by laser confocal microscopy and a mean value was calculated. Wettability was evaluated by the contact angle of sessile drop method, considering the mean of the three evaluations per specimen. In parallel, microorganism adhesion to resin surfaces was evaluated using a multispecies biofilm model. Microbial load was evaluated by determining the number of Colony Forming Units (CFU/mL) and by scanning electron microscopy (SEM). Data were subjected to the Wald test in a generalized linear model with multiple comparisons and Bonferroni adjustment, as well as two-way ANOVA (α=5%). The roughness of the conventional base resin (0.01±0.04) was lower than that of the conventional tooth (0.14±0.04) (p=0.023) and 3D-printed base (0.18±0.08) (p<0.001). For wettability, conventional resin (84.20±5.57) showed a higher contact angle than the 3D-printed resin (60.58±6.18) (p<0.001). Higher microbial loads of S. mutans (p=0.023) and S. aureus (p=0.010) were observed on the surface of the conventional resin (S. mutans: 5.48±1.55; S. aureus: 7.01±0.57) compared to the 3D-printed resin (S. mutans: 4.11±1.96; S. aureus: 6.42±0.78). The adhesion of C. albicans was not affected by surface characteristics. The conventional base resin showed less roughness than the conventional dental resin and the printed base resin. The 3D-printed resins for base and tooth showed less hydrophobicity and less adhesion of S. mutans and S. aureus than conventional resins.

Changes in the surface texture of pre-polymerized acrylic resin pediatric crowns following acidulated phosphate fluoride application.

This study aimed to investigate the effect of acidulated phosphate fluoride (APF) application on filler-free polymethyl methacrylate (PMMA)-based resin blocks for computer-aided design/computer-aided manufacturing (CAD-CAM), focusing on their use in pediatric crowns. Three types of PMMA-based blocks for CAD-CAM were evaluated, and a composite resin block for CAD-CAM was used as a control. Statistical analysis (p<0.05) of the data revealed that all PMMA-based blocks showed significantly higher gloss levels than the composite resin blocks. Two PMMA-based blocks also demonstrated significantly lower Ra and Sa values. SEM images showed no irregular changes in the surface properties of the PMMA-based blocks compared to those of the composite resin block. These results are significant in meeting the increasing demand for esthetic restorative treatments in pediatrics, where APF is commonly used for caries prevention. PMMA-based resin blocks for CAD-CAM are an effective alternative to prevent esthetic degradation from gloss reduction and plaque accumulation.

The antimicrobial activity of an antiseptic soap against Candida Albicans and Streptococcus Mutans single and dual-species biofilms on denture base and reline acrylic resins.

To evaluate the effect of antiseptic soap on single and dual-species biofilms of Candida albicans and Streptococcus mutans on denture base and reline resins. Samples of the resins were distributed into groups (n = 9) according to the prevention or disinfection protocols. In the prevention protocol, samples were immersed in the solutions (Lifebuoy, 0.5% sodium hypochlorite solution and PBS) for 7, 14 and 28 days before the single and dual-species biofilms formation. Overnight denture disinfection was simulated. In the disinfection protocol, samples were immersed in the same solutions during 8 hours after the single and dual-species biofilms formation. Antimicrobial activity was analyzed by counting colony-forming units (CFU/mL) and evaluating cell metabolism. Cell viability and protein components of the biofilm matrix were evaluated using confocal laser scanning microscopy (CLSM). Data were submitted to ANOVA, followed by Tukey's post-test (α = 0.05) or Dunnett's T3 multiple comparisons test. In the prevention protocol, Lifebuoy solution effectively reduced the number of CFU/mL of both species. In addition, the solution decreased the cell metabolism of the microorganisms. Regarding disinfection protocol, the Lifebuoy solution was able of reduce approximately of 2-3 logs for all the biofilms on the denture base and reline resin. Cellular metabolism was also reduced. The images obtained with CLSM corroborate these results. Lifebuoy solution was effective in reducing single and dual-species biofilms on denture base and reline resins.

Flexural strength of repaired denture base materials manufactured for the CAD-CAM technique.

To evaluate the flexural properties of repaired poly(methylmethacrylate) (PMMA) denture base materials for computer-aided design/computer-aided manufacturing (CAD-CAM) and to compare them with heat-activated polymerized PMMA. A total of 288 specimens (65 × 10 × 2.5 mm) were prepared using both CAD-CAM and conventional blocks and repaired using autopolymerizing and visible-light polymerizing (VLC) materials. Microwave energy, water storage and hydroflask polymerization were applied as additional post-polymerization cycles after the repair process. The flexural strength (FS) of the specimens was evaluated using the three-point bending test. Data were evaluated statistically using 2-way ANOVA followed by Bonferroni's correction to determine the significance of differences between the groups (P ≤ 0.05). The FS of the denture base materials for CAD-CAM was significantly higher than that for the heat-activated group (P ≤ 0.05). The FS was significantly highest when microwave energy was used for the post-polymerization cycle. The FS values for all groups repaired with VLC resin were significantly lower than for the autopolymerization group (P ≤ 0.05). The flexural properties of denture base materials for CAD-CAM repaired using autopolymerizing acrylic resins can recover by 50-70%. Additional post-polymerization cycles for autopolymerizing repair resin can be suggested to improve the clinical service properties of repaired dentures.

Effect of Different Degrees of lingual Implant Inclination on the Retention of Locator Retained Mandibular Implant Overdenture. An In-Vitro Study

Purpose: This study was condacted to evaluate and compare different degrees of lingual implant inclination on retention of locator attachments used for two implant retained mandibular overdentures .Materials and Methods: Four acrylic resin models representing acompletely edentulous mandibular ridges were used. Each model received two implants inserted at canine area bilaterally with different degree of lingual inclination. Group I (control Group) 00, Group II (100), Group III (200), and Group IV (300). The residual ridge and the retromlar regions for each acrylic resin model were covered by auto-polymerized silicon material to simulate the oral mucosa. Four experimental acrylic metal reinforced overdenture were fabricated and connected to the implants using Locator attachments, Universal Testing Machine was used for measuring initial and final retentive force, The Results: Locator transparent, 00 inclination and anterior dislodging recorded the highest retentive forces, while Locator blue 100 inclination and vertical dislodging recorded the lowest retention values. Conclusions: For majority of groups, inserts, dislodging forces, initial retention recorded significant higher values than final retention.

Impact of Artificial Aging on the Physical and Mechanical Characteristics of Denture Base Materials Fabricated via 3D Printing.

Three-dimensional (3D) printing is becoming more prevalent in the dental sector due to its potential to save time for dental practitioners, streamline fabrication processes, enhance precision and consistency in fabricating prosthetic models, and offer cost-effective solutions. However, the effect of aging in artificial saliva of this type of material has not been explored. To assess the physical and mechanical properties of the two types of 3D-printed materials before and after being subjected to artificial saliva, a total of 219 acrylic resin specimens were produced. These specimens were made with two types of 3D-printed materials, namely, NextDent (ND) and Formlabs (FLs), and a Schottlander heat-cured (HC) resin material that was used as a control. Water sorption and solubility specimens (n = 5) were tested after three months of storage in artificial saliva. Moreover, the Vickers hardness, Martens hardness, flexural strength/modulus, and impact strength were evaluated both under dry conditions and after three months of storage in artificial saliva. The degree of conversion (DC), elemental analysis, and filler content were also investigated. The ANOVA showed that 3D-printed resins had significantly greater sorption than the control group (p < 0.05). However, the flexural strength values of the 3D-printed materials were significantly greater (p < 0.05) than those of the heat-cured material. The DC of the 3D-printed resins was lower than that of the control group, but the difference was not significant (p > 0.05). The 3D-printed materials contained significantly more filler than the control (p < 0.05). Moreover, the artificial saliva had a significant effect on the Vickers hardness for all tested groups and on the Martens hardness for the control group only (p < 0.05). Compared with conventional heat-cured materials, 3D-printed denture base materials demonstrated relatively poorer performance in terms of sorption, solubility, and DC but exhibited either comparable or superior mechanical properties. The aging process also influenced the Vickers and Martens' hardness. The strength of the 3D-printed materials was in compliance with ISO recommendations, and the materials could be used alongside conventional heat-cured materials.

EVALUATION OF BOND STRENGTH BETWEEN DIFFERENT SYSTEMS FOR ADHESIVE CEMENTATION TO FELDSPATHIC PORCELAIN AND ZIRCONIUM OXIDE

Introduction: New systems for adhesive cementation have been increasingly developed and used in daily clinical practice for the cementation of ceramic prostheses. Differences in the chemical composition of various system components can influence the bond strength between the resin cement and the ceramic. Objective: This study aims to evaluate the bond strength between two ceramic systems—feldspathic porcelain and yttria-stabilized zirconium oxide—and three different systems for adhesive cementation: Rely X ARC, Multilink System, and Rely X UCem. Methodology: Thirty discs of Noritake feldspathic porcelain and thirty discs of zirconium oxide ceramic were fabricated, each measuring 7.5 mm in diameter by 3.0 mm in thickness, according to the manufacturers’ instructions. The discs were polished on a mechanical polisher with water sandpaper ranging from 320 to 1500 grit and embedded in ½ inch PVC tubes with self-curing acrylic resin. The feldspathic porcelain discs were conditioned with 10% hydrofluoric acid for 120 seconds, and the zirconium oxide discs were sandblasted with 40 psi alumina for 10 seconds at 10 mm. All discs were then washed and placed in an ultrasonic bath with distilled water for 10 minutes. The cementation systems were applied according to the manufacturers’ instructions (n=10) on an adhesion area of 5.0 mm in diameter, delimited by a tripartite metal matrix. The samples underwent 1,000 thermal cycles ranging from 5°C to 55°C. Shear bond strength tests were performed on an EMIC DL2000 testing machine with a 20 kN load cell and a speed of 0.5 mm/min. The mean values of the groups were as follows (in MPa): Feldspathic with Rely X ARC (G1) 6.21; Feldspathic with Multilink (G2) 8.98; Feldspathic with Rely X UCem (G3) 8.15; Zirconium Oxide with Rely X ARC (G4) 0.53; Zirconium Oxide with Multilink (G5) 9.25; Zirconium Oxide with Rely X UCem (G6) 4.37. Data were subjected to one-way ANOVA and Tukey tests. Results: There was no significant difference among the feldspathic porcelain groups. For zirconium oxide, Multilink showed higher bond strength values. Conclusion: The bond strength between the cements and feldspathic porcelain exceeded the intrinsic strength of this material, and Multilink showed the highest bond strength values regardless of the ceramic material.

A Novel Technique for Characterization of Ocular Prosthesis by Utilizing Ceramic Stains and Composite Glaze

Since ancient times eyes are known to be lsquowindows to the soulrsquo. Loss of an eye can have crippling effect on the appearance as well as the psychology of an individual. An ocular prosthesis both stock and custom-made enhances the esthetics by artificially replacing bulb of the eye. Various techniques have been described in literature to customize an ocular prosthesis and enhance its appearance to closely match the natural eye of the patient. Symmetry and characterization are critical for esthetic appearance of an ocular prosthesis. This case report describes a novel technique for characterization of an acrylic resin ocular prosthesis using ceramic stains mixed with an external glaze. The prime purpose of the rendered treatment plan was to restore the lost ocular structure considering the patientrsquos esthetic demands. The final outcome of the prosthesis fabricated using this technique validates the use of composite glaze as a simple yet a predictable and economical laboratory technique.

Strategies based on nido-carborane embedded indole fluorescent polymers: their synthesis, spectral properties and cell imaging studies.

The continuous preparation scheme EPO-Poly-indol-nido-carborane (E-P-INDOLCAB), L100-55-Poly-indol-nido-carborane (L-P-INDOLCAB), RS-Poly-indol-nido-carborane (S-P-INDOLCAB), and RL-Poly-indol-nido-carborane (R-P-INDOLCAB) were used to prepare the four types of acrylic resin-coated nido-carborane indole fluorescent polymers. After testing their spectral properties and the fluorescence stability curve trend at various acidic pH values (3.4 and 5.5, respectively), L-P-INDOLCAB and S-P-INDOLCAB were determined to be the best polymers. The stable states of the two polymers and the dispersion of the nanoparticles on the system's surface during Atomic Force Microscope (AFM) test are shown by the zeta potentials of -23 and -42mV. The dispersion of nanoparticles on the system's surface and the stable condition of the two polymers were examined using zeta potential and atomic force microscopy (AFM). Transmission electron microscopy (TEM) can also confirm these findings, showing that the acrylic resin securely encases the interior to form an eyeball. Both polymers' biocompatibility with HELA cells was enhanced in cell imaging, closely enclosing the target cells. The two complexes displayed strong inhibitory effects on PC-3 and HeLa cells when the concentration was 20ug/mL, as validated by subsequent cell proliferation toxicity studies.

Filling ability of ready-to-use or powder-liquid calcium silicate-based sealers after ultrasonic agitation.

This study evaluated the effect of ultrasonic agitation on the filling capacity of ready-to-use calcium silicate-based sealer Bio-C Sealer (BCS, Angelus, Paraná, Brazil) or powder-liquid BioRoot RCS (BR, Septodont, Saint-Maur-des-Fossés, France) using curved artificial canals by micro-computed tomography (micro-CT). Additionally, flow (mm) and flow area (mm2) were evaluated for both materials. Acrylic resin main canal (60° curvature and 5 mm radius, with 3 lateral canals in the cervical, middle, and apical thirds) were prepared up to size 40/.05 (Prodesign Logic, Brazil). The agitation method was used with ultrasonic tip (US, Irrisonic, Helse, Brazil): BCS, BCS/US, BR, and BR/US. All specimens were filled using the single-cone technique. The samples were scanned by micro-CT (8,74 µm) after obturation. The percentage of filling material and voids were calculated. Flow was evaluated based on ISO 6876/2012 standards (mm) and area (mm2). The data were statistically analyzed using ANOVA and Tukey tests (α = 0.05). BR/US showed lower percentage of filling material in the lateral canals than and, BCS/US (p<0.05). BR/US resulted in a higher percentage of voids than BR in the lateral apical third (p<0.05). BCS showed higher flow than BR (p<0.05). BCS and BR presented proper filling capacity in the simulated curved canals regardless of the use of ultrasonic agitation. However, BR/US showed more voids in the apical third. BCS demonstrates higher filling ability.

Synthesis and application of sustainable vegetable oil-based polymers in 3D printing

Chemical modifications of vegetable oil and their 3D printing applications are discussed. Acrylate resin compatibility with 3D printing methods are presented. 3D printed products using vegetable oil-derived materials, providing insights into future opportunities are explored.

Recent Reviews on Hybrid Nano Reinforcements for Improving Mechanical Properties of Polymers for sustainable applications

The paper reviews the impact of hybrid nano particles in polymers that would enhance the mechanical properties. Various nano fillers have been used as reinforcements that would improve the mechanical properties of the composite materials. Poly methly methacrylate (PMMA) is preferred as the matrix material especially in denture bases as it overcomes the deficiencies that the other materials show. (PMMA) is an acrylic resin commonly used with a long heritage for prosthetic reasons. It can be classed as chemically or thermally polymerized material based on the causes that trigger the reaction. The nano fillers when used as reinforcements in PMMA have shown very good results. The microstructure behavior of the distribution of the nanofillers were studied through XRD, SEM, AFM and other techniques. Some studies have used optimization techniques to compare the results.

Surface Roughness and Weight Loss of Heat Cure and Self-Cure Acrylic Resins Which Were Subjected to Tooth Brush and Tooth Paste Cleaning-an In Vitro Study

Surface Roughness and Weight Loss of Heat Cure and Self-Cure Acrylic Resins Which Were Subjected to Tooth Brush and Tooth Paste Cleaning-an In Vitro Study

Effect of Surface Treatments with Plasma and Chemical Bond on Shear Bond Strength of Acrylic Denture Teeth to Flexible and Heat-Cured Denture Base Material: An In Vitro Study

Introduction: We aimed to evaluate the shear bond strength of acrylic denture teeth to flexible and heat-cured denture base material after surface treatments with argon plasma, chemical bonding agent (PALFIQUE universal), and combination. Methods: A total of 80 incisor acrylic denture teeth were treated with a argonplasma, chemical bond (PALFIQUE universal bond), and a combination with 10 samples for each group. The neck (gingival portion) of teeth was cut at a 45° angle, and the teeth were attached to heat-cured acrylic resin and flexible denture base material. All the specimens were stored in artificial saliva for 7 days in an incubator (37 °C). A shear bond strength test was conducted using an Instron universal testing machine. Data were analyzed by the analysis of variance (ANOVA) and the Tukey’s honest significant difference post hoc test using R 4.2.3. Results: A statistically significant difference was found among study groups regarding the type of base, surface treatment with bond, plasma, and combination of bond and plasma (P &lt; 0.00). The Tukey’s test showed that in a heat-cured base, the difference between the control and surface treatment with bond was not significant (P &gt; 0.05). Also, in the flexible base group, the difference between the control and surface treatment with plasma was not significant (P = 0.162). Conclusion: In heat-cured denture-base group, the shear bond strength increased significantly with the combination of surface treatment with argon plasma and a chemical bonding agent (PALFIQUE universal). In the flexible denture-base group, the shear bond strength increased significantly with use of a surface treatment with a chemical bonding agent (PALFIQUE universal).

Effectiveness of experimental dentifrices based on essential oils on biofilm on complete dentures: an in vitro study.

To conduct an in vitro evaluation of experimental dentifrices containing essential oils of Bowdichia virgilioides Kunth (BvK), Copaifera officinalis (Co), Eucalyptus citriodora (Ec), Melaleuca alternifolia (Ma) and Pinus strobus (Ps) at 1%. The variables evaluated were organoleptic and physicochemical characteristics, abrasiveness (mechanical brushing machine) simulating 2.5 years, and microbial load (Colony Forming Units - CFU/mL), metabolic activity (XTT assay) and cell viability (Live/Dead® BacLight™ kit) of the multispecies biofilm (Streptococcus mutans: Sm, Staphylococcus aureus: Sa, Candida albicans: Ca and Candida glabrata: Cg). Specimens of heat-polymerized acrylic resins (n=256) (n=96 specimens for abrasiveness, n=72 for microbial load count, n=72 for biofilm metabolic activity, n=16 for cell viability and total biofilm quantification) with formed biofilm were divided into eight groups for manual brushing (20 seconds) with a dental brush and distilled water (NC: negative control), Trihydral (PC: positive control), placebo (Pl), BvK, Co, Ec, Ma or Ps. After brushing, the specimens were washed with PBS and immersed in Letheen Broth medium, and the suspension was sown in solid specific medium. The organoleptic characteristics were presented by descriptive analysis. The values of density, pH, consistency and viscosity were presented in a table. The data were analyzed with the Wald test in a generalized linear model, followed by the Kruskal-Wallis test, Dunn's test (mass change) and the Bonferroni test (UFC and XTT). The Wald test in Generalized Estimating Equations and the Bonferroni test were used to analyze cell viability. All dentifrices showed stable organoleptic characteristics and adequate physicochemical properties. CN, Ec, Ps, Pl and PC showed low abrasiveness. There was a significant difference between the groups (p<0.001) for microbial load, metabolic activity and biofilm viability. It was concluded that the BvK, Ec and Ps dentifrices are useful for cleaning complete dentures, as they have antimicrobial activity against biofilm. The dentifrices containing Bowdichia virgilioides Kunth showed medium abrasiveness and should be used with caution.