Abstract
High-energy ionizing radiation therapy is a highly effective method for destroying cancer cells. Monitoring the dose distribution during radiation therapy is extremely important to deliver an optimal X-ray dose to diseased areas and minimize radiation exposure to adjacent healthy tissues. Here, we present an X-ray acoustic (XA) dosimetry system that successfully combines a spherically focused ultrasound (US) transducer with a medical linear accelerator. The system can be potentially utilized in clinical radiation therapy as an intratherapy dosimetry tool. The measured XA signal showed good correlation with the water-absorbed dose measured with conventional dosimetry. We acquired the absorbed X-ray dose distribution in a lead sample by mechanically scanning the focused US transducer. The lateral spatial resolution of the XA signal was 2.1 ± 0.5 mm, and signal-to-noise ratio of the signal was maintained with 100-mm penetration depth, whereas that of a laser-driven photoacoustic signal was exponentially decreased.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: IEEE Transactions on Radiation and Plasma Medical Sciences
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
