Pharmacology, the science of drug action, has helped to elucidate many basic physiological and pathological mechanisms in health and disease. Various animal experimental models have been designed to study the effect of drugs on living organisms and isolated tissues. These give an insight about where and how a drug acts, the mode of action of a drug, its effect on various body systems and probable adverse effects before administration of a drug. Therefore, the object of pharmacology is to provide such scientific data in animals as well as humans, which forms the basis of rational therapeutics. The Jalamahabhuta is fundamental base of origin for kapha dosha and mootra. These are supposed to have Asray-Asrayi Sambandha . It means these are directly proportional to each other. So by using the drug which is having the mootrala property Kapha may be controlled. Here an effort is made to prove this concept with modern parameters like immunomodulation, anti-inflammatory and antihistaminic activity.

Amavata is term derives from the word as Ama and vata.Ama is a type of metabolic toxin; it is an essential factor in development of pathology.Mandagni (low digestive fire) produce Ama in the body,when ama get associated with vitiated vata and starts circulating in the body accupies in shleshmal sthana(asthi sandhi) results in painful disease Amavata. Madhavakara (900 AD) has identified first time the disease.Amavata as seprate entity and discribed the disease in detail.Madhavakara describes etiopathology of amavata that the person with weak digestion (Mandagni) if he is posseses a secondary life (nishchalasya)or if he indulges into virrudha aaharaand vihara e.g.excessive exercise after taking heavy and fatty food,ama is produced and vata get vitiated. This ama provoks by vata (Vayuna preritah),Circulates in the body especially towards shleshmal sthanas. the resultant of cardinal symptoms of amvata are painful swelling of the joints (sarujashotham ) of hands,feet,ankle,knee,hip,Spinal column,and stiffness(jadyata),fever( Jwara),loss of appetite (aruchi),indigestion (apaka),Constipation(vibandhata),gurguling(antrakujanam)etc. this impairs the day to day functions of person.in spite of presence of NSAID,DMRD,steroids etc. the rheumatology remains refractory to treatment but Ayurvedic drug which are therapeutically safe and effectiveness.

Now a days, people are comparatively much more conscious about their skin care as it’s a compulsory part of their personality building for this purpose people are using a number of products prepared chemically, which ultimately harms their skin cosmeceuticals are one of such product So, it is better to follow the herbal care for the skin, most herbal skin care product don’t have any side effects. Moreover herbal skin care drugs can be easily made at home, hence making them even more attractive, so herbal skin care is the way to go4. Hence, study of Ayurvedic drugs and the preventive aspects which describe skin care in Ayurvedic compendia is necessiated, which will help in curing various skin problems1 .

Diabetes Mellitus is a major health problem in the whole world. In spite of tremendous advancements of the modern system of medicine as OAD (oral anti-diabetic drug) and insulin therapy, to date, an ideal drug that can control hyperglycemia is still a distant dream. It has been a challenge for Ayurveda to search for additional effective solutions resulting in the better management of the disease. There is a need for effective, safe and potent medicine which can control hyperglycemia related to type II diabetes and has no side effects. In this case study, we used Ayurvedic medicine ‘Vallipanchmoolchurna’ mentioned in Sushruta Samhita in a single case study which was done on the use of Vallipanchmool churna on type II Diabetes Mellitus. A significant reduction was seen in blood sugar level fasting and post-meal.

Acharya Sushruta has described 107 marmas. Marma is constituted as combination of Mamsa (muscle), Sira (vessels), Snayu (nerve, tendon, ligament), Asthi(bone) and Sandhi (joints).This five tissue participate to play vital role in any injury that occur to any of the marma. Kurpara marma is located at the junction of bahu (arm) and prabahu (forearm) i.e exactly at the elbow joint in both the upper limbs. Kurpara marma is one of the Vaikayalkara marma (loss of function). Vaikalyakara marma means the marma which causes deformity on getting injured.. An injury to this marma causes deformity, pain and swelling. The articulating surfaces that form the elbow joint occurs between the trochlea and capitulum of humerus and trochlear notch of the ulna and head of radius. Elbow joint is responsile of flexion and extension of the upper limb.Tennis elbow is one of the common disease that occur on lateral side of the elbow due to Sprain of radial collateral ligament and tearing of fibres of the extensor carpi radialis brevis.It causes pain and restricted moment of the hand. Preventive measures can be used to reduce the symptoms and lessen the pain.

Immunization has been one of the biggest success stories of modern medicine. The WHO estimates that at least 10 million deaths were prevented between 2010 and 2015.Ayurveda upholds the unique principles of strengthening innate resistance of an individual in prevention and cure of diseases which is inculcated from the time of conception.The bala or vyadhikshamatva is the functional aspect of ojus.Vyadhi utpadak pratibandhakatva and Vyadhibala virodhitva which are the two aspects of vyadhikshamatva are determined and controlled by the state of Ojus.The immunomodulation is done through the medium of medicines at proper age, dose and state of body along with proper diet,regimen and state of mind. The study explores the immuno modulation strategies in children through a literature survey through the Brhat trayee and kaumarabhritya classics like Kashyapa samhitha,Arogya kalpadruma along with relevant online articles..”Prakara yoga” will be elaborated for its immunomodulatory action.An experience survey among ayurveda experts for the use of methodologies for use and practicality of these strategies also is included. Key words : immunomodulation,vyadhikshamatva,ayurveda.

Rasayan is a branch of the Ayurveda. Charaka had described fulfilling the aim of the Ayurveda i.e., drugs act by preventing old age and diseases in the healthy person. Charaka stated about two types of medicine, one which promotes resistance to the body and another which cures diseases and Rasayan therapy play a key role in achieving these goals The main aim of Rasayan therapy is to promote the formation of or resistance which in modern terminology can be called as promoting the strength of the immune system. Bhallataka, a medicinal drug has the ability to penetrate deeply into the tissues and rejuvenate the body that’s why it was used to hold in high esteem by ancient sages of Ayurveda. Maharshi Charak emphasized the Rasayana property of Bhallataka and described ten types of preparations with it. He considered bhallataka as the best drug to cure the kaphaj vyadhi. Charak has categorized Bhallataka as Dipaniya -an appetizer, Bhedaniya- to break accumulated doshas, mutra sangrahaniya- antidiuretic, and Kusthaghna -antidermatosis. In the present study, review of the drugs had been made from Ayurveda classics. Because it is important to have an awareness regarding the Poisonous drugs, when used in the proper form & prescribed dose they act as a potent therapeutic agent. It is a fact that virtually any substance can be harmful at high enough concentrations as rightly quoted that “All substances are poisons; there is none which is not a poison. The right dose differentiates a poison from a remedy.”

In literal terms Chikitsa means treatment i.e. the manner in which the medicines are applied, what medicines are to be applied or consumed to establish harmony between the doshas and root out the disequilibrium between the factors responsible for the physiological functions of the body Panchakarma therapies are usually employed to eradicate the vitiated Doshas and aid in maintaining the equilibrium of these Doshas, which is the fundamental basis of health. Purva-karma is done by snehan and swedan under the supervision of an Ayurvedic therapist. In scheduled treatment, snehan is followed by swedan. This article gives an insight on bahir parimarjan chikitsa before shodhan karma.

The qualitative and quantitative aspects of longevity are programmed from the intricate, but systematic embryogenesis which can be tailored wholesome through the clinical intervention of Ayurvedic strategies at different levels ie,even before conception and during conception. The Avayava Utpatti Sidhanta reckoned in the context of Garbha Avakranti is a key to the susceptibility to vitiation (Nidana) and the ways of breaking the pathology ( Samprapti vighatana) by the guidelines to pacification and purity of Dosha and Dhatus involved in utpatti krama. Since chikitsa comprises Nidana parivarjana and Samprapti vighatana, the present review explores the possibilities of Avayava Utpatti Sidhanta in a clinical perspective.

The covid-19 Pandemic in India is part of the worldwide pandemic of coronavirus disease 2019 (Covid-19) caused by severe acute respiratory syndrome Corona virus 2 . The disease originates through bats and spread from unknown mediums to People. Ideally, the condition is spread by Inhalation or close contact with the infected patient’s Droplets. Incubation Periods in between 2 and 14 days there are so many infections and Death that have been caused by the disease. The symptoms of the disease include fever, cough, sneezing, sore throat, difficulty in breathing, generalized weakness. The diagnosis of the disease depends upon multiple symptoms of the upper and lower respiratory tract. Based on the available evidence, various clinical guidelines for the management of COVID-19 have been formulated. Ayurveda has documented the first reference of epidemics as Janapadodhwamsa and has given a scientific insight into its causes, effect, and prevention along with management strategies. This article intends to compile and summarise guidelines from esteemed organizations along with their implication in the Indian ethical scenario and offers an easy tool for clinicians managing pregnant women in times of COVID-19. The clinical profile of COVID-19 matches with Vata-Kapha dominant Sannipataja Jwara for which detailed treatment guidelines and an array of pharmaceutical preparations are described in Ayurvedic literature which are being practiced by qualified Ayurvedic physicians effectively for long. This highlights the Ayurvedic perspective of the COVID-19 along with its prevention, prophylaxis and management strategies through Ayurveda