IT is becoming generally accepted that many cutaneous abnormalities are symptomatic of general diseases and, therefore, that a disease may have in common various manifestations detectable in various organs of the body. However, there are many severe generalized and universal eruptions, some of which terminate fatally, such as pemphigus, which in the present state of knowledge appears to be entirely of cutaneous origin with no apparent organic abnormalities of other organs. The presence of cutaneous changes in systemic diseases has been particularly emphasized in recent years with the discovery of new findings in collagen diseases. The work of Libman and . . .
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