Similar to benzodiazepines, gabapentinoids are used to reduce central nervous system hyperexcitability. Unlike benzodiazepines, gabapentinoids are not approved by the U.S. Food and Drug Administration for the treatment of psychiatric disorders, even in disorders characterized by excitatory-inhibitory imbalances in neuronal circuits. The current article explores the indications, concerns, trends in prescribing, and clinical guidance offered to clinicians for making safe decisions regarding use of gabapentinoids.

Purpose: To assess and quantify the relationship between rumination and depression among adolescents, while also exploring the potential moderating factors that could influence this relationship. Method: PubMed, Embase, Cochrane Library, Web of Science, CNKI, Wanfang Data, CBM, and VIP were searched for records published from inception to February 28, 2024. Two researchers independently screened studies, extracted data, and assessed research quality. Meta-analysis was performed using Stata 17.0. Results: A total of 29 studies involving 24,087 adolescents were included. The meta-analysis, using a random-effects model, revealed a strong correlation of 0.61 (95% confidence interval [0.60, 0.62]) between rumination and depression. Subgroup analyses indicated that the correlation was stronger among middle school students, in female-dominated samples, in European studies, in developed countries, and in research published before 2015. In addition, studies with larger sample sizes showed a stronger correlation. Conclusion: This meta-analysis confirms a significant correlation between rumination and depression in adolescents, suggesting that rumination may play a pivotal role in adolescent mental health. Findings provide crucial evidence for shaping effective prevention and intervention strategies aimed at mitigating depression in this vulnerable population.

Suicide rates among young adult women in South Korea are increasing, yet prevention programs often overlook complex psychological factors influencing suicide risk. The current study examined the impact of posttraumatic stress disorder (PTSD), impulsivity, and self-disgust on suicidal behavior in this population. Using a descriptive, cross-sectional design, 233 community-dwelling young women from eight South Korean regions participated. Data were collected from September to October 2024 through validated self-report measures assessing demographic characteristics, PTSD, impulsivity, self-disgust, and suicidal behavior. Analyses included descriptive statistics, t tests, analysis of variance, Pearson's correlation, and multiple regression. Regression analysis showed that PTSD (β = 0.17, p = .003), impulsivity (β = 0.14, p = .011), and self-disgust (β = 0.34, p < .001) significantly predicted suicidal behavior. The model explained 44.6% of the variance (F = 16.2, p < .001). PTSD, impulsivity, and self-disgust are key factors contributing to suicidal behavior in South Korean young women. Findings highlight the need for trauma-informed, stigma-free nursing education and practice, and further research to develop targeted, culturally sensitive suicide prevention.

The current pilot study evaluated the effects of a dementia simulation program, the Virtual Dementia Tour®, on empathy in family caregivers of persons with dementia (PWD) using quantitative and qualitative approaches. Study design was a pre/post quantitative survey and postintervention focus groups. Quantitative analysis used descriptive statistics of changes in responses to the Empathy and Understanding in Dementia Index (EUDI). A focus group discussion guide was developed based on Kolb's Experiential Learning Theory. Thematic analysis was conducted for qualitative data. Mean scores increased in responses to 14 of 15 items of the EUDI. Qualitative analysis yielded three major themes: Empathy, Dementia Knowledge, and Challenges. Dementia simulation programs increase empathy in family care-givers. Participants identified a need for others to participate to increase empathy and improve caregiving strategies. Research including a broader population is needed. Nurse clinicians should implement empathy-enhancing interventions to support caregivers of PWD.

To examine global publication trends, thematic developments, and emerging priorities in research on physical restraint from 2005 to 2024. The current bibliometric analysis was conducted using original research published in English between 2005 and 2024, retrieved from the Science Citation Index Expanded database. Analyses of publication trends, institutional and geographic productivity, and author keyword networks were performed using Bibliometrix. A total of 1,154 articles were identified, with a 5.5% annual growth rate. Long-term care and dementia, intensive care sedation and delirium, psychiatric coercion, and health care professionals' knowledge and attitudes emerged as dominant themes. Thematic evolution revealed a shift from sedation protocols and agitation management to ethical issues, and a recent emphasis on dementia care, behavioral assessments, and interventions. The field has transitioned toward ethical reflection and interdisciplinary restraint reduction. Future priorities include exploring non-institutional contexts and integrating technology for restraint-minimizing care models.

The current study aimed to investigate the effects of a nurse-led progressive relaxation exercise (PRE) program on the severity of psychiatric symptoms and mental well-being in individuals with schizophrenia. The study was conducted in three community mental health centers (CMHCs) in two provinces in the southeast and east Anatolia regions, using a quasi-experimental pre-/posttest control group design. The sample comprised individuals diagnosed with schizophrenia who regularly received health care services at a CMHC (N = 90; n = 45 in the intervention group, n = 45 in the control group) and met research criteria. PRE, delivered by psychiatric-mental health nurses (PMHNs), was found to effectively reduce psychiatric symptoms and increase mental well-being in individuals with schizophrenia. Mean pretest total score on the Brief Psychiatric Rating Scale was 47.87 (SD = 18.61), whereas mean posttest total score was 39.22 (SD = 16.28). Mean pretest total score of the Warwick-Edinburgh Mental Well-Being Scale was 39.96 (SD = 10.67), whereas mean posttest total score was 50.42 (SD = 8.06); these differences were statistically significant (p < .05). According to results of the current study, PRE is recommended as an evidence-based, complementary treatment that can easily be integrated into the routine care of individuals with schizophrenia by PMHNs and other mental health professionals.

Rural Hispanic/Latino older adults experience significant mental health disparities due to intersecting factors of aging, culture, and geographic isolation. From a nursing perspective, addressing these gaps requires understanding cultural values, such as familismo, respeto, and religious coping, which influence symptom expression and help-seeking behaviors. Nurses in rural settings often serve as the first point of contact, making culturally sensitive screening and recognition of somatic presentations critical for timely diagnosis and treatment. Structural barriers include language differences, provider shortages, financial constraints, transportation challenges, and immigration fears, which are intensified in rural settings. Integrating mental health services into primary care, leveraging promotores de salud, and partnering with trusted community-based institutions can enhance engagement and trust. Nursing research should prioritize culturally adapted interventions, telehealth strategies for low-literacy populations, and workforce development to increase bilingual, bicultural providers. A nursing-led, culturally responsive approach is essential to close mental health gaps for this population.