Abstract
In the last two decades there have been dramatic changes in the epidemiology of Clostridium difficile infection (CDI), with increases in incidence and severity of disease in many countries worldwide. The incidence of CDI has also increased in surgical patients. Optimization of management of C difficile, has therefore become increasingly urgent. An international multidisciplinary panel of experts prepared evidenced-based World Society of Emergency Surgery (WSES) guidelines for management of CDI in surgical patients.
Highlights
C. difficile is an anaerobic, spore forming Gram-positive bacillus, which may form part of the normal intestinal microbiota in healthy newborns but which is rarely present in the gut of healthy adults [14,15,16]
Sartelli et al World Journal of Emergency Surgery (2015) 10:38 (WSES) involves many of the world’s leading surgical experts in management of Clostridium difficile infection (CDI). This expert panel includes professionals who treat CDI patients on a daily basis as well as those with research interests in the condition. These guidelines outline clinical recommendations based on the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) hierarchy criteria summarized in Table 1 [12, 13]
Recommendations Diagnosis 1) Stool testing should only be performed on diarrhea stools from at-risk patients with clinically significant diarrhea (Recommendation 1 C)
Summary
WSES guidelines for management of Clostridium difficile infection in surgical patients. Jean Louis Frossard, Rita Galeiras, Wagih Ghnnam, Carlos Augusto Gomes, Venkata Gorrepati, Mohamed Hassan Ahmed, Torsten Herzog, Felicia Humphrey, Jae Il Kim, Arda Isik, Rao Ivatury, Yeong Yeh Lee, Paul Juang, Luis Furuya-Kanamori, Aleksandar Karamarkovic, Peter K Kim, Yoram Kluger, Wen Chien Ko62, Francis D. LaBarbera, Jae Gil Lee, Ari Leppaniemi, Varut Lohsiriwat, Sanjay Marwah, John E. Frederick Alan Moore, Carl Erik Nord, Carlos A. To27, Cristian Tranà, Waldemar Uhl, Libor Urbánek, Harry van Goor, Angela Vassallo, Jean Ralph Zahar, Emanuele Caproli and Pierluigi Viale
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