Total Abdominal Hysterectomy Research Articles

Optimizing Hysterectomy: A Prospective Comparative Analysis of Surgical Techniques and Their Impact on Women's Lives.

To investigate diverse hysterectomy techniques to determine their influence on patient outcomes, including pain levels, sexual function, anxiety, and quality of life. Of particular focus is the comparison between vessel sealing and traditional suturing in abdominal, vaginal, and laparoscopic hysterectomies. This study is unique in its comprehensive evaluation, considering patient satisfaction, recommendation rates, recovery times, and various other aspects. Our prospective cohort study adhered to ethical guidelines, involving a meticulous assessment of patients, including medical history, anxiety levels, pelvic pain, sexual function, and quality of life. Surgical methods were explained to patients, allowing them to actively participate in the decision-making process. Sociodemographic information was collected, and exclusion criteria were applied. Hysterectomy methods included total abdominal hysterectomy (TAH), laparoscopic hysterectomy (TLH), vaginal hysterectomy (VH), and a modified vaginal technique known as VH Mujas. Several parameters were recorded, including operation indications, uterine volume, hospital stay, operation duration, pre-operative and post-operative complications, and more. In all groups, a statistically significant increase was found in pre-operative-post-operative FSFI sexual function values (p < 0.001). The patient's basal Beck Anxiety Scale scores significantly decreased following the decision for vaginal surgery, both in the VH and VH Mujas groups (p < 0.05). However, Beck Anxiety Scale scores at patients' initial assessments significantly increased following the decision for abdominal and laparoscopic surgery (p < 0.001). According to the results of the SF-36 quality of life assessment, an increase was observed in all post-operative quality of life parameters in patients who underwent surgery with different methods due to VH (p < 0.05). Our comprehensive comparison of hysterectomy techniques demonstrated that VH, particularly when utilizing the Mujas technique, outperforms other hysterectomy methods regarding patient safety and post-operative satisfaction but also offers the benefit of minimal invasiveness. Notably, this is reflected in improved quality of life, enhanced sexual function, lower pain scores, and favorable cosmetic results. The success of a hysterectomy procedure depends on precise indications, surgical planning, proper patient selection, and effective communication. This study emphasizes the significance of these factors in achieving optimal outcomes. The development of specialized vascular closure devices can further enhance the feasibility of vaginal hysterectomy, making it a preferable choice in gynecological surgery. The study contributes valuable insights into selecting the most suitable hysterectomy method for patients and optimizing their recovery.

Metastasis of Clear Cell Renal Cell Carcinoma to Uterine Leiomyoma: First Case Report and Review of Literature.

Metastasis of clear cell renal cell carcinoma (clear cell RCC) to the gynecologic tract is infrequent, and involvement of the uterus is extremely rare. A review of the literature identified a total of 12 reported examples with metastasis to the uterine serosa (1), endometrium (5), cervix (5) and only one with metastasis to the myometrium. This report represents the first case of tumor-to-tumor metastasis involving a clear cell RCC with metastasis to a uterine leiomyoma. The patient was a 50-year-old woman status post-radical nephrectomy for newly diagnosed unilateral clear cell RCC (stage pT3a) with negative margins, who subsequently underwent a total abdominal hysterectomy and bilateral salpingo-oophorectomy for the incidental finding of multiple uterine masses measuring up to 14.5 cm suggestive of fibroid on pelvic ultrasound. The pathologic exam of the specimen was consistent with metastatic clear cell RCC (1.2 cm) to uterine leiomyoma, confirmed with keratin, vimentin, CD10, CA9, and PAX8 immunohistochemistry. The patient's postoperative course was uneventful, and no new lesions were identified at follow-up during the past 6 months.

Cistoadenoma mucinoso gigante de ovario

Although ovarian mucinous cystadenoma has a benign growth, it can grow to be very large. We present the case of a 70-year-old patient who came to the clinic for recurrent and diffuse abdominal pain. On physical examination, a large mass was palpated that occupied the entire abdominal cavity, up to the xiphoid appendix, rounded, retentive, with defined edges, non- painful, non-movable. Presence of edema in lower limbs. During the surgical act, a myomatous uterus and a giant left ovarian cyst measuring approximately 40 x3 0 cm and weighing 13.6 kg were identified. Total abdominal hysterectomy and bilateral salpingo-oophorectomy were performed. The biopsy confirmed the diagnosis of benign ovarian mucinous cystadenoma and uterine leiomyomatosis. The postoperative period progressed favorably. The incidence of giant ovarian cystadenoma is relatively unknown due to the lack of a standardized concept and currently available advanced imaging modalities. Keywords: Ovary, Ovarian cysts, Mucinous cystadenoma, Ovarian neoplasms.

Replacement of Total Abdominal Hysterectomy by TLH in a Patient with Previous Pelvic Surgery

Background: In a patient who had previous pelvic surgery, total laparoscopic hysterectomy (TLH) has well-established advantages over total abdominal hysterectomy. The hysterectomy is a common gynaecological operation. Although the vaginal route is preferred for hysterectomy, the best route for women who are not candidates for the vaginal approach is unknown. Hysterectomies are increasingly being performed laparoscopically as technology advances and experience grows. Objectives: The aim of this study is to evaluate the replacement of total abdominal hysterectomy by TLH in a patient with previous pelvic surgery. Method: This observational study was carried out on 60 women admitted in the Department of obstetrics and gynaecology, Labaid specialized Hospital, Dhaka, Bangladesh during the study period. The duration of the period was from July 2021 to June 2022. The data for this study about had been accumulated from patients sociodemographic &amp; obstetrics information, physical examination and per-operative findings. Statistical evaluation of the results used to be got via the use of a window-based computer software program devised with Statistical Packages for Social Sciences (SPSS-24). Results: A total of 60 patients were included in final analysis. According to the study population's age distribution of the study population, it was observed that 15(25.0%) were in group 35-38, 23(38.33%) were in group 39-42, 16(26.66%) were in group 43-46 and 6(10.0%) were in group 47-50. according to patient demographics, it was observed that 44(73.33%) were Leiomyoma, 29(48.33%) were Bleeding, 3(5.0%) were Pelvic pressure, 19(31.66) were Pelvic pain and 15(0%) were size growth. Conclusion: TLH for endometrial pathology has few problems and is well tolerated by a restricted group of patients. For suitable patients, the benefits include decreased blood loss and a shorter hospital stay. TLH can be performed effectively despite previous abdominal surgery. Patients who had previous .......

Malignant melanoma arising in mature teratoma with pugnacious spread: A case report

Of all ovarian neoplasms, mature cystic teratomas make up between 10–20%. Malignant transformation accounts for just 0.1-2 percent of cases of adult teratoma. Malignant melanoma is one of the rarest metamorphoses. Here, we describe a postmenopausal woman who complained of abdominal pain. Upon examination, it was discovered that she had an abdominally metastasized mature dermoid cyst that had ruptured. Following an exploratory laparotomy and staging procedures, she had a total abdominal hysterectomy and bilateral salpingo-oophorectomy with removal of melanotic deposits from the pouch of doughlas, bladder peritoneum, mesentric, and omentum, as well as the small and large bowel serosa. Only roughly 45 cases of malignant melanoma originating in mature cystic teratomas in the ovary have been documented since 1901.

A case series on live ectopic pregnancy

A pregnancy which develops outside uterus is called ectopic pregnancy that comprises nearly two percent of total pregnancies. In first case a 25years old female presented with lower abdominal pain and bleeding per vagina with 3 months of amenorrhea and history of irregular oral contraceptive pill use. A live ectopic pregnancy of 12 weeks 3 days gestation found on right fallopian tube during laparotomy and right salpingectomy was done. In second case, a third gravida mother presented with bleeding per vagina and lower abdominal pain with history of 2.5 months of amenorrhea and chronic pelvic inflammatory disease. During laparotomy, both sided hydrosalpinx and left sided live ectopic pregnancy found on the distal end of fallopian tube and left salpingectomy with fimbriectomy with right sided tubal ligation was done. In third case, a third gravida mother with history of lower uterine caesarean section and ruptured left sided tubal ectopic pregnancy previously, presented with lower abdominal pain with 2 months of amenorrhea. Ultrasonography diagnosed a live right sided cornual ectopic pregnancy of 6weeks 6days and conservative management with injection methotrexate was started. Later due to sudden hemodynamic instability, emergency laparotomy was done and ruptured right cornual ectopic pregnancy was found and treated with total abdominal hysterectomy. All these cases were managed successfully. This case series emphasizes that early serological and sonographic diagnosis of location of pregnancy is necessary, there should be high suspicion for ectopic pregnancy even beyond the first trimester and the decision of conservative management in early ectopic pregnancy should be taken judiciously after checking all parameters of the patient.

Bladder endometriosis – diagnostic and management challenges: A case report

Background: Urinary tract endometriosis (UTE) is the presence of endometriotic implants in the bladder,ureter, kidneys, or urethra. It affects ~1% of women with endometriosis and occurs more commonlyamong those with deep infiltrative endometriosis. Bladder endometriosis is the most commonpresentation, comprising 85% of cases. Concomitant involvement of the bladder and ureter is rare,comprising 1.4% of all cases. The clinical presentation involves lower urinary tract symptoms, thatworsen during menses. Timely diagnosis and treatment are crucial in ameliorating symptoms andpreventing complications, such as obstructive nephropathy. This is a case of bladder endometriosis withureteral involvement, outlining management challenges, reviewing evidence on managementapproaches, and highlighting the experience gained from this case in managing complex UTE.Case presentation: A 38-year-old female presented with a longstanding history of pelvic pain, dysuria,and new-onset voiding difficulty. She had undergone two prior surgical procedures for endometriosis,including a total abdominal hysterectomy. Her physical examination was normal. Ultrasound revealed a3-cm intracavitary bladder mass, which was described as likely endometriosis on magnetic resonanceimaging. On cystoscopy the mass was noted to be larger, encasing the left ureteric meatus. Alaparoscopic cystostomy was performed, with partial resection of the mass and placement of a temporaryureteric stent. After three months of medical treatment with dienogest, cystoscopy revealed a significantreduction in size with sub-centimeter residual avascular tissue. This was resected avoiding the ureter andureteric meatus. A new ureteric stent was placed. A repeat cystoscopy three months later revealed goodhealing with no residual endometriosis. The stent was removed, and a retrograde pyelogram confirmedno meatal stenosis or ureteric obstruction. She has remained symptom-free.Conclusion: Medical and surgical options are available for bladder endometriosis, with partialcystectomy being the gold standard. The initial approach is dependent on the size of the lesion and theextent of ureteric involvement. A staged approach that combines medical or surgical management canensure optimal outcomes while reducing surgery-associated morbidity in complex cases.

COMPARISON OF EPIDURAL VOLUME EXTENSION USING 2% LIGNOCAINE WITH STANDARD EPIDURAL VOLUME EXTENSION TECHNIQUE FOR HYSTERECTOMY UNDER COMBINED SPINAL EPIDURAL ANESTHESIA

Objectives: We compared epidural volume extension (EVE) using 2% Xylocaine with standard EVE technique and studied characteristics of neuraxial block along with hemodynamic stability and recovery profile in total abdominal hysterectomy surgery under combined spinal-epidural (CSE) anesthesia. Methods: 50 patients undergoing hysterectomy were randomly assigned into two groups. Group M (EVE with 2% 10 mL lignocaine) and Group C (EVE with 10 mL NS). Patients were anesthetized using CSE with 0.75% hyperbaric ropivacaine 2.5 mL and EVE, as per drug assigned to group. Anesthesia was maintained with epidural top-up with 2% lignocaine in 6 mL aliquot. Conscious sedation was provided. Perioperative data and recovery profile were recorded. Results: The amount of epidural anesthesia required to maintain block was less in Group M (17.7±4.5 mL in comparison to 26.9±7.3 mL in Group C p&lt;0.001). Time for first epidural top-up required was early in Group C (62.1±26.2 min) than in Group M (83.718±.3 min). Onset of motor blockade was earlier in Group M (8.4±4.8 min). Quality of anesthesia was better in Group M. Pain and recovery from neuraxial block was earlier in Group C (31.02±13 min) in comparison to 49.88±12.01 min in Group M. Safe level of block was achieved without affecting cardiorespiratory function in all patients. Conclusion: CSE with modified EVE is a feasible technique, is associated with early onset of neuraxial block, and had longer time of two-segment regression with the need of less anesthesia drugs.

Colouterine fistula relating to diverticulitis: a rare clinical entity

Abstract Colouterine fistula is a rare but recognizable complication of diverticulitis. This case illustrates the presence of a colouterine fistula in an elderly patient who had an atypical presentation for diverticulitis. She was initially treated with intravenous antibiotics for diverticulitis with a contained abscess. This gave her an opportunity to avoid surgery. However, her sepsis failed to respond to the initial treatment. Progress computerized tomography imaging demonstrated the presence of a colouterine fistula for which she required source control. Thus she underwent laparotomy, Hartmann’s procedure, and total abdominal hysterectomy with bilateral salpingo-oophorectomy. The diagnosis of colouterine fistula was confirmed intraoperatively and on histopathology. Subsequently, the patient had an uneventful recovery following the operation. This case highlights the rarity but also the veracity of this clinical entity.

Giant endometrial polyp in a post-menopausal woman: a rare case report from Nepal

Introduction: Endometrial polyps (EPs) result from the overgrowth of endometrial glands and stroma. Giant endometrial polyps, defined as those exceeding 4 cm, are rare, and their association with phytoestrogen (PE) intake is infrequently reported. Case presentation: The authors present a case of a giant endometrial polyp in a 59-year-old post-menopausal woman from Nepal. The patient presented with lower abdominal pain and a history of vaginal spotting. She was not under any drugs or medications, including hormones, but had a regular intake of PE-rich foods. Imaging revealed a giant endometrial polyp and a uterine fibroid. Total abdominal hysterectomy and bilateral salpingo-oophorectomy (TAH-BSO) were performed and histopathology examination confirmed the diagnosis of endometrial polyp and fibroid. Discussion: In our case, the patient’s increased age and PE-rich diet were identified as potential risk factors for the giant endometrial polyp. Giant endometrial polyps are rare, with limited cases reported to date, often associated with tamoxifen or raloxifene use. Phytoestrogens can exhibit oestrogenic effects, contributing to endometrial polyps. This case emphasizes the importance of further research to explain the relationship between phytoestrogen intake and giant endometrial polyps. Conclusion: Giant endometrial polyps are uncommon, and their association with phytoestrogen intake remains underexplored. Clinicians should consider dietary factors in history while evaluating endometrial polyps, and further research is necessary to explore the potential role of phytoestrogens in the development of giant endometrial polyps.

Measuring uterine cavity volume with sonohysterography: A new objective method.

The uterine cavity is a potential space with limited methods for evaluating its volume, limiting the evaluation of interventions' effectiveness in various uterine conditions. This study aims to objectively measure the uterine cavity volume using sonohysterography coupled with a Foley catheter to provide a normative model of age and parity-related uterine cavity volume. The research included 35 women (group 1) with a total abdominal hysterectomy and 150 women (group 2) who underwent sonohysterography for various gynecologic indications. Saline infusion sonography was administered to all patients. The most common shape obtained after the saline infusion was taken to measure the uterine cavity's dimensions and volume. The uterine cavity volumes, as measured by sonohysterography, and the volumes of saline injected after the hysterectomy were compared. A significant association exists between uterine cavity volumes measured by sonohysterography and true volumes measured immediately after hysterectomy (p = 0.001). The association between uterine cavity volume measured by sonohysterography and using only a Foley catheter balloon was statistically insignificant (p = 0.13). A statistically significant positive association was observed between the uterine cavity volume and the patient's age and parity (p ⩽ 0.05). Measuring the uterine cavity volume using a paediatric Foley catheter balloon coupled with sonohysterography offers an objective approach to measuring a normal (without gross pathologies) uterus volume. This technique would improve the diagnostic accuracy and the management of women with distinct uterine cavity morphologies.

A comparative clinical study between laparoscopic-assisted vaginal hysterectomy versus nondescent vaginal hysterectomy in benign pathological conditions

Abstract Background: The need of hour is an ideal hysterectomy surgery which has shorter operative time and shorter duration of hospital stay, early resumption to work, avoidance of disfiguring scar on abdomen, and less postoperative morbidities. Nondescent vaginal hysterectomy (NDVH) and laparoscopic-assisted vaginal hysterectomy (LAVH) are both minimally invasive surgeries with more benefits than total abdominal hysterectomy. Objective: To compare NDVH and LAVH in terms of operating time for surgery, intraoperative blood loss, intraoperative, and postoperative complications. Materials and Methods: A hospital-based prospective comparative study was carried out among 50 cases requiring hysterectomy. Detailed history was collected and thorough examination was conducted in 25 women who underwent LAVH and 25 women who underwent NDVH as per the standard operating guidelines. Parameters such as blood loss, duration of surgery, duration of hospital stay, intraoperative and postoperative complications, pain score, and time taken for ambulation were compared in the two groups. Results: Both the groups were comparable in terms of age, body mass index, comorbidities present, size of the uterus, past history of surgery, and diagnosis (P &gt; 0.01). Both the groups were comparable for intraoperative or postoperative complications (P &gt; 0.01). The mean blood loss, time taken for ambulation, pain score, and duration of hospital stay were significantly lesser (P &lt; 0.01) in the LAVH group compared to the NDVH group even though the duration of surgery was significantly (P &lt; 0.01) more in this group. Conclusion: We conclude that LAVH has more advantages over NDVH and should be incorporated in selected patients requiring hysterectomy.

Retrospective analysis of hysterectomies done for benign conditions at a tertiary care hospital in South India over a two year period

According to the statistics, hysterectomy is the most common procedure done in South India with the highest rates in Andhra Pradesh and Telangana. The present study was carried out to analyze patient characteristics, common causes and route of procedure, rate of concurrent oophorectomy, and complication rates. A retrospective study was conducted using medical records. The patient characteristics who had undergone hysterectomy for benign conditions were noted in a questionnaire along with the indication for surgery, operative findings, comorbidities, and complications. Overall, 243 patients were recruited of whom the majority (62%) had undergone total abdominal hysterectomy. The mean age was 43.4 ± 9.6 years. The most common cause for the procedure was abnormal uterine bleeding (78%). Twenty percentage had associated comorbidities during admission. The complication rate was 13.5%, and postoperative fever was the most common. Concurrent oophorectomy was done in 46% of cases. Increased age and parity were in more favor of vaginal hysterectomy (P = 0.00). The mean length of stay (LOS) in the hospital was 6.4 ± 2.9 days and was influenced by surgical procedure (P = 0.016), occurrence of complications (P = 0.00), and concurrent oophorectomy (P = 0.00). We conclude that the route of the procedure, the presence of complications, and concurrent oophorectomy influenced the LOS in the hospital.

Coexistence of ovarian cancer and peritoneal tuberculosis: a case report.

Peritoneal tuberculosis (TB) is known to mimic advanced ovarian cancer. In this case report, we describe a unique case of ovarian cancer (endometrioid carcinoma grade 3) at the International Federation of Gynecology and Obstetrics (FIGO) stage IC1 with pulmonary and peritoneal TB, which was suspected preoperatively to be a coexistence of advanced ovarian cancer and pulmonary TB. A 68-year-old woman presented with a prominent abdominal mass and fever. Laboratory investigations, imaging, and sputum analysis indicated a probable diagnosis of ovarian cancer at FIGO stage IIIC, characterized by peritoneal dissemination and para-aortic lymph node metastasis, which was further complicated by coexisting pulmonary TB. Surgical management included total abdominal hysterectomy, bilateral salpingo-oophorectomy, and partial omentectomy. Intraoperatively, the tumor was localized to the right ovary with significant peritoneal thickening and adhesions indicative of peritoneal TB. The surgery was completed without apparent complications. Postoperative histopathological evaluation confirmed grade 3 endometrioid carcinoma in the right ovary along with evidence of peritoneal TB. Given the extent of adhesions attributed to TB, lymph node dissection for staging was deemed challenging and was thus not pursued. Initiation of anti-TB treatment on postoperative day 2 resulted in marked regression of the preoperatively identified pulmonary nodules and para-aortic lymph node enlargement, suggesting their inflammatory origin from TB. Although postoperative chemotherapy is typically advocated for patients with stage IC1 endometrioid carcinoma grade 3, the patient opted against it. Consequently, no adjuvant therapy was administered and the patient remained under close observation.

Preventive Dose of Melatonin on Postoperative Pain in Total Abdominal Hysterectomy: A Clinical Trial Study

Preventive Dose of Melatonin on Postoperative Pain in Total Abdominal Hysterectomy: A Clinical Trial Study

Myomatous Erythrocytosis Syndrome with Abnormally High Hemoglobin Level: A Case Report

Myomatous Erythrocytosis Syndrome is a rare condition characterized by a myomatous uterus, erythrocytosis that spontaneously returns to normal red blood cells count after removal of the myomas. The etiology of this syndrome is still unknown but it has been observed that after myomectomy or hysterectomy the red blood cells count returns to normal. This case reports a 57 years old woman who presented with postmenopausal vaginal bleeding, a myomatous uterus of 16.2 x 16.1 x 22.6 cms, RBC 8.19 x 1012/L, Hemoglobin 21.5 g/dL, Hematocrit 67.1% and Erythropoietin of 23 mIU/mL. She was experiencing heavy postmenopausal bleeding and lower abdominal pain such that she consented to undergo a total abdominal hysterectomy with bilateral salpingo-ophorectomy. Two weeks after hysterectomy her hematology parameters reduced to normal levels, erythropoietin level was 8.2 mIU/mL. Histology results of the uterus showed leiomyomas, all the other symptoms resolved. It is suspected that erythropoietin from the myomas was responsible for the high RBCs, and the patient did not need any other treatment.

P-80 A rare case of papillary thyroid carcinoma within a mature cystic ovarian teratoma

Abstract Introduction Mature teratoma is the most common ovarian germ cell neoplasm. Teratomas can contain various tissue groups, such as skin, hair, and thyroid tissue. Teratomas in which more than 50% of the tumor tissue is composed of thyroid tissue are defined as Struma Ovarii. Malignant transformation of Struma Ovarii has been reported at a rate of 0.5-5%, most commonly presenting as thyroid papillary and follicular carcinomas. Metastasis is observed in 5% of malignant cases. Clinical Case A 45-year-old female with a history of Hashimoto's thyroiditis presented in July 2022 with complaints of abdominal pain. Abdominal contrast-enhanced tomography revealed a hypo dense lesion 5 cm in diameter the right adnexal region, and in the magnetic resonance images 5 cm mass was observed in the right adnexal area. Serum Ca-125 level was 212 U/mL (0-35) at admission. Due to high suspicion of malignancy ovarian cystectomy has been performed. Pathology of specimen revealed a 0.5 cm thyroid papillary carcinoma with follicular variant in infiltrative features but no lymphovascular invasion. Subsequently, the patient underwent a total abdominal hysterectomy and bilateral salpingo-oophorectomy due to the unverifiable risk of malignancy. Pathological examination showed no malignancy. The patient presented to our clinic in June 2023, neck ultrasound revealed a 13×12 mm heterogeneous hypoechoic thyroid nodule with thick and thin septations and occasional internal vascularity in the left thyroid lobe. Fine-needle aspiration biopsy of the thyroid was performed, and cytology results were reported as benign. The serum thyroglobulin level was found to be 83.7 ng/mL. In terms of the treatment plan, BRAF and K-RAS gene analysis was planned based on the pathology preparations. The patient will be evaluated for total thyroidectomy/radioactive iodine ablation/no treatment based on the results. Follow-up is ongoing, and test results are awaited. Conclusion Malignant transformation of mature teratoma is rare and thyroid papillary carcinoma being the most frequently seen malignancy. There is no consensus on treatment and follow-up, but it is recommended to classify patients based on their risks and consider options such as total thyroidectomy/radioactive iodine ablation/no treatment for follow-up. Literature suggests the need for guidelines and treatment algorithms for the management of malignant struma ovarii. Some authors recommend whole-body iodine scanning in determining risk and follow-up, asserting that iodine-based treatment and follow-up methods would be meaningless without thyroidectomy. There is also an approach advocating for only salpingo-oophorectomy in low-risk patients and subsequent follow-up. Thus, a consensus on guidelines and treatment algorithms for malignant struma ovarii is needed.

Examining the changes in women's lives after the hysterectomy operation: Experiences of women from Turkey.

The aim of the study is to examine what kind of changes the operation has brought about in the social and psychological life of women. The study was a hermeneutic-phenomenological research conducted using qualitative research methods. It took place between May and July 2023 at a university hospital located in Istanbul, Turkey. Following ethical approval, the study included a total of 24 women who had undergone a 'total abdominal hysterectomy, bilateral salpingo-oophorectomy.' These participants were selected using a combination of maximum diversity sampling and random sampling methods. Data collection was carried out using a semi-structured interview form. The interviews were conducted using face-to-face interview techniques and in-depth interview methods. Qualitative data analysis involved using the coding paradigm of Grounded Theory and Straus and Corbin's coding framework. For the analysis of quantitative data, SPSS version 28.0 was employed, while qualitative data were analyzed using MaxQDA Analytics Pro 2022. The study found that the participants had a mean age of 47 ± 7.53, and the majority, 66.7%, had not reached menopause before the operation. The qualitative analysis of the semi-structured interviews revealed five main themes, which were identified as follows: 'hysterectomy experiences', 'the impact of hysterectomy on sexual life', 'the significance attributed to the uterus', 'the significance attributed to femininity', and 'self-efficacy after hysterectomy'. The study revealed that women experienced changes in self-perception, body image, a sense of organ loss, and developed negative attitudes towards menopause following a hysterectomy. Additionally, there was a noticeable connection between the meanings attributed to the uterus and femininity, which was often influenced by cultural and social factors. In light of these findings, it is recommended that women receive counseling from healthcare professionals before undergoing a hysterectomy. This guidance can help women better understand and cope with the physical, emotional, and cultural aspects of the procedure.

To assess the analgesic efficacy of adjuvant magnesium sulfate added with ropivacaine over ropivacaine alone as a continuous infiltration in total abdominal hysterectomy wound: A randomized controlled trial.

Magnesium sulfate (MgSO4) has been demonstrated to have analgesic property in various clinical settings. This study explores if addition of MgSO4 to ropivacaine increases its analgesic efficacy when infiltrated continuously in the postsurgical wound following total abdominal hysterectomy. This randomized controlled trial was conducted at a tertiary care referral hospital in New Delhi, India. Fifty-two patients were randomized into two groups to receive the intervention of which 48 were able to complete the study. The first group (n = 26) received 0.25% ropivacaine infiltration and the second group (n = 26) received 0.25% ropivacaine with 5% MgSO4 at the incision site for 48 h postoperatively. Primary objective was to compare the total postoperative opioid (morphine) consumption by the study participants in both the groups and the secondary objectives were pain scores at rest and at movement, patient satisfaction score, and wound quality of life on the 7th postoperative day among the two groups. Both the groups were comparable in their demographic characteristics. The median morphine consumed at 48 h postoperatively was 16.5 [0-77] mg in the ropivacaine group and 13[1-45] mg in the ropivacaine with MgSO4 group and the difference was statistically insignificant (P = 0.788). There was no statistical difference between the groups with respect to the pain scores, patient satisfaction, or wound quality of life at 7 days. The addition of MgSO4 to ropivacaine does not confer any additional postoperative analgesic benefits over ropivacaine alone in continuous wound infiltration following total abdominal hysterectomy.

Comparison of Post Operative Analgesic Efficacy of Dexamethasone as an Adjuvant with Ropivacaine 0.25% and Plain Ropivacaine 0.25%, Using Ultrasound Guided Tap Block after Total Abdominal Hysterectomy: A Randomized Controlled Trial

Introduction: Following abdominal surgery, transversus abdominis plane (TAP) block, a peripheral nerve block, can be a useful supplement to multimodal postoperative analgesia. The aim was assessment of postoperative analgesic effectiveness of 0.25% ropivacaine with 4 mg of dexamethasone on each side and 0.25% ropivacaine alone in the management of postoperative pain following total abdominal hysterectomy (TAH). Materials and Methods: Sixty adult patients planned for elective TAH with ASA Grades I–II under general anesthesia participated in this prospective, randomized, double-blinded study. Patients of Group A were given 20 mL of 0.25% ropivacaine on both the sides and Group B patients were given 20 mL of 0.25% ropivacaine with dexamethasone 4 mg on each side. The primary objective of this study was a comparison of Visual Analog Scale (VAS) scores between the groups and comparison of mean time of first rescue analgesia. The secondary objectives of this study were a comparison of hemodynamic parameters, postoperative analgesic requirement, patient satisfaction, and incidence of side effects. Results: VAS shows no discernible variation in 1 and 4 h after administration of block in Groups A and B. However, a significant difference appeared in VAS 8 h (P = 0.007), VAS 12 h (P = 0.000), and VAS 24 h (P = 0.000) after the administration of block between Groups A and B. The median time for first rescue analgesia was 2.75 h (interquartile range [IQR] = 1 h) and 5.8 h (IQR = 1.6 h) in Groups A and B, respectively, which was highly significant. Conclusion: We concluded that, after abdominal hysterectomy, dexamethasone added to ropivacaine TAP block tends to prolong postoperative analgesia and decrease the need for analgesics.