Yoğun Bakım Ünitesindeki Geriatrik COVID-19 Hastalarının Özellikleri ve Mortalite Prodüktörleri: Retrospektif Klinik Çalışma

Abstract

Objective: Although coronavirus disease-2019 (COVID- 19) is seen in all age groups, the disease may progress more severely in adults with geriatric patients and comorbidities. We aimed to determine mortality rates and factors that may affect mortality by comparing the demographic, clinical, laboratory and radiological characteristics of different geriatric age groups. Material and Methods: A total of 444 COVID-19 intensive care unit (ICU) patients aged ≥65 years who were diagnosed with COVID-19 (real-time polymerase chain reaction positive) were included in the study. The patients were classified into 3 groups according to their age: younger-aged (65-74 years old), middle-aged (75-84 years old) and advanced-aged (≥85 years old) and the groups were compared. Results: The most common hospital admission symptom of total of 444 (73.2%) patients was dyspnoea. There was a statistical difference between genders in three groups (p<0.001). There was no difference between the mortality rates of the 3 groups (p=0.097). According to multiple logistic regression analysis, age ≥85 years, lactate dehydrogenase (LDH), procalcitonin and myalgia/joint pain were determined to be the risk factors that may affect mortality (p values 0.01, 0.025, 0.033 and 0.01, respectively). Conclusion: In geriatric COVID-19 ICU patients, advanced-age (≥85 years), male gender, laboratory parameters (e.g., interleukin-6, ferritin, procalcitonin, LDH) and, dyspnoea are the risk factors that increased mortality. Mortality rate was similar in geriatric groups.