Society is going through a pandemic because of COVID-19 originating in Wuhan (China), which has triggered crises in all the nations of the world, which has transformed daily life, due to the measures taken by governments to stop the increase in infections. However, isolation, quarantine, concern, and fear of contagion and/or death have directly affected mental health. La sociedad esta atravesando por una pandemia como consecuencia del COVID- 19 origina en Wuhan (China) que ha desencadenado crisis en todas las naciones delmundo, que ha transformado la cotidianidad, debido a las medidas tomadas por los gobiernos para detener el aumento de contagios, sin embargo, el aislamiento, la cuarentena, la preocupacion y temor por el contagio y/o muerte ha afectado directamente la salud mental.

It is a great honor to be Guest Editor of this special number of Gaceta Medica de Caracas. We especially appreciate the invitation of the Board of Directors of the Medicine Academy and the Editor-in-Chief, Dr. Manuel Velasco, to prepare this supplement, as well as the great support, received from the Senior Editor, Dr. Anita Stern Israel. Since 2020 we have experienced the COVID-19 pandemic which has had an impact on many aspects, not only affecting lives and health, but also livelihoods, economy, and behaviors. The spread of COVID-19 in Indonesia is now increasingly widespread, with the number of cases exposed to COVID-19 increasing day by day.

Background: Coronavirus disease 2019 (COVID-19) is a highly contagious disease caused by severe acute respiratory distress syndrome coronavirus 2 (SARS-CoV-2) and comes with various degrees of severity from mild to critical conditions. This study aims to evaluate and clarify the roles of serum HDL-c and LDL-c levels in predicting the COVID-19 severity.