Household mold is a major problem in communities which face natural disasters such as hurricanes or flooding, and in homes with other sources of significant water intrusion; a biomarker for exposure to indoor mold could support public health investigations. We analyzed serum from 132 children with asthma living in government-subsidized housing for six microbial volatile organic compounds (2-ethyl-1-hexanol, 2-heptanone, 2-hexanone, 3-methylfuran, 3-octanone, and geosmin) using GC-MS. Fewer than 10% of the samples for three compounds (2-ethyl-1-hexanol, 2-heptanone, and 2-hexanone) were quantified below the limit of detection. Associations between mold/water damage variables and microbial volatile organic compounds (mVOCs) were assessed via regression analyses, adjusting for urinary cotinine and self-reported home characteristics. Children with household mold (assessed by occupant report of visual mold, mold odor, or water damage) had 32% higher serum concentrations of 2-hexanone than those living in homes without reported mold or water damage. We investigated indoor tobacco use via urinary cotinine analysis of a "first morning void spot sample" (FMV) and found that children with higher urinary cotinine had significantly higher serum 2-ethyl-1-hexanol. We found that children in homes where residents reported tobacco smoking indoors had significantly higher serum 2-ethyl-1-hexanol compared with those without reported household smoke exposure. Tobacco smoke, indoor painting, gas stoves, and carpets were not confounders in the relationship between mVOCs and mold/water damage variables. 2-hexanone, along with an index variable which included all detectable mVOCs in our panel, are promising biomarkers of recent mold exposure that could be used in concert with other detection methods.

Arsenic in drinking water poses a threat to public health world-wide. In March 2001, the EPA revised the maximum contaminant level (MCL) for arsenic in drinking water downward from 50 µg/L to 10 µg/L and required all U.S. small community water systems (CWSs) and non-community water systems (NCWSs) to comply by 23 January 2006. Much of the financial burden associated with complying with and maintaining this new drinking water MCL was shouldered by local community governments. For example, the Walker River Paiute Tribe operated a CWS on the Walker River Paiute Indian Reservation that needed upgrading to meet the new arsenic MCL. In collaboration with the Walker River Paiute Tribe, we conducted a study to assess whether reducing the arsenic concentration in drinking water to meet the new MCL reduced the arsenic body burden in local community members who drank the water. Installing a drinking water treatment to remove arsenic dramatically reduced both the drinking water concentrations (to below the current EPA MCL of 10 µg/L) and the community members’ urinary concentrations of total As, AsIII, and AsV within a week of its full implementation. Additional assistance to small water systems to sustain new drinking water treatments may be warranted.

Surface sanitation is used to mitigate the transmission of infectious agents and is the collective process of washing a surface then rinsing it with potable water to remove debris and residual cleaning agent. If necessary and depending on surface type, contamination event, or regulatory requirement, an antimicrobial agent (chemical sanitizer or disinfectant) registered with the Environmental Protection Agency or heat (steam or hot water) can be applied to the surface to reduce or inactivate pathogenic microorganisms. The absence of universally defined terms and regulations pertaining to the various stages of surface sanitation has resulted in confusion, potentially leading to inadequate sanitation practices and persistent surface contamination. We addressed this issue by raising awareness of the significance of surface cleaning and elucidating the fundamental principles, key considerations, and potential areas for improvement concerning surface cleaning. Specific topics covered include a comprehensive description of surface cleaning, barriers hindering effective surface cleaning, correlation between contamination and foodborne disease outbreaks, and variations among cleaning agents. To maintain conciseness and relevance, the exclusive focus is on hard, nonporous surfaces, which have been identified as potential sources for the transmission of pathogenic microorganisms associated with foodborne illnesses.