Abstract
The metabolism of orally administered tracer doses of Zn65 was studied in man under strictly controlled dietary conditions during low and high calcium intake. The average intestinal absorption of radiozinc was 35.7% in the 5 patients studied during low calcium intake. There was no significant change in Zn65 absorption when the intake of calcium of these patients was increased six- to tenfold. Also, there was no correlation between the calcium balances and the absorption of Zn65, nor between the urinary excretion of calcium and of Zn65. A calcium-zinc antagonism, postulated in animal experiments, could not be demonstrated in humans under the conditions of our studies.
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